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http://ctsaconnect.org/

THIS RESOURCE IS NO LONGER IS SERVICE. Documented on December 5th, 2022. Semantic framework to integrate information about research activities, clinical activities, and scientific resources to facilitate the production and consumption of Linked Open Data about investigators, physicians, biomedical research resources, services, and clinical activities. The goal is to enable software to consume data from multiple sources and allow the broadest possible representation of researchers'''' and clinicians'''' activities and research products. Current research tracking and networking systems rely largely on publications, but clinical encounters, reagents, techniques, specimens, model organisms, etc., are equally valuable for representing expertise. CTSAConnect will provide linkage between semantic representations of a wide range of clinical and research data using controlled vocabularies mapped to the Unified Medical Language System (UMLS) as a bridge between the two subject areas. The data sources include data from Medicaid, hospital billing systems, CTSAShareCenter, and other CTSA resource data, eagle-i and VIVO. It allows institutions to leverage existing tools and data sources by making the information they contain more discoverable and easier to integrate. For instance, with the ISF, researchers can be characterized by organizational affiliations, grant and project participation, research resources that they have generated, and publications that they have (co)-authored. Clinicians can be characterized by training and credentials, by clinical research topic, and by the kinds of procedures and specialization that can be inferred from encounter data. LOD refers to data that has been given a specific Uniform Resource Identifier (URI), for the purpose of sharing and linking data and information on the Semantic Web. While a large amount of data is published as LOD, there remains a significant gap in the representation of research resources and clinical expertise. Researchers can be characterized by the organization to which they belong, the grants and research in which they have participated, the research topics and research resources (reagents, biospecimens, animal models) they have generated, as well as the publications they have (co)-authored. Clinician profiles on the other hand, can be defined by their credentials, clinical research topics, and the kinds of procedures and specialization that can be inferred from clinical encounter data. They believe that integrating and relating this diversity of information sources and platforms requires addressing the overlap between research resources and the attributes and activities of researchers and clinicians. CTSAconnect aims to promote integration and discovery of research activities, resources, and clinical expertise. To this end, they will publish their ontologies and LOD via their website, which will also illustrate repeatable methods and examples of how to extract, consume, and utilize this valuable new LOD using freely available tools like VIVO, eagle-i, and Google APIs. CTSAconnect is a collaboration between Oregon Health & Science University, Stony Brook University, Cornell University, Harvard University, University at Buffalo, and the University of Florida, and leverages the work of eagle-i (eagle-i.net), VIVO (vivoweb.org), and ShareCenter (ctsasharecenter.org).

Proper citation: CTSAconnect (RRID:SCR_005225) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012e-58c7-d44f-55da-381e80000000

Core to provide gene expression data analysis service. Activities range from the provision of services to fully collaborative grant funded investigations.

Proper citation: Harvard Partners HealthCare Center for Personalized Genetic Medicine Bioinformatics Core Facility (RRID:SCR_000882) Copy   

•   Source: SciCrunch Registry

http://www.spl.harvard.edu/

A laboratory dedicated to advancing health care through utilizing computation and imaging to new areas of medicine.

Proper citation: BWH Surgical Planning Laboratory (RRID:SCR_000869) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012e-5e5d-69c2-55da-381e80000000

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 27, 2023. Core facility that provides the following services: Storage services for -80 degrees C and -190 degrees C in secure facility.

The Biospecimen Repository provides long-term storage of clinical and research material in -80 degrees C and liquid nitrogen freezers located at Dana Farber''s Harbor Campus. Transportation of samples to and from Harbor Campus is provided by the facility for a small fee. Competitive prices are available on per box or per freezer basis in both segregated or non-segregated environments.

Proper citation: DFCI Biospecimen Repository Core Facility (RRID:SCR_009747) Copy   

•   Source: SciCrunch Registry

http://www.ohsu.edu/xd/

As the state''s only health and research university, OHSU brings together patient care, research, education of the next generation of health care providers and scientists and community service to improve the health and well-being of all Oregonians.

Proper citation: Oregon Health and Science University; Oregon; USA (RRID:SCR_009665) Copy   

•   Source: SciCrunch Registry

http://utep.eagle-i.net/i/00000134-a952-c738-bfc0-fe9780000000

THIS RESOURCE IS NO LONGER IN SERVCE, documented January 23, 2019. Core facility that provides the following services: Zeiss LD-5 Pascal Scanning Confocal Microscope/Assisted access, Zeiss Axioskop Epifluorescence Microscope/Assisted access, Zeiss EM-10 Transmission Electron Microscope/Assisted access, Microscopy sample preparation, Observation and photography service. The Analytical Cytology Core Facility provides assistance in the designing of protocols and the use of sophisticated, well maintained and supervised equipment. Each microscope is equipped with software for image analysis, image processing and printing of digital images. Service contracts are maintained on each of the microscopes. Computers and software are regularly upgraded. Confocal workshops are held regularly to familiarize users with new techniques and new protocols. The specific aims of the Analytical Cytology Core Facility (ACCF) are: 1. to train users in the design of protocols, the fixations, sectioning, cryofixations, immunolocalizations, the use of the Zeiss EM-10, the Zeiss Axioskop epifluorescence microscope and the Zeiss Pascal scanning confocal microscope with image analysis and image processing, 2. to support new faculty in realizing their research objectives that utilize microscopy, 3. to support the productivity of the Infectious Diseases and Immunology unit, the Toxicology unit, the Neuroscience/Metabolic Disorders unit, the Statistical Consulting Laboratory and the Bioinformatics unit by assisting faculty, undergraduate, masters, doctoral and postdoctoral students in advancing biomedical research, 4. to maintain and upgrade equipment and expertise and; 5. to provide core services anticipating self-sustaining maintenance of the core facility.

Proper citation: University of Texas El Paso Analytical Cytology Core Facility (RRID:SCR_010137) Copy   

•   Source: SciCrunch Registry

http://cancer.dartmouth.edu/res/geospatial.html

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 23,2022. A resource to develop shared resources for the implementation of geospatial analysis for cancer research at Dartmouth. Their goal is to provide expert consultation and collaboration for research projects of NCCC members in behavior, epidemiology, and health services research. The GeoSpatial Resource also strives to educate members of the community in different aspects of geospatial analysis by providing courses through TDI and at Dartmouth College.

Proper citation: Dartmouth Geospatial Shared Resource (RRID:SCR_000874) Copy   

•   Source: SciCrunch Registry

https://www.ohsu.edu/transgenic-mouse-models-core

Core assists investigators with developing genetically engineered rodent models of human diseases for studying mutant genes and investigating molecular mechanisms underlying pathological processes.

Proper citation: OHSU Animal Model Support Core Facility (RRID:SCR_009994) Copy   

•   Source: SciCrunch Registry

http://ohsu.eagle-i.net/i/0000013d-d68a-722f-f60f-bfff80000000

THIS CORE IS NO LONGER IN SERVICE.Documented on December 6,2022. Core facility that provides the following services: Transmission electron microscopy. Imaging center has an excellent physical facility for handling samples for light or electron microscopy. We have a unique Multi-suite dissection, sectioning, and embedding area. This area is equipped with fume hood, two refrigerators, -80 freezer, tissue processors, and surgical instruments. Tissues of interest may be prepared ranging from fresh frozen for fluorescence microscopy to embedding in plastic for electron microscopy. We have or have access to; cryostats, paraffin microtomes, vibratomes, and ultramicrotomes. The EM core is experienced in many specialized electron microcopy techniques. These include immunogold labeling, negative staining. We have two FEI transmission electron microscopes, a Morgagni, and a Techni 12, both with AMT digital cameras for micrograph production.

