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Constitutively nuclear FOXO3a localization predicts poor survival and promotes Akt phosphorylation in breast cancer.

PloS one | 2010

The PI3K-Akt signal pathway plays a key role in tumorigenesis and the development of drug-resistance. Cytotoxic chemotherapy resistance is linked to limited therapeutic options and poor prognosis.

Pubmed ID: 20808831 RIS Download

Research resources used in this publication

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Antibodies used in this publication

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Associated grants

  • Agency: Cancer Research UK, United Kingdom
    Id: 12011
  • Agency: Breast Cancer Now, United Kingdom
    Id: 2007NOVPHD16
  • Agency: Cancer Research UK, United Kingdom
    Id: C37/A5606

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Cancer Research UK (tool)

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