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http://www.dkfz.de/en/epidemiologie-krebserkrankungen/software/software.html
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 24,2023. Software program that performs estimation of power and sample sizes required to detect genetic and environmental main, as well as gene-environment interaction (GxE) effects in indirect matched case-control studies (1:1 matching). When the hypothesis of GxE is tested, power/sample size will be estimated for the detection of GxE, as well as for the detection of genetic and environmental marginal effects. Furthermore, power estimation is implemented for the joint test of genetic marginal and GxE effects (Kraft P et al., 2007). Power and sample size estimations are based on Gauderman''s (2002) asymptotic approach for power and sample size estimations in direct studies of GxE. Hardy-Weinberg equilibrium and independence of genotypes and environmental exposures in the population are assumed. The estimates are based on genotypic codes (G=1 (G=0) for individuals who carry a (non-) risk genotype), which depend on the mode of inheritance (dominant, recessive, or multiplicative). A conditional logistic regression approach is used, which employs a likelihood-ratio test with respect to a biallelic candidate SNP, a binary environmental factor (E=1 (E=0) in (un)exposed individuals), and the interaction between these components. (entry from Genetic Analysis Software)
Proper citation: PIAGE (RRID:SCR_013124) Copy
http://galton.uchicago.edu/~junzhang/LAPSTRUCT.html
Software application to describe population structure using biomarker data ( typically SNPs, CNVs etc.) available in a population sample. The main features different from PCA are: (1) geometrically motivated and graphic model based; (2)robustness of outliers. (entry from Genetic Analysis Software)
Proper citation: LAPSTRUCT (RRID:SCR_007550) Copy
https://cran.r-project.org/web/packages/ibdreg/index.html
Software package in S-PLUS and R to test genetic linkage with covariates by regression methods with response IBD sharing for relative pairs. Account for correlations of IBD statistics and covariates for relative pairs within the same pedigree. (entry from Genetic Analysis Software)
Proper citation: IBDREG (RRID:SCR_013127) Copy
http://www003.upp.so-net.ne.jp/pub/publications.html#sl
Software application for inkage disequilibrium grouping of single nucleotide polymorphisms (SNPs) reflecting haplotype phylogeny for efficient selection of tag SNPs. (entry from Genetic Analysis Software)
Proper citation: LDGROUP (RRID:SCR_006282) Copy
http://www-gene.cimr.cam.ac.uk/clayton/software/
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 12,2023. Software application that tests for association between genetic marker and disease by examining the transmission of markers from parents to affected offspring. The main features which differ from other similar programs are: (1) It can deal with transmission of multi-locus haplotypes, even if phase is unknown, and (2) Parental genotypes may be unknown. (entry from Genetic Analysis Software)
Proper citation: TRANSMIT (RRID:SCR_007571) Copy
http://gaow.github.io/genetic-analysis-software/l/linkage---ceph/
Software application (entry from Genetic Analysis Software)
Proper citation: LINKAGE - CEPH (RRID:SCR_007048) Copy
http://compgen.rutgers.edu/multimap.shtml
Software program for automated construction of genetic maps (entry from Genetic Analysis Software)
Proper citation: MULTIMAP (RRID:SCR_007168) Copy
https://github.com/gaow/genetic-analysis-software/blob/master/pages/MAPMAKER%26SIBS.md
THIS RESOURCE IS NO LONGER IN SERVCE, documented September 22, 2016. Data analysis software for complete multipoint analysis.
Proper citation: MAPMAKER/SIBS (RRID:SCR_008012) Copy
http://www.stat.washington.edu/thompson/Genepi/MORGAN/Morgan.shtml
Software programs for segregation and linkage analysis, using a variety of Markov chain Monte Carlo (MCMC) methods. Includes MCMC methods for multilocus gene identity by descent (including homozygosity mapping) and Monte Carlo Lod scores. Also, other programs for EM analysis of quantitative traits.
Proper citation: MORGAN (RRID:SCR_006906) Copy
http://www.pierroton.inra.fr/genetics/labo/Software/Famoz/index.html
Software application that uses likelihood calculation and simulation to perform parentage studies with codominant, dominant, cytoplasmic markers or combinations of the different types (entry from Genetic Analysis Software)
Proper citation: FAMOZ (RRID:SCR_007477) Copy
http://www.mds.qmw.ac.uk/statgen/dcurtis/software.html
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 5th,2023. Software application that uses Monte Carlo method for assessing significance of a case-control association study with multi-allelic marker. (entry from Genetic Analysis Software).
Proper citation: CLUMP (RRID:SCR_007476) Copy
http://darwin.uvigo.es/software/treescan.html
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on January 11, 2023. Software application that is intended to provide p-values for the hypothesis of association between evolutionary clades and continuous traits, using haplotype trees. (entry from Genetic Analysis Software)
Proper citation: TREESCAN (RRID:SCR_007108) Copy
http://pngu.mgh.harvard.edu/purcell/whap/
THIS RESOURCE IS NO LONGER IN SERVICE, documented on July 24, 2015. This package is no longer supported. The majority of the functionality for conditional haplotype tests in population-based samples has been implemented in PLINK, with a better interface and more robust, faster computation: please use that from now on. Software tool to perform haplotype-based association analysis, for quantitative and qualitative traits, in population and family samples, using single nucleotide polymorphism or multiallelic marker data. What whap can do: * Analyze quantitative and qualitative traits * Handle unrelated individuals and/or parent-offspring trio data * Perform a regression-based haplotype association test for SNP data * Perform a secondary test based on pairwise haplotype similarity * Phase genotype data using a standard E-M approach, and handle ambiguity in E-M inferred haplotypes * Include covariates and moderator variables * Flexibly constrain effects across haplotypes to tested nested models * Perform a robust within-family test when parental genotypes are present * Analyze multiallelic markers (new) * Use dominant or recessive (new) genetic models (new)
Proper citation: Whap (RRID:SCR_007103) Copy
http://mga.bionet.nsc.ru/soft/mgamapf2/
Software application that map QTLs in F-2 intercross in model organisms (entry from Genetic Analysis Software)
Proper citation: MGA-MAPF2 (RRID:SCR_008108) Copy
http://www.uni-bonn.de/~umt70e/soft.htm
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 5th,2023. Software application for calculation of the restricted likelihood-ratio affected sib-pair test for linkage allowing for imprinting (entry from Genetic Analysis Software)
Proper citation: ILR (RRID:SCR_007895) Copy
http://csg.sph.umich.edu/boehnke/sibmed.php
Software application that identifies likely genotyping errors and mutations for a sib pair in the context of multipoint mapping. (entry from Genetic Analysis Software)
Proper citation: SIBMED (RRID:SCR_007495) Copy
http://www.mapmanager.org/mmQT.html
A graphic, interactive program to map quantitative trait loci by regression methods; MAP MANAGER CLASSIC enhanced by quantitative trait mapping. (entry from Genetic Analysis Software)
Proper citation: MAP MANAGER QT (RRID:SCR_008101) Copy
THIS RESOURCE IS NO LONGER IN SERVICE. Documented September 15, 2017. Software application (entry from Genetic Analysis Software)
Proper citation: S (RRID:SCR_007646) Copy
http://www.chgb.org.cn/lda/lda.htm
THIS RESOURCE IS NO LONGER IN SERVCE, documented September 22, 2016. A Java program for analyzing the pairwise linkage disequilibrium.
Proper citation: LDA (RRID:SCR_007527) Copy
http://genome.sph.umich.edu/wiki/RvTests
Software application (entry from Genetic Analysis Software)
Proper citation: RVTESTS (RRID:SCR_007639) Copy
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