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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
Issue
https://www.jax.org/strain/030547
Source Database: JAX Mice and Services
Genetic Background:
Affected Genes: beta-2 microglobulin|interleukin 2 receptor; gamma chain|protein kinase; DNA activated; catalytic polypeptide|histocompatibility-2; MHC
Genomic Alteration: targeted mutation 1; University of North Carolina|targeted mutation 1; Warren J Leonard|severe combined immunodeficiency|targeted deletion; H2 complex
Availability: sperm
References:
Synonyms: NSG-B2M
Alternate IDs:
Notes: gene symbol note: beta-2 microglobulin|interleukin 2 receptor; gamma chain|protein kinase; DNA activated; catalytic polypeptide|histocompatibility-2; MHC; mutant strain|congenic strain: B2m|Il2rg|Prkdc|H2
Proper citation: RRID:IMSR_JAX:030547 Copy
Issue
https://www.jax.org/strain/030894
Source Database: JAX Mice and Services
Genetic Background:
Affected Genes: C-C motif chemokine receptor 5|apolipoprotein E
Genomic Alteration: targeted mutation 1; Bruno Luckow|targeted mutation 1; University of North Carolina
Availability: sperm
References:
Synonyms:
Alternate IDs:
Notes: gene symbol note: C-C motif chemokine receptor 5|apolipoprotein E; mutant strain|congenic strain: Ccr5|Apoe
Proper citation: RRID:IMSR_JAX:030894 Copy
Issue
https://www.jax.org/strain/030895
Source Database: JAX Mice and Services
Genetic Background:
Affected Genes: apolipoprotein E|C-C motif chemokine receptor 1|C-C motif chemokine receptor 5
Genomic Alteration: targeted mutation 1; University of North Carolina|targeted mutation 1; Ji-Liang Gao|targeted mutation 1; Bruno Luckow
Availability: sperm
References:
Synonyms:
Alternate IDs:
Notes: gene symbol note: apolipoprotein E|C-C motif chemokine receptor 1|C-C motif chemokine receptor 5; mutant strain|congenic strain: Apoe|Ccr1|Ccr5
Proper citation: RRID:IMSR_JAX:030895 Copy
Issue
https://www.jax.org/strain/030891
Source Database: JAX Mice and Services
Genetic Background:
Affected Genes: apolipoprotein E
Genomic Alteration: targeted mutation 1; University of North Carolina
Availability: sperm
References:
Synonyms:
Alternate IDs:
Notes: gene symbol note: apolipoprotein E; mutant strain|congenic strain: Apoe
Proper citation: RRID:IMSR_JAX:030891 Copy
Issue
https://www.jax.org/strain/027411
Source Database: JAX Mice and Services
Genetic Background:
Affected Genes: huntingtin
Genomic Alteration: targeted mutation 2; Marcy E MacDonald
Availability: sperm
References:
Synonyms:
Alternate IDs:
Notes: gene symbol note: huntingtin; mutant strain|congenic strain: Htt
Proper citation: RRID:IMSR_JAX:027411 Copy
Issue
https://www.jax.org/strain/029218
Source Database: JAX Mice and Services
Genetic Background:
Affected Genes: phenylalanine hydroxylase
Genomic Alteration: phenylalanine hydroxylase enu 2
Availability: live
References:
Synonyms:
Alternate IDs:
Notes: gene symbol note: phenylalanine hydroxylase; mutant strain|congenic strain: Pah
Proper citation: RRID:IMSR_JAX:029218 Copy
Issue
https://www.jax.org/strain/032435
Source Database: JAX Mice and Services
Genetic Background:
Affected Genes: transformation related protein 53|Kras proto-oncogene; GTPase
Genomic Alteration: targeted mutation 1; Anton Berns|targeted mutation 4; Tyler Jacks
Availability: live
References:
Synonyms:
Alternate IDs:
Notes: gene symbol note: transformation related protein 53|Kras proto-oncogene; GTPase; mutant strain|congenic strain: Trp53|Kras
Proper citation: RRID:IMSR_JAX:032435 Copy
Issue
https://www.jax.org/strain/033964
