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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
HPC-CLUST
 
Resource Report
Resource Website
1+ mentions
HPC-CLUST (RRID:SCR_005052) HPC-CLUST software resource A set of tools designed to cluster large numbers (>1 million) of pre-aligned nucleotide sequences. It performs the clustering of sequences using the Hierarchical Clustering Algorithm (HCA). There are currently three different cluster metrics implemented: single-linkage, complete-linkage, and average-linkage. In addition, there are currently four sequence distance functions implemented, these are: identity (gap-gap counting as match), nogap (gap-gap being ignored), nogap-single (like nogap, but consecutive gap-nogap''s count as a single mismatch), tamura (distance is calculated with the knowledge that transitions are more likely than transversions). One advantage that HCA has over other algorithms is that instead of producing only the clustering at a given threshold, it produces the set of merges occuring at each threshold. With this approach, the clusters can afterwards very quickly be reported for every arbitrary threshold with little extra computation. This approach also allows the plotting of the variation of number of clusters with clustering threshold without requiring the clustering to be run for each threshold independently. Another feature of the way HPC-CLUST is implemented is that the single-, complete-, and average-linkage clusterings can be computed in a single run with little overhead. c++, mpi is listed by: OMICtools
has parent organization: University of Zurich; Zurich; Switzerland
PMID:24215029 OMICS_01446 SCR_005052 2026-08-01 12:02:48 5
M-pick
 
Resource Report
Resource Website
M-pick (RRID:SCR_004995) M-pick software resource A modularity-based clustering software for Operational Taxonomic Unit (OTU) picking of 16S rRNA sequences. The algorithm does not require a predetermined cut-off level, and our simulation studies suggest that it is superior to existing methods that require specified distance or variance levels to define OTUs. 16s rrna sequence, 16s rrna, rrna, sequence, binning is listed by: OMICtools
has parent organization: University of Florida; Florida; USA
OMICS_01447 SCR_004995 M-pick: a modularity-based clustering method for OTU picking 2026-08-01 12:02:51 0
University of Manchester; Manchester; United Kingdom
 
Resource Report
Resource Website
1+ mentions
University of Manchester; Manchester; United Kingdom (RRID:SCR_004996) university Public research university in Manchester, England, formed in 2004 by merger of University of Manchester Institute of Science and Technology and Victoria University of Manchester. Second largest university in United Kingdom by enrollment. is affiliated with: OpenMinTeD
is related to: NEWMEDS
is related to: ORBITO
is related to: Open PHACTS
is related to: EMIF
is parent organization of: Smart Dictionary Lookup
is parent organization of: mlgt
is parent organization of: Utopia Docs
is parent organization of: Kidney and Urinary Pathway Knowledge Base
is parent organization of: PUMA
is parent organization of: DOSY Toolbox
is parent organization of: RightField
is parent organization of: SEEK
is parent organization of: miRBase
is parent organization of: PRINTS
is parent organization of: CHEM21
is parent organization of: Taverna
is parent organization of: SysMO-DB
is parent organization of: MethodBox
is parent organization of: OWL API
is parent organization of: X:MAP
is parent organization of: Mimas
is parent organization of: National Centre for Text Mining
is parent organization of: Chemistry Using Text Annotations
is parent organization of: TerMine
is parent organization of: Acromine Disambiguator
is parent organization of: Census Dissemination Unit
is parent organization of: Open Regulatory Annotation Database
is parent organization of: ADAPT: A Database of Affymetrix Probesets and Transcripts
is parent organization of: brat rapid annotation tool
is parent organization of: UK DNA Banking Network
is parent organization of: AcroMine
is parent organization of: BioIE: Extracting Informative Sentences From the Biomedical Literature
is parent organization of: Biocatalogue - The Life Science Web Services Registry
is parent organization of: myExperiment
is parent organization of: Software Ontology
is parent organization of: bioNerDS
is parent organization of: MorphoJ
is parent organization of: University of Manchester Bioinformatics Core Facility
is parent organization of: miRBase
is parent organization of: Simple Assignment of Spots to Surfaces
is parent organization of: AMBER parameter database
is parent organization of: University of Manchester Electron Microscopy Core Facility
is parent organization of: University of Manchester Mass Spectrometry and Separations Core Facility
is parent organization of: University of Manchester Advanced Manufacturing Platform Core Facility
is parent organization of: University of Manchester Surface Characterisation Core Facility
is parent organization of: University of Manchester Biochemical and Biophysical Sciences Technology Platform Core Facility
is parent organization of: University of Manchester Corrosion and Materials for Demanding Environments Core Facility
is parent organization of: University of Manchester Magnetic Resonance and Related Technology Platform Core Facility
is parent organization of: University of Manchester X-ray Diffraction Platform Core Facility
is parent organization of: University of Manchester Services and Equipment Core Facility
is parent organization of: University of Manchester Design, Fabrication and Testing Core Facility
is parent organization of: University of Manchester National X-ray Computed Tomography Core Facility
is parent organization of: University of Manchester Advanced Metal Development Core Facility
is parent organization of: University of Manchester BioAutomation and Biofoundry Core Facility
is parent organization of: University of Manchester Biomolecular NMR Core Facility
has organization facet: MANC-RISK-SCREEN
nlx_74265, Wikidata:Q230899, grid.5379.8, ISNI:121662407, Crossref funder ID:501100000770 https://ror.org/027m9bs27 SCR_004996 University of Manchester 2026-08-01 12:02:44 7
Bio X Cell
 
