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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
Hadoop-BAM
 
Resource Report
Resource Website
1+ mentions
Hadoop-BAM (RRID:SCR_005516) Hadoop-BAM software library, software toolkit, software resource A Java library for the manipulation of files in common bioinformatics formats using the Hadoop MapReduce framework with the Picard SAM JDK, and command line tools similar to SAMtools. The file formats currently supported are BAM, SAM, FASTQ, FASTA, QSEQ, BCF, and VCF. mapreduce/hadoop, java, next generation sequencing data, cloud is listed by: OMICtools
has parent organization: SourceForge
PMID:22302568 MIT License OMICS_01051 SCR_005516 2026-08-06 09:26:21 7
MetAssign
 
Resource Report
Resource Website
1+ mentions
MetAssign (RRID:SCR_000092) standalone software, software application, software resource Software that combines information from the mass-to-charge ratio, retention time and intensity of each peak, together with a model of the inter-peak dependency structure, to increase the accuracy of peak annotation. The software has been implemented as part of the mzMatch metabolomics analysis pipeline, which is available for download. peak annotation, peaks probabilistic identifications, is listed by: OMICtools
is listed by: SourceForge
has parent organization: University of Glasgow; Glasgow; United Kingdom
PMID:24916385 Free, Available for download, Freely available OMICS_04679 http://mzmatch.sourceforge.net/ SCR_000092 2026-08-06 09:25:07 1
(at)Note
 
Resource Report
Resource Website
1+ mentions
(at)Note (RRID:SCR_005342) (at)Note text-mining software, software application, software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented September 18, 2017. Text Mining platform that copes with major Information Retrieval and Information Extraction tasks and promotes multi-disciplinary research. It aims to provide support to three different usage roles: biologists, text miners and application developers. The workbench supports the retrieval, processing and annotation of documents as well as their analysis at different levels. java, java swt, text, mining is listed by: OMICtools
has parent organization: SourceForge
has parent organization: University of Minho; Braga; Portugal
PMID:19393341 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_01167 SCR_005342 (at)Note2 - A workbench for Biomedical Text Mining 2026-08-06 09:26:19 2
ALCHEMY
 
Resource Report
Resource Website
1+ mentions
ALCHEMY (RRID:SCR_005761) ALCHEMY source code, software resource ALCHEMY is a genotype calling algorithm for Affymetrix and Illumina products which is not based on clustering methods. Features include explicit handling of reduced heterozygosity due to inbreeding and accurate results with small sample sizes. ALCHEMY is a method for automated calling of diploid genotypes from raw intensity data produced by various high-throughput multiplexed SNP genotyping methods. It has been developed for and tested on Affymetrix GeneChip Arrays, Illumina GoldenGate, and Illumina Infinium based assays. Primary motivations for ALCHEMY''s development was the lack of available genotype calling methods which can perform well in the absence of heterozygous samples (due to panels of inbred lines being genotyped) or provide accurate calls with small sample batches. ALCHEMY differs from other genotype calling methods in that genotype inference is based on a parametric Bayesian model of the raw intensity data rather than a generalized clustering approach and the model incorporates population genetic principles such as Hardy-Weinberg equilibrium adjusted for inbreeding levels. ALCHEMY can simultaneously estimate individual sample inbreeding coefficients from the data and use them to improve statistical inference of diploid genotypes at individual SNPs. The main documentation for ALCHEMY is maintained on the sourceforge-hosted MediaWiki system. Features * Population genetic model based SNP genotype calling * Simultaneous estimation of per-sample inbreeding coefficients, allele frequencies, and genotypes * Bayesian model provides posterior probabilities of genotype correctness as quality measures * Growing number of scripts and supporting programs for validation of genotypes against control data and output reformating needs * Multithreaded program for parallel execution on multi-CPU/core systems * Non-clustering based methods can handle small sample sets for empirical optimization of sample preparation techniques and accurate calling of SNPs missing genotype classes ALCHEMY is written in C and developed on the GNU/Linux platform. It should compile on any current GNU/Linux distribution with the development packages for the GNU Scientific Library (gsl) and other development packages for standard system libraries. It may also compile and run on Mac OS X if gsl is installed. diploid, genotype, snp, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: SourceForge
has parent organization: Cornell University; New York; USA
NSF 0606461 PMID:20926420 GNU General Public License biotools:alchemy, nlx_149227 https://bio.tools/alchemy SCR_005761 ALCHEMY - An automated population genetic model driven SNP genotype calling method 2026-08-06 09:26:29 5
OWL API
 