Source Database: JAX Mice and Services
Genetic Background:
Affected Genes: phosphatase and tensin homolog|Kras proto-oncogene; GTPase|Cre recombinase and estrogen receptor 1 fusion gene|pancreas specific transcription factor; 1a
Genomic Alteration: targeted mutation 1; Hong Wu|targeted mutation 4; Tyler Jacks|targeted mutation 2; Christopher VE Wright
Availability: live
References:
Synonyms: KPP
Alternate IDs:
Notes: gene symbol note: phosphatase and tensin homolog|Kras proto-oncogene; GTPase|Cre recombinase and estrogen receptor 1 fusion gene|pancreas specific transcription factor; 1a; mutant strain|congenic strain: Pten|Kras|cre/Esr1|Ptf1a
Proper citation: RRID:IMSR_JAX:033964 Copy
Issue Issue
https://www.jax.org/strain/018122
Source Database: JAX Mice and Services
Genetic Background:
Affected Genes: prion protein
Genomic Alteration: targeted mutation 1; Charles Weissmann
Availability: sperm
References:
Synonyms:
Alternate IDs:
Notes: gene symbol note: prion protein; mutant strain|congenic strain: Prnp
Proper citation: RRID:IMSR_JAX:018122 Copy
Issue
https://www.jax.org/strain/019103
Source Database: JAX Mice and Services
Genetic Background:
Affected Genes: nestin|transgene insertion 1; Rudiger Klein|
Genomic Alteration: transgene insertion 1; Rudiger Klein
Availability: sperm
References:
Synonyms:
Alternate IDs:
Notes: gene symbol note: nestin|transgene insertion 1; Rudiger Klein|; mutant strain|congenic strain: Nes|Tg(Nes-cre)1Kln|
Proper citation: RRID:IMSR_JAX:019103 Copy
Issue
https://www.jax.org/strain/018972
Source Database: JAX Mice and Services
Genetic Background:
Affected Genes: |myosin; heavy polypeptide 6; cardiac muscle; alpha|transgene insertion 2182; Michael D Schneider
Genomic Alteration: transgene insertion 2182; Michael D Schneider
Availability: sperm
References:
Synonyms:
Alternate IDs:
Notes: gene symbol note: |myosin; heavy polypeptide 6; cardiac muscle; alpha|transgene insertion 2182; Michael D Schneider; mutant strain|congenic strain: |Myh6|Tg(Myh6-cre)2182Mds
Proper citation: RRID:IMSR_JAX:018972 Copy
Issue
https://www.jax.org/strain/021479
Source Database: JAX Mice and Services
Genetic Background:
Affected Genes: cadherin related 23 (otocadherin)|modifier of age related hearing loss
Genomic Alteration: wild-type of age related hearing loss|129S1/SvImJ
Availability: sperm
References:
Synonyms:
Alternate IDs:
Notes: gene symbol note: cadherin related 23 (otocadherin)|modifier of age related hearing loss; mutant strain|congenic strain: Cdh23|Mahl
Proper citation: RRID:IMSR_JAX:021479 Copy
Issue
https://www.jax.org/strain/021568
Source Database: JAX Mice and Services
Genetic Background:
Affected Genes: interleukin 21 receptor|accelerated autoimmunity and lymphoproliferation transposition
Genomic Alteration: targeted mutation 1; Warren J Leonard|accelerated autoimmunity and lymphoproliferation
Availability: embryo
References:
Synonyms: BXSB.Yaa Il21r-/-. BXSB.Yaa IL-21R-/-
Alternate IDs:
Notes: gene symbol note: interleukin 21 receptor|accelerated autoimmunity and lymphoproliferation transposition; mutant strain|congenic strain: Il21r|Yaa
Proper citation: RRID:IMSR_JAX:021568 Copy
Issue Issue
https://www.jax.org/strain/021871
Source Database: JAX Mice and Services
Genetic Background:
Affected Genes: immunoglobulin heavy constant mu
Genomic Alteration: targeted mutation 1; University of Cologne
Availability: embryo
References:
Synonyms: BXSB.Cmu-. BXSB.muMT-. BXSB.Ighm-/-. Ighm-deficient BXSB.Yaa. BXSB.Yaa Ighm-/-. BXSB.IgM-. BXSB.Ighm null
Alternate IDs:
