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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
deepSNV
 
Resource Report
Resource Website
10+ mentions
deepSNV (RRID:SCR_006214) deepSNV software resource Software package that provides quantitative variant callers for detecting subclonal mutations in ultra-deep (>=100x coverage) sequencing experiments. The algorithm is used for a comparative setup with a control experiment of the same loci and uses a beta-binomial model and a likelihood ratio test to discriminate sequencing errors and subclonal SNVs (single nucleotide variants). data import, genetic variability, genetics, snp, sequencing, single nucleotide variant, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
PMID:24443148 GNU General Public License, v3 OMICS_02239, biotools:deepsnv https://bio.tools/deepsnv SCR_006214 deepSNV - Detection of subclonal SNVs in deep sequencing experiments 2026-08-01 12:03:05 34
SRAdb
 
Resource Report
Resource Website
10+ mentions
SRAdb (RRID:SCR_006524) SRAdb software resource Software package to make access to the compilation of metadata from NCBI SRA and tools associated with submission, study, sample, experiment and run much more feasible. This is accomplished by parsing all the NCBI SRA metadata into a SQLite database that can be stored and queried locally. Fulltext search in the package make querying metadata very flexible and powerful. fastq and sra files can be downloaded for doing alignment locally. Beside ftp protocol, the SRAdb has funcitons supporting fastp protocol (ascp from Aspera Connect) for faster downloading large data files over long distance. The SQLite database is updated regularly as new data is added to SRA and can be downloaded at will for the most up-to-date metadata. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: NCBI Sequence Read Archive (SRA)
has parent organization: Bioconductor
PMID:23323543 Artistic License, v2 biotools:sradb, OMICS_01032 https://bio.tools/sradb SCR_006524 SRAdb - A compilation of metadata from NCBI SRA and tools 2026-08-01 12:03:09 18
MethylSeekR
 
Resource Report
Resource Website
50+ mentions
MethylSeekR (RRID:SCR_006513) MethylSeekR software resource A software package for the discovery of regulatory regions from Bis-seq data. is listed by: OMICtools
has parent organization: Bioconductor
GNU General Public License, v2 or greater OMICS_00607 SCR_006513 MethylSeekR - Segmentation of Bis-seq data 2026-08-01 12:03:13 54
casper
 
Resource Report
Resource Website
100+ mentions
casper (RRID:SCR_006613) casper software resource Software to infer alternative splicing from paired-end RNA-seq data. The model is based on counting paths across exons, rather than pairwise exon connections, and estimates the fragment size and start distributions non-parametrically, which improves estimation precision. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
GNU General Public License, v2 or greater biotools:casper, OMICS_01270 https://bio.tools/casper SCR_006613 casper - Characterization of Alternative Splicing based on Paired-End Reads, Characterization of Alternative Splicing based on Paired-End Reads 2026-08-01 12:03:13 149
ChIPXpress
 
Resource Report
Resource Website
1+ mentions
ChIPXpress (RRID:SCR_006653) ChIPXpress software resource A R package designed to improve ChIP-seq and ChIP-chip target gene ranking using publicly available gene expression data. It takes as input predicted transcription factor (TF) bound genes from ChIPx data and uses a corresponding database of gene expression profiles downloaded from NCBI GEO to rank the TF bound targets in order of which gene is most likely to be functional TF target. gene expression, chip-seq, chip-chip, transcription factor, target gene, gene, gene expression profile is listed by: OMICtools
is related to: Gene Expression Omnibus
has parent organization: Bioconductor
GNU General Public License, v2 or greater OMICS_00516 SCR_006653 ChIPXpress: enhanced transcription factor target gene identification from ChIP-seq and ChIP-chip data using publicly available gene expression profiles 2026-08-01 12:03:17 2
ddCt
 
Resource Report
Resource Website
100+ mentions
ddCt (RRID:SCR_003396) ddCt software resource Software package providing an approximation method to determine relative gene expression with quantitative real-time PCR (qRT-PCR) experiments. It requires no standard curve for each primer-target pair, therefore reducing the working load and yet returning accurate enough results as long as the assumptions of the amplification efficiency hold. The package implements a pipeline to collect, analyze and visualize qRT-PCR results, for example those from TaqMan SDM software, mainly using the ddCt method. The pipeline can be either invoked by a script in command-line or through the API consisting of S4-Classes, methods and functions. differential expression, gene expression, microtitre plate assay, q-pcr is listed by: OMICtools
has parent organization: Bioconductor
Free, Available for download, Freely available OMICS_02312 SCR_003396 Delta-Delta-Ct 2026-08-01 12:02:10 321
ggbio
 
Resource Report
Resource Website
10+ mentions
ggbio (RRID:SCR_003313) software resource An R package for extending the grammar of graphics for genomic data. The graphics are designed to answer common scientific questions, in particular those often asked of high throughput genomics data. All core Bioconductor data structures are supported, where appropriate. The package supports detailed views of particular genomic regions, as well as genome-wide overviews. Supported overviews include ideograms and grand linear views. High-level plots include sequence fragment length, edge-linked interval to data view, mismatch pileup, and several splicing summaries. standalone software, unix/linux, mac os x, windows, r, infrastructure, visualization, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
PMID:22937822 Free, Available for download, Freely available biotools:ggbio, OMICS_04660 http://www.tengfei.name/ggbio/, https://bio.tools/ggbio SCR_003313 ggbio - Visualization tools for genomic data 2026-08-01 12:02:29 14
OmicCircos
 
Resource Report
Resource Website
50+ mentions
OmicCircos (RRID:SCR_003292) software resource An R software application and package used to generate high-quality circular plots for visualizing genomic variations, including mutation patterns, copy number variations (CNVs), expression patterns, and methylation patterns. standalone software, unix/linux, mac os x, windows, r, annotation, statistical method, visualization is listed by: OMICtools
has parent organization: Bioconductor
PMID:24526832 Free, Available for download, Freely available OMICS_04659 http://www.bioconductor.org/packages/release/bioc/html/OmicCircos.html SCR_003292 OmicCircos: High-quality circular visualization of omic data 2026-08-01 12:02:07 79
MBASED
 
Resource Report
Resource Website
10+ mentions
MBASED (RRID:SCR_002584) software resource Software package containing functions for allele-specific gene expression (ASE) analysis using meta-analysis based allele-specific expression detection. software package, unix/linux, mac os x, windows, r, gene expression, sequencing, transcription is listed by: OMICtools
has parent organization: Bioconductor
PMID:25315065 Free, Available for download, Freely available OMICS_05502 http://www.bioconductor.org/packages/release/bioc/html/MBASED.html SCR_002584 Meta-analysis Based Allele-Specific Expression Detection, MBASED - Package containing functions for ASE analysis using Meta-analysis Based Allele-Specific Expression Detection 2026-08-01 12:01:51 17
sapFinder
 
Resource Report
Resource Website
sapFinder (RRID:SCR_002685) software resource An R software package, for detection of the variant peptides based on tandem mass spectrometry (MS/MS)-based proteomics data. It automates (1) variation-associated database construction, (2) database searching, (3) post-processing, (4) HTML-based report generation in shotgun proteomics. standalone software, r, mass spectrometry, proteomics, rna-seq, report writing, snp, visualization, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
PMID:25053745 Free, Available for download, Freely available biotools:sapfinder, OMICS_05285 https://bio.tools/sapfinder SCR_002685 sapFinder - A package for variant peptides detection and visualization in shotgun proteomics. 2026-08-01 12:02:12 0
Pathview
 
Resource Report
Resource Website
500+ mentions
Pathview (RRID:SCR_002732) software resource A tool set for pathway-based data integration and visualization. It maps and renders a wide variety of biological data on relevant pathway graphs. All users need is to supply their data and specify the target pathway. Pathview automatically downloads the pathway graph data, parses the data file, maps user data to the pathway, and render pathway graph with the mapped data. In addition, Pathview also seamlessly integrates with pathway and gene set (enrichment) analysis tools for large-scale and fully automated analysis. software package, r, differential expression, gene expression, gene set enrichment, genetics, graph, network, metabolomics, microarray, pathway, proteomics, rna-seq, sequencing, systems biology, visualization, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
PMID:23740750 Free, Freely available, Available for download biotools:pathview, OMICS_05212 http://pathview.r-forge.r-project.org/, https://bio.tools/pathview SCR_002732 path view 2026-08-01 12:02:13 520
Basic4Cseq
 
Resource Report
Resource Website
1+ mentions
Basic4Cseq (RRID:SCR_002836) software resource An R/Bioconductor package for basic filtering, analysis and subsequent near-cis visualization of 4C-seq data. Virtual fragment libraries can be created for any BSGenome package, and filter functions for both reads and fragments and basic quality controls are included. Fragment data in the vicinity of the experiment's viewpoint can be visualized as a coverage plot based on a running median approach and a multi-scale contact profile. software package, unix/linux, mac os x, windows, r, quality control, visualization is listed by: OMICtools
has parent organization: Bioconductor
PMID:25078398 Free, Freely available, Available for download OMICS_05202 SCR_002836 Basic4Cseq: an R/Bioconductor package for analyzing 4C-seq data 2026-08-01 12:02:14 6
mzR
 