Resource Report
Resource Website
10+ mentions
OWL API (RRID:SCR_005734) OWL API source code, software resource The OWL API is a Java API and reference implementation for creating, manipulating and serializing OWL Ontologies. The latest version of the API is focused towards OWL 2. The OWLAPI underpins ontology browsing and editing tools and platforms such as SWOOP and Protege4. Note that this API, or any other OWL-based API, can be used without an integrated OWL parser if you download a pre-converted OWL file generated from OBO. See OBO Ontologies List for all OBO ontologies converted to OWL (we do not list the full complement of OWL-based APIs here, only those of direct relevance to GO). The OWL API includes the following components: * An API for OWL 2 and an efficient in-memory reference implementation * RDF/XML parser and writer * OWL/XML parser and writer * OWL Functional Syntax parser and writer * Turtle parser and writer * KRSS parser * OBO Flat file format parser * Reasoner interfaces for working with reasoners such as FaCT++, HermiT, Pellet and Racer Platform: Windows compatible, Mac OS X compatible, Linux compatible, Unix compatible ontology, owl, api, java, software library, parser, writer is listed by: Gene Ontology Tools
is related to: Gene Ontology
has parent organization: University of Manchester; Manchester; United Kingdom
has parent organization: SourceForge
Open unspecified license - Free for academic use; available under either the LGPL or Apache Licenses nlx_149195 SCR_005734 The OWL API, OWLAPI 2026-08-06 09:26:27 15
Neurofitter
 
Resource Report
Resource Website
1+ mentions
Neurofitter (RRID:SCR_005843) Neurofitter source code, software resource Neurofitter is software for parameter tuning of electrophysiological neuron models. It automatically searches for sets of parameters of neuron models that best fit available experimental data, and therefore acts as an interface between neuron simulators, like Neuron or Genesis, and optimization algorithms, like Particle Swarm Optimization, Evolutionary Strategies, etc. neuron, parameter, tuning, electrophysiology, model, neuron simulator, neuron model has parent organization: SourceForge
has parent organization: University of Antwerp; Antwerp; Belgium
has parent organization: Brandeis University; Massachusetts; USA
has parent organization: Okinawa Institute of Science and Technology
Okinawa Institute of Science and Technology PMID:18974796 GNU General Public License, v2 nlx_149366 SCR_005843 2026-08-06 09:26:25 1
OrChem
 
Resource Report
Resource Website
1+ mentions
OrChem (RRID:SCR_008865) OrChem source code, software resource OrChem is an extension for the Oracle 11G database that adds registration and indexing of chemical structures to support fast substructure and similarity searching. The cheminformatics functionality is provided by the Chemistry Development Kit. OrChem provides similarity searching with response times in the order of seconds for databases with millions of compounds, depending on a given similarity cut-off. For substructure searching, it can make use of multiple processor cores on today''s powerful database servers to provide fast response times in equally large data sets. OrChem is an Oracle chemistry plug-in using the Chemistry Development Kit (CDK). The CDK is an open source Java library for Chemoinformatics and Bioinformatics. OrChem is maintained by the chemoinformatics and metabolism team of the European Bioinformatics Institute. Oracle Data cartridges extend the capabilities of the Oracle server. For chemistry various commercial cartridges exist that facilitate searching and analyzing chemical data. OrChem also provides functionality like this, but is not a cartridge. It doesn''t need Oracle''s extensibility architecture because its Java components run as Java stored procedures inside the Oracle standard JVM (Aurora). OrChem is suitable for Oracle 11G and onwards. Starting with Oracle 11g release 1 (11.1) there is a just-in-time(JIT) compiler for Oracle JVM environment. A JIT compiler for Oracle JVM enables much faster execution because it manages the invalidation, recompilation, and storage of code without an external mechanism. This new Oracle feature makes Java classes perform better than before. oracle, chemistry, cdk, similarity search, chemical structure, cheminformatics, bioinformatics, plugin is listed by: 3DVC
has parent organization: SourceForge
has parent organization: European Bioinformatics Institute
PMID:20298521 GNU Lesser General Public License nlx_149252 SCR_008865 2026-08-06 09:27:13 1
iso2mesh
 
Resource Report
Resource Website
10+ mentions
iso2mesh (RRID:SCR_013202) iso2mesh software application, software toolkit, software resource A Matlab / Octave-based mesh generation toolbox designed for easy creation of high quality surface and tetrahedral meshes from 3D volumetric images. It contains a rich set of mesh processing scripts/programs, functioning independently or interfacing with external free meshing utilities. Iso2mesh toolbox can operate directly on 3D binary, segmented or gray-scale images, such as those from MRI or CT scans, making it particularly suitable for multi-modality medical imaging data analysis or multi-physics modeling. matlab, mesh generation, modeling, magnetic resonance, optical imaging, os independent, mri, computed tomography, octave is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
has parent organization: SourceForge
GNU General Public License nlx_155855 http://www.nitrc.org/projects/iso2mesh SCR_013202 2026-08-06 09:28:06 25
BamView
 
Resource Report
Resource Website
10+ mentions
BamView (RRID:SCR_004207) BamView source code, software resource A free interactive display of read alignments in BAM data files that can be launched with Java Web Start or downloaded. This interactive Java application for visualizing the large amounts of data stored for sequence reads which are aligned against a reference genome sequence can be used in a number of contexts including SNP calling and structural annotation. It has been integrated into Artemis so that the reads can be viewed in the context of the nucleotide sequence and genomic features. The source code is available as part of the Artemis code which can be downloaded from GitHub. bam, next-generation sequencing, java, snp calling, structural annotation, macosx, unix, windows, visualize, analyze, sequence read, reference sequence, single nucleotide polymorphism, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: SourceForge
has parent organization: Wellcome Trust Sanger Institute; Hinxton; United Kingdom
PMID:22253280
PMID:20071372
GNU General Public License biotools:bamview, OMICS_00878, nlx_22933 https://bio.tools/bamview SCR_004207 2026-08-06 09:26:03 21
MUMmerGPU
 
Resource Report
Resource Website
1+ mentions
MUMmerGPU (RRID:SCR_001200) MUMmerGPU software application, data processing software, software resource Software tool as high throughput DNA sequence alignment program that runs on nVidia G80-class GPUs. Aligns sequences in parallel on video card to accelerate widely used serial CPU program MUMmer. parallel computation 4, high-throughput sequencing, sequence alignment, dna, graphics processing unit is listed by: OMICtools
is related to: MUMmer
has parent organization: SourceForge
has parent organization: University of Maryland; Maryland; USA
NLM R01 LM006845;
NIGMS R01 GM083873
PMID:20161021 Free, Available for download, Freely available OMICS_02151 SCR_001200 High-throughput sequence alignment using Graphics Processing Units 2026-08-06 09:25:20 5
skewer
 
Resource Report
Resource Website
10+ mentions
skewer (RRID:SCR_001151) skewer software application, data processing software, software resource Software program for adapter trimming that is specially designed for processing Illumina paired-end sequences. illumina, unix/linux, c++, adapter trimming, paired-end, sequence, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
PMID:24925680 Free, Available for download, Freely available OMICS_02106, biotools:skewer https://bio.tools/skewer, https://sources.debian.org/src/skewer/, https://github.com/relipmoc/skewer SCR_001151 skewer - A fast and sensitive adapter trimmer for illumina paired-end sequences 2026-08-06 09:25:20 11
SCRalyze
 
Resource Report
Resource Website
10+ mentions
SCRalyze (RRID:SCR_002542) SCRalyze data analysis software, software application, software resource, data processing software A powerful software for model-based analysis of peripheral psychophysiology (e.g. skin conductance, heart rate, pupil size etc.). General linear modelling and dynamic causal modelling of these signals provide for inference on neural states/processes. SCRalyze includes flexible data import and display, statistical inference and results display and export. Easy programming of add-ons for new data formats, signal channels, and models. eeg, meg, electrocorticography, matlab, modeling, os independent, quantification, time domain analysis is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
has parent organization: SourceForge
Free, Available for download, Freely available nlx_155950 http://www.nitrc.org/projects/scralyze SCR_002542 SCRalyze - A matlab environment for model-based psychophysiology 2026-08-06 09:25:39 17
NIDB - Neuroinformatics Database
 
Resource Report
Resource Website
1+ mentions
NIDB - Neuroinformatics Database (RRID:SCR_002488) NIDB software resource, data management software, data or information resource, software application, database Neuroimaging database designed to allow simple importing, searching, and sharing of imaging data. NIDB also provides automated pipelining with importing of results back into NIDB which can be searched along with imaging meta data. connectome file format, clinical neuroinformatics, computational neuroscience, computed tomography, imaging genomics, interfile, javascript, neuroimaging is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
has parent organization: SourceForge
PMID:25888923 Free, Available for download, Freely available nlx_155882 http://www.nitrc.org/projects/nidb http://nidb.sourceforge.net/ SCR_002488 Neuroinformatics Database 2026-08-06 09:25:39 2
Dissect
 
Resource Report
Resource Website
Dissect (RRID:SCR_000058) Dissect software resource, alignment software, image analysis software, data processing software, software application THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 31,2025. Software transcriptome-to-genome alignment tool, which can identify and characterize transcriptomic events such as duplications, inversions, rearrangements and fusions. Structural events containing transcripts, transcriptome-to-genome alignment, identify and characterize transcriptomic events, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: SourceForge
has parent organization: Simon Fraser University; British Columbia; Canada
PMID:22689759 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_01346, biotools:dissect https://bio.tools/dissect SCR_000058 Dissect: DIScovery of Structural Events Containing Transcripts, DIScovery of Structural Events Containing Transcripts 2026-08-06 09:25:06 0
ECHO
 
Resource Report
Resource Website
100+ mentions
ECHO (RRID:SCR_011851) ECHO sequence analysis software, software resource, algorithm resource, data analysis software, data processing software, software application Error correction algorithm designed for short-reads from next-generation sequencing platforms such as Illumina''s Genome Analyzer II. error correction, rnaseq, rna sequence, short-read, next-generation sequencing, ngs, illumina, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
PMID:21482625
DOI:10.1101/gr.111351.110
Free, Available for download biotools:echo, OMICS_01102 https://bio.tools/echo, https://sources.debian.org/src/uc-echo/ SCR_011851 ECHO: A reference-free short-read error correction algorithm 2026-08-06 09:27:50 310
BWA
 
Resource Report
Resource Website
1000+ mentions
BWA (RRID:SCR_010910) BWA sequence analysis software, software resource, image analysis software, alignment software, data analysis software, data processing software, software application Software for aligning sequencing reads against large reference genome. Consists of three algorithms: BWA-backtrack, BWA-SW and BWA-MEM. First for sequence reads up to 100bp, and other two for longer sequences ranged from 70bp to 1Mbp. sequence, alignment, reference, genome, human, short, long, read, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
is related to: shovill
is related to: Proovread
is related to: BWA-MEM2
has parent organization: SourceForge
is required by: RelocaTE
PMID:19451168
PMID:20080505
DOI:10.1093/bioinformatics/btp324
Free, Available for download, Freely available SCR_015853, biotools:bwa-sw, OMICS_00654 https://sourceforge.net/projects/bio-bwa/files/, https://bio.tools/bwa-sw, https://sources.debian.org/src/bwa/ SCR_010910 Burrows-Wheeler Aligner (BWA), Burrows-Wheeler Aligner 2026-08-06 09:27:40 2291
TagCleaner
 