Proper citation: OHSU Immuno Electron Microscopy Core (RRID:SCR_009979) Copy   

•   Source: SciCrunch Registry

http://ohsu.eagle-i.net/i/0000012a-24ff-653a-d994-629180000000

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on December 6,2022. Core facility that provides the following services: Confocal and epi-fluorescence imaging, Image processing and analysis, Stereology measurement service, Laser Capture Microdissection service, Live cell imaging service. The Imaging and Morphology Support Core of the ONPRC is designed to meet the imaging needs of ONPRC scientists and of the OHSU scientific community by providing state-of-the-art facilities, expertise, assistance and training in the use of advanced light microscopy, image analysis, processing and printing, and laser capture microdissection. Special emphasis is placed on quantitative evaluation of imaging experiments using both stereology and automated image analysis.

Proper citation: OHSU Imaging and Morphology Support Core Laboratory (RRID:SCR_009978) Copy   

•   Source: SciCrunch Registry

http://ohsu.eagle-i.net/i/0000012b-00cb-8534-79a3-373680000000

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on December 6,2022. Core facility that provides the following services: Sterols assay, Mevalonic acid assay. The OHSU Lipid Lab offers precise determination of lipids and specialized lipid metabolites not routinely available in general hospital clinical labs or elsewhere in Oregon. Currently, the OHSU Lipid Lab is the only laboratory on the West Coast that does sterols.

Proper citation: OHSU Lipid-Atherosclerosis Laboratory (RRID:SCR_009976) Copy   

•   Source: SciCrunch Registry

http://ohsu.eagle-i.net/i/0000012b-00c9-392d-79a3-373680000000

THIS RESOURCE IS NO LONGER IN SERVICE.Documented on December 6, 2022.Core facility that provides the following services: 17-hydroxyprogesterone (17a-P)-RIA, Androstenedioine (A4)-Ext-Chrom-RIA, b-Endorphin (bEP)-Iodination-RIA, Cholecystokinin (CCK)-Iodination-RIA, Corticosterone-Ext-RIA, Corticotropin-releasing factor (CRF)-Iodination-RIA, Dehydrocorticosterone (DOC)-Ext-RIA, Dihydrotestosterone (DHT)-Ext-Chrom-RIA, Estradiol-17b (E2)-Ext-RIA, Estradiol-17b (E2)-Ext-Chrom-RIA, Follicle-stimulating hormone (FSH)-Iodination-RIA, Gonadotropin-releasing hormone (GnRH)-Iodination-RIA, Growth hormone-releasing hormone (GHRH)-Iodination-RIA, Luteinizing hormone (LH)-Iodination-RIA, Neuropeptide Y (NPY)-Iodination-RIA, Progesterone (P4)-Ext-RIA, Progesterone (P4)-Ext-Chrom-RIA, 17-hydroxyprogesterone (17a-P)-Ext-Chrom-RIA, Testosterone (T)-Ext-RIA, Testosterone (T)-Ext-Chrom-RIA, Aldosterone-Active-RIA, Androstenedioine (A4)-CTC-RIA, Androstenedioine (A4)-Double-Antibody RIA, Corticosterone-RIA, Cortisol (17a-hydroxycorticosterone)-RIA, Cortisol (17a-hydroxycorticosterone)-ELISA, Dehydroepiandrosterone (DHEA)-ELISA, Dehydroepiandrosterone (DHEA)-RIA, Dexamethasone-ELISA, Dihydrotestosterone (DHT)-RIA, Estradiol-17b (E2)-Double-Antibody RIA, Estradiol-17b (E2)-Ultra-sensitive RIA, Estradiol-17b (E2)-Coat-the-Count RIA, Estradiol-17b (E2)-ELISA, Estrone (E1)-ELISA, Estrone (E1)-RIA, Free Testosterone (Free T)-Coat-the-count RIA, Free Testosteroine (Free T)-RIA, Glucagon-RIA, Insulin-RIA, Insulin-ELISA, Insulin (human)-RIA, Insulin (rat)-RIA, Insulin (sensitive rat)-RIA, Pregnenolone-EIA, Progesterone (P4)-RIA, Progesterone (P4) (17alpha-OH)-ELISA, Progesterone (P4)-EIA, Testosterone (T)-RIA, Testosterone (T)-EIA, Testosterone (T)-ELISA, Adiponectin (Rat)-ELISA, Adrenocorticotropins (ACTH)-RIA, Anti-Mullerian hormone-Active-ELISA, C-Peptide-RIA, Cotinine-ELISA, Cotinine (rat)-ELISA, C-reactive protein (CRP)-Ultra-sensitive ELISA, Cytokines, individual-ELISA, Dehydroepiandrosterone sulfate (DHEAS)-RIA, Delta-like 1 (DLK-1)-ELISA, Ethinyl estradiol (EE2)-Ext-RIA, Follicle-stimulating hormone (FSH)-RIA, Ghrelin (human)-RIA, Growth hormone (GH)-ELISA, Growth hormone (GH) (rat)-RIA, 5-Hydroxyindoleacetic acid (5-HIAA)-ELISA, Inhibin-a-ELISA, Inhibin-b-Active-ELISA, Insulin-like growth factor (IGF-1)-ELISA, Insulin-like growth factor (IGF-1) (mouse/rat)-ELISA, Leptin (mouse)-RIA, Leptin (primate)-RIA, Leptin (rat)-RIA, Levonorgestrel (LNG)-Ext-RIA, Low-density Lipoprotein (LDL)-EIA, Prolactin (rat)-ELISA, Prostate-specific antigen (PSA)-ELISA, Quantikine HS-High sensitivity ELISA, Serotonin (5-HT)-RIA, Serotonin (5-HT)-ELISA, Vasopressin-EIA-Extraction. The Endocrine Technology Support Core Lab (ETSL) has provided intra- and extramural investigators with analysis of protein and steroid content in blood, as well as in biological tissues and fluids for more than 3 decades. Principal support functions include provision of routine assays (for most naturally occurring steroid and protein hormones involved in the regulation of reproduction, metabolism, and the central nervous system) and development of new assays (e.g., Multiplex platforms for cytokines and signaling molecules).

