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URL: http://www.grissom.gr/stranger/
Proper Citation: StRAnGER (RRID:SCR_004247)
Description: StRAnGER (Statistical Ranking of ANotated Genomic Experimental Results) is a web application for the automated statistical analysis of annotated gene profiling experiments, exploiting controlled biological vocabularies, like the Gene Ontology or the KEGG pathways terms. Starting from annotated lists of differentially expressed genes StRAnGER repartitions and reorders the initial distribution of terms to define a new distribution of elements where each element pools terms holding the same enrichment score. The elements are then prioritized according to StRAnGER''''s algorithm and, by applying bootstrapping techniques, a corrected measure of the statistical significance of these elements is derived, enabling the selection of terms mapped to these elements, unambiguously associated with respective significant gene sets. Besides their high statistical score, another selection criterion for the terms is the number of their members, something that incurs a biological prioritization in line with a Systems Biology context. Platform: Online tool
Abbreviations: StRAnGER
Synonyms: Statistical Ranking of ANotated Genomic Experimental Results
Resource Type: data analysis software, data processing software, software application, software resource
Defining Citation: PMID:21293737
Keywords: controlled vocabulary, functional analysis, genomics, annotation, visualization, statistical analysis, term enrichment, ontology or annotation visualization
Availability: Free for academic use
Resource Name: StRAnGER
Resource ID: SCR_004247
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Source: SciCrunch Registry (RRID:SCR_005400)
Description: Interactive portal for finding and submitting biomedical resources. Resources within SciCrunch have assigned RRIDs which are used to cite resources in scientific manuscripts. SciCrunch Registry, formerly NIF Registry, provides resources catalog. Allows to add new resources. Allows edit existing resources after registration. Curators are tasked with identifying and registering resources, examining data, writing configuration files to index and display data and keeping contents current.
URL: https://rrid.site/rin/sources/SCR_005400