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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
SCALCE
 
Resource Report
Resource Website
SCALCE (RRID:SCR_009658) SCALCE software resource A FASTQ compression tool that uses locally consistent parsing to obtain better compression rate. is listed by: OMICtools
has parent organization: SourceForge
OMICS_00969 SCR_009658 Boosting Sequence Compression Algorithms using Locally Consistent Encoding 2026-08-01 12:03:45 0
Bycom
 
Resource Report
Resource Website
Bycom (RRID:SCR_000659) software resource A software which can perform methylcytosine calling from BS-seq (WGBS and RRBS), and permits either unmapped reads (FASTQ) or mapped reads (SAM/BAM) to be used as the input data. Certain SNPs (C>A/G) can also be selected in the output. methylcytosine, bs-seq, fastq, sam, bam, snps, snp, wgbs, rrbs, sorftw is listed by: OMICtools
has parent organization: SourceForge
PMID:25255082 Free, Available for download, Freely available OMICS_00594 SCR_000659 2026-08-01 12:08:11 0
OrChem
 
Resource Report
Resource Website
1+ mentions
OrChem (RRID:SCR_008865) OrChem software resource, source code OrChem is an extension for the Oracle 11G database that adds registration and indexing of chemical structures to support fast substructure and similarity searching. The cheminformatics functionality is provided by the Chemistry Development Kit. OrChem provides similarity searching with response times in the order of seconds for databases with millions of compounds, depending on a given similarity cut-off. For substructure searching, it can make use of multiple processor cores on today''s powerful database servers to provide fast response times in equally large data sets. OrChem is an Oracle chemistry plug-in using the Chemistry Development Kit (CDK). The CDK is an open source Java library for Chemoinformatics and Bioinformatics. OrChem is maintained by the chemoinformatics and metabolism team of the European Bioinformatics Institute. Oracle Data cartridges extend the capabilities of the Oracle server. For chemistry various commercial cartridges exist that facilitate searching and analyzing chemical data. OrChem also provides functionality like this, but is not a cartridge. It doesn''t need Oracle''s extensibility architecture because its Java components run as Java stored procedures inside the Oracle standard JVM (Aurora). OrChem is suitable for Oracle 11G and onwards. Starting with Oracle 11g release 1 (11.1) there is a just-in-time(JIT) compiler for Oracle JVM environment. A JIT compiler for Oracle JVM enables much faster execution because it manages the invalidation, recompilation, and storage of code without an external mechanism. This new Oracle feature makes Java classes perform better than before. oracle, chemistry, cdk, similarity search, chemical structure, cheminformatics, bioinformatics, plugin is listed by: 3DVC
has parent organization: SourceForge
has parent organization: European Bioinformatics Institute
PMID:20298521 GNU Lesser General Public License nlx_149252 SCR_008865 2026-08-03 09:34:14 1
BamView
 
Resource Report
Resource Website
10+ mentions
BamView (RRID:SCR_004207) BamView software resource, source code A free interactive display of read alignments in BAM data files that can be launched with Java Web Start or downloaded. This interactive Java application for visualizing the large amounts of data stored for sequence reads which are aligned against a reference genome sequence can be used in a number of contexts including SNP calling and structural annotation. It has been integrated into Artemis so that the reads can be viewed in the context of the nucleotide sequence and genomic features. The source code is available as part of the Artemis code which can be downloaded from GitHub. bam, next-generation sequencing, java, snp calling, structural annotation, macosx, unix, windows, visualize, analyze, sequence read, reference sequence, single nucleotide polymorphism, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: SourceForge
has parent organization: Wellcome Trust Sanger Institute; Hinxton; United Kingdom
PMID:22253280
PMID:20071372
GNU General Public License biotools:bamview, OMICS_00878, nlx_22933 https://bio.tools/bamview SCR_004207 2026-08-03 09:32:23 21
OWL API
 
Resource Report
Resource Website
10+ mentions
OWL API (RRID:SCR_005734) OWL API software resource, source code The OWL API is a Java API and reference implementation for creating, manipulating and serializing OWL Ontologies. The latest version of the API is focused towards OWL 2. The OWLAPI underpins ontology browsing and editing tools and platforms such as SWOOP and Protege4. Note that this API, or any other OWL-based API, can be used without an integrated OWL parser if you download a pre-converted OWL file generated from OBO. See OBO Ontologies List for all OBO ontologies converted to OWL (we do not list the full complement of OWL-based APIs here, only those of direct relevance to GO). The OWL API includes the following components: * An API for OWL 2 and an efficient in-memory reference implementation * RDF/XML parser and writer * OWL/XML parser and writer * OWL Functional Syntax parser and writer * Turtle parser and writer * KRSS parser * OBO Flat file format parser * Reasoner interfaces for working with reasoners such as FaCT++, HermiT, Pellet and Racer Platform: Windows compatible, Mac OS X compatible, Linux compatible, Unix compatible ontology, owl, api, java, software library, parser, writer is listed by: Gene Ontology Tools
is related to: Gene Ontology
has parent organization: University of Manchester; Manchester; United Kingdom
has parent organization: SourceForge
Open unspecified license - Free for academic use; available under either the LGPL or Apache Licenses nlx_149195 SCR_005734 The OWL API, OWLAPI 2026-08-03 09:32:55 15
ALCHEMY
 