Resource Report
Resource Website
1000+ mentions
Bio X Cell (RRID:SCR_004997) commercial organization Commercial supplier and developer of in vivo antibodies. Provides antibodies and antibody production services. commercial, antibody, reagent, biomedical, research, new hampshire, SCR_019248, nlx_152318 SCR_004997 2026-08-01 12:02:47 4386
ESPRIT-Tree
 
Resource Report
Resource Website
1+ mentions
ESPRIT-Tree (RRID:SCR_005045) ESPRIT-Tree software resource Software for hierarchical Clustering Analysis of Millions of 16S rRNA Pyrosequences in Quasi-linear Time. clustering, 16s rrna, pyrosequence is listed by: OMICtools
has parent organization: University of Florida; Florida; USA
PMID:21596775 OMICS_01445 SCR_005045 ESPRIT-Tree: Hierarchical Clustering Analysis of Millions of 16S rRNA Pyrosequences in Quasi-linear Time 2026-08-01 12:02:53 9
Huazhong University of Science and Technology; Wuhan; China
 
Resource Report
Resource Website
Huazhong University of Science and Technology; Wuhan; China (RRID:SCR_005047) HUST university Public research university located in Guanshan Subdistrict, Hongshan District, Wuhan, Hubei province, China. is parent organization of: AnimalTFDB
is parent organization of: Midbody, Centrosome and Kinetochore
is parent organization of: EPSD Eukaryotic Phosphorylation Site Database
ISNI:0000 0004 0368 7223, grid.33199.31, Wikidata:Q1711196, nlx_144495, Crossref funder ID:501100003397 https://ror.org/00p991c53 SCR_005047 Huazhong University of Science and Technology, Huazhong University of Science & Technology, Huazhong University of Science & Technology; Hubei; China 2026-08-01 12:02:44 0
MBCluster.Seq
 
Resource Report
Resource Website
1+ mentions
MBCluster.Seq (RRID:SCR_005079) MBCluster.Seq software resource Software to cluster genes based on Poisson or Negative-Binomial model for RNA-Seq or other digital gene expression (DGE) data. bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
PMID:24191069 GNU General Public License, >/=v3 OMICS_01417, biotools:mbcluster.seq https://bio.tools/mbcluster.seq SCR_005079 MBCluster.Seq: Model-Based Clustering for RNA-seq Data 2026-08-01 12:02:48 1
University of Kansas; Kansas; USA
 