Proper citation: OHSU Endocrine Technology Support Core Laboratory (RRID:SCR_009973) Copy   

•   Source: SciCrunch Registry

http://ohsu.eagle-i.net/i/0000012a-2500-0a1a-d994-629180000000

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on December 6,2022. Core facility that provides the following services: Equipment design and fabrication service, Computer interfacing service, Embedded processor design service, Circuit board design service, Research equipment consulting. The Electronics & Instrument Design Core Resource provides hands-on design and fabrication of specialized equipment for research projects. Projects involve analog and digital electronics design, microcontroller, software development and optical and embedded processor design. The core director, John Hunt, MSEE, is a senior research engineer and instructor in the Department of Biomedical Engineering, OHSU School of Medicine. OHSU School of Medicine. He has worked as a research engineer at OGI/OHSU since 1980 and has developed equipment for many research projects and departments.

Proper citation: OHSU Electronics and Instrumentation Design Core Resource (RRID:SCR_009971) Copy   

•   Source: SciCrunch Registry

http://upr.eagle-i.net/i/0000012b-00bf-e710-9e37-5ded80000000

These facilities contain three examination/study rooms, two gynecological examination rooms, two infusion rooms, one dental room, and one record room.

Proper citation: Puerto Rico Clinical and Translational Research Consortium Nursing Services (RRID:SCR_009970) Copy   

•   Source: SciCrunch Registry

http://ohsu.eagle-i.net/i/00000139-306b-819d-1eaf-424280000000

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on December 6, 2022. Core facility that provides the following services: Data storage planning, Database design and development, Website development. The BMISR provides expertise in data collection and management to clinical researchers. Through effective trial management and innovative data collection, clinical trial efficiency can be improved and high quality data collected for analysis. This automated data collection, storage and reporting reduce data errors and save time and effort during collection and analysis. Consultation and services are available during every stage of the research process--from grant proposal writing through research data collection, management and analysis. We can provide custom applications for data collection, management and dissemination using a broad array of technologies and tools. We can help with standalone database applications (such as Access), using scannable paper forms, developing web applications, designing database applications, just to name a few.

