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Cellosaurus is database indexing available cell lines from various collections: American Type Culture Collection (ATCC), Bioresource Collection and Research Center, Taiwan (BCRC), Banco de Células do Rio de Janeiro (BCRJ), CellBank Australia (CBA), Collection of Cell Lines in Veterinary Medicine (CCLV), Cell Lines Service (CLS), Coriell, Drosophila Genomics Resource Center (DGRC), Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSMZ), European Bank for induced pluripotent Stem Cells (EBiSC), European Collection of Authenticated Cell Cultures (ECACC), Interlab Cell Line Collection (ICLC), Institute for Fermentation Osaka (IFO), Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna (IZSLER) biobank, Japanese Collection of Research Bioresources (JCRB) Cell Bank, Kunming Cell Bank of Type Culture Collection (KCB), Korean Cell Line Bank (KCLB), Millipore, National Cell Bank of Iran (NCBI_Iran), National Cancer Institute - Developmental Therapeutics Program (NCI-DTP), NINDS Human Cell and Data Repository (NHCDR), NIH AIDS Reagent Program (NIH-ARP), NISES, RIKEN Bioresource Center Cell Bank (RCB), Royan Stem Cell Bank (RSCB), Tick Cell Biobank (TCB), Tohoku University cell line catalog (TKG), and Ximbio.
Discontinued
https://web.expasy.org/cellosaurus/CVCL_0358
Organism: Mus musculus (Mouse)
Disease: Mouse reticulum cell sarcoma
Category: Cancer cell line
Comments: Part of: Tumor Immunology Bank (TIB) collection from Salk (transferred to ATCC in 1981).
Proper citation: BCRC Cat# 60140, RRID:CVCL_0358 Copy
https://web.expasy.org/cellosaurus/CVCL_3530
Organism: Mus musculus (Mouse)
Disease: Malignant neoplasms of the mouse mammary gland
Category: Cancer cell line
Comments: Karyotypic information: Hypo-tetraploid karyotype with 64-66 chromosomes (PubMed=33526060).
Proper citation: BCRC Cat# 60347, RRID:CVCL_3530 Copy
https://web.expasy.org/cellosaurus/CVCL_0363
Organism: Homo sapiens (Human)
Disease: Gestational choriocarcinoma
Category: Cancer cell line
Comments: Caution: A TP53 mutation is indicated as being at p.Gln167His (c.501G>T) in PubMed=7819056 but has not been confirmed by CCLE and Cosmic-CLP., Karyotypic information: Near tetraploid karyotype (PubMed=33096371)., Characteristics: Established by serial cloning into hamster cheek pouches., Population: Caucasian., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: BCRC Cat# 60428, RRID:CVCL_0363 Copy
Discontinued Possibly Discontinued Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_0347
Organism: Homo sapiens (Human)
Disease:
Category: Finite cell line
Comments: Senescence: Capable of attaining 58 population doublings before the onset of senescence (ATCC=CCL-186)., Population: Caucasian., Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982)., Part of: International Histocompatibility Workshop cell lines., Part of: ENCODE project common cell types; tier 2.
Proper citation: BCRC Cat# 60204, RRID:CVCL_0347 Copy
Discontinued Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_0346
Organism: Homo sapiens (Human)
Disease: Neuroblastoma
Category: Cancer cell line
Comments: Characteristics: Neuroblastic type (N-type)., Population: Caucasian., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: BCRC Cat# 60014, RRID:CVCL_0346 Copy
https://web.expasy.org/cellosaurus/CVCL_3752
Organism: Mus musculus (Mouse)
Disease: Mouse fibrosarcoma
Category: Cancer cell line
Comments:
Proper citation: BCRC Cat# 60560, RRID:CVCL_3752 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_0440
Organism: Homo sapiens (Human)
Disease:
Category: Finite cell line
Comments: Virology: Not susceptible to infection by SARS coronavirus 2 (SARS-CoV-2) (COVID-19) (PubMed=33389257)., Senescence: Capable of attaining 42-46 population doublings before the onset of senescence (ATCC=CCL-171). Senesces at 26 PDL (PubMed=17395773)., Biotechnology: Used for the production of the live zoster vaccine (Trade name: Zostavax)., Biotechnology: Used for the production of the live varicella virus vaccine (Trade name: Varivax)., Biotechnology: Used for the production of the Hepatitis A vaccines Avaxim, Epaxal, Havrix and Vaqta., Biotechnology: Used for the production of the Human Diploid Cell Vaccine (HDCV) against rabies (Trade name: Imovax Rabies)., Group: Vaccine production cell line.
Proper citation: BCRC Cat# 60023, RRID:CVCL_0440 Copy
https://web.expasy.org/cellosaurus/CVCL_3420
Organism: Mus musculus (Mouse)
Disease:
Category: Spontaneously immortalized cell line
Comments:
Proper citation: BCRC Cat# 60003, RRID:CVCL_3420 Copy
https://web.expasy.org/cellosaurus/CVCL_5368
Organism: Mus musculus (Mouse)
Disease:
Category: Transformed cell line
Comments:
Proper citation: BCRC Cat# 60366, RRID:CVCL_5368 Copy
https://web.expasy.org/cellosaurus/CVCL_4393
Organism: Mus musculus (Mouse)
Disease:
Category: Transformed cell line
Comments:
Proper citation: BCRC Cat# 60220, RRID:CVCL_4393 Copy
https://web.expasy.org/cellosaurus/CVCL_3794
Organism: Bos taurus (Bovine)
Disease:
Category: Finite cell line
Comments: Virology: Persistently infected by bovine viral diarrhea virus (BVDV) (PubMed=7989438)., Senescence: Capable of 60-70 PDL (ATCC=CRL-1796)., Characteristics: Responsive to ACTH and other steroidogenic agents (ATCC=CRL-1796).