Resource Report
Resource Website
1+ mentions
ALCHEMY (RRID:SCR_005761) ALCHEMY software resource, source code ALCHEMY is a genotype calling algorithm for Affymetrix and Illumina products which is not based on clustering methods. Features include explicit handling of reduced heterozygosity due to inbreeding and accurate results with small sample sizes. ALCHEMY is a method for automated calling of diploid genotypes from raw intensity data produced by various high-throughput multiplexed SNP genotyping methods. It has been developed for and tested on Affymetrix GeneChip Arrays, Illumina GoldenGate, and Illumina Infinium based assays. Primary motivations for ALCHEMY''s development was the lack of available genotype calling methods which can perform well in the absence of heterozygous samples (due to panels of inbred lines being genotyped) or provide accurate calls with small sample batches. ALCHEMY differs from other genotype calling methods in that genotype inference is based on a parametric Bayesian model of the raw intensity data rather than a generalized clustering approach and the model incorporates population genetic principles such as Hardy-Weinberg equilibrium adjusted for inbreeding levels. ALCHEMY can simultaneously estimate individual sample inbreeding coefficients from the data and use them to improve statistical inference of diploid genotypes at individual SNPs. The main documentation for ALCHEMY is maintained on the sourceforge-hosted MediaWiki system. Features * Population genetic model based SNP genotype calling * Simultaneous estimation of per-sample inbreeding coefficients, allele frequencies, and genotypes * Bayesian model provides posterior probabilities of genotype correctness as quality measures * Growing number of scripts and supporting programs for validation of genotypes against control data and output reformating needs * Multithreaded program for parallel execution on multi-CPU/core systems * Non-clustering based methods can handle small sample sets for empirical optimization of sample preparation techniques and accurate calling of SNPs missing genotype classes ALCHEMY is written in C and developed on the GNU/Linux platform. It should compile on any current GNU/Linux distribution with the development packages for the GNU Scientific Library (gsl) and other development packages for standard system libraries. It may also compile and run on Mac OS X if gsl is installed. diploid, genotype, snp, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: SourceForge
has parent organization: Cornell University; New York; USA
NSF 0606461 PMID:20926420 GNU General Public License biotools:alchemy, nlx_149227 https://bio.tools/alchemy SCR_005761 ALCHEMY - An automated population genetic model driven SNP genotype calling method 2026-08-03 09:32:55 5
Neurofitter
 
Resource Report
Resource Website
1+ mentions
Neurofitter (RRID:SCR_005843) Neurofitter software resource, source code Neurofitter is software for parameter tuning of electrophysiological neuron models. It automatically searches for sets of parameters of neuron models that best fit available experimental data, and therefore acts as an interface between neuron simulators, like Neuron or Genesis, and optimization algorithms, like Particle Swarm Optimization, Evolutionary Strategies, etc. neuron, parameter, tuning, electrophysiology, model, neuron simulator, neuron model has parent organization: SourceForge
has parent organization: University of Antwerp; Antwerp; Belgium
has parent organization: Brandeis University; Massachusetts; USA
has parent organization: Okinawa Institute of Science and Technology
Okinawa Institute of Science and Technology PMID:18974796 GNU General Public License, v2 nlx_149366 SCR_005843 2026-08-03 09:32:48 1
BAIT
 
Resource Report
Resource Website
1+ mentions
BAIT (RRID:SCR_000511) BAIT data processing software, data analysis software, software resource, software application, data visualization software Software to create strand inheritance plots in data derived from the Strand-Seq sequencing protocol. The software is designed to be flexible with a range of species, and basic template folders can called to read in species-specific data. create strand inheritance plots, strand-seq, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: SourceForge
PMID:24028793 Free, Available for download, Freely available biotools:bait, OMICS_01531 https://bio.tools/bait SCR_000511 BAIT - Software to help analyse Strand-Seq data 2026-08-04 09:40:09 1
POPBAM
 
