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Cellosaurus is database indexing available cell lines from various collections: American Type Culture Collection (ATCC), Bioresource Collection and Research Center, Taiwan (BCRC), Banco de Células do Rio de Janeiro (BCRJ), CellBank Australia (CBA), Collection of Cell Lines in Veterinary Medicine (CCLV), Cell Lines Service (CLS), Coriell, Drosophila Genomics Resource Center (DGRC), Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSMZ), European Bank for induced pluripotent Stem Cells (EBiSC), European Collection of Authenticated Cell Cultures (ECACC), Interlab Cell Line Collection (ICLC), Institute for Fermentation Osaka (IFO), Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna (IZSLER) biobank, Japanese Collection of Research Bioresources (JCRB) Cell Bank, Kunming Cell Bank of Type Culture Collection (KCB), Korean Cell Line Bank (KCLB), Millipore, National Cell Bank of Iran (NCBI_Iran), National Cancer Institute - Developmental Therapeutics Program (NCI-DTP), NINDS Human Cell and Data Repository (NHCDR), NIH AIDS Reagent Program (NIH-ARP), NISES, RIKEN Bioresource Center Cell Bank (RCB), Royan Stem Cell Bank (RSCB), Tick Cell Biobank (TCB), Tohoku University cell line catalog (TKG), and Ximbio.
https://web.expasy.org/cellosaurus/CVCL_5438
Organism: Mus musculus (Mouse)
Disease:
Category: Spontaneously immortalized cell line
Comments: Characteristics: Exhibits poor osteoblast differentiation after growth in ascorbic acid. Does not form a mineralized extracellular matrix (ATCC=CRL-2595).
Proper citation: CLS Cat# 305186, RRID:CVCL_5438 Copy
Misidentified Misidentified Possibly Discontinued Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_4540
Organism: Chlorocebus pygerythrus (Vervet monkey)
Disease:
Category: Spontaneously immortalized cell line
Comments: Virology: Highly susceptible to infection by porcine reproductive and respiratory syndrome virus (PRRSV)., Problematic cell line: Misidentified. Parent cell line (MA-104) has been shown to be from African Green monkey instead of Rhesus macaque.., Group: Patented cell line., Group: Non-human primate cell line.
Proper citation: CLS Cat# 305006, RRID:CVCL_4540 Copy
https://web.expasy.org/cellosaurus/CVCL_5437
Organism: Mus musculus (Mouse)
Disease:
Category: Spontaneously immortalized cell line
Comments: Characteristics: Exhibits high levels of osteoblast differentiation after growth in ascorbic acid and 3 to 4 mM inorganic phosphate. Forms a well mineralized extracellular matrix (ECM) after 10 days (ATCC=CRL-2594).
Proper citation: CLS Cat# 305185, RRID:CVCL_5437 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_0593
Organism: Neovison vison (American mink)
Disease:
Category: Spontaneously immortalized cell line
Comments: Virology: Susceptible to infection by SARS coronavirus (SARS-CoV) (PubMed=15731278)., Virology: Susceptible to infection and replication of influenza A and B viruses (PubMed=9817906)., Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982).
Proper citation: CLS Cat# 305192, RRID:CVCL_0593 Copy
https://web.expasy.org/cellosaurus/CVCL_3544
Organism: Mus musculus (Mouse)
Disease: Mouse Leydig cell tumor
Category: Cancer cell line
Comments:
Proper citation: CLS Cat# 305175, RRID:CVCL_3544 Copy
https://web.expasy.org/cellosaurus/CVCL_4996
Organism: Homo sapiens (Human)
Disease: Human papillomavirus-related cervical squamous cell carcinoma
Category: Cancer cell line
Comments: Virology: Contains a partial HPV45 genome., Population: Caucasian., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: CLS Cat# 305115, RRID:CVCL_4996 Copy
https://web.expasy.org/cellosaurus/CVCL_3411
Organism: Mus musculus (Mouse)
Disease: Mouse multiple myeloma
Category: Cancer cell line
Comments: Part of: Tumor Immunology Bank (TIB) collection from Salk (transferred to ATCC in 1981)., Group: Hybridoma fusion partner cell line.
