Searching the RRID Resource Information Network
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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
| Organism Name | Proper Citation | Species | Synonyms |
Notes |
Phenotype | Affected Gene | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
B6.Cg-B2mtm1Unc Cd3e Resource Report Resource Website Issue |
RRID:IMSR_EM:00754 | Mus musculus |
B6.Cg-B2m |
gene symbol note: beta-2 microglobulin|histocompatibility 2; D region locus 1|CD3 antigen; epsilon polypeptide|histocompatibility 2; K1; K region; mutant strain: B2m|H2-D1|Cd3e|H2-K1 | beta-2 microglobulin|histocompatibility 2; D region locus 1|CD3 antigen; epsilon polypeptide|histocompatibility 2; K1; K region | targeted mutation 1; University of North Carolina|targeted mutation 1; Beatrice Perarnau|targeted mutation 1; Bernard Malissen | EM:00754 | European Mouse Mutant Archive | EMMA | embryo | 2026-07-24 10:29:34 | 0 | ||||
|
B6;129P2-Tcrbtm1Mom Apoe Resource Report Resource Website Issue |
RRID:IMSR_EM:00430 | Mus musculus | apolipoprotein E KO and TCRbeta KO | gene symbol note: apolipoprotein E|T cell receptor beta chain; mutant strain: Apoe|Tcrb | apolipoprotein E|T cell receptor beta chain | targeted mutation 1; University of North Carolina|targeted mutation 1; Peter Mombaerts | EM:00430 | European Mouse Mutant Archive | EMMA | embryo | 2026-07-24 10:29:33 | 0 | ||||
|
B6.Cg-Tg(Mx1-cre)1Cgn/CgnCnrm Resource Report Resource Website Issue |
RRID:IMSR_EM:01143 | Mus musculus | B6.129-Tg(Mx1-cre)1Cgn. B6-Mx1-Cre. B6.129-TgN(Mx1-Cre)1Cgn. B6.Cg-Tg(Mx1-cre)1Cgn/CgnIbcm. B6.Cg-Tg(Mx1-cre)1Cgn. B6-Tg(Mx1-cre)1Cgn/CgnIbcm | gene symbol note: transgene insertion 1; University of Cologne; mutant strain: Tg(Mx1-cre)1Cgn | transgene insertion 1; University of Cologne | transgene insertion 1; University of Cologne | EM:01143 | European Mouse Mutant Archive | EMMA | embryo | 2026-07-24 10:29:34 | 0 | ||||
|
129S2/SvPas-Ins1tm1Jja/Orl Resource Report Resource Website Issue |
RRID:IMSR_EM:01219 | Mus musculus | Ins/1_129 | gene symbol note: insulin I; mutant strain: Ins1 | insulin I | targeted mutation 1; Jacques Jami | EM:01219 | European Mouse Mutant Archive | EMMA | embryo | 2026-07-24 10:29:34 | 0 | ||||
|
STOCK Prnptm1Cwe Tg(Pcp2-Prnp)F13Zbz/Cnrm Resource Report Resource Website Issue Issue |
RRID:IMSR_EM:01836 | Mus musculus |
TgF13/Prnp |
gene symbol note: prion protein|transgene insertion F13; Zurich; mutant strain: Prnp|Tg(Pcp2-Prnp)F13Zbz | prion protein|transgene insertion F13; Zurich | targeted mutation 1; Charles Weissmann|transgene insertion F13; Zurich | EM:01836 | European Mouse Mutant Archive | EMMA | embryo | 2026-07-24 10:29:39 | 0 | ||||
|
STOCK Prnptm1Cwe Tg(Pcp2-Prnp)F332Zbz/Cnrm Resource Report Resource Website Issue Issue |
RRID:IMSR_EM:01828 | Mus musculus |
Prnp |
gene symbol note: transgene insertion F332; Zurich|prion protein; mutant strain: Tg(Pcp2-Prnp)F332Zbz|Prnp | transgene insertion F332; Zurich|prion protein | transgene insertion F332; Zurich|targeted mutation 1; Charles Weissmann | EM:01828 | European Mouse Mutant Archive | EMMA | embryo | 2026-07-24 10:29:39 | 0 | ||||
|
STOCK Prnptm1Cwe Tg(Pcp2-Prnp)E330Zbz/Cnrm Resource Report Resource Website Issue Issue |
RRID:IMSR_EM:01824 | Mus musculus |
B6.Cg-Prnp |
gene symbol note: transgene insertion E330; Zurich|prion protein; mutant strain: Tg(Pcp2-Prnp)E330Zbz|Prnp | transgene insertion E330; Zurich|prion protein | transgene insertion E330; Zurich|targeted mutation 1; Charles Weissmann | EM:01824 | European Mouse Mutant Archive | EMMA | embryo | 2026-07-24 10:29:39 | 0 | ||||
|
STOCK B2mtm1Unc H2-Ab1 Resource Report Resource Website Issue |
RRID:IMSR_EM:01783 | Mus musculus |
STOCK B2m |
gene symbol note: transgene insertion 1; Daniel M Altmann|transgene insertion 1; Beatrice Perarnau|beta-2 microglobulin|histocompatibility 2; class II antigen A; beta 1; mutant strain: Tg(HLA-DRA*0101;HLA-DRB1*0101)1Dma|Tg(HLA-A/H2-D/B2M)1Bpe|B2m|H2-Ab1 | transgene insertion 1; Daniel M Altmann|transgene insertion 1; Beatrice Perarnau|beta-2 microglobulin|histocompatibility 2; class II antigen A; beta 1 | transgene insertion 1; Daniel M Altmann|transgene insertion 1; Beatrice Perarnau|targeted mutation 1; University of North Carolina|targeted mutation 1; Christophe Benoist and Diane Mathis | EM:01783 | European Mouse Mutant Archive | EMMA | embryo | 2026-07-24 10:29:38 | 0 | ||||
|
STOCK Prnptm1Cwe Tg(Prnp)941Zbz/Cnrm Resource Report Resource Website Issue Issue |
RRID:IMSR_EM:02028 | Mus musculus |
PrPmyc |
gene symbol note: transgene insertion 941; University Hospital Zurich|prion protein; mutant strain: Tg(Prnp)941Zbz|Prnp | transgene insertion 941; University Hospital Zurich|prion protein | transgene insertion 941; University Hospital Zurich|targeted mutation 1; Charles Weissmann | EM:02028 | European Mouse Mutant Archive | EMMA | embryo | 2026-07-24 10:29:41 | 0 | ||||
|
FVB.129P2-Frat1tm1Brn Frat2 Resource Report Resource Website Issue |
RRID:IMSR_EM:02143 | Mus musculus |
F1F2. FVB.129P2-Frat1 |
gene symbol note: frequently rearranged in advanced T cell lymphomas|frequently rearranged in advanced T cell lymphomas 2; mutant strain: Frat1|Frat2 | frequently rearranged in advanced T cell lymphomas|frequently rearranged in advanced T cell lymphomas 2 | targeted mutation 1; Anton Berns|targeted mutation 2; Anton Berns | EM:02143 | European Mouse Mutant Archive | EMMA | embryo | 2026-07-24 10:29:42 | 0 | ||||
|
B6;129P2-Rhdtm1Goo/Orl Resource Report Resource Website Issue |
RRID:IMSR_EM:11706 | Mus musculus | gene symbol note: Rh blood group; D antigen; mutant strain: Rhd | Rh blood group; D antigen | targeted mutation 1; Dominique Goossens | EM:11706 | European Mouse Mutant Archive | EMMA | archived | 2026-07-24 10:30:38 | 0 | |||||
|
B6;129P2-Rhagtm1Goo/Orl Resource Report Resource Website Issue |
RRID:IMSR_EM:11707 | Mus musculus | gene symbol note: Rh associated glycoprotein; mutant strain: Rhag | Rh associated glycoprotein | targeted mutation 1; Dominique Goossens | EM:11707 | European Mouse Mutant Archive | EMMA | archived | 2026-07-24 10:30:38 | 0 | |||||
|
B6.Cg-Prnptm1Cwe Tg(Prnp*M128*D177N)FFI-26Rchi/Cnrm Resource Report Resource Website Issue Issue |
RRID:IMSR_EM:12861 | Mus musculus | gene symbol note: transgene insertion FFI-26; Roberto Chiesa|prion protein; mutant strain: Tg(Prnp*M128*D177N)FFI-26Rchi|Prnp | transgene insertion FFI-26; Roberto Chiesa|prion protein | transgene insertion FFI-26; Roberto Chiesa|targeted mutation 1; Charles Weissmann | EM:12861 | European Mouse Mutant Archive | EMMA | sperm | 2026-07-24 10:30:47 | 0 | |||||
|
B6J.Cg-Ikbkgtm1Dln Tnftm1Gkl/Mmucd Resource Report Resource Website Issue |
RRID:MMRRC_041405-UCD | Mus musculus | Research areas: Apoptosis, Cell Biology, Dermatology, Developmental Biology, Hematology, Immunology and Inflammation, Models for Human Disease, Neurobiology; Mutation Type: Targeted Mutation ; Collection: | increased bone mineral density [MP:0000062]| abnormal trabecular bone morphology [MP:0000130]| increased leukocyte cell number [MP:0000218]| increased neutrophil cell number [MP:0000219]| abnormal Peyer's patch morphology [MP:0000696]| abnormal spermatogenesis [MP:0001156]| decreased body weight [MP:0001262]| abnormal vasodilation [MP:0001613]| abnormal inflammatory response [MP:0001845]| decreased inflammatory response [MP:0001876]| abnormal glucose homeostasis [MP:0002078]| premature death [MP:0002083]| abnormal lipid homeostasis [MP:0002118]| abnormal lymph node B cell domain morphology [MP:0002344]| abnormal spleen marginal sinus morphology [MP:0002363]| abnormal Peyer's patch follicle morphology [MP:0002389]| abnormal Peyer's patch germinal center morphology [MP:0002391]| abnormal Peyer's patch T cell area morphology [MP:0002392]| decreased susceptibility to bacterial infection [MP:0002411]| increased susceptibility to bacterial infection [MP:0002412]| abnormal macrophage physiology [MP:0002451]| decreased circulating triglyceride level [MP:0002644]| oligozoospermia [MP:0002687]| decreased circulating insulin level [MP:0002727]| dilated heart left ventricle [MP:0002753]| abnormal testes secretion [MP:0002782]| colitis [MP:0002816]| abnormal cytokine secretion [MP:0003009]| rheumatoid arthritis [MP:0003561]| oxidative stress [MP:0003674]| abnormal lymphocyte physiology [MP:0003945]| abnormal spermiation [MP:0004182]| decreased incidence of tumors by chemical induction [MP:0004502]| decreased susceptibility to experimental autoimmune encephalomyelitis [MP:0004800]| decreased testis weight [MP:0004852]| abnormal testis physiology [MP:0004884]| increased osteoblast cell number [MP:0004988]| increased lymphocyte cell number [MP:0005013]| increased susceptibility to parasitic infection [MP:0005027]| cachexia [MP:0005150]| abnormal mesenteric lymph node morphology [MP:0005232]| abnormal fat pad morphology [MP:0005334]| decreased susceptibility to autoimmune disorder [MP:0005351]| decreased percent body fat/body weight [MP:0005459]| decreased circulating glucose level [MP:0005560]| decreased ventricle muscle contractility [MP:0005598]| decreased susceptibility to type IV hypersensitivity reaction [MP:0005616]| decreased circulating leptin level [MP:0005668]| decreased Peyer's patch number [MP:0008133]| small Peyer's patches [MP:0008135]| absent follicular dendritic cells [MP:0008201]| abnormal metallophilic macrophage morphology [MP:0008241]| abnormal osteoclast differentiation [MP:0008396]| abnormal spleen primary B follicle morphology [MP:0008471]| abnormal spleen follicular dendritic cell network [MP:0008473]| absent spleen germinal center [MP:0008474]| increased circulating tumor necrosis factor level [MP:0008553]| decreased circulating tumor necrosis factor level [MP:0008554]| increased tumor necrosis factor secretion [MP:0008560]| abnormal chemokine secretion [MP:0008722]| decreased susceptibility to endotoxin shock [MP:0008734]| increased susceptibility to endotoxin shock [MP:0008735]| cecum inflammation [MP:0009481]| decreased keratinocyte proliferation [MP:0009584]| prenatal lethality [MP:0011101]| incomplete penetrance [MP:0013486]| decreased Paneth cell number [MP:0030466] | Tnf||Ikbkg| | 041405-UCD | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:8879212 PMID:11179023 |
MMRRC_41405-UCD, MMRRC_041405, MMRRC_4145 | 2026-07-25 09:43:01 | 0 | |||
|
B6;129S5-Csmd1tm1Lex/Mmucd Resource Report Resource Website 1+ mentions Issue |
RRID:MMRRC_032236-UCD | Mus musculus | Research areas: Cancer, Developmental Biology, Immunology and Inflammation, Models for Human Disease, Neurobiology; Mutation Type: Targeted Mutation ; Collection: | increased body weight [MP:0001260]| increased anxiety-related response [MP:0001363]| hyperactivity [MP:0001399]| decreased startle reflex [MP:0001489]| abnormal emotion/affect behavior [MP:0002572]| behavioral despair [MP:0002573]| increased thigmotaxis [MP:0002797]| abnormal voluntary movement [MP:0003491]| improved glucose tolerance [MP:0005292] | Csmd1 | 032236-UCD | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | MMRRC_32236-UCD, MMRRC_032236, MMRRC_32236 | 2026-07-25 09:41:30 | 1 | ||||
|
B6J.Cg-Slc25a13tm1Lct/TsahMmjax Resource Report Resource Website Issue |
RRID:MMRRC_069593-JAX | Mus musculus | Research areas: Diabetes, Metabolism; Mutation Type: Targeted Mutation ; Collection: | hypoglycemia [MP:0000189]| decreased body weight [MP:0001262]| increased circulating free fatty acid level [MP:0001554]| postnatal growth retardation [MP:0001732]| premature death [MP:0002083]| hepatic steatosis [MP:0002628]| decreased circulating insulin level [MP:0002727]| increased circulating alkaline phosphatase level [MP:0002968]| abnormal gluconeogenesis [MP:0003383]| increased circulating glycerol level [MP:0003443]| increased circulating ammonia level [MP:0005309]| abnormal circulating amino acid level [MP:0005311]| abnormal amino acid level [MP:0005332]| increased liver triglyceride level [MP:0009355]| abnormal blood homeostasis [MP:0009642]| abnormal urine homeostasis [MP:0009643] | Slc25a13 | 069593-JAX | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:14701727 | MMRRC_69593-JAX, MMRRC_069593, MMRRC_69593 | 2026-07-25 09:48:29 | 0 | |||
|
B6.129S4-Atp8b1tm1Nbf/Mmucd Resource Report Resource Website Issue |
RRID:MMRRC_036310-UCD | Mus musculus | Research areas: Cell Biology, Internal/Organ, Metabolism, Models for Human Disease, Sensorineural; Mutation Type: Targeted Mutation ; Collection: | abnormal cochlea morphology [MP:0000031]| organ of Corti degeneration [MP:0000043]| enlarged liver [MP:0000599]| abnormal liver physiology [MP:0000609]| cholestasis [MP:0000610]| weight loss [MP:0001263]| postnatal growth retardation [MP:0001732]| abnormal cochlear ganglion morphology [MP:0002855]| increased circulating alanine transaminase level [MP:0002941]| increased circulating alkaline phosphatase level [MP:0002968]| increased liver weight [MP:0002981]| bile duct proliferation [MP:0003255]| cochlear inner hair cell degeneration [MP:0004398]| cochlear outer hair cell degeneration [MP:0004404]| degeneration of organ of Corti supporting cells [MP:0004465]| abnormal outer hair cell stereociliary bundle morphology [MP:0004527]| abnormal bile secretion [MP:0004772]| abnormal bile salt level [MP:0004774]| increased bile salt level [MP:0004789]| increased circulating aspartate transaminase level [MP:0005343]| increased circulating bilirubin level [MP:0005344]| abnormal bile salt homeostasis [MP:0005365]| increased sensitivity to induced morbidity/mortality [MP:0009763]| increased susceptibility to weight loss [MP:0010180]| increased or absent threshold for auditory brainstem response [MP:0011967] | Atp8b1 | 036310-UCD | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:20126555 PMID:18466903 |
MMRRC_36310-UCD, MMRRC_036310, MMRRC_3631 | 2026-07-25 09:42:04 | 0 | |||
|
129S/Sv-Atp8b1tm1Nbf/Mmucd Resource Report Resource Website Issue |
RRID:MMRRC_036309-UCD | Mus musculus | Research areas: Cell Biology, Internal/Organ, Metabolism, Models for Human Disease, Sensorineural; Mutation Type: Targeted Mutation ; Collection: | abnormal cochlea morphology [MP:0000031]| organ of Corti degeneration [MP:0000043]| enlarged liver [MP:0000599]| abnormal liver physiology [MP:0000609]| cholestasis [MP:0000610]| weight loss [MP:0001263]| postnatal growth retardation [MP:0001732]| abnormal cochlear ganglion morphology [MP:0002855]| increased circulating alanine transaminase level [MP:0002941]| increased circulating alkaline phosphatase level [MP:0002968]| increased liver weight [MP:0002981]| bile duct proliferation [MP:0003255]| cochlear inner hair cell degeneration [MP:0004398]| cochlear outer hair cell degeneration [MP:0004404]| degeneration of organ of Corti supporting cells [MP:0004465]| abnormal outer hair cell stereociliary bundle morphology [MP:0004527]| abnormal bile secretion [MP:0004772]| abnormal bile salt level [MP:0004774]| increased bile salt level [MP:0004789]| increased circulating aspartate transaminase level [MP:0005343]| increased circulating bilirubin level [MP:0005344]| abnormal bile salt homeostasis [MP:0005365]| increased sensitivity to induced morbidity/mortality [MP:0009763]| increased susceptibility to weight loss [MP:0010180]| increased or absent threshold for auditory brainstem response [MP:0011967] | Atp8b1 | 036309-UCD | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:20126555 PMID:18466903 |
MMRRC_36309-UCD, MMRRC_036309, MMRRC_3639 | 2026-07-25 09:42:04 | 0 | |||
|
NOD.Cg-Ifngtm1Ts H2h4/HbmMmmh Resource Report Resource Website 1+ mentions Issue |
RRID:MMRRC_037140-MU | Mus musculus | Research areas: Immunology and Inflammation; Mutation Type: Targeted Mutation ; Collection: Mullen | increased leukocyte cell number [MP:0000218]| increased monocyte cell number [MP:0000220]| extramedullary hematopoiesis [MP:0000240]| increased granulocyte number [MP:0000322]| abnormal spleen morphology [MP:0000689]| enlarged spleen [MP:0000691]| abnormal lymph node size [MP:0000701]| enlarged lymph nodes [MP:0000702]| increased body weight [MP:0001260]| decreased body weight [MP:0001262]| increased metastatic potential [MP:0001272]| abnormal response to new environment [MP:0001413]| altered susceptibility to infection [MP:0001793]| abnormal humoral immune response [MP:0001800]| decreased IgG level [MP:0001805]| decreased IgM level [MP:0001806]| decreased IgA level [MP:0001807]| abnormal inflammatory response [MP:0001845]| increased inflammatory response [MP:0001846]| brain inflammation [MP:0001847]| kidney inflammation [MP:0001859]| liver inflammation [MP:0001860]| lung inflammation [MP:0001861]| stomach inflammation [MP:0001873]| decreased inflammatory response [MP:0001876]| abnormal lactation [MP:0001882]| mammary gland alveolar hyperplasia [MP:0001884]| decreased litter size [MP:0001935]| abnormal lung volume [MP:0001942]| increased airway responsiveness [MP:0001952]| emphysema [MP:0001958]| increased B cell derived lymphoma incidence [MP:0002023]| increased T cell derived lymphoma incidence [MP:0002024]| increased lung adenocarcinoma incidence [MP:0002027]| increased sarcoma incidence [MP:0002032]| increased carcinoma incidence [MP:0002038]| increased pituitary adenoma incidence [MP:0002041]| decreased tumor incidence [MP:0002052]| premature death [MP:0002083]| abnormal spleen size [MP:0002224]| abnormal pulmonary alveolus morphology [MP:0002270]| decreased airway responsiveness [MP:0002335]| abnormal lymph node cortex morphology [MP:0002343]| abnormal lymph node primary follicle morphology [MP:0002345]| abnormal lymph node secondary follicle morphology [MP:0002346]| abnormal spleen red pulp morphology [MP:0002356]| abnormal spleen white pulp morphology [MP:0002357]| abnormal dendritic cell physiology [MP:0002376]| increased susceptibility to bacterial infection [MP:0002412]| increased susceptibility to viral infection [MP:0002418]| abnormal adaptive immunity [MP:0002420]| altered susceptibility to autoimmune disorder [MP:0002425]| abnormal macrophage physiology [MP:0002451]| abnormal dendritic cell antigen presentation [MP:0002455]| abnormal B cell physiology [MP:0002459]| decreased immunoglobulin level [MP:0002460]| increased immunoglobulin level [MP:0002461]| abnormal immunoglobulin level [MP:0002490]| decreased IgE level [MP:0002492]| increased IgE level [MP:0002497]| abnormal type IV hypersensitivity reaction [MP:0002534]| glomerulonephritis [MP:0002743]| decreased vertical activity [MP:0002757]| albuminuria [MP:0002871]| increased circulating alanine transaminase level [MP:0002941]| abnormal cytokine secretion [MP:0003009]| abnormal redox activity [MP:0003186]| small intestinal inflammation [MP:0003306]| abnormal tumor morphology [MP:0003448]| increased fear-related response [MP:0003459]| abnormal pancreatic beta cell physiology [MP:0003562]| increased ovarian carcinoma incidence [MP:0003579]| increased autoantibody level [MP:0003725]| decreased autoantibody level [MP:0003726]| abnormal nitric oxide homeostasis [MP:0003957]| abnormal lung vasculature morphology [MP:0004007]| abnormal maternal decidual layer morphology [MP:0004256]| decreased length of allograft survival [MP:0004752]| decreased anti-nuclear antigen antibody level [MP:0004795]| decreased anti-double stranded DNA antibody level [MP:0004798]| increased susceptibility to experimental autoimmune encephalomyelitis [MP:0004799]| decreased susceptibility to systemic lupus erythematosus [MP:0004802]| decreased susceptibility to autoimmune diabetes [MP:0004804]| abnormal immune tolerance [MP:0005000]| increased eosinophil cell number [MP:0005011]| increased lymphocyte cell number [MP:0005013]| increased T cell number [MP:0005015]| abnormal response to infection [MP:0005025]| decreased susceptibility to parasitic infection [MP:0005026]| increased susceptibility to parasitic infection [MP:0005027]| abnormal MHC II cell surface expression on macrophages [MP:0005040]| impaired natural killer cell mediated cytotoxicity [MP:0005070]| abnormal cytotoxic T cell physiology [MP:0005078]| decreased double-negative T cell number [MP:0005089]| cachexia [MP:0005150]| abnormal response to injury [MP:0005164]| decreased susceptibility to injury [MP:0005166]| abnormal renal glomerulus morphology [MP:0005325]| atherosclerotic lesions [MP:0005338]| decreased susceptibility to autoimmune disorder [MP:0005351]| abnormal Langerhans cell physiology [MP:0005362]| increased susceptibility to fungal infection [MP:0005399]| abnormal skin