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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
The record is no longer available at this source.
Source Database: RGD, Rat Genome Database Strain List RGD
Genetic Background: mutant
Affected Genes: (null)
Genomic Alteration: (null)
Availability: Not Available
Source References: (null)
Notes: CRISPR/Cas9 system was used to introduce a mutation in the Tert gene of Crl:SD rat embryos. The resulting mutation is a 17-bp deletion of exon1 in Tert gene. MCW Gene Editing Rat Resource Center This is a legacy resource.
Proper citation: RRID:RGD_13207522 Copy
The record is no longer available at this source.
Source Database: RGD, Rat Genome Database Strain List RGD
Genetic Background: mutant
Affected Genes: (null)
Genomic Alteration: (null)
Availability: Not Available
Source References: (null)
Notes: The CRISPR/Cas9 genome editing system was used to generate this mutant rat strain. It inserted 55-79 copies of human premutation CGG repeats of the FMR1 gene into rat Fmr1. The recipient zygotes were from inbred strain F344 at RRRC. Rat Resource and Research Center This is a legacy resource.
Proper citation: RRID:RGD_11537344 Copy
The record is no longer available at this source.
Source Database: RGD, Rat Genome Database Strain List RGD
Genetic Background: mutant
Affected Genes: (null)
Genomic Alteration: (null)
Availability: Not Available
Source References: (null)
Notes: CRISPR/Cas9 system was used to introduce a mutation in the Avpr2 gene of SS/JrHsdMcwi rat embryos. The resulting mutation is a 5-bp deletion in Exon 2 of the Avpr2 gene. MCW Gene Editing Rat Resource Center This is a legacy resource.
Proper citation: RRID:RGD_13208586 Copy
The record is no longer available at this source.
Source Database: RGD, Rat Genome Database Strain List RGD
Genetic Background: mutant
Affected Genes: (null)
Genomic Alteration: (null)
Availability: Not Available
Source References: (null)
Notes: CRISPR/Cas9 system was used to introduce a mutation in the Avpr2 gene of SS/JrHsdMcwi rat embryos. The resulting mutation is a 8-bp deletion in Exon 2 of the Avpr2 gene. MCW Gene Editing Rat Resource Center This is a legacy resource.
Proper citation: RRID:RGD_13208585 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=401900746
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Availability: Cryopreserved Embryo; Cryopreserved Sperm (as of 2023-11-21)
Alternate IDs: RGD_401900746
Notes: CRISPR/Cas9 system was used to introduce Cre recombinase downstream of the Prl7b1 start site. Rat Resource and Research Center
Proper citation: 001013 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=616335891
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Availability: Cryopreserved Sperm (as of 2025-05-13)
Alternate IDs: RGD_616335891
Notes: Exons 2 and 3 were deleted to eliminate all known Synaptopodin isoforms in the outbred Long Evans (Charles River 006). It is similar to RRRC strain #964 (LE-Synpoem1Kmh) (RGD:155782907), has a different mutation location upstream of exon 2. This strain is deposited at Rat Resource and Research Center
Proper citation: 001025 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=401827145
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Availability: Cryorecovery (as of 2025-01-27)
Alternate IDs: RGD_401827145
Notes: The CRISPR-Cas9 system was used to delete the coding region (exons 1-8) of the Pink1 gene in NTac:SD embryos. The rat is deposited at Rat Resource and Research Center (RRRC).
Rat Resource and Research Center
Proper citation: 001007 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=10002794
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Cryopreserved Sperm (as of 2021-11-03)
Alternate IDs: 10002794
Notes: This strain was produced by injecting TALENs targeting the sequence CTTAGACAACTCTCAATAGCTttatgggcctcggccAAGCGGCATGGAAGGAGGC into Crl:SD rat embryos. The resulting mutation is a 1-bp frameshift deletion in exon 2.
Proper citation: RRID:RGD_10002794 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=2299122
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Extinct (as of 2017-01-26)
Alternate IDs: 2299122
Notes: These Sleeping Beauty mutants were derived by crossing F344-TgTn(T2/Bart3)2Ceb (RGD:2290163) and F344-Tg(PGK2-sb11)Ceb (RGD:2290169). This mutation consists of an insertion of a Sleeping Beauty transposable element gene trap construct into the 2nd intron of the Tasp1 gene.
