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IKKβ inhibition prevents fat-induced beta cell dysfunction in vitro and in vivo in rodents.

Diabetologia | 2017

We have previously shown that oxidative stress plays a causal role in beta cell dysfunction induced by fat. Here, we address whether the proinflammatory kinase inhibitor of (nuclear factor) κB kinase β (IKKβ), which is activated by oxidative stress, is also implicated.

Pubmed ID: 28725915 RIS Download

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