Resource Report
Resource Website
50+ mentions
TagCleaner (RRID:SCR_011846) standalone software, web application, software application, software resource A software tool which can automatically detect and efficiently remove tag sequences from genomic and metagenomic datasets. tag sequence, standalone software, web application, microbiome, genomic, metagenomic, datasets is listed by: OMICtools
is listed by: Human Microbiome Project
has parent organization: SourceForge
Available for download OMICS_01094 SCR_011846 2026-08-06 09:27:50 63
Multivariate Analysis of Transcript Splicing
 
Resource Report
Resource Website
100+ mentions
Multivariate Analysis of Transcript Splicing (RRID:SCR_013049) MATS data analysis software, software application, software resource, data processing software Software tool to detect differential alternative splicing events from RNA-Seq data. Calculates P value and false discovery rate that difference in isoform ratio of gene between two conditions exceeds given user defined threshold. Can automatically detect and analyze alternative splicing events corresponding to all major types of alternative splicing patterns. Handles replicate RNA-Seq data from both paired and unpaired study design. Differential alternative splicing events, splicing events calculation, RNA-Seq data, gene isoform ratio, alternative splicing patterns, patterns detection, patterns analysis, replicate RNA-Seq data is listed by: OMICtools
is listed by: SourceForge
has parent organization: Childrens Hospital of Philadelphia - Research Institute; Pennsylvania; USA
Free, Available for download, Freely available OMICS_01336, SCR_020941 SCR_013049 RNAseq MATS, RMATS, rMATS, MATS, RNA MATS 2026-08-06 09:28:03 192
Neuroimaging in Python
 
Resource Report
Resource Website
10+ mentions
Neuroimaging in Python (RRID:SCR_013141) NIPY, software resource, software development tool, software development environment, data or information resource, portal, software application, community building portal Community site to make brain imaging research easier that aims to build software that is clearly written, clearly explained, a good fit for the underlying ideas, and a natural home for collaboration. brain, imaging, neuroimaging, analysis, python, fmri, fmri analysis, magnetic resonance is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is related to: Python Programming Language
has parent organization: SourceForge
has parent organization: University of California at Berkeley; Berkeley; USA
has parent organization: Massachusetts Institute of Technology; Massachusetts; USA;
is parent organization of: Dipy
is parent organization of: NiLearn
is parent organization of: NIPY
is parent organization of: NiBabel
is parent organization of: Nipype
is parent organization of: Nitime
NIMH 5R01MH081909-02;
NIBIB 1R03EB008673-01
PMID:21897815 Revised BSD license nlx_149365 http://www.nitrc.org/projects/nipy-community http://www.nitrc.org/projects/nipype SCR_013141 NIPY Community 2026-08-06 09:28:04 24
SPInDel
 
Resource Report
Resource Website
1+ mentions
SPInDel (RRID:SCR_004509) SPInDel data set, data or information resource, software resource A multifunctional workbench for species identification using insertion/deletion variants. The SPInDel workbench provides a step-by-step environment for the alignment of target sequences, selection of informative hypervariable regions, design of PCR primers and the statistical validation of the species-identification process. It includes a large dataset comprising nearly 1,800 numeric profiles for the identification of eukaryotic, prokaryotic and viral species. virus, indel, dna barcoding, alignment, nucleotide sequence, visualization, conserved region, pcr primer, phylogenetic, variant is listed by: OMICtools
has parent organization: University of Porto; Porto; Portugal
has parent organization: SourceForge
PMID:22978681
PMID:20923781
Acknowledgement requested, Free, Public OMICS_01496 SCR_004509 SPecies Identification by Insertions/Deletions, SPInDel - Species identification by insertions/deletions 2026-08-06 09:26:09 2

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