Resource Report
Resource Website
POPBAM (RRID:SCR_000464) POPBAM data processing software, software application, software resource, data analysis software A tool to perform evolutionary or population-based analyses of next-generation sequencing data. POPBAM takes a BAM file as its input and can compute many widely used evolutionary genetics measures in sliding windows across a genome. next-generation sequencing, evolution, population, bam, genome, evolutionary genetics, c++, short read, sequence alignment, sliding window, command-line, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: SourceForge
has parent organization: University of Rochester; New York; USA
PMID:24027417 Free, Available for download, Freely available biotools:popbam, OMICS_01559 https://bio.tools/popbam http://popbam.sourceforge.net/ SCR_000464 2026-08-04 09:40:08 0
AutoAssemblyD
 
Resource Report
Resource Website
AutoAssemblyD (RRID:SCR_001087) data processing software, data analysis software, software resource, sequence analysis software, software application Software which performs local and remote genome assembly by several assemblers based on an XML Template which can replace the large command lines required by most assemblers. genome, genome assembly, xml, sequence analysis software, local genome assembly, remote genome assembly, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: SourceForge
PMID:24143057 Free, Available for download, Freely available biotools:autoassemblyd, OMICS_00874 https://bio.tools/autoassemblyd SCR_001087 2026-08-04 09:40:18 0
Mutascope
 
Resource Report
Resource Website
1+ mentions
Mutascope (RRID:SCR_001265) Mutascope data processing software, software application, software resource, data analysis software Software suite to analyze data from high throughput sequencing of PCR amplicons, with an emphasis on normal-tumor comparison for the accurate and sensitive identification of low prevalence mutations. high throughput sequencing, pcr amplicon, pcr, mutation, amplicon, sequencing, somatic variant is listed by: OMICtools
has parent organization: SourceForge
Tumor, Normal PMID:23712659 Free, Public OMICS_02074 SCR_001265 Mutascope - Analysis software designed for PCR-amplicon sequencing data 2026-08-04 09:40:21 4
Drosophila anatomy and development ontologies
 
Resource Report
Resource Website
Drosophila anatomy and development ontologies (RRID:SCR_001607) FBbt ontology, data or information resource, controlled vocabulary A structured controlled vocabulary of the anatomy of Drosophila melanogaster. These ontologies are query-able reference sources for information on Drosophila anatomy and developmental stages. They also provide controlled vocabularies for use in annotation and classification of data related to Drosophila anatomy, such as gene expression, phenotype and images. They were originally developed by FlyBase, who continue to maintain them and have used them for over 200,000 annotations of phenotypes and expression. Extensive use of synonyms means that, given a suitably sophisticated autocomplete, users can find relevant content by searching with almost any anatomical term they find in the literature. These ontologies are developed in the web ontology language OWL2. Their extensive formalization in OWL can be used to drive sophisticated query systems. anatomy, development, developmental stage, gene expression, phenotype, owl is related to: OBO
is related to: Flannotator
is related to: REDfly Regulatory Element Database for Drosophilia
is related to: Bgee: dataBase for Gene Expression Evolution
has parent organization: FlyBase
has parent organization: SourceForge
NHGRI P41 HG000739 Free, Freely available nlx_153871 SCR_001607 Drosophila anatomy & dev ontologies 2026-08-04 09:40:25 0
Mugsy
 
Resource Report
Resource Website
50+ mentions
Mugsy (RRID:SCR_001414) data processing software, data analysis software, software resource, sequence analysis software, software application Software resource for multiple whole genome alignment. It uses Nucmer, a custom graph-based segmentation procedure, for pairwise alignment, and the Seqan:TCoffee's multiple alignment strategy. software, genome, genome alignment, segmentation, pairwise alignment, sequence analysis software is listed by: OMICtools
is listed by: Debian
has parent organization: SourceForge
PMID:21148543
DOI:10.1093/bioinformatics/btq665
Free, Available for download, Freely available OMICS_03606 https://sources.debian.org/src/mugsy/ SCR_001414 2026-08-04 09:40:22 71
SCRalyze
 
Resource Report
Resource Website
10+ mentions
SCRalyze (RRID:SCR_002542) SCRalyze data processing software, software application, software resource, data analysis software A powerful software for model-based analysis of peripheral psychophysiology (e.g. skin conductance, heart rate, pupil size etc.). General linear modelling and dynamic causal modelling of these signals provide for inference on neural states/processes. SCRalyze includes flexible data import and display, statistical inference and results display and export. Easy programming of add-ons for new data formats, signal channels, and models. eeg, meg, electrocorticography, matlab, modeling, os independent, quantification, time domain analysis is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
has parent organization: SourceForge
Free, Available for download, Freely available nlx_155950 http://www.nitrc.org/projects/scralyze SCR_002542 SCRalyze - A matlab environment for model-based psychophysiology 2026-08-04 09:40:40 17
NIDB - Neuroinformatics Database
 
