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Cellosaurus is database indexing available cell lines from various collections: American Type Culture Collection (ATCC), Bioresource Collection and Research Center, Taiwan (BCRC), Banco de Células do Rio de Janeiro (BCRJ), CellBank Australia (CBA), Collection of Cell Lines in Veterinary Medicine (CCLV), Cell Lines Service (CLS), Coriell, Drosophila Genomics Resource Center (DGRC), Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSMZ), European Bank for induced pluripotent Stem Cells (EBiSC), European Collection of Authenticated Cell Cultures (ECACC), Interlab Cell Line Collection (ICLC), Institute for Fermentation Osaka (IFO), Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna (IZSLER) biobank, Japanese Collection of Research Bioresources (JCRB) Cell Bank, Kunming Cell Bank of Type Culture Collection (KCB), Korean Cell Line Bank (KCLB), Millipore, National Cell Bank of Iran (NCBI_Iran), National Cancer Institute - Developmental Therapeutics Program (NCI-DTP), NINDS Human Cell and Data Repository (NHCDR), NIH AIDS Reagent Program (NIH-ARP), NISES, RIKEN Bioresource Center Cell Bank (RCB), Royan Stem Cell Bank (RSCB), Tick Cell Biobank (TCB), Tohoku University cell line catalog (TKG), and Ximbio.
https://web.expasy.org/cellosaurus/CVCL_Z253
Organism: Estigmene acrea (Salt marsh moth)
Disease:
Category: Spontaneously immortalized cell line
Comments: Group: Recombinant protein production insect cell line., Group: Insect cell line.
Proper citation: DSMZ Cat# ACC-176, RRID:CVCL_Z253 Copy
Discontinued Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_0346
Organism: Homo sapiens (Human)
Disease: Neuroblastoma
Category: Cancer cell line
Comments: Characteristics: Neuroblastic type (N-type)., Population: Caucasian., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: DSMZ Cat# ACC-165, RRID:CVCL_0346 Copy
https://web.expasy.org/cellosaurus/CVCL_L280
Organism: Homo sapiens (Human)
Disease: Testicular teratoma
Category: Cancer cell line
Comments: Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: DSMZ Cat# ACC-747, RRID:CVCL_L280 Copy
https://web.expasy.org/cellosaurus/CVCL_2211
Organism: Homo sapiens (Human)
Disease:
Category: Hybrid cell line
Comments:
Proper citation: DSMZ Cat# ACC-598, RRID:CVCL_2211 Copy
https://web.expasy.org/cellosaurus/CVCL_2212
Organism: Rattus norvegicus (Rat)
Disease: Rat digestive system neoplasms
Category: Cancer cell line
Comments:
Proper citation: DSMZ Cat# ACC-624, RRID:CVCL_2212 Copy
Contaminated
https://web.expasy.org/cellosaurus/CVCL_1680
Organism: Homo sapiens (Human)
Disease: Human papillomavirus-related endocervical adenocarcinoma
Category: Cancer cell line
Comments: Population: African American., Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=10508494; PubMed=20143388). Originally thought to originate from an urinary bladder carcinoma..
Proper citation: DSMZ Cat# ACC-229, RRID:CVCL_1680 Copy
https://web.expasy.org/cellosaurus/CVCL_2199
Organism: Mus musculus (Mouse)
Disease: Mouse multiple myeloma
Category: Cancer cell line
Comments: Group: Hybridoma fusion partner cell line.
Proper citation: DSMZ Cat# ACC-146, RRID:CVCL_2199 Copy
Misidentified/Contaminated
https://web.expasy.org/cellosaurus/CVCL_Z327
Organism: Spodoptera frugiperda (Fall armyworm)
Disease:
Category: Spontaneously immortalized cell line
Comments: Problematic cell line: Misidentified/contaminated. Originally thought to be from a Bombyx mori chrysalid but found to be from Spodoptera frugiperda (DSMZ=ACC-186).., Group: Insect cell line.
Proper citation: DSMZ Cat# ACC-186, RRID:CVCL_Z327 Copy
https://web.expasy.org/cellosaurus/CVCL_2202
Organism: Mus musculus (Mouse)
Disease:
Category: Stromal cell line
Comments:
Proper citation: DSMZ Cat# ACC-323, RRID:CVCL_2202 Copy
https://web.expasy.org/cellosaurus/CVCL_2188
Organism: Mus musculus (Mouse)
Disease: Mouse osteosarcoma
Category: Cancer cell line
Comments: Karyotypic information: Near diploid karyotype. Has lost chromosome Y (PubMed=39662063).
Proper citation: DSMZ Cat# ACC-523, RRID:CVCL_2188 Copy
https://web.expasy.org/cellosaurus/CVCL_2074
Organism: Spodoptera frugiperda (Fall armyworm)
Disease:
Category: Spontaneously immortalized cell line
Comments: Group: Recombinant protein production insect cell line., Group: Insect cell line.
