URL: http://www.blueprintnhpatlas.org/
Proper Citation: NIH Blueprint NHP Atlas (RRID:SCR_010559)
Description: Atlas of gene expