Indiana University School of Medicine Center for Diabetes and Metabolic Diseases Islet and Physiology Core Facility (RRID:SCR_015081)Copy Citation Copied
URL: https://medicine.iu.edu/research-centers/diabetes/cores/islet-physiology
Proper Citation: Indiana University School of Medicine Center for Diabetes and Metabolic Diseases Islet and Physiology Core Facility (RRID:SCR_015081)
Description: Services include islet isolation services from mice and rats and access to porcine and human islets. The core is equipped with BioRep Perifusion Apparatus for measurement of insulin secretion and offers services for islet and beta cell calcium imaging. Provides services for islet transplantation and assists investigators who wish to perform immunohistochemistry, immunofluorescence and/or analysis of endocrine or beta cell mass on whole pancreata from mouse and rat models.Offers services for rodent metabolic characterization, including performance of insulin and glucose tolerance testing, analysis of body composition, and metabolic cage analysis using the TSE System cages. Recently added services include zebrafish characterization to screen genes and small molecules for their effects on islet development and function.
Synonyms: , Islet and Physiology Core, Indiana Diabetes Research Center Islet and Physiology Core, Indiana Diabetes Research Center Islet and Physiology Core Facility, Indiana University School of Medicine Center for Diabetes and Metabolic Diseases Islet and Physiology Core
Resource Type: core facility, service resource, access service resource
Keywords: islets, physiology, diabetes research, islet transplantation services, beta cell mass analysis, whole pancreata, mouse, rat
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