physiology [MP:0005501]| corneal vascularization [MP:0005542]| decreased circulating creatinine level [MP:0005554]| increased blood urea nitrogen level [MP:0005565]| decreased susceptibility to type IV hypersensitivity reaction [MP:0005616]| increased susceptibility to type IV hypersensitivity reaction [MP:0005617]| abnormal response to transplant [MP:0005671]| abnormal mammary gland growth during pregnancy [MP:0006269]| increased NK T cell number [MP:0008039]| abnormal uterine NK cell morphology [MP:0008054]| increased CD4-positive [MP:0008074]| alpha beta T cell number [MP:0008078]| increased CD8-positive [MP:0008135]| alpha-beta T cell number [MP:0008466]| small Peyer's patches [MP:0008474]| enlarged mesenteric lymph nodes [MP:0008496]| absent spleen germinal center [MP:0008497]| decreased IgG2a level [MP:0008498]| decreased IgG2b level [MP:0008499]| decreased IgG3 level [MP:0008523]| increased IgG1 level [MP:0008567]| absent lymph node germinal center [MP:0008596]| decreased interferon-gamma secretion [MP:0008660]| increased circulating interleukin-6 level [MP:0008661]| increased interleukin-10 secretion [MP:0008663]| decreased interleukin-10 secretion [MP:0008681]| increased interleukin-12 secretion [MP:0008687]| increased interleukin-17 secretion [MP:0008699]| increased interleukin-2 secretion [MP:0008702]| increased interleukin-4 secretion [MP:0008713]| increased interleukin-5 secretion [MP:0008770]| abnormal cytokine level [MP:0008828]| decreased survivor rate [MP:0008874]| abnormal lymph node cell ratio [MP:0009099]| decreased physiological sensitivity to xenobiotic [MP:0009246]| abnormal uterine NK cell physiology [MP:0009336]| pale spleen [MP:0009394]| increased splenocyte proliferation [MP:0009419]| increased uterine NK cell number [MP:0009643]| skeletal muscle fibrosis [MP:0009763]| abnormal urine homeostasis [MP:0009766]| increased sensitivity to induced morbidity/mortality [MP:0009788]| increased sensitivity to xenobiotic induced morbidity/mortality [MP:0009791]| increased susceptibility to bacterial infection induced morbidity/mortality [MP:0009828]| increased susceptibility to viral infection induced morbidity/mortality [MP:0010210]| increased tumor latency [MP:0010308]| abnormal circulating cytokine level [MP:0010574]| decreased tumor latency [MP:0010639]| aorta dilation [MP:0010659]| altered tumor pathology [MP:0010740]| abdominal aorta aneurysm [MP:0010750]| abnormal dendritic cell chemotaxis [MP:0010751]| increased susceptibility to parasitic infection induced morbidity/mortality [MP:0010760]| decreased susceptibility to parasitic infection induced morbidity/mortality [MP:0010766]| abnormal macrophage chemotaxis [MP:0011086]| abnormal NK cell physiology [MP:0011320]| postnatal lethality [MP:0011427]| incomplete penetrance [MP:0012431]| abnormal glomerular capillary morphology [MP:0013239]| mesangial cell hyperplasia [MP:0013590]| increased lymphoma incidence [MP:0030466]| abnormal cytokine secretion [MP:0003009]| thyroid inflammation [MP:0003504]| insulitis [MP:0004031]| decreased susceptibility to autoimmune diabetes [MP:0004804]| periinsulitis [MP:0005580]| decreased physiological sensitivity to xenobiotic [MP:0008874] | Ifng | 037140-MU | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:16394017 PMID:21220693 PMID:22119715 PMID:23509363 PMID:25400914 PMID:12244202 |
MMRRC_37140-MU, MMRRC_037140, MMRRC_3714 | 2026-07-25 09:42:11 | 2 | |||
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NOD.Cg-Pdcd1tm1.1Shr Ifngtm1Ts H2h4/HbmMmmh Resource Report Resource Website 1+ mentions Issue |
