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Cellosaurus is database indexing available cell lines from various collections: American Type Culture Collection (ATCC), Bioresource Collection and Research Center, Taiwan (BCRC), Banco de Células do Rio de Janeiro (BCRJ), CellBank Australia (CBA), Collection of Cell Lines in Veterinary Medicine (CCLV), Cell Lines Service (CLS), Coriell, Drosophila Genomics Resource Center (DGRC), Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSMZ), European Bank for induced pluripotent Stem Cells (EBiSC), European Collection of Authenticated Cell Cultures (ECACC), Interlab Cell Line Collection (ICLC), Institute for Fermentation Osaka (IFO), Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna (IZSLER) biobank, Japanese Collection of Research Bioresources (JCRB) Cell Bank, Kunming Cell Bank of Type Culture Collection (KCB), Korean Cell Line Bank (KCLB), Millipore, National Cell Bank of Iran (NCBI_Iran), National Cancer Institute - Developmental Therapeutics Program (NCI-DTP), NINDS Human Cell and Data Repository (NHCDR), NIH AIDS Reagent Program (NIH-ARP), NISES, RIKEN Bioresource Center Cell Bank (RCB), Royan Stem Cell Bank (RSCB), Tick Cell Biobank (TCB), Tohoku University cell line catalog (TKG), and Ximbio.
https://web.expasy.org/cellosaurus/CVCL_KU56
Organism: Cricetulus griseus (Chinese hamster)
Category: Spontaneously immortalized cell line
Proper citation: DiscoverX Cat# 95-1005C2, RRID:CVCL_KU56 Copy
https://web.expasy.org/cellosaurus/CVCL_KU61
Organism: Cricetulus griseus (Chinese hamster)
Category: Spontaneously immortalized cell line
Proper citation: DiscoverX Cat# 95-1003C2, RRID:CVCL_KU61 Copy
https://web.expasy.org/cellosaurus/CVCL_KU49
Organism: Cricetulus griseus (Chinese hamster)
Category: Spontaneously immortalized cell line
Proper citation: DiscoverX Cat# 95-1023C2, RRID:CVCL_KU49 Copy
https://web.expasy.org/cellosaurus/CVCL_KU51
Organism: Cricetulus griseus (Chinese hamster)
Category: Spontaneously immortalized cell line
Proper citation: DiscoverX Cat# 95-1001C2, RRID:CVCL_KU51 Copy
https://web.expasy.org/cellosaurus/CVCL_KU55
Organism: Cricetulus griseus (Chinese hamster)
Category: Spontaneously immortalized cell line
Proper citation: DiscoverX Cat# 95-1006C2, RRID:CVCL_KU55 Copy
https://web.expasy.org/cellosaurus/CVCL_KU52
Organism: Cricetulus griseus (Chinese hamster)
Category: Spontaneously immortalized cell line
Proper citation: DiscoverX Cat# 95-1013C2, RRID:CVCL_KU52 Copy
https://web.expasy.org/cellosaurus/CVCL_KU59
Organism: Cricetulus griseus (Chinese hamster)
Category: Spontaneously immortalized cell line
Proper citation: DiscoverX Cat# 95-1004C2, RRID:CVCL_KU59 Copy
https://web.expasy.org/cellosaurus/CVCL_KW03
Organism: Homo sapiens (Human)
Category: Transformed cell line
Comments: Characteristics: InCELL Hunter cell lines express a transfected target protein fragment tagged with a beta-galactosidase fragment (enhanced ProLabel=ePL). The technology measures compound binding to an intracellular target by detecting changes in protein stability. The amount of fusion is quantified through the addition of substrate and a second enzyme fragment (Enzyme acceptor=EA).
Proper citation: DiscoverX Cat# 96-0049C1, RRID:CVCL_KW03 Copy
https://web.expasy.org/cellosaurus/CVCL_KW08
Organism: Homo sapiens (Human)
Category: Transformed cell line
Comments: Characteristics: InCELL Hunter cell lines express a transfected target protein fragment tagged with a beta-galactosidase fragment (enhanced ProLabel=ePL). The technology measures compound binding to an intracellular target by detecting changes in protein stability. The amount of fusion is quantified through the addition of substrate and a second enzyme fragment (Enzyme acceptor=EA).
Proper citation: DiscoverX Cat# 96-0046C1, RRID:CVCL_KW08 Copy
https://web.expasy.org/cellosaurus/CVCL_KW07
Organism: Homo sapiens (Human)
Category: Transformed cell line
Comments: Characteristics: InCELL Hunter cell lines express a transfected target protein fragment tagged with a beta-galactosidase fragment (enhanced ProLabel=ePL). The technology measures compound binding to an intracellular target by detecting changes in protein stability. The amount of fusion is quantified through the addition of substrate and a second enzyme fragment (Enzyme acceptor=EA).
Proper citation: DiscoverX Cat# 96-0006C1, RRID:CVCL_KW07 Copy
https://web.expasy.org/cellosaurus/CVCL_KW09
Organism: Homo sapiens (Human)
Category: Transformed cell line
Comments: Characteristics: InCELL Hunter cell lines express a transfected target protein fragment tagged with a beta-galactosidase fragment (enhanced ProLabel=ePL). The technology measures compound binding to an intracellular target by detecting changes in protein stability. The amount of fusion is quantified through the addition of substrate and a second enzyme fragment (Enzyme acceptor=EA).