Resource Report
Resource Website
University of Kansas; Kansas; USA (RRID:SCR_005075) KU university Public research university with its main campus in Lawrence, Kansas, and several satellite campuses, research and educational centers, medical centers, and classes across the state of Kansas. is parent organization of: HistoWeb: Nervous System
is parent organization of: Images from the Clendening Library
is parent organization of: Dockground: Benchmarks, Docoys, Templates, and other knowledge resources for DOCKING
is parent organization of: DB-PABP: a database of polyanion binding proteins
is parent organization of: Autism Genetic Database
is parent organization of: University of Kansas Labs and Facilities
is parent organization of: University of Kansas Protein Production Group Core Facility
is parent organization of: University of Kansas Nuclear Magnetic Resonance Laboratory Core Facility
is parent organization of: University of Kansas Molecular Graphics and Modeling Laboratory Core Facility
is parent organization of: University of Kansas Medical Center; Kansas; USA
is parent organization of: University of Kansas Lawrence Protein Structure and X-ray Crystallography Laboratory Core Facility
is parent organization of: University of Kansas Microscopy and Analytical Imaging Research Resource Core Facility
is parent organization of: University of Kansas Mass Spectrometry and Analytical Proteomics Core Facility
is parent organization of: I-TASSER
is parent organization of: University of Kansas Nanofabrication Core Facility
ISNI:0000 0001 2106 0692, Wikidata:Q52413, nlx_83015, Crossref funder ID:100007859, grid.266515.3 https://ror.org/001tmjg57 SCR_005075 University of Kansas 2026-08-01 12:02:48 0
AGORA
 
Resource Report
Resource Website
50+ mentions
AGORA (RRID:SCR_005070) AGORA software resource An algorithm to use optical map information directly within the de Bruijn graph framework to help produce an accurate assembly of a genome that is consistent with the optical map information provided. AGORA takes as input two data structures: OpMap ? an ordered list of fragment sizes representing the optical map; and Edges ? a list of de Bruijn graph edges with their corresponding sequences. genome assembly, genome, reconstruction is listed by: OMICtools PMID:22856673 OMICS_00039 SCR_005070 Assembly Guided by Optical Restriction Alignment 2026-08-01 12:02:45 99
GRASS
 
Resource Report
Resource Website
50+ mentions
GRASS (RRID:SCR_005071) GRASS software resource A generic algorithm for scaffolding next-generation sequencing assemblies. next-generation sequencing, scaffolding, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
PMID:22492642 GNU General Public License, v3 biotools:GRASS, OMICS_00043 https://bio.tools/GRASS SCR_005071 GRASS: a generic algorithm for scaffolding next-generation sequencing assemblies, GeneRic ASembly Scaffolder 2026-08-01 12:02:48 89
MapAl
 
Resource Report
Resource Website
1+ mentions
MapAl (RRID:SCR_004938) MapAl software resource A software tool for RNA-Seq expression profiling that builds on the established programs Bowtie and Cufflinks. Allowing an incorporation of ''gene models'' already at the alignment stage almost doubles the number of transcripts that can be measured reliably. rna?seq is listed by: OMICtools
has parent organization: BOKU University; Vienna; Austria
PMID:22485116 GNU General Public License OMICS_01261 SCR_004938 2026-08-01 12:02:43 1
Open University; Milton Keynes; United Kingdom
 
Resource Report
Resource Website
1+ mentions
Open University; Milton Keynes; United Kingdom (RRID:SCR_004931) OU university Public research university and the largest university in the UK for undergraduate education. The majority of the OU's undergraduate students are based in the United Kingdom and principally study off-campus; many of its courses can also be studied anywhere in the world. is affiliated with: OpenMinTeD
is parent organization of: Scholarly Ontologies Project
is parent organization of: Cohere
is parent organization of: Rexplore
Wikidata:Q2413375, nlx_19814, grid.10837.3d, ISNI:96069301, Crossref funder ID:100008509 https://ror.org/05mzfcs16 SCR_004931 Open University, The Open University 2026-08-01 12:02:43 3
Bambus
 