Proper citation: RRID:RGD_2299122 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=625624
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Unknown
Alternate IDs: 625624
Notes: Eker rat is derived from the Long-Evans strain that has a mutation in Tsc2 gene. Originally reported by R. Eker in 1954 at the Norwegian Radium Hospital, Oslo.
Proper citation: RRID:RGD_625624 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=10043617
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Cryopreserved Sperm (as of 2018-04-20)
Alternate IDs: 10043617
Notes: This strain rats was provided to University of Kansas from Central Institute for Laboratory Animal Breeding (Hanover, Germany), and then was introduced to Fujita Health University. National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_10043617 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=1302620
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Live Animals; Cryopreserved Embryo; Cryopreserved Sperm (as of 2021-11-12)
Alternate IDs: 1302620
Notes: Okamoto 1963 from outbred Wistar Kyoto rats. Bred from a male with mild hypertension, mated with a female with high blood pressure. Brother x sister mating with continued selection for high blood pressure (Okamoto 1969, Okamoto et al 1972). National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_1302620 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=1358918
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Unknown
Alternate IDs: 1358918
Notes: Wistar rats were received in 1957 from Walter Reed Army Medical Center. In 1977, three ofsprings exhibited body tremor. Two of these had hydrocephalus and the brain of the third was normal. The mother rat and four of its clinically mormal youngs along with three adult males were breed as nuclear breeders.
Proper citation: RRID:RGD_1358918 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=1357186
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Unknown
Alternate IDs: 1357186
Notes: This mutation was first observed in normal Wistar albino rats in a breeding colony at Cannaught Laboratories in 1934. Jaundice was evident at birth or shortly after and was persistant throughout life. Harlan
Proper citation: RRID:RGD_1357186 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=1599757
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Extinct (as of 2016-10-24)
Alternate IDs: 1599757
Notes: Male founders are injected with ENU (N-ethyl-N-nitrosourea) and harem bred to females. The pups are genetically screened using the TILLING assay (an enzyme-based heteroduplex cleavage assay) as well as nucleotide sequencing to identify and characterize target genes possessing ENU-induced mutations. Q310L mutation is generated from the codon change CAG/CTG of rat Adora2a.
Proper citation: RRID:RGD_1599757 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=1599756
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Unknown
Alternate IDs: 1599756
Notes: Male founders are injected with ENU (N-ethyl-N-nitrosourea) and harem bred to females. The pups are genetically screened using the TILLING assay (an enzyme-based heteroduplex cleavage assay) as well as nucleotide sequencing to identify and characterize target genes possessing ENU-induced mutations. Y344Stop mutation is generated from the codon change TAT/TAA.
Proper citation: RRID:RGD_1599756 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=1579688
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Extinct (as of 2017-01-26)
Alternate IDs: 1579688
Notes: Male founders are injected with ENU (N-ethyl-N-nitrosourea) and harem bred to females. The pups are genetically screened using the TILLING assay (an enzyme-based heteroduplex cleavage assay) as well as nucleotide sequencing to identify and characterize target genes possessing ENU-induced mutations. T289M mutation is generated from the codon change ACG/ATG.
Proper citation: RRID:RGD_1579688 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=1554302
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Unknown
Alternate IDs: 1554302
Notes: Homozygous hobble rats that were taken from the inbred hobble rat colony. National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_1554302 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=1579712
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Extinct (as of 2017-01-26)
Alternate IDs: 1579712
Notes: Male founders are injected with ENU (N-ethyl-N-nitrosourea) and harem bred to females. The pups are genetically screened using the TILLING assay (an enzyme-based heteroduplex cleavage assay) as well as nucleotide sequencing to identify and characterize target genes possessing ENU-induced mutations. V135G mutation is generated.
Proper citation: RRID:RGD_1579712 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=1579681
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Extinct (as of 2016-10-24)
Alternate IDs: 1579681
Notes: Male founders are injected with ENU (N-ethyl-N-nitrosourea) and harem bred to females. The pups are genetically screened using the TILLING assay (an enzyme-based heteroduplex cleavage assay) as well as nucleotide sequencing to identify and characterize target genes possessing ENU-induced mutations.W76G mutation is generated.
Proper citation: RRID:RGD_1579681 Copy
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