Proper citation: DSMZ Cat# ACC-292, RRID:CVCL_2074 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_0549
Organism: Spodoptera frugiperda (Fall armyworm)
Disease:
Category: Spontaneously immortalized cell line
Comments: Caution: The SfRV rhabdovirus found in Sf9 cells of ATCC CRL-1711 lot 5807852 (PubMed=24672045) does not seem to be expressed in CRL-1711 lot 5814 from 1987 (PubMed=28423032). The SfRV genome is integrated in the Sf9 genome., Anecdotal: Have been flown in space on shuttle flights STS-50 (USML-1), STS-54 and STS-57 (Spacehab-1) to study growth in microgravity (PubMed=8050503)., Karyotypic information: Heterogeneous, contains a mixture of diploid and tetraploid cells., Biotechnology: Used for the production of the Novavax SARS-CoV-2 (COVID-19) vaccine (Trade name: NVX-CoV2373) (DrugBank=DB15810). The cell line is used to produce the recombinant SARS-CoV-2 spike protein rSARS-CoV-2 which is the active part of the vaccine formulation., Group: Vaccine production cell line., Group: Space-flown cell line (cellonaut)., Group: Recombinant protein production insect cell line., Group: Insect cell line.
Proper citation: DSMZ Cat# ACC-125, RRID:CVCL_0549 Copy
https://web.expasy.org/cellosaurus/CVCL_1890
Organism: Homo sapiens (Human)
Disease: B-cell non-Hodgkin lymphoma
Category: Cancer cell line
Comments: Population: Caucasian., Part of: MD Anderson Cell Lines Project., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: DSMZ Cat# ACC-577, RRID:CVCL_1890 Copy
https://web.expasy.org/cellosaurus/CVCL_2208
Organism: Homo sapiens (Human)
Disease: Hodgkin lymphoma
Category: Cancer cell line
Comments: Population: Caucasian., Part of: LL-100 blood cancer cell line panel., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: DSMZ Cat# ACC-574, RRID:CVCL_2208 Copy
https://web.expasy.org/cellosaurus/CVCL_2204
Organism: Sus scrofa (Pig)
Disease:
Category: Spontaneously immortalized cell line
Comments: Virology: Useful for the propagation, assay and isolation of porcine parvovirus (PPV), transmissible gastroenteritis virus (TGEV) and swine enteroviruses (ATCC=CRL-1746).
Proper citation: DSMZ Cat# ACC-641, RRID:CVCL_2204 Copy
https://web.expasy.org/cellosaurus/CVCL_1920
Organism: Oncorhynchus mykiss (Rainbow trout)
Disease:
Category: Spontaneously immortalized cell line
Comments: Anecdotal: First fish cell line, established in 1962., Group: Fish cell line.
Proper citation: DSMZ Cat# ACC-352, RRID:CVCL_1920 Copy
https://web.expasy.org/cellosaurus/CVCL_Z382
Organism: Lymantria dispar (Gypsy moth)
Disease:
Category: Spontaneously immortalized cell line
Comments: Virology: Not susceptible to infection by SARS coronavirus 2 (SARS-CoV-2) (COVID-19) (PubMed=33389257)., Group: Insect cell line.
Proper citation: DSMZ Cat# ACC-181, RRID:CVCL_Z382 Copy
https://web.expasy.org/cellosaurus/CVCL_0360
Organism: Homo sapiens (Human)
Disease: Gestational choriocarcinoma
Category: Cancer cell line
Comments: Caution: Established from the trophoblastic tumor of the placenta of a 24 year old woman, but the cell line is from the male fetus., Karyotypic information: Near triploid karyotype (PubMed=33096371)., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: DSMZ Cat# ACC-462, RRID:CVCL_0360 Copy
https://web.expasy.org/cellosaurus/CVCL_0363
Organism: Homo sapiens (Human)
Disease: Gestational choriocarcinoma
Category: Cancer cell line
Comments: Caution: A TP53 mutation is indicated as being at p.Gln167His (c.501G>T) in PubMed=7819056 but has not been confirmed by CCLE and Cosmic-CLP., Karyotypic information: Near tetraploid karyotype (PubMed=33096371)., Characteristics: Established by serial cloning into hamster cheek pouches., Population: Caucasian., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: DSMZ Cat# ACC-463, RRID:CVCL_0363 Copy
https://web.expasy.org/cellosaurus/CVCL_2155
Organism: Mus musculus (Mouse)
Disease: Mouse multiple myeloma
Category: Cancer cell line
Comments: Caution: There seem to be two distinct cell lines which were assigned NCBI_Iran catalog number C522., Part of: Tumor Immunology Bank (TIB) collection from Salk (transferred to ATCC in 1981)., Group: Hybridoma fusion partner cell line.
Proper citation: DSMZ Cat# ACC-145, RRID:CVCL_2155 Copy
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