RRID:MMRRC_037145-MU | Mus musculus | Research areas: Immunology and Inflammation; Mutation Type: Targeted Mutation ; Collection: Mullen | increased leukocyte cell number [MP:0000218]| increased monocyte cell number [MP:0000220]| extramedullary hematopoiesis [MP:0000240]| increased granulocyte number [MP:0000322]| abnormal spleen morphology [MP:0000689]| enlarged spleen [MP:0000691]| abnormal lymph node size [MP:0000701]| enlarged lymph nodes [MP:0000702]| increased body weight [MP:0001260]| decreased body weight [MP:0001262]| increased metastatic potential [MP:0001272]| abnormal response to new environment [MP:0001413]| altered susceptibility to infection [MP:0001793]| abnormal humoral immune response [MP:0001800]| decreased IgG level [MP:0001805]| decreased IgM level [MP:0001806]| decreased IgA level [MP:0001807]| abnormal inflammatory response [MP:0001845]| increased inflammatory response [MP:0001846]| brain inflammation [MP:0001847]| kidney inflammation [MP:0001859]| liver inflammation [MP:0001860]| lung inflammation [MP:0001861]| stomach inflammation [MP:0001873]| decreased inflammatory response [MP:0001876]| abnormal lactation [MP:0001882]| mammary gland alveolar hyperplasia [MP:0001884]| decreased litter size [MP:0001935]| abnormal lung volume [MP:0001942]| increased airway responsiveness [MP:0001952]| emphysema [MP:0001958]| increased B cell derived lymphoma incidence [MP:0002023]| increased T cell derived lymphoma incidence [MP:0002024]| increased lung adenocarcinoma incidence [MP:0002027]| increased sarcoma incidence [MP:0002032]| increased carcinoma incidence [MP:0002038]| increased pituitary adenoma incidence [MP:0002041]| decreased tumor incidence [MP:0002052]| premature death [MP:0002083]| abnormal spleen size [MP:0002224]| abnormal pulmonary alveolus morphology [MP:0002270]| decreased airway responsiveness [MP:0002335]| abnormal lymph node cortex morphology [MP:0002343]| abnormal lymph node primary follicle morphology [MP:0002345]| abnormal lymph node secondary follicle morphology [MP:0002346]| abnormal spleen red pulp morphology [MP:0002356]| abnormal spleen white pulp morphology [MP:0002357]| abnormal dendritic cell physiology [MP:0002376]| increased susceptibility to bacterial infection [MP:0002412]| increased susceptibility to viral infection [MP:0002418]| abnormal adaptive immunity [MP:0002420]| altered susceptibility to autoimmune disorder [MP:0002425]| abnormal macrophage physiology [MP:0002451]| abnormal dendritic cell antigen presentation [MP:0002455]| abnormal B cell physiology [MP:0002459]| decreased immunoglobulin level [MP:0002460]| increased immunoglobulin level [MP:0002461]| abnormal immunoglobulin level [MP:0002490]| decreased IgE level [MP:0002492]| increased IgE level [MP:0002497]| abnormal type IV hypersensitivity reaction [MP:0002534]| glomerulonephritis [MP:0002743]| decreased vertical activity [MP:0002757]| albuminuria [MP:0002871]| increased circulating alanine transaminase level [MP:0002941]| abnormal cytokine secretion [MP:0003009]| abnormal redox activity [MP:0003186]| small intestinal inflammation [MP:0003306]| abnormal tumor morphology [MP:0003448]| increased fear-related response [MP:0003459]| abnormal pancreatic beta cell physiology [MP:0003562]| increased ovarian carcinoma incidence [MP:0003579]| increased autoantibody level [MP:0003725]| decreased autoantibody level [MP:0003726]| abnormal nitric oxide homeostasis [MP:0003957]| abnormal lung vasculature morphology [MP:0004007]| abnormal maternal decidual layer morphology [MP:0004256]| decreased length of allograft survival [MP:0004752]| decreased anti-nuclear antigen antibody level [MP:0004795]| decreased anti-double stranded DNA antibody level [MP:0004798]| increased susceptibility to experimental autoimmune encephalomyelitis [MP:0004799]| decreased susceptibility to systemic lupus erythematosus [MP:0004802]| decreased susceptibility to autoimmune diabetes [MP:0004804]| abnormal immune tolerance [MP:0005000]| increased eosinophil cell number [MP:0005011]| increased lymphocyte cell number [MP:0005013]| increased T cell number [MP:0005015]| abnormal response to infection [MP:0005025]| decreased susceptibility to parasitic infection [MP:0005026]| increased susceptibility to parasitic infection [MP:0005027]| abnormal MHC II cell surface expression on macrophages [MP:0005040]| impaired natural killer cell mediated cytotoxicity [MP:0005070]| abnormal cytotoxic T cell physiology [MP:0005078]| decreased double-negative T cell number [MP:0005089]| cachexia [MP:0005150]| abnormal response to injury [MP:0005164]| decreased susceptibility to injury [MP:0005166]| abnormal