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RBM19 is essential for preimplantation development in the mouse.

Jian Zhang | Amber J Tomasini | Alan N Mayer
BMC developmental biology | 2008

RNA-binding motif protein 19 (RBM19, NCBI Accession # NP_083038) is a conserved nucleolar protein containing 6 conserved RNA recognition motifs. Its biochemical function is to process rRNA for ribosome biogenesis, and it has been shown to play a role in digestive organ development in zebrafish. Here we analyzed the role of RBM19 during mouse embryonic development by generating mice containing a mutation in the Rbm19 locus via gene-trap insertion.

Pubmed ID: 19087264

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Associated grants

  • Agency: NIDDK NIH HHS, United States
    Id: R03 DK067176

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C57BL/6J (tool)

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