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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
http://www.wormbase.org/db/get?name=WBStrain00050823
Source Database: WormBase (WB)
Affected Genes: WBGene00000903(daf-7)|WBGene00000908(daf-12)
Genomic Alteration: WBGene00000903(daf-7), WBGene00000908(daf-12)
Availability: unknown
Source References: EMPTY
Synonyms: daf-7(e1372) III; daf-12(ot874[daf-12::TagRFP::AID]) X.
Notes: Temperature sensitive dauer constitutive. Maintain at 15C. CRISPR/Cas9-engineered AID conditional daf-12 allele in daf-7(e1372) background (TIR1-less control). Reference: Aghayeva et al., submitted
Proper citation: RRID:WB-STRAIN:WBStrain00050823 Copy
http://www.wormbase.org/db/get?name=WBStrain00050829
Source Database: WormBase (WB)
Affected Genes: WBGene00004010(pha-1)
Genomic Alteration: WBGene00004010(pha-1)
Availability: unknown
Source References: EMPTY
Synonyms: pha-1(e2123) III; otEx7092.
Notes: otEx7092 [inx-18b(fosmid WRM0629cH03)::SL2::NLS::YFP::H2B + pha-1(+) + myo-2p::BFP]. Maintain at 25C or pick BFP+ to retain array. Reference: Bhattacharya A, et al. Cell. 2019 Feb 21;176(5):1174-1189.e16.
Proper citation: RRID:WB-STRAIN:WBStrain00050829 Copy
http://www.wormbase.org/db/get?name=WBStrain00050827
Source Database: WormBase (WB)
Affected Genes: WBGene00004010(pha-1)
Genomic Alteration: WBGene00004010(pha-1)
Availability: unknown
Source References: EMPTY
Synonyms: pha-1(e2123) III; otEx7075.
Notes: otEx7075 [inx-18a(fosmid WRM0629cH03)::SL2::NLS::YFP::H2B + pha-1(+) + myo-2p::BFP]. Maintain at 25C or pick BFP+ to retain array. Reference: Bhattacharya A, et al. Cell. 2019 Feb 21;176(5):1174-1189.e16.
Proper citation: RRID:WB-STRAIN:WBStrain00050827 Copy
http://www.wormbase.org/db/get?name=WBStrain00050770
Source Database: WormBase (WB)
Affected Genes: WBGene00000527(cle-1)
Genomic Alteration: WBGene00000527(cle-1)
Availability: unknown
Source References: EMPTY
Synonyms: cle-1(qy22[cle-1::mNG+loxP]) I.
Notes: Made_by: Qiuyi Chi, Daniel Keeley,Eric Hastie, Ranjay Jayad|"Superficially wild-type. CRISPR/Cas9 insertion of mNeonGreen. Insertion site verified by PCR and sequencing."
Proper citation: RRID:WB-STRAIN:WBStrain00050770 Copy
http://www.wormbase.org/db/get?name=WBStrain00050774
Source Database: WormBase (WB)
Affected Genes: WBGene00004749(sdn-1)
Genomic Alteration: WBGene00004749(sdn-1)
Availability: unknown
Source References: PMID:37039075, PMID:38964319
Synonyms: sdn-1(qy29[sdn-1::mNG+loxP]) X.
Notes: Made_by: Qiuyi Chi, Daniel Keeley,Eric Hastie, Ranjay Jayad|"SDN-1::mNG endogenous tag"|"Superficially wild-type. CRISPR/Cas9 insertion of mNeonGreen. Insertion site verified by PCR and sequencing."
Proper citation: RRID:WB-STRAIN:WBStrain00050774 Copy
http://www.wormbase.org/db/get?name=WBStrain00050771
Source Database: WormBase (WB)
Affected Genes: WBGene00001263(emb-9)
Genomic Alteration: WBGene00001263(emb-9)
Availability: unknown
Source References: PMID:38964319
Synonyms: emb-9(qy24[emb-9::mNG+loxP]) III.