Resource Report
Resource Website
Bambus (RRID:SCR_005068) Bambus software resource Software for scaffolding to address some of the challenges encountered when analyzing metagenomes. Scaffolding represents the task of ordering and orienting contigs by incorporating additional information about their relative placement along the genome. While most other scaffolders are closely tied to a specific assembly program, Bambus accepts the output from most current assemblers and provides the user with great flexibility in choosing the scaffolding parameters. In particular, Bambus is able to accept contig linking data other than specified by mate-pairs. Such sources of information include alignment to a reference genome (Bambus can directly use the output of MUMmer), physical mapping data, or information about gene synteny. scaffolding is listed by: OMICtools
has parent organization: SourceForge
PMID:21926123 Open unspecified license OMICS_01432 http://sourceforge.net/apps/mediawiki/amos/index.php?title=Bambus SCR_005068 Bambus 2, Bambus 2.0 2026-08-01 12:02:53 0
University of Iowa Carver College of Medicine; Iowa; USA
 
Resource Report
Resource Website
1+ mentions
University of Iowa Carver College of Medicine; Iowa; USA (RRID:SCR_005064) UI Carver College of Medicine university Medical school of the University of Iowa, located in Iowa City, in the U.S. state of Iowa. has parent organization: University of Iowa; Iowa; USA
is parent organization of: MADS+ - discovery of differential splicing events from Affymetrix exon junction array data
is parent organization of: University of Iowa College of Medicine Department of Pharmacology
is parent organization of: University of Iowa Magnetic Resonance Research Facility
is parent organization of: University of Iowa Center for Gene Therapy Vectore Core
is parent organization of: University of Iowa Center for Gene Therapy Clinical Core
is parent organization of: University of Iowa Center for Gene Therapy Animal Model Core
is parent organization of: University of Iowa Center for Gene Therapy
is parent organization of: University of Iowa Center for Gene Therapy Comparative Pathology Core
is parent organization of: University of Iowa Center for Gene Therapy Cell Tissue Core
nlx_68753 SCR_005064 University of Iowa Carver College of Medicine, Roy J. and Lucille A. Carver College of Medicine 2026-08-01 12:02:53 1
G-BLASTN
 
Resource Report
Resource Website
G-BLASTN (RRID:SCR_005062) G-BLASTN software resource A GPU-accelerated nucleotide alignment tool based on the widely used NCBI-BLAST. It can produce exactly the same results as NCBI-BLAST, and it also has very similar user commands. It also supports a pipeline mode, which can fully utilize the GPU and CPU resources when handling a batch of medium to large sized queries. parallel computation 4, blast, alignment, nucleotide, gpu, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: NCBI BLAST
has parent organization: Hong Kong Baptist University; Hong Kong; China
has parent organization: SourceForge
Hong Kong Baptist University; Hong Kong; China FRG2/11-12/158;
NVIDIA
PMID:24463183 Free OMICS_02263, biotools:g-blastn http://sourceforge.net/projects/gblastn/, https://bio.tools/g-blastn SCR_005062 2026-08-01 12:02:45 0
Stanford Research Institute International
 
Resource Report
Resource Website
1+ mentions
Stanford Research Institute International (RRID:SCR_004926) SRI institution Independent, nonprofit research institute conducting client sponsored research and development for government agencies, commercial businesses, foundations, and other organizations. SRI also brings its innovations to the marketplace by licensing its intellectual property and creating new ventures. SRI was founded as Stanford Research Institute in 1946 by a group of West Coast industrialists and Stanford University. SRI formally separated from the University in 1970, and we changed our name to SRI International in 1977. is related to: Stanford University; Stanford; California
is parent organization of: BioCyc
is parent organization of: NIMH Toxicological Screens of Novel Ligands
is parent organization of: Project Halo
is parent organization of: EcoCyc
is parent organization of: NCANDA: Data Integration Component
is parent organization of: SRI24 Atlas: Normal Adult Brain Anatomy
is parent organization of: HumanCyc: Encyclopedia of Homo sapiens Genes and Metabolism
is parent organization of: MetaCyc
nif-0000-00235 SCR_004926 SRI International, Stanford Research Institute 2026-08-01 12:02:49 2
SLIDE
 
