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University of Texas Southwestern Medical Center Mouse Genome Engineering Core Facility (RRID:SCR_017921)Copy Citation Copied
URL: https://cri.utsw.edu/facilities/mouse-genome-engineering-core/
Proper Citation: University of Texas Southwestern Medical Center Mouse Genome Engineering Core Facility (RRID:SCR_017921)
Description: Core provides production of mouse models to support fundamental and translational research. Provides transgenic, gene targeting,DNA microinjection services, CRISPR/Cas9 microinjection, ES cell manipulation and other microinjection services to generate transgenic mice, knock-in/knock-out mice and chimeric mice harboring select genetic mutations. Other services include mouse sperm cryopreservation and recovery, in vitro fertilization (IVF), rederivation of pathogen free mouse lines and derivation of mouse embryonic stem cell lines. Provides general consultations on experimental designs and vectors for gene modification-related projects, DNA preparation, recombinant ES clones, mouse genotyping, colony breeding and husbandry, customize services as requested to support development of animal models for modeling human diseases.
Synonyms: CRI Mouse Genome Engineering Core
Resource Type: access service resource, core facility, service resource
Keywords: Production, mouse, model, translational, transgenic, gene, targeting, DNA, microinjection, CRISP, Cas9, ES, cell, manipulation, knock in, knock out, chimeric, mutation, sperm, cryopreservation, recovery, in vitro, fertilization, rederivation, pathogen, free, line, service, core, ABRF
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