Notes: Made_by: Qiuyi Chi, Daniel Keeley,Eric Hastie, Ranjay Jayad|"Superficially wild-type. Slow growth. CRISPR/Cas9 insertion of mNeonGreen. Insertion site verified by PCR and sequencing."
Proper citation: RRID:WB-STRAIN:WBStrain00050771 Copy
http://www.wormbase.org/db/get?name=WBStrain00050777
Source Database: WormBase (WB)
Affected Genes: WBGene00003242(mig-6)
Genomic Alteration: WBGene00003242(mig-6)
Availability: unknown
Source References: PMID:38964319
Synonyms: mig-6(qy37[mNG+loxP::mig-6]) V.
Notes: Made_by: Qiuyi Chi, Daniel Keeley,Eric Hastie, Ranjay Jayad|"Superficially wild-type. CRISPR/Cas9 insertion of mNeonGreen. Insertion site verified by PCR and sequencing. mNeonGreen is inserted at the N-terminus right before a putative proprotein convertase cleavage site and Western analysis indicates most of the mNeonGreen is cut from the MIG-1 protein and is diffuse in the extracellular fluid. See Figure S1 in Keeley et al., Dev Cell. 2020 Jul 6;54(1):60-74.e7. doi: 10.1016/j.devcel.2020.05.022. PMID: 32585132"
Proper citation: RRID:WB-STRAIN:WBStrain00050777 Copy
http://www.wormbase.org/db/get?name=WBStrain00050810
Source Database: WormBase (WB)
Affected Genes: WBGene00002128(inx-6)
Genomic Alteration: WBGene00002128(inx-6)
Availability: unknown
Source References: EMPTY
Synonyms: inx-6(ot804 [inx-6::SL2::NLS::yfp::H2B]) IV.
Notes: inx-6(ot804) was generated by the insertion of SL2::NLS::YFP::H2B into the endogenous inx-6 locus. Reference: Bhattacharya A, et al. Cell. 2019 Feb 21;176(5):1174-1189.e16.
Proper citation: RRID:WB-STRAIN:WBStrain00050810 Copy
http://www.wormbase.org/db/get?name=WBStrain00050775
Source Database: WormBase (WB)
Affected Genes: WBGene00001863(him-4)
Genomic Alteration: WBGene00001863(him-4)
Availability: unknown
Source References: PMID:38964319
Synonyms: him-4(qy33[him-4::mNG+loxP]) X.
Notes: Made_by: Qiuyi Chi, Daniel Keeley,Eric Hastie, Ranjay Jayad|"Superficially wild-type. CRISPR/Cas9 insertion of mNeonGreen. Insertion site verified by PCR and sequencing."
Proper citation: RRID:WB-STRAIN:WBStrain00050775 Copy
http://www.wormbase.org/db/get?name=WBStrain00050815
Source Database: WormBase (WB)
Affected Genes: WBGene00000898(daf-2)|WBGene00000912(daf-16)
Genomic Alteration: WBGene00000898(daf-2), WBGene00000912(daf-16)
Availability: unknown
Source References: EMPTY
Synonyms: daf-16(ot853[daf-16::mNeonGreen::3xFlag::AID]) I; daf-2(e1370) III.
Notes: Temperature sensitive dauer constitutive. Maintain at 15C. CRISPR/Cas9-engineered AID conditional daf-16 allele in daf-2(e1370) background (TIR1-less control). Reference: Aghayeva et al., submitted
Proper citation: RRID:WB-STRAIN:WBStrain00050815 Copy
http://www.wormbase.org/db/get?name=WBStrain00050814
Source Database: WormBase (WB)
Affected Genes: WBGene00000908(daf-12)
Genomic Alteration: WBGene00000908(daf-12)
Availability: unknown
Source References: EMPTY
Synonyms: daf-12(ot870[daf-12::GFP::3xFlag]) X.
