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WormBase 2016: expanding to enable helminth genomic research.

Nucleic acids research | 2016

WormBase (www.wormbase.org) is a central repository for research data on the biology, genetics and genomics of Caenorhabditis elegans and other nematodes. The project has evolved from its original remit to collect and integrate all data for a single species, and now extends to numerous nematodes, ranging from evolutionary comparators of C. elegans to parasitic species that threaten plant, animal and human health. Research activity using C. elegans as a model system is as vibrant as ever, and we have created new tools for community curation in response to the ever-increasing volume and complexity of data. To better allow users to navigate their way through these data, we have made a number of improvements to our main website, including new tools for browsing genomic features and ontology annotations. Finally, we have developed a new portal for parasitic worm genomes. WormBase ParaSite (parasite.wormbase.org) contains all publicly available nematode and platyhelminth annotated genome sequences, and is designed specifically to support helminth genomic research.

Pubmed ID: 26578572 RIS Download

Research resources used in this publication

None found

Antibodies used in this publication

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Associated grants

  • Agency: NHGRI NIH HHS, United States
    Id: U24 HG002223
  • Agency: Howard Hughes Medical Institute, United States
  • Agency: NHGRI NIH HHS, United States
    Id: U41-HG002223
  • Agency: Biotechnology and Biological Sciences Research Council, United Kingdom
    Id: BB/K020080
  • Agency: Medical Research Council, United Kingdom
    Id: MR/L001020/1
  • Agency: NHGRI NIH HHS, United States
    Id: U41 HG002223
  • Agency: Medical Research Council, United Kingdom
    Id: MR/L001220

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This is a list of tools and resources that we have found mentioned in this publication.


WormBook The Online Review of C. Elegans Biology (tool)

RRID:SCR_006692

WormBook is a comprehensive, open-access collection of original, peer-reviewed chapters covering topics related to the biology of Caenorhabditis elegans and other nematodes. Wormbook also contains WormMethods, a collection of protocols for nematode researchers, and the Worm Breeder''s Gazette, an informal, non-refereed, biannual newsletter for the interchange of ideas and information related to C. elegans and other nematodes. WormBook is the online text companion to WormBase, the C. elegans model organism database. WormBook contains original reviews on all aspects of C. elegans biology and up-to-date descriptions of technical procedures used to study this animal. WormBook Sections: *Genetics and genomics *Molecular biology *Biochemistry *Cell biology *Developmental control *Post-embryonic development *Sex determination *The germ line *Signal transduction *Neurobiology and behavior *Evolution and ecology *Disease models and drug discovery

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WormBase (tool)

RRID:SCR_003098

Central data repository for nematode biology including complete genomic sequence, gene predictions and orthology assignments from range of related nematodes.Data concerning genetics, genomics and biology of C. elegans and related nematodes. Derived from initial ACeDB database of C. elegans genetic and sequence information, WormBase includes genomic, anatomical and functional information of C. elegans, other Caenorhabditis species and other nematodes. Maintains public FTP site where researchers can find many commonly requested files and datasets, WormBase software and prepackaged databases.

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