renal glomerulus morphology [MP:0005325]| atherosclerotic lesions [MP:0005338]| decreased susceptibility to autoimmune disorder [MP:0005351]| abnormal Langerhans cell physiology [MP:0005362]| increased susceptibility to fungal infection [MP:0005399]| abnormal skin physiology [MP:0005501]| corneal vascularization [MP:0005542]| decreased circulating creatinine level [MP:0005554]| increased blood urea nitrogen level [MP:0005565]| decreased susceptibility to type IV hypersensitivity reaction [MP:0005616]| increased susceptibility to type IV hypersensitivity reaction [MP:0005617]| abnormal response to transplant [MP:0005671]| abnormal mammary gland growth during pregnancy [MP:0006269]| increased NK T cell number [MP:0008039]| abnormal uterine NK cell morphology [MP:0008054]| increased CD4-positive [MP:0008074]| alpha beta T cell number [MP:0008078]| increased CD8-positive [MP:0008135]| alpha-beta T cell number [MP:0008466]| small Peyer's patches [MP:0008474]| enlarged mesenteric lymph nodes [MP:0008496]| absent spleen germinal center [MP:0008497]| decreased IgG2a level [MP:0008498]| decreased IgG2b level [MP:0008499]| decreased IgG3 level [MP:0008523]| increased IgG1 level [MP:0008567]| absent lymph node germinal center [MP:0008596]| decreased interferon-gamma secretion [MP:0008660]| increased circulating interleukin-6 level [MP:0008661]| increased interleukin-10 secretion [MP:0008663]| decreased interleukin-10 secretion [MP:0008681]| increased interleukin-12 secretion [MP:0008687]| increased interleukin-17 secretion [MP:0008699]| increased interleukin-2 secretion [MP:0008702]| increased interleukin-4 secretion [MP:0008713]| increased interleukin-5 secretion [MP:0008770]| abnormal cytokine level [MP:0008828]| decreased survivor rate [MP:0008874]| abnormal lymph node cell ratio [MP:0009099]| decreased physiological sensitivity to xenobiotic [MP:0009246]| abnormal uterine NK cell physiology [MP:0009336]| pale spleen [MP:0009394]| increased splenocyte proliferation [MP:0009419]| increased uterine NK cell number [MP:0009643]| skeletal muscle fibrosis [MP:0009763]| abnormal urine homeostasis [MP:0009766]| increased sensitivity to induced morbidity/mortality [MP:0009788]| increased sensitivity to xenobiotic induced morbidity/mortality [MP:0009791]| increased susceptibility to bacterial infection induced morbidity/mortality [MP:0009828]| increased susceptibility to viral infection induced morbidity/mortality [MP:0010210]| increased tumor latency [MP:0010308]| abnormal circulating cytokine level [MP:0010574]| decreased tumor latency [MP:0010639]| aorta dilation [MP:0010659]| altered tumor pathology [MP:0010740]| abdominal aorta aneurysm [MP:0010750]| abnormal dendritic cell chemotaxis [MP:0010751]| increased susceptibility to parasitic infection induced morbidity/mortality [MP:0010760]| decreased susceptibility to parasitic infection induced morbidity/mortality [MP:0010766]| abnormal macrophage chemotaxis [MP:0011086]| abnormal NK cell physiology [MP:0011320]| postnatal lethality [MP:0011427]| incomplete penetrance [MP:0012431]| abnormal glomerular capillary morphology [MP:0013239]| mesangial cell hyperplasia [MP:0013590]| increased lymphoma incidence [MP:0030466]| abnormal cytokine secretion [MP:0003009]| thyroid inflammation [MP:0003504]| insulitis [MP:0004031]| decreased susceptibility to autoimmune diabetes [MP:0004804]| periinsulitis [MP:0005580]| decreased physiological sensitivity to xenobiotic [MP:0008874]| vasculitis [MP:0001864]| pancreas inflammation [MP:0001869]| increased retinal ganglion cell number [MP:0002983]| insulitis [MP:0004031]| increased susceptibility to autoimmune diabetes [MP:0004803]| increased regulatory T cell number [MP:0004973]| decreased B-1 B cell number [MP:0004978]| abnormal immune tolerance [MP:0005000]| decreased T cell proliferation [MP:0005095]| increased T cell proliferation [MP:0005348] | |Pdcd1||Ifng|| | 037145-MU | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | MMRRC_37145-MU, MMRRC_037145, MMRRC_37145 | 2026-07-25 09:42:11 | 1 |
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