Notes: Superficially wildtype. GFP tag inserted into endogenous daf-12 locus through CRISPR/Cas9 engineering. Reference: Aghayeva et al., submitted
Proper citation: RRID:WB-STRAIN:WBStrain00050814 Copy
http://www.wormbase.org/db/get?name=WBStrain00050816
Source Database: WormBase (WB)
Affected Genes: WBGene00000898(daf-2)|WBGene00000912(daf-16)
Genomic Alteration: WBGene00000898(daf-2), WBGene00000912(daf-16)
Availability: unknown
Source References: EMPTY
Synonyms: daf-16(ot853[daf-16::mNG::3xFlag::AID]) I; ieSi57 II; daf-2(e1370) III.
Notes: ieSi57 [eft-3p::TIR1::mRuby::unc-54 3'UTR] II. Maintain at 15C. Temperature-sensitive dauer constitutive. CRISPR/Cas9-engineered AID conditional daf-16 allele in daf-2(e1370) background with ubiquitous TIR1 expression. Reference: Aghayeva et al., submitted
Proper citation: RRID:WB-STRAIN:WBStrain00050816 Copy
http://www.wormbase.org/db/get?name=WBStrain00050763
Source Database: WormBase (WB)
Affected Genes: WBGene00006547(tbx-11)
Genomic Alteration: WBGene00006547(tbx-11)
Availability: unknown
Source References: EMPTY
Synonyms: tbx-11(luc144) III.
Notes: Made_by: Josef Rhsner|"Wild-type morphology. CRISPR/Cas9 engineered 1.3 kb deletion of the tbx-11 locus. Flanking sequence: aaaaataacaaaataacaaggaatgagaagggaaaacaggaaaaatacac / ttgccacgtgttgggcgggaaaacgcgtagtcatccggcaggtgtaacct Reference: Charest J, et al. Dev Cell. 2020 Sep 24;S1534-5807(20)30672-9. PMID: 33002421"
Proper citation: RRID:WB-STRAIN:WBStrain00050763 Copy
http://www.wormbase.org/db/get?name=WBStrain00050761
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)|WBGene00009163(drsh-1)|WBGene00011908(pash-1)
Genomic Alteration: WBGene00006843(unc-119), WBGene00009163(drsh-1), WBGene00011908(pash-1)
Availability: unknown
Source References: EMPTY
Synonyms: drsh-1(luc82[myc::AID::3XFLAG::4xGGSG::drsh-1::4xGGSG::3xFLAG::AID::myc]) pash-1(luc71[pash-1::2xGGSG::3xFLAG::AID::myc]) I; ieSi57 II; unc-119(ed3) III; ieSi38 IV; lucIs20; lucIs24.
Notes: ieSi57 [eft-3p::TIR1::mRuby::unc-54 3'UTR + Cbr-unc-119(+)] II. ieSi38 [sun-1p::TIR1::mRuby::sun-1 3'UTR + Cbr-unc-119(+)] IV. lucIs20 [mir-35p::mirtron-35 + myo-2::mCherry]. lucIs24 [mir-52p::mirtron-51 + elt-2::dsRed + myo-2::mCherry]. Endogenous drsh-1 tagged at both N- and C-termini with the auxin-inducible-degron (AID) peptide. Endogenous pash-1 tagged with the AID peptide at the C-terminus. Strain expresses modified Arabidopsis thaliana TIR1 tagged with mRuby in soma and germline. In addition, strain expresses mirtron-versions of mir-35 and mir-51, which are processed independently of Drosha and Pasha. miRNA biogenesis can be stringently inhibited via simultaneous removal of Drosha and Pasha, causing absence of all canonical miRNAs and embryonic lethality upon Auxin treatment. Reference: Dexheimer, PJ, et al. Curr Biol. 2020. in press.|"Made_by: Philipp Dexheimer"
Proper citation: RRID:WB-STRAIN:WBStrain00050761 Copy
http://www.wormbase.org/db/get?name=WBStrain00050767
Source Database: WormBase (WB)
Availability: unknown
Source References: EMPTY
Synonyms: wdIs132; uIs152.