Resource Report
Resource Website
mzR (RRID:SCR_002856) software resource Software that provides a unified API to the common file formats and parsers available for mass spectrometry data. It comes with a wrapper for the ISB random access parser for mass spectrometry mzXML, mzData and mzML files. standalone software, mac os x, unix/linux, windows, r, data import, infrastructure, mass spectrometry, metabolomics, proteomics is listed by: OMICtools
has parent organization: Bioconductor
Free, Freely available, Available for download OMICS_02654 SCR_002856 mzR - parser for netCDF mzXML mzData and mzML and mzIdentML files 2026-08-01 12:02:14 0
BiGGR
 
Resource Report
Resource Website
BiGGR (RRID:SCR_002854) software resource Software package that provides an interface to simulate metabolic reconstruction from the BiGG database and other metabolic reconstruction databases. The package facilitates flux balance analysis (FBA) and the sampling of feasible flux distributions. Metabolic networks and estimated fluxes can be visualized with hypergraphs. standalone software, mac os x, unix/linux, windows, r, metabolomics, network, visualization, metabolic reconstruction, model uses: BiGG Database
is listed by: OMICtools
has parent organization: Bioconductor
PMID:25806817 Free, Freely available, Available for download OMICS_02655 SCR_002854 BiGGR - Constraint based modeling in R using metabolic reconstruction databases 2026-08-01 12:02:19 0
PAPi
 
Resource Report
Resource Website
50+ mentions
PAPi (RRID:SCR_002857) software resource An R package for predicting the activity of metabolic pathways based solely on a metabolomics data set containing a list of metabolites identified and their respective abundances in different biological samples. PAPi generates hypothesis that improves the final biological interpretation. standalone software, mac os x, unix/linux, windows, r, mass spectrometry, metabolomics is listed by: OMICtools
has parent organization: Bioconductor
PMID:20929912 Free, Freely available, Available for download OMICS_02653 SCR_002857 PAPi - Predict metabolic pathway activity based on metabolomics data, Pathway Activity Profiling 2026-08-01 12:02:19 53
tweeDEseq
 
Resource Report
Resource Website
1+ mentions
tweeDEseq (RRID:SCR_003038) software resource Software for differential expression analysis of RNA-seq using the Poisson-Tweedie family of distributions. standalone software, unix/linux, mac os x, windows, c, r, rna-seq, differential expression, sequencing, statistical method, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
PMID:23965047 Free, Available for download, Freely available OMICS_02406, biotools:tweedeseq https://bio.tools/tweedeseq SCR_003038 tweeDEseq: RNA-seq data analysis using the Poisson-Tweedie family of distributions 2026-08-01 12:02:00 4
BRAIN
 
Resource Report
Resource Website
10+ mentions
BRAIN (RRID:SCR_003018) software resource Software package for calculating aggregated isotopic distribution and exact center-masses for chemical substances (in this version composed of C, H, N, O and S). standalone software, mac os x, unix/linux, windows, r, mass spectrometry, proteomics, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
PMID:23350948 GNU General Public License, v2 biotools:brain, OMICS_02410 https://bio.tools/brain SCR_003018 Baffling Recursive Algorithm for Isotopic distributioN calculations, Baffling Recursive Algorithm for Isotope distributioN 2026-08-01 12:02:15 44
SurvComp
 
Resource Report
Resource Website
50+ mentions
SurvComp (RRID:SCR_003054) survcomp software resource R package providing functions to assess and to compare the performance of risk prediction (survival) models. differential expression, gene expression, visualization, mac os x, unix/linux, windows, r is listed by: OMICtools
has parent organization: Bioconductor
PMID:21903630 Free, Available for download, Freely available OMICS_02373 SCR_003054 survcomp - Performance Assessment and Comparison for Survival Analysis 2026-08-01 12:02:16 58
massiR
 
Resource Report
Resource Website
massiR (RRID:SCR_001157) software resource Software that predicts the sex of samples in gene expression microarray datasets. standalone software, mac os x, unix/linux, windows, r, classification, clustering, gene expression, microarray, quality control, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
PMID:24659105 Free, Available for download, Freely available biotools:massir, OMICS_03638 https://bio.tools/massir SCR_001157 massiR: MicroArray Sample Sex Identifier, MicroArray Sample Sex Identifier 2026-08-01 12:01:33 0
yaqcaffy
 
Resource Report
Resource Website
1+ mentions
yaqcaffy (RRID:SCR_001295) yaqcaffy software resource Software package for quality control of Affymetrix GeneChip expression data and reproducibility analysis of human whole genome chips with the MAQC reference datasets. microarray, one channel, quality control, report writing, affymetrix, gene expression, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
Free, Available for download, Freely available BioTools:yaqcaffy, biotools:yaqcaffy, OMICS_02040 http://www.bioconductor.org/packages/release/bioc/html/yaqcaffy.html SCR_001295 yaqcaffy - Affymetrix expression data quality control and reproducibility analysis 2026-08-01 12:01:27 2

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