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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
http://www.wormbase.org/db/get?name=WBStrain00055711
Source Database: WormBase (WB)
Genetic Background:
Affected Genes:
Genomic Alteration:
Availability: unknown
References:
Synonyms: hpIs860.
Alternate IDs:
Notes: hpIs860 [twk-40p(short)::eGFP + myo-2p::wCherry]. Cytosolic GFP expression in AVA, AVE & AVB in the head, with the strongest signal in AVA. Additional fluorescent signal in RVG (SAB) and tail (DVA).
Proper citation: RRID:WB-STRAIN:WBStrain00055711 Copy
http://www.wormbase.org/db/get?name=WBStrain00055677
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00019544(miro-1)|WBGene00022516(mtx-2)
Genomic Alteration: WBGene00019544(miro-1), WBGene00022516(mtx-2)
Availability: unknown
References:
Synonyms: mtx-2(wy50266) III; miro-1(wy50180) IV; oyIs14 V.
Alternate IDs:
Notes: oyIs14 [sra-6p::GFP + lin-15(+)]. Disrupted mitochondrial trafficking. Reference: Ding C, et al. Elife. 2022 Mar 14;11:e73557. PMID: 35285800.
Proper citation: RRID:WB-STRAIN:WBStrain00055677 Copy
http://www.wormbase.org/db/get?name=WBStrain00055710
Source Database: WormBase (WB)
Genetic Background:
Affected Genes:
Genomic Alteration:
Availability: unknown
References:
Synonyms: hpIs758; hpIs814.
Alternate IDs:
Notes: hpIs758 [rig-3p::LoxP::eBFP::LoxP::Chrimson::wCherry + twk-40p(short)::Cre + myo-2p::wCherry]. hpIs814 [flp-18p::LoxP::eBFP::Stop::LoxP::TeTx::wCherry + twk-40p(short)::Cre]. RFP positive in AVA soma and neurite along the VNC. Weak pharyngeal RFP. Flat and slow movement without ATR or LED stimulation. Chrimson activation induces loopy reversal but not loopy forward after 5min.
Proper citation: RRID:WB-STRAIN:WBStrain00055710 Copy
http://www.wormbase.org/db/get?name=WBStrain00055713
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00006691(twk-40)
Genomic Alteration: WBGene00006691(twk-40)
Availability: unknown
References:
Synonyms: twk-40(hp834) III; hpIs860.
Alternate IDs:
Notes: hpIs860 [twk-40p(short)::eGFP + myo-2p::wCherry]. Loopy movement with increased reversals. Cytosolic GFP expression in AVA, AVE & AVB in the head, with the strongest signal in AVA. Additional fluorescent signal in RVG (SAB) and tail (DVA).
Proper citation: RRID:WB-STRAIN:WBStrain00055713 Copy
http://www.wormbase.org/db/get?name=WBStrain00055679
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00004010(pha-1)
Genomic Alteration: WBGene00004010(pha-1)
Availability: unknown
References:
Synonyms: pha-1(e2123) III; wpEx517.
Alternate IDs:
Notes: Made_by: Manasa Basavaraju in the Hammarlund lab|"wpEx517 [srab-20p::Neptune2.5 + pha-1(+)]. Maintain at 25C to select for animals carrying the array. Neptune2.5 expression in PHB neuron can be used to isolate PHB by FACS. Used by CeNGEN project for RNA-Seq (https:"
Proper citation: RRID:WB-STRAIN:WBStrain00055679 Copy
http://www.wormbase.org/db/get?name=WBStrain00055712
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00006691(twk-40)
Genomic Alteration: WBGene00006691(twk-40)
Availability: unknown
References:
Synonyms: twk-40(bln336) III; hpIs860.
Alternate IDs:
Notes: hpIs860 [twk-40p(short)::eGFP + myo-2p::wCherry]. twk-40 gain-of-function allele. Paralyzed, no backward movement upon head touch. Cytosolic GFP expression in AVA, AVE & AVB in the head, with the strongest signal in AVA. Additional fluorescent signal in RVG (SAB) and tail (DVA).
Proper citation: RRID:WB-STRAIN:WBStrain00055712 Copy
http://www.wormbase.org/db/get?name=WBStrain00055663
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00010622(hbs-1)
Genomic Alteration: WBGene00010622(hbs-1)
Availability: unknown
References:
Synonyms: hbs-1(srf730) I.
Alternate IDs:
Notes: Made_by: Parissa Monem|"srf730 is a 900bp deletion within hbs-1. Reference: Monem PC et al. PLOS Genet. 2023 Jan 10;19(1):e1010577. doi: 10.1371/journal.pgen.1010577. PMID: 36626369"
Proper citation: RRID:WB-STRAIN:WBStrain00055663 Copy
http://www.wormbase.org/db/get?name=WBStrain00055662
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00016888(znf-598)
Genomic Alteration: WBGene00016888(znf-598)
Availability: unknown
References:
Synonyms: znf-598(srf2119) II.
Alternate IDs:
Notes: Made_by: Parissa Monem|"srf2119 is a 965bp deletion within znf-598. Reference: Monem PC et al. PLOS Genet. 2023 Jan 10;19(1):e1010577. doi: 10.1371/journal.pgen.1010577. PMID: 36626369"
Proper citation: RRID:WB-STRAIN:WBStrain00055662 Copy
http://www.wormbase.org/db/get?name=WBStrain00055660
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00004479(rps-10)|WBGene00004489(rps-20)|WBGene00006789(unc-54)
Genomic Alteration: WBGene00004479(rps-10), WBGene00004489(rps-20), WBGene00006789(unc-54)
Availability: unknown
References:
Synonyms: rps-10(srf0825[K125R]) rps-20(srf1046[K6R+K9R]) unc-54(srf1004[unc-54::T2A::FLAG::rareArg12::GFP]) I.
Alternate IDs:
Notes: Made_by: Parissa Monem|"Nuclear body wall muscle GFP+."
Proper citation: RRID:WB-STRAIN:WBStrain00055660 Copy
http://www.wormbase.org/db/get?name=WBStrain00055704
Source Database: WormBase (WB)
Genetic Background:
Affected Genes:
Genomic Alteration:
Availability: unknown
References:
Synonyms: hpIs819; hpIs810.
Alternate IDs:
Notes: hpIs819 [twk-40p(short)::GCaMP::T2A::NLS::mNeptune + lin-15(+)]. hpIs810 [flp-18p::LoxP::eBFP::Stop::LoxP::TeTx::wCherry + twk-40p(short)::Cre]. Transgenic animals exhibit strong RFP signals in AVA soma and neurites; cytoplasmic GFP and RFP in AVA, AVE, AVB and some neurons in RVG and tail (DVA).
Proper citation: RRID:WB-STRAIN:WBStrain00055704 Copy
http://www.wormbase.org/db/get?name=WBStrain00055706
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00006691(twk-40)
Genomic Alteration: WBGene00006691(twk-40)
Availability: unknown
References:
Synonyms: twk-40(hp834) III; hpIs814.
Alternate IDs:
Notes: hpIs814 [flp-18p::LoxP::eBFP::Stop::LoxP::TeTx::wCherry + twk-40p(short)::Cre]. Red fluorescence in AVA. twk-40(hp834) is a loss-of-function allele. twk-40(hp834) itself is highly loopy and a weak backward coiler. The presence of hpIs814 in the background reduces body bending and speed compared to twk-40(hp834) alone.
Proper citation: RRID:WB-STRAIN:WBStrain00055706 Copy
http://www.wormbase.org/db/get?name=WBStrain00055666
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00004323(rde-1)|WBGene00015107(viro-2)
Genomic Alteration: WBGene00004323(rde-1), WBGene00015107(viro-2)
Availability: unknown
References:
Synonyms: viro-2(vir10) III; rde-1(ne219) V; jyIs8.
Alternate IDs:
Notes: jyIs8 [pals-5p::GFP + myo-2p::mCherry]. Orsay virus infection defect. Reference: Jiang H, et al. mBio. 2017 Sep 5;8(5):e00940-17. doi: 10.1128/mBio.00940-17. PMID: 28874467.
Proper citation: RRID:WB-STRAIN:WBStrain00055666 Copy
http://www.wormbase.org/db/get?name=WBStrain00055702
Source Database: WormBase (WB)
Genetic Background:
Affected Genes:
Genomic Alteration:
Availability: unknown
References:
Synonyms: ljIs131; hpEx4340.
Alternate IDs:
Notes: ljIs131 [myo-3p::GCaMP3::UrSL2::tagRFP-T]. hpEx4340 [nmr-1p::TeTx::wCherry + sra-11p::TeTx::wCherry + HygromycinR]. Animals carrying the array show additional red fluorescence in the head compared to those that have lost the array. Transgenic animals are severely Unc. RFP positive head neuron soma can be observed under V16 in older animals. Hygromycin can be used to select for hpEx4340 transgenic animals. Reference: Lu Y, et al. Curr Biol. 2022 Nov 7;32(21):4631-4644.e5. doi: 10.1016/j.cub.2022.09.002. PMID: 36182701.
Proper citation: RRID:WB-STRAIN:WBStrain00055702 Copy
http://www.wormbase.org/db/get?name=WBStrain00055701
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00023497(lin-15B)|WBGene00023498(lin-15A)
Genomic Alteration: WBGene00023497(lin-15B), WBGene00023498(lin-15A)
Availability: unknown
References:
Synonyms: lin-15B&lin-15A(n765) X; hpIs774; hpEx4292.
Alternate IDs:
Notes: hpIs774 [twk-40p(short)::GCaMP6s::mNeptune]. hpEx4292 [pdf-1p::LoxP::eBFP::LoxP::gtACR2::Cherry + twk-40p(short)::Cre + lin-15(+)]. Pick non-Muv to maintain. Red and green fluorescence in multiple head neurons. Activation of gtACR2 reduces AVB signals but does not generate specific changes in AVA.
Proper citation: RRID:WB-STRAIN:WBStrain00055701 Copy
http://www.wormbase.org/db/get?name=WBStrain00055709
Source Database: WormBase (WB)
Genetic Background:
Affected Genes:
Genomic Alteration:
Availability: unknown
References:
Synonyms: hpEx4362.
Alternate IDs:
Notes: hpEx4362 [flp-18p::cha-1(sense) + twk-40p::cha-1(antisense) + ttx-3p::GFP]. Pick animals with GFP expression in AIY to maintain. Transgenic animals exhibit reduced forward speed and body bending; this phenotype is not fully penetrate.
Proper citation: RRID:WB-STRAIN:WBStrain00055709 Copy
http://www.wormbase.org/db/get?name=WBStrain00055652
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00001834(hda-1)
Genomic Alteration: WBGene00001834(hda-1)
Availability: unknown
References:
Synonyms: hda-1(cw2) II.
Alternate IDs:
Notes: hda-1(cw2) mutants are viable as homozygotes, although many die as embryos or larvae. Severely uncoordinated with defective vulval development and reduced fertility. Reference: Zinovyeva AY, et al. Dev Biol. 2006 Jan 1;289(1):229-42. PMID: 16313898
Proper citation: RRID:WB-STRAIN:WBStrain00055652 Copy
http://www.wormbase.org/db/get?name=WBStrain00055651
Source Database: WormBase (WB)
Genetic Background:
Affected Genes:
Genomic Alteration:
Availability: unknown
References:
Synonyms: yfSi1 II.
Alternate IDs:
Notes: Made_by: Katja R Kasimatis|"yfSi1 [nspf-1p::nspf-1::6xHis::tbb-2 3' UTR + loxP, II:8420157]. C-terminal 6xHis-tagged NSPF-1 allows visualization of NSPF seminal fluid protein localization in males and hermaphrodites. Transgene inserted into ttTi5650 MosSCI site (II:8420157) using CRISPR/Cas9. Reference: Kasimatis KR, et al. (2022) No evidence of sexual conflict for a novel sperm-derived seminal fluid protein in Caenorhabditis nematodes. bioRxiv doi: https:"
Proper citation: RRID:WB-STRAIN:WBStrain00055651 Copy
http://www.wormbase.org/db/get?name=WBStrain00055650
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00003031(lin-46)
Genomic Alteration: WBGene00003031(lin-46)
Availability: unknown
References:
Synonyms: lin-46(ma398[lin-46::mCherry]) V.
Alternate IDs:
Notes: mCherry reporter inserted into C-terminus of endogenous lin-46 locus. Superficially wild-type. Fluorescent signal is very dim and bleaches very quickly. Reference: Ilbay O, et al. C. elegans LIN-28 controls temporal cell-fate progression by regulating LIN-46 expression via the 5UTR of lin-46 mRNA. bioRxiv 697490; doi: https:
Proper citation: RRID:WB-STRAIN:WBStrain00055650 Copy
http://www.wormbase.org/db/get?name=WBStrain00055659
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00004479(rps-10)
Genomic Alteration: WBGene00004479(rps-10)
Availability: unknown
References:
Synonyms: rps-10(srf1025[rps-10::3xHA]) I.
Alternate IDs:
Notes: 3xHA tag inserted at C-terminus of endogenous rps-10 locus. Some growth defects on its own, which can be exacerbated in conjunction with mutants of no-go mRNA decay factors. Reference: Monem PC et al. PLOS Genet. 2023 Jan 10;19(1):e1010577. doi: 10.1371/journal.pgen.1010577. PMID: 36626369|"Made_by: Parissa Monem"
Proper citation: RRID:WB-STRAIN:WBStrain00055659 Copy
http://www.wormbase.org/db/get?name=WBStrain00055656
Source Database: WormBase (WB)
Genetic Background:
Affected Genes:
Genomic Alteration:
Availability: unknown
References:
Synonyms: cwEx486.
Alternate IDs:
Notes: cwEx486 [mnp-1p::mnp-1::GFP + rol-6(su1006)]. Pick Rollers to maintain. Generated in N2 background.
Proper citation: RRID:WB-STRAIN:WBStrain00055656 Copy
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