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URL: https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=126925994
Proper Citation: RRID:RGD_126925994
Description: Rattus norvegicus with name SD-Cftrem2Ang from RGD.
Species: Rattus norvegicus
Notes: The CRISPR/Cas9 system targeting at exon 3 to create gene knock out was injected to the male pronucleus of the fertalized one-cell stage embryos collected from Crl:SD. The donor DNA generated a frameshift and the creation of one XbaI restriction site and a premature stop codon. Two knockout founders ( referred as MUKORAT8.3 and MUKORAT 6.4) exhibit no difference in phenotypes and were pooled for study.
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Source: Integrated Animals
Source Database: Rat Genome Database (RGD)