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Proper Citation: RRID:MGI:5563539
Description: Allele Detail: Targeted This is a legacy resource.
Species: Mus musculus
Notes: Allele Detail: Targeted This is a legacy resource.
Phenotype: impaired macrophage phagocytosis, increased circulating interleukin-1 beta level, increased interleukin-1 beta secretion, increased interleukin-18 secretion, increased circulating interleukin-18 level, decreased macrophage cell number, abnormal macrophage physiology, increased sensitivity to induced cell death, increased macrophage apoptosis, increased susceptibility to endotoxin shock, increased susceptibility to bacterial infection, hematopoietic system phenotype
Affected Gene: Hmgb1, Lyz2
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No rating or validation information has been found for Hmgb1tm1.1Ttg/Hmgb1tm1.1Ttg; Lyz2tm1(cre)Ifo/Lyz2+.
No alerts have been found for Hmgb1tm1.1Ttg/Hmgb1tm1.1Ttg; Lyz2tm1(cre)Ifo/Lyz2+.
Source: Integrated Animals
Source Database: MGI, Mouse Genome Informatics MGI
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