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Exposure to dietary lipid leads to rapid production of cytosolic lipid droplets near the brush border membrane.

Nutrition & metabolism | 2016

Intestinal absorption of dietary lipids involves their hydrolysis in the lumen of proximal intestine as well as uptake, intracellular transport and re-assembly of hydrolyzed lipids in enterocytes, leading to the formation and secretion of the lipoproteins chylomicrons and HDL. In this study, we examined the potential involvement of cytosolic lipid droplets (CLD) whose function in the process of lipid absorption is poorly understood.

Pubmed ID: 27478484 RIS Download

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Associated grants

  • Agency: NIDDK NIH HHS, United States
    Id: R01 DK088210
  • Agency: NIDDK NIH HHS, United States
    Id: T32 DK007665

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Caco-2 (tool)

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Cell line Caco-2 is a Cancer cell line with a species of origin Homo sapiens (Human)

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