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Cellosaurus is database indexing available cell lines from various collections: American Type Culture Collection (ATCC), Bioresource Collection and Research Center, Taiwan (BCRC), Banco de Células do Rio de Janeiro (BCRJ), CellBank Australia (CBA), Collection of Cell Lines in Veterinary Medicine (CCLV), Cell Lines Service (CLS), Coriell, Drosophila Genomics Resource Center (DGRC), Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSMZ), European Bank for induced pluripotent Stem Cells (EBiSC), European Collection of Authenticated Cell Cultures (ECACC), Interlab Cell Line Collection (ICLC), Institute for Fermentation Osaka (IFO), Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna (IZSLER) biobank, Japanese Collection of Research Bioresources (JCRB) Cell Bank, Kunming Cell Bank of Type Culture Collection (KCB), Korean Cell Line Bank (KCLB), Millipore, National Cell Bank of Iran (NCBI_Iran), National Cancer Institute - Developmental Therapeutics Program (NCI-DTP), NINDS Human Cell and Data Repository (NHCDR), NIH AIDS Reagent Program (NIH-ARP), NISES, RIKEN Bioresource Center Cell Bank (RCB), Royan Stem Cell Bank (RSCB), Tick Cell Biobank (TCB), Tohoku University cell line catalog (TKG), and Ximbio.
https://web.expasy.org/cellosaurus/CVCL_3305
Organism: Homo sapiens (Human)
Disease: Osteogenesis imperfecta
Category: Finite cell line
Comments:
Proper citation: ATCC Cat# CRL-1294, RRID:CVCL_3305 Copy
https://web.expasy.org/cellosaurus/CVCL_3529
Organism: Mus musculus (Mouse)
Disease: Mouse multiple myeloma
Category: Cancer cell line
Comments: Part of: Tumor Immunology Bank (TIB) collection from Salk (transferred to ATCC in 1981)., Problematic cell line: Potentially contaminated. The stock distributed by ATCC (TIB-6) has a STR profile that matches at 95% with that of BALB/3T3 clone A31 (Cellosaurus=CVCL_0184). As this is the parent cell line to a cell line J558L (Cellosaurus=CVCL_3949) which is used a fusion cell line for the production of hybridomas ICLAC is currently investigating if authentic stocks of J558 still exist..
Proper citation: ATCC Cat# TIB-6, RRID:CVCL_3529 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_U778
Organism: Homo sapiens (Human)
Disease: Ehlers-Danlos syndrome
Category: Finite cell line
Comments:
Proper citation: ATCC Cat# CRL-1380, RRID:CVCL_U778 Copy
https://web.expasy.org/cellosaurus/CVCL_G195
Organism: Mus musculus (Mouse)
Disease:
Category: Hybridoma
Comments: Group: Patented cell line.
Proper citation: ATCC Cat# HB-8298, RRID:CVCL_G195 Copy
https://web.expasy.org/cellosaurus/CVCL_3304
Organism: Homo sapiens (Human)
Disease: Ehlers-Danlos syndrome, type II
Category: Finite cell line
Comments:
Proper citation: ATCC Cat# CRL-1176, RRID:CVCL_3304 Copy
https://web.expasy.org/cellosaurus/CVCL_3319
Organism: Homo sapiens (Human)
Disease: Ehlers-Danlos syndrome, type I
Category: Finite cell line
Comments:
Proper citation: ATCC Cat# CRL-1215, RRID:CVCL_3319 Copy
https://web.expasy.org/cellosaurus/CVCL_0362
Organism: Mus musculus (Mouse)
Disease:
Category: Spontaneously immortalized cell line
Comments: Characteristics: Sensitive to promotion of transformation (P+) by phorbol esters (PubMed=6119803).
Proper citation: ATCC Cat# CRL-2010, RRID:CVCL_0362 Copy
https://web.expasy.org/cellosaurus/CVCL_0361
Organism: Mus musculus (Mouse)
Disease:
Category: Spontaneously immortalized cell line
Comments: Characteristics: Resistant to promotion of transformation (P-) by phorbol esters (PubMed=6119803).
Proper citation: ATCC Cat# CRL-2007, RRID:CVCL_0361 Copy
https://web.expasy.org/cellosaurus/CVCL_3530
Organism: Mus musculus (Mouse)
Disease: Malignant neoplasms of the mouse mammary gland
Category: Cancer cell line
Comments: Karyotypic information: Hypo-tetraploid karyotype with 64-66 chromosomes (PubMed=33526060).