Resource Report
Resource Website
10+ mentions
SLIDE (RRID:SCR_005137) SLIDE software resource Software package that takes exon boundaries and RNA-Seq data as input to discern the set of mRNA isoforms that are most likely to present in an RNA-Seq sample. It is based on a linear model with a design matrix that models the sampling probability of RNA-Seq reads from different mRNA isoforms. To tackle the model unidentifiability issue, SLIDE uses a modified Lasso procedure for parameter estimation. Compared with deterministic isoform assembly algorithms (e.g., Cufflinks), SLIDE considers the stochastic aspects of RNA-Seq reads in exons from different isoforms and thus has increased power in detecting more novel isoforms. Another advantage of SLIDE is its flexibility of incorporating other transcriptomic data such as RACE, CAGE, and EST into its model to further increase isoform discovery accuracy. SLIDE can also work downstream of other RNA-Seq assembly algorithms to integrate newly discovered genes and exons. Besides isoform discovery, SLIDE sequentially uses the same linear model to estimate the abundance of discovered isoforms. is listed by: OMICtools
has parent organization: University of California at Berkeley; Berkeley; USA
NIH ;
NHGRI HG004695;
NHGRI HG005639;
NEI EY019094
PMID:22135461 OMICS_01291 SCR_005137 sparse linear modeling of RNA-Seq data for isoform discovery and abundance estimation 2026-08-01 12:02:49 32
VFS
 
Resource Report
Resource Website
1+ mentions
VFS (RRID:SCR_005138) VFS software resource A versatile high-throughput sequencing (HTS) tool for discovering viral integration events and reconstruct fusion transcripts at single-base resolution. It combines soft-clipping information, read-pair analysis, and targeted de novo assembly to discover and annotate viral-human fusion events. A simple yet effective empirical statistical model is used to evaluate the quality of fusion breakpoints. Minimal user defined parameters are required. ubuntu, debian, high-throughput sequencing, virus, reconstruct, fusion transcript, transcript, integration, fusion, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
has parent organization: Chinese University of Hong Kong; Hong Kong; China
PMID:23314323 GNU General Public License, v3 OMICS_00224, biotools:viralfusionseq https://bio.tools/viralfusionseq SCR_005138 ViralFusionSeq, ViralFusionSeq (VFS) 2026-08-01 12:02:56 1
RetroSeq
 
Resource Report
Resource Website
10+ mentions
RetroSeq (RRID:SCR_005133) RetroSeq software resource A tool for discovery and genotyping of transposable element variants (TEVs) (also known as mobile element insertions) from next-gen sequencing reads aligned to a reference genome in BAM format. The goal is to call TEVs that are not present in the reference genome but present in the sample that has been sequenced. It should be noted that RetroSeq can be used to locate any class of viral insertion in any species where whole-genome sequencing data with a suitable reference genome is available. RetroSeq is a two phase process, the first being the read pair discovery phase where discorandant mate pairs are detected and assigned to a TE class (Alu, SINE, LINE, etc.) by using either the annotated TE elements in the reference and/or aligned with Exonerate to the supplied library of viral sequences. mobile element insertion, next-gen sequencing, bam, transposable element, genome, sequence is listed by: OMICtools
has parent organization: Wellcome Trust Sanger Institute; Hinxton; United Kingdom
PMID:23233656 Acknowledgement requested, Open unspecified license OMICS_11232, OMICS_00120 SCR_005133 2026-08-01 12:02:55 45
Cloudbreak
 
Resource Report
Resource Website
Cloudbreak (RRID:SCR_005097) software resource Software providing a Hadoop-based genomic structural variation (SV) caller for Illumina paired-end DNA sequencing data. It contains a full pipeline for aligning data in the form of FASTQ files using alignment pipelines that generate many possible mappings for every read, in the Hadoop framework. It then contains Hadoop jobs for computing genomic features from the alignments, and for calling insertion and deletion variants from those features. illumina, mapreduce, insertion, deletion, genomic is listed by: OMICtools OMICS_04078 SCR_005097 2026-08-01 12:02:49 0

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