Proper citation: OHSU Biomedical Informatics Shared Resource (RRID:SCR_009966) Copy   

•   Source: SciCrunch Registry

https://www.ohsu.edu/lab-services/biochemical-genetics

Core facility that provides the following services: Amino acid analyses, Quantitative glycine analysis, Phytanic acid analysis, plasma, Succinylacetone with organic acids analysis, urine, Tay-Sachs carrier screening, serum, Very long chain fatty acid analysis, plasma, Quantitative alanine analysis, Aspartylglucosamine analysis, urine, Carnitine analysis, plasma, Cystathionine analysis, urine, Quantitiative cystine analysis, urine, Hexosaminidase A & B analysis, serum, Homocystine analysis, urine, Ketolytic enzyme testing, Leukocyte preparation, Mucopolysaccharide analysis, urine, Qualitative analysis of oligosaccharides, urine, Organic acids analysis, Quantitative analysis of phenylalanine, plasma, Phosphoethanoloamine analysis, urine. The OHSU Biochemical Genetics Laboratory is dedicated to providing specialized laboratory testing and comprehensive diagnostic evaluation of rare and unusual inherited metabolic diseases. Our expertise includes interpretation of results which requires detailed knowledge of the field by individuals specializing in clinical biochemical genetics.

Proper citation: OHSU Biochemical Genetics Laboratory (RRID:SCR_009964) Copy   

•   Source: SciCrunch Registry

http://ohsu.eagle-i.net/i/0000013c-e05d-718e-6d01-360380000000

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on December 6,2022. Core facility provides the following services: Data Management Consultation, Research Databases: REDCap & Customized Databases, Functional Genomics Consultation: Microarray Proteomics. The Biomedical Informatics Program (BMIP) provides investigators with informatics tools and methodologies to support translational researchers. Using a hybrid of collaborative and service approaches, BMIP is continually developing and deploying an array of informatics tools for bench research (bioinformatics), bedside research (clinical research informatics), and translation to practice (medical informatics). BMIP also provides a platform for collaborative and multidisciplinary informatics education and research. The Biomedical Informatics Program includes two major areas of emphasis: Translational Bioinformatics - Novel methodology development, Statistical Genetics, Functional Genomics, Clinical Research Informatics, Research Data Warehouse - Using Epic and other clinical data for research, Clinical research data management software, Epic as an interventional tool for research

Proper citation: Oregon Clinical and Translational Research Institute Biomedical Informatics Program (RRID:SCR_009965) Copy   

•   Source: SciCrunch Registry

https://www.ohsu.edu/pharmacokinetics-core

Core for analysis of drugs and their metabolites and bio-molecules such as simple peptides, oligonucleotides, carbohydrates, lipids, fatty acids and steroids. Provides open access to laboratory where users prepare and analyze their own samples by HPLC, GC/MS or LC/MS on equipment maintained by core personnel. Provides analysis of samples including development of analytical methods, sample preparation, and data analysis for clinical trials as well as basic science investigations.

Proper citation: OHSU Bioanalytical Shared Resource Pharmacokinetics Core Facility (RRID:SCR_009963) Copy   

•   Source: SciCrunch Registry

https://www.ohsu.edu/advanced-imaging-research-center/about-advanced-imaging-research-center

Provides magnetic resonance instruments including Siemens 3 Tesla Prisma, Siemens Magnetom 7 Tesla, and Bruker 11.75 Tesla to support research investigating normal physiology, brain development and aging, and disease pathophysiology with high performance non invasive imaging capabilities.

Proper citation: OHSU Advanced Imaging Research Center Core Facility (RRID:SCR_009960) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012e-5946-2efe-55da-381e80000000

The Biostatistics Center provides support to MGH investigators, as well as serving as a Coordinating Center for several NIH-supported projects. The Center''s staff includes biostatisticians, physicians, research nurses, data managers, project managers, research assistants, and computing staff.

Proper citation: MGH Biostatistics Center (RRID:SCR_009913) Copy   

•   Source: SciCrunch Registry