Proper citation: ATCC Cat# CRL-2116, RRID:CVCL_3530 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_T280
Organism: Homo sapiens (Human)
Disease: Galactosemia
Category: Finite cell line
Comments:
Proper citation: ATCC Cat# CCL-118, RRID:CVCL_T280 Copy
https://web.expasy.org/cellosaurus/CVCL_0360
Organism: Homo sapiens (Human)
Disease: Gestational choriocarcinoma
Category: Cancer cell line
Comments: Caution: Established from the trophoblastic tumor of the placenta of a 24 year old woman, but the cell line is from the male fetus., Karyotypic information: Near triploid karyotype (PubMed=33096371)., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: ATCC Cat# HTB-144, RRID:CVCL_0360 Copy
https://web.expasy.org/cellosaurus/CVCL_3531
Organism: Rattus norvegicus (Rat)
Disease: Rat sarcoma
Category: Cancer cell line
Comments: Characteristics: Used in studies of amino acid requirements and L-asparagine metabolism (IZSLER=BS TCL 31).
Proper citation: ATCC Cat# CCL-45, RRID:CVCL_3531 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_5985
Organism: Homo sapiens (Human)
Disease: Tongue squamous cell carcinoma
Category: Cancer cell line
Comments:
Proper citation: ATCC Cat# CRL-2718, RRID:CVCL_5985 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_5986
Organism: Homo sapiens (Human)
Disease: Laryngeal squamous cell carcinoma
Category: Cancer cell line
Comments: Population: Caucasian., Part of: MD Anderson Cell Lines Project., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: ATCC Cat# CRL-2719, RRID:CVCL_5986 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_5993
Organism: Homo sapiens (Human)
Disease: Laryngeal squamous cell carcinoma
Category: Cancer cell line
Comments: Population: African American., Part of: MD Anderson Cell Lines Project., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: ATCC Cat# CRL-2723, RRID:CVCL_5993 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_0549
Organism: Spodoptera frugiperda (Fall armyworm)
Disease:
Category: Spontaneously immortalized cell line
Comments: Caution: The SfRV rhabdovirus found in Sf9 cells of ATCC CRL-1711 lot 5807852 (PubMed=24672045) does not seem to be expressed in CRL-1711 lot 5814 from 1987 (PubMed=28423032). The SfRV genome is integrated in the Sf9 genome., Anecdotal: Have been flown in space on shuttle flights STS-50 (USML-1), STS-54 and STS-57 (Spacehab-1) to study growth in microgravity (PubMed=8050503)., Karyotypic information: Heterogeneous, contains a mixture of diploid and tetraploid cells., Biotechnology: Used for the production of the Novavax SARS-CoV-2 (COVID-19) vaccine (Trade name: NVX-CoV2373) (DrugBank=DB15810). The cell line is used to produce the recombinant SARS-CoV-2 spike protein rSARS-CoV-2 which is the active part of the vaccine formulation., Group: Vaccine production cell line., Group: Space-flown cell line (cellonaut)., Group: Recombinant protein production insect cell line., Group: Insect cell line.
Proper citation: ATCC Cat# CRL-1711, RRID:CVCL_0549 Copy
https://web.expasy.org/cellosaurus/CVCL_F764
Organism: Mus musculus (Mouse)
Disease:
Category: Hybridoma
Comments:
Proper citation: ATCC Cat# CRL-2405, RRID:CVCL_F764 Copy
https://web.expasy.org/cellosaurus/CVCL_7701
Organism: Mus musculus (Mouse)
Disease:
Category: Hybridoma
Comments: Group: Patented cell line.
Proper citation: ATCC Cat# HB-10744, RRID:CVCL_7701 Copy
https://web.expasy.org/cellosaurus/CVCL_2Z99
Organism: Mus musculus (Mouse)
Disease:
Category: Finite cell line
Comments: Characteristics: Transfected with a vector containing a Shox2 promoter (PubMed=23877224).
Proper citation: ATCC Cat# CRL-3256, RRID:CVCL_2Z99 Copy
https://web.expasy.org/cellosaurus/CVCL_0032
Organism: Homo sapiens (Human)
Disease: Human papillomavirus-related cervical squamous cell carcinoma
Category: Cancer cell line
Comments: Virology: Contains a complete HPV16 genome with a disruption of the E2 region and a small deletion (PubMed=24201445)., Population: Japanese., Part of: Human Protein Atlas, Cell Atlas panel., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: ATCC Cat# HTB-35, RRID:CVCL_0032 Copy
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