Notes: gene symbol note: immunoglobulin heavy constant mu; mutant strain|congenic strain: Ighm
Proper citation: RRID:IMSR_JAX:021871 Copy
Issue
https://www.jax.org/strain/022760
Source Database: JAX Mice and Services
Genetic Background:
Affected Genes: Fas cell surface death receptor|nitric oxide synthase 3; endothelial cell
Genomic Alteration: lymphoproliferation|targeted mutation 1; University of North Carolina
Availability: sperm
References:
Synonyms:
Alternate IDs:
Notes: gene symbol note: Fas cell surface death receptor|nitric oxide synthase 3; endothelial cell; mutant strain|congenic strain: Fas|Nos3
Proper citation: RRID:IMSR_JAX:022760 Copy
Issue Issue
https://www.jax.org/strain/024314
Source Database: JAX Mice and Services
Genetic Background:
Affected Genes: tumor necrosis factor receptor superfamily; member 1a|tumor necrosis factor receptor superfamily; member 1b
Genomic Alteration: targeted mutation 1; Immunex Research and Development Corporation
Availability: sperm
References:
Synonyms: NOD.TNFR1KO/TNFR2KO
Alternate IDs:
Notes: gene symbol note: tumor necrosis factor receptor superfamily; member 1a|tumor necrosis factor receptor superfamily; member 1b; mutant strain|congenic strain: Tnfrsf1a|Tnfrsf1b
Proper citation: RRID:IMSR_JAX:024314 Copy
Issue
https://www.jax.org/strain/024476
Source Database: JAX Mice and Services
Genetic Background:
Affected Genes: T cell receptor alpha chain|transgene insertion 1; Christophe Benoist|interferon gamma receptor 1|signal transducer and activator of transcription 4|thymus cell antigen 1; theta|T cell receptor beta chain
Genomic Alteration: transgene insertion 1; Christophe Benoist|targeted mutation 1; Michel Aguet|targeted mutation 1; Michael J Grusby|a variant
Availability: embryo
References:
Synonyms:
Alternate IDs:
Notes: gene symbol note: T cell receptor alpha chain|transgene insertion 1; Christophe Benoist|interferon gamma receptor 1|signal transducer and activator of transcription 4|thymus cell antigen 1; theta|T cell receptor beta chain; mutant strain|congenic strain: Tcra|Tg(TcraBDC2.5;TcrbBDC2.5)1Doi|Ifngr1|Stat4|Thy1|Tcrb
Proper citation: RRID:IMSR_JAX:024476 Copy
Issue
http://www.taconic.com/transgenic-mouse-model/abb-knockouttransgenic-hla-dr4
Source Database: Taconic Biosciences
Genetic Background:
Affected Genes: histocompatibility 2; class II antigen A; beta 1
Genomic Alteration: targeted mutation 1; Michael J Grusby
Availability: live
References:
Synonyms:
Alternate IDs:
Notes: gene symbol note: histocompatibility 2; class II antigen A; beta 1; mutant strain|congenic strain: H2-Ab1
Proper citation: RRID:IMSR_TAC:4149 Copy
Issue
https://www.taconic.com/transgenic-mouse-model/apoe
Source Database: Taconic Biosciences
Genetic Background:
Affected Genes: |apolipoprotein E
Genomic Alteration: |targeted mutation 1; University of North Carolina
Availability: live
References:
Synonyms: Apoe (ApoE) CONSTITUTIVE KNOCK OUT - C57BL/6 Background. B6.129P2-Apoe
Alternate IDs:
Notes: gene symbol note: |apolipoprotein E; mutant strain|congenic strain: |Apoe
Proper citation: RRID:IMSR_TAC:APOE Copy
Issue
https://www.taconic.com/transgenic-mouse-model/hla-b7
Source Database: Taconic Biosciences
Genetic Background:
Affected Genes: beta-2 microglobulin|
Genomic Alteration: targeted mutation 1; University of North Carolina|transgene insertion 55; Hidde Ploegh
Availability: live
References:
Synonyms:
Alternate IDs:
Notes: gene symbol note: beta-2 microglobulin|; unclassified|mutant stock: B2m|
Proper citation: RRID:IMSR_TAC:9661 Copy
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