Proper citation: CLS Cat# 305171, RRID:CVCL_3411 Copy
https://web.expasy.org/cellosaurus/CVCL_B459
Organism: Mus musculus (Mouse)
Disease: Carcinoma of the mouse prostate gland
Category: Cancer cell line
Comments:
Proper citation: CLS Cat# 305168, RRID:CVCL_B459 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_4U18
Organism: Homo sapiens (Human)
Disease:
Category: Hybrid cell line
Comments: Characteristics: Can differentiate when cultured in mitogen-free medium. The cells may be used to study developmental regulation of cardiomyocytes (Millipore=SCC109)., Characteristics: Hybrid of adult ventricular cardiomiocytes with a SV40 transformed, uridine auxotroph human fibroblast cell line devoid of mitochondrial DNA (PubMed=15913645)., Group: Patented cell line.
Proper citation: CLS Cat# 305215, RRID:CVCL_4U18 Copy
https://web.expasy.org/cellosaurus/CVCL_6552
Organism: Mus musculus (Mouse)
Disease:
Category: Transformed cell line
Comments:
Proper citation: CLS Cat# 305191, RRID:CVCL_6552 Copy
https://web.expasy.org/cellosaurus/CVCL_B288
Organism: Mus musculus (Mouse)
Disease: Mouse colon adenocarcinoma
Category: Cancer cell line
Comments: Caution: The authors of PubMed=25434994 indicate that they have sequenced the mitochondrial genome of the 'rat' cell line MCA38. Their submitted DNA sequence (KM820832.1) is indeed a rat sequence but is labelled as originating from 'rat isolate 406'., Miscellaneous: Comparative analysis of MC38 cells obtained from Kerafast (MC38-K) and from Leiden University Medical Center (MC38-L) shows major differences in term of mutations and mRNA expression (PubMed=36969213).
Proper citation: CLS Cat# 305223, RRID:CVCL_B288 Copy
https://web.expasy.org/cellosaurus/CVCL_3855
Organism: Mus musculus (Mouse)
Disease:
Category: Transformed cell line
Comments:
Proper citation: CLS Cat# 300487, RRID:CVCL_3855 Copy
https://web.expasy.org/cellosaurus/CVCL_5J48
Organism: Mus musculus (Mouse)
Disease: Mouse gastric carcinoma
Category: Cancer cell line
Comments:
Proper citation: CLS Cat# 300652, RRID:CVCL_5J48 Copy
https://web.expasy.org/cellosaurus/CVCL_B063
Organism: Mus musculus (Mouse)
Disease:
Category: Spontaneously immortalized cell line
Comments:
Proper citation: CLS Cat# 305182, RRID:CVCL_B063 Copy
https://web.expasy.org/cellosaurus/CVCL_2665
Organism: Mus musculus (Mouse)
Disease:
Category: Hybridoma
Comments: Anecdotal: OKT3 was the first monoclonal antibody to be approved for clinical use in humans., Biotechnology: The monoclonal antibody produced by this hybridoma was used to prepare the humanized teplizumab (MGA031) therapeutic antibody., Biotechnology: The monoclonal antibody produced by this hybridoma was used as an immunosuppressant drug under the name Muromonab-CD3 (Orthoclone OKT3)., Group: Patented cell line.
Proper citation: CLS Cat# 300499, RRID:CVCL_2665 Copy
https://web.expasy.org/cellosaurus/CVCL_2664
Organism: Mus musculus (Mouse)
Disease:
Category: Hybridoma
Comments: Group: Patented cell line.
Proper citation: CLS Cat# 300500, RRID:CVCL_2664 Copy
https://web.expasy.org/cellosaurus/CVCL_5845
Organism: Mus musculus (Mouse)
Disease:
Category: Transformed cell line
Comments:
Proper citation: CLS Cat# 400100, RRID:CVCL_5845 Copy
Discontinued Possibly Discontinued Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_0347
Organism: Homo sapiens (Human)
Disease:
Category: Finite cell line
Comments: Senescence: Capable of attaining 58 population doublings before the onset of senescence (ATCC=CCL-186)., Population: Caucasian., Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982)., Part of: International Histocompatibility Workshop cell lines., Part of: ENCODE project common cell types; tier 2.
Proper citation: CLS Cat# 305216, RRID:CVCL_0347 Copy
https://web.expasy.org/cellosaurus/CVCL_G363
Organism: Mus musculus (Mouse)
Disease: Adenocarcinoma of the mouse pulmonary system
Category: Cancer cell line
Comments:
Proper citation: CLS Cat# 300472, RRID:CVCL_G363 Copy
https://web.expasy.org/cellosaurus/CVCL_1362
Organism: Homo sapiens (Human)
Disease: Hodgkin lymphoma
Category: Cancer cell line
Comments: Population: Caucasian., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: CLS Cat# 300201, RRID:CVCL_1362 Copy
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