Proper citation: DiscoverX Cat# 96-0060C1, RRID:CVCL_KW09 Copy
https://web.expasy.org/cellosaurus/CVCL_KZ36
Organism: Homo sapiens (Human)
Category: Transformed cell line
Comments: Characteristics: PathHunter beta-arrestin parental cell lines express a beta-arrestin tagged with a beta-galactosidase fragment (Enzyme Acceptor=EA). They can be used to introduce a GPCR tagged with another beta-galactosidase fragment (ProLink=PK).
Proper citation: DiscoverX Cat# 93-0165, RRID:CVCL_KZ36 Copy
https://web.expasy.org/cellosaurus/CVCL_KZ22
Organism: Cricetulus griseus (Chinese hamster)
Category: Spontaneously immortalized cell line
Comments: Characteristics: PathHunter beta-arrestin cell lines co-express a GPCR tagged with a beta-galactosidase fragment (ProLink=PK) and a beta-arrestin tagged with another fragment (Enzyme Acceptor=EA). Activation of the GPCR-PK induces beta-arrestin-EA recruitment and complementation of the PK and EA enzyme fragments thus resulting into a catalytically active enzyme that generate a chemiluminescent signal.
Proper citation: DiscoverX Cat# 93-0239C2, RRID:CVCL_KZ22 Copy
https://web.expasy.org/cellosaurus/CVCL_KZ40
Organism: Homo sapiens (Human)
Category: Transformed cell line
Comments: Characteristics: PathHunter beta-arrestin cell lines co-express a GPCR tagged with a beta-galactosidase fragment (ProLink=PK) and a beta-arrestin tagged with another fragment (Enzyme Acceptor=EA). Activation of the GPCR-PK induces beta-arrestin-EA recruitment and complementation of the PK and EA enzyme fragments thus resulting into a catalytically active enzyme that generate a chemiluminescent signal.
Proper citation: DiscoverX Cat# 93-0201C1, RRID:CVCL_KZ40 Copy
https://web.expasy.org/cellosaurus/CVCL_KZ53
Organism: Homo sapiens (Human)
Category: Transformed cell line
Comments: Characteristics: PathHunter beta-arrestin cell lines co-express a GPCR tagged with a beta-galactosidase fragment (ProLink=PK) and a beta-arrestin tagged with another fragment (Enzyme Acceptor=EA). Activation of the GPCR-PK induces beta-arrestin-EA recruitment and complementation of the PK and EA enzyme fragments thus resulting into a catalytically active enzyme that generate a chemiluminescent signal.
Proper citation: DiscoverX Cat# 93-0384C1A, RRID:CVCL_KZ53 Copy
https://web.expasy.org/cellosaurus/CVCL_KZ35
Organism: Homo sapiens (Human)
Category: Transformed cell line
Comments: Characteristics: PathHunter beta-arrestin parental cell lines express a beta-arrestin tagged with a beta-galactosidase fragment (Enzyme Acceptor=EA). They can be used to introduce a GPCR tagged with another beta-galactosidase fragment (ProLink=PK).
Proper citation: DiscoverX Cat# 93-0798, RRID:CVCL_KZ35 Copy
https://web.expasy.org/cellosaurus/CVCL_KZ58
Organism: Homo sapiens (Human)
Category: Transformed cell line
Comments: Characteristics: PathHunter degradation cell lines express a target protein tagged with a beta-galactosidase fragment (Enzyme Donor=ED). Pathway activation results in the degradation of the target protein. The degraded protein is detected by adding to the cell lysis buffer another beta-galactosidase fragment (Enzyme Acceptor=EA). Complementation of the ED and EA enzyme fragments result into a catalytically active enzyme that generate a chemiluminescent signal.
Proper citation: DiscoverX Cat# 93-0538C1, RRID:CVCL_KZ58 Copy
https://web.expasy.org/cellosaurus/CVCL_KZ62
Organism: Homo sapiens (Human)
Category: Transformed cell line
Comments: Characteristics: PathHunter beta-arrestin cell lines co-express a GPCR tagged with a beta-galactosidase fragment (ProLink=PK) and a beta-arrestin tagged with another fragment (Enzyme Acceptor=EA). Activation of the GPCR-PK induces beta-arrestin-EA recruitment and complementation of the PK and EA enzyme fragments thus resulting into a catalytically active enzyme that generate a chemiluminescent signal.
Proper citation: DiscoverX Cat# 93-0214C1, RRID:CVCL_KZ62 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_KZ26
Organism: Cricetulus griseus (Chinese hamster)
Category: Spontaneously immortalized cell line
Comments: Characteristics: PathHunter beta-arrestin cell lines co-express a GPCR tagged with a beta-galactosidase fragment (ProLink=PK) and a beta-arrestin tagged with another fragment (Enzyme Acceptor=EA). Activation of the GPCR-PK induces beta-arrestin-EA recruitment and complementation of the PK and EA enzyme fragments thus resulting into a catalytically active enzyme that generate a chemiluminescent signal.
Proper citation: DiscoverX Cat# 93-0958C2, RRID:CVCL_KZ26 Copy
https://web.expasy.org/cellosaurus/CVCL_KZ49
Organism: Homo sapiens (Human)
Category: Transformed cell line
Comments: Characteristics: PathHunter total GPCR internalization cell lines co-express a tagged with a beta-galactosidase fragment (ProLink=PK) and a second beta-galactosidase fragment (Enzyme Acceptor=EA) localized to the endosomes. Activation of the GPCR-PK induces internalization of the receptor in EA-tagged endosomes and complementation of the PK and EA enzyme fragments thus resulting into a catalytically active enzyme that generate a chemiluminescent signal.
Proper citation: DiscoverX Cat# 93-0820C1, RRID:CVCL_KZ49 Copy
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