Proper citation: BCRC Cat# 60336, RRID:CVCL_3794 Copy
https://web.expasy.org/cellosaurus/CVCL_6449
Organism: Mus musculus (Mouse)
Disease:
Category: Finite cell line
Comments: Characteristics: Will differentiate into myotubes with serum deprivation (ATCC=CRL-2174).
Proper citation: BCRC Cat# 60512, RRID:CVCL_6449 Copy
https://web.expasy.org/cellosaurus/CVCL_2199
Organism: Mus musculus (Mouse)
Disease: Mouse multiple myeloma
Category: Cancer cell line
Comments: Group: Hybridoma fusion partner cell line.
Proper citation: BCRC Cat# 60034, RRID:CVCL_2199 Copy
https://web.expasy.org/cellosaurus/CVCL_4694
Organism: Rattus norvegicus (Rat)
Disease:
Category: Spontaneously immortalized cell line
Comments:
Proper citation: BCRC Cat# 60507, RRID:CVCL_4694 Copy
https://web.expasy.org/cellosaurus/CVCL_1920
Organism: Oncorhynchus mykiss (Rainbow trout)
Disease:
Category: Spontaneously immortalized cell line
Comments: Anecdotal: First fish cell line, established in 1962., Group: Fish cell line.
Proper citation: BCRC Cat# 60445, RRID:CVCL_1920 Copy
https://web.expasy.org/cellosaurus/CVCL_6518
Organism: Mus musculus (Mouse)
Disease: Mouse lymphoma
Category: Cancer cell line
Comments: Part of: Tumor Immunology Bank (TIB) collection from Salk (transferred to ATCC in 1981).
Proper citation: BCRC Cat# 60227, RRID:CVCL_6518 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_0059
Organism: Chlorocebus sabaeus (Green monkey)
Disease:
Category: Spontaneously immortalized cell line
Comments: Anecdotal: Verda reno means green kidney in Esperanto and Vero means truth also in Esperanto., Virology: Susceptible to infection by SARS coronavirus 2 (SARS-CoV-2) (COVID-19). But Vero C1008 (often known as Vero E6) (Cellosaurus=CVCL_0574) seems to be more appropriate for amplification and quantification (PubMed=32511316; PubMed=33389257)., Virology: Susceptible to infection by SARS coronavirus (SARS-CoV). Produces a lytic infection (PubMed=15731278; PubMed=16494729)., Biotechnology: Used for the production of the Sinovax SARS-CoV-2 (COVID-19) vaccine (Trade name: CoronaVac; also known as PiCoVacc) (DrugBank=DB15806). The cell line is used to produces the inactivated SARS-CoV-2 virus strain CN02 (PubMed=32376603)., Biotechnology: Used for the production of the Bharat Biotech SARS-CoV-2 (COVID-19) vaccine (Trade name: Covaxin; also known as BBV152) (DrugBank=DB15847). The cell line is used to produces a inactivated SARS-CoV-2 virus strain., Biotechnology: Used for the production of the tetravalent dengue vaccine (Trade Name: Dengvaxia)., Biotechnology: Used for the production of the live smallpox (vaccinia) vaccine (Trade name: ACAM2000)., Biotechnology: Used for the production of the live oral rotavirus vaccine (Trade Name: Rotarix)., Biotechnology: Used for the production of the Chromatographically Purified Rabies Vaccine (CPRV)., Biotechnology: Used for the production of the Purified Vero-cell Rabies Vaccine (PVRV) (Trade name: VERORAB)., Biotechnology: Used for the production of the inactivated poliovirus vaccine (Trade name: Imovax Polio)., Biotechnology: Used for the production of the Japanese encephalitis virus (JEV) vaccine (Trade name: IXIARO/JESPECT)., Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982)., Group: Vaccine production cell line., Group: Non-human primate cell line.
Proper citation: BCRC Cat# 60013, RRID:CVCL_0059 Copy
Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_Y106
Organism: Homo sapiens (Human)
Disease: Medulloblastoma
Category: Cancer cell line
Comments:
Proper citation: BCRC Cat# 60375, RRID:CVCL_Y106 Copy
https://web.expasy.org/cellosaurus/CVCL_3622
Organism: Mus musculus (Mouse)
Disease: Mouse leukemia
Category: Cancer cell line
Comments: Part of: Tumor Immunology Bank (TIB) collection from Salk (transferred to ATCC in 1981).
Proper citation: BCRC Cat# 60176, RRID:CVCL_3622 Copy
https://web.expasy.org/cellosaurus/CVCL_6458
Organism: Mus musculus (Mouse)
Disease:
Category: Transformed cell line
Comments: Characteristics: At the permissive temperature (33 Celsius) proliferates. Does not proliferate at the restrictive temperature (37 Celsius).
Proper citation: BCRC Cat# 60550, RRID:CVCL_6458 Copy
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