Notes: Made_by: Seth Taylor in the Miller Lab|"wdIs132 [gcy-35::GFP]. uIs152 [mec-3::RFP]. AVM neurons are labeled with GFP and RFP. Can be used to isolate AVM by FACS. wdIs132 arose from spontaneous integration of kyEx1162 [gcy-35::GFP]. Used by CeNGEN project for RNA-Seq (https:"
Proper citation: RRID:WB-STRAIN:WBStrain00050767 Copy
http://www.wormbase.org/db/get?name=WBStrain00050800
Source Database: WormBase (WB)
Availability: unknown
Source References: EMPTY
Synonyms: jsTi1492 II.
Notes: jsTi1492 [LoxP::mex-5p::FLP::SL2::mNeonGreen::rpl-28p::FRT::GFP::his-58::FRT3] II. jsTi1492 is prone to silencing; pick animals with GFP+ germlines to maintain. jsTi1492 is an RMCE landing site inserted using miniMos located on Chr II at at 3,160,571 (WB273 genome; -8.14 m.u.) inserted in a repeat region between sri-34 and fbxc-55. Insertsion site ttttttgcaaaaaagtgcagtcataTAtgtatgtaaaaaattaattgaagac with rpl-28 transcription toward sri-34. Insertion site is ambiguous but likely near the edge of sri-34 side of the repeat region. Reference: Nonet ML. Genetics. 2020.
Proper citation: RRID:WB-STRAIN:WBStrain00050800 Copy
http://www.wormbase.org/db/get?name=WBStrain00050765
Source Database: WormBase (WB)
Affected Genes: WBGene00000483(che-1)
Genomic Alteration: WBGene00000483(che-1)
Availability: unknown
Source References: EMPTY
Synonyms: che-1(luc174) I.
Notes: Made_by: Julien Charest|"Wild-type morphology. CRISPR/Cas9 engineered 3.38 kB deletion of the che-1 locus. Flank: caaaaacatcacaaaaataa"
Proper citation: RRID:WB-STRAIN:WBStrain00050765 Copy
http://www.wormbase.org/db/get?name=WBStrain00050768
Source Database: WormBase (WB)
Availability: unknown
Source References: EMPTY
Synonyms: ynIs37 III; ufIs26.
Notes: Made_by: John Tipps in the Miller Lab|"ynIs37 [flp-13p::GFP] III. ufIs26 [unc-4p::mCherry + lin-15(+)]. I5 neurons are labeled with GFP and RFP. Can be used to isolate I5 by FACS. Used by CeNGEN project for RNA-Seq (https:"
Proper citation: RRID:WB-STRAIN:WBStrain00050768 Copy
http://www.wormbase.org/db/get?name=WBStrain00050801
Source Database: WormBase (WB)
Availability: unknown
Source References: EMPTY
Synonyms: jsTi1453 jsSi1527 I; jsTi1493 jsSi1549 IV.
Notes: jsTi1453 [LoxP::rpl-28p::FRT::GFP::his-58::FRT3] I. jsSi1527 [LoxP::lexO 5X::(delta)pes-10p::GFP-C1::FRT3] I. jsTi1493 [LoxP::mex-5p::FLP:SL2::mNeonGreen::rpl-28p::FRT::GFP::his-58::FRT3] IV. jsSi1549 [LoxP::mec-4p::lexA-L-QF::FRT-3] IV. RMCE derived single copy lexO GFP-C1 reporter line on Chr I and RMCE derived single copy mec-4p lexA-L-QF driver on Chr IV. Reference: Nonet ML. Genetics. 2020.
Proper citation: RRID:WB-STRAIN:WBStrain00050801 Copy
http://www.wormbase.org/db/get?name=WBStrain00050751
Source Database: WormBase (WB)
Availability: unknown
Source References: EMPTY
Synonyms: lucEx755.
Notes: lucEx755 [tbx-32::GFP(fosmid) + ttx-3p::mCherry]. Pick mCherry+ animals to maintain. Wild-type morphology. Extrachromosomal TBX-32 direct fusion fosmid-based reporter. Reference: Charest J, et al. Dev Cell. 2020 Sep 24;S1534-5807(20)30672-9. PMID: 33002421|"Made_by: Julien Charest"
Proper citation: RRID:WB-STRAIN:WBStrain00050751 Copy
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