Resource Report
Resource Website
1+ mentions
NIDB - Neuroinformatics Database (RRID:SCR_002488) NIDB data management software, software resource, software application, database, data or information resource Neuroimaging database designed to allow simple importing, searching, and sharing of imaging data. NIDB also provides automated pipelining with importing of results back into NIDB which can be searched along with imaging meta data. connectome file format, clinical neuroinformatics, computational neuroscience, computed tomography, imaging genomics, interfile, javascript, neuroimaging is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
has parent organization: SourceForge
PMID:25888923 Free, Available for download, Freely available nlx_155882 http://www.nitrc.org/projects/nidb http://nidb.sourceforge.net/ SCR_002488 Neuroinformatics Database 2026-08-04 09:40:40 2
ANDES
 
Resource Report
Resource Website
10+ mentions
ANDES (RRID:SCR_002791) data processing software, data analysis software, software resource, software application, software toolkit Software library and a suite of applications, written in Perl and R, for deep sequencing statistical analyses. deep sequencing, biomarker detection, statistical analysis, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: SourceForge
PMID:20633290 Free, Freely available, Available for download biotools:andes, OMICS_01119 https://bio.tools/andes SCR_002791 Statistical tools for the Analyses of Deep Sequencing (ANDES), Statistical tools for the Analyses of Deep Sequencing, Statistical tools for the ANalyses of Deep Sequencing 2026-08-04 09:40:44 25
Rainbow
 
Resource Report
Resource Website
10+ mentions
Rainbow (RRID:SCR_002724) data processing software, data analysis software, software resource, sequence analysis software, software application Software developed to provide an ultra-fast and memory-efficient solution to clustering and assembling short reads produced by RAD-seq. software, tool, clustering, assembling, short, read, restriction, site, DNA, sequence, analysis, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
PMID:22942077
DOI:10.1093/bioinformatics/bts482
Free, Freely available, Available for download SCR_015992, OMICS_03722, biotools:rainbow https://bio.tools/rainbow, https://sources.debian.org/src/bio-rainbow/ SCR_002724 RAD-seq: Restriction-site Associated DNA sequencing, Bio-rainbow, RAD-seq 2026-08-04 09:40:43 41
GMATo
 
Resource Report
Resource Website
1+ mentions
GMATo (RRID:SCR_000165) data processing software, data analysis software, software resource, sequence analysis software, software application A software tool used for simple sequence repeats (SSR) or microsatellite characterization. It also facilitates SSR marker design on a genomic scale, microsatellite mining at any length, and comprehensive statistical analysis for DNA sequences in any genome at any size. Analysis parameters are customizable. simple sequence repeat, ssr, microsatellite, genomic, marker design, sequence analysis software is listed by: OMICtools
has parent organization: SourceForge
PMID:23861572 Free, Available for download, Freely available OMICS_00106 SCR_000165 Genome-wide Microsatellite Analyzing Tool, Genome Microsatellite Analyzing Tool, Genome-wide Microsatellite Analyzing Tool (GMATo) 2026-08-04 09:40:04 1
BlackOPs
 
Resource Report
Resource Website
BlackOPs (RRID:SCR_000032) data processing software, data analysis software, software resource, sequence analysis software, software application Open source software tool that simulates experimental RNA-seq and DNA whole exome sequences derived from reference genome, aligns these sequences by custom parameters, detects variants and outputs blacklist of positions and alleles caused by mismapping. Used to characterize mappability of RNA-Seq reads and create blacklist of genomic positions of mismapped reads. This blacklist is used to filter potential false positives from variant or RNA editing calls. rna seq, false positive, genome editing, rna editing, mismapped reads has parent organization: SourceForge PMID:23935067 Free, Available for download, Freely available OMICS_01229 SCR_000032 BlackOPs: RNA-Seq Variant Blacklist Tool 2026-08-04 09:40:02 0
skewer
 
Resource Report
Resource Website
10+ mentions
skewer (RRID:SCR_001151) skewer data processing software, software application, software resource Software program for adapter trimming that is specially designed for processing Illumina paired-end sequences. illumina, unix/linux, c++, adapter trimming, paired-end, sequence, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
PMID:24925680 Free, Available for download, Freely available OMICS_02106, biotools:skewer https://bio.tools/skewer, https://sources.debian.org/src/skewer/, https://github.com/relipmoc/skewer SCR_001151 skewer - A fast and sensitive adapter trimmer for illumina paired-end sequences 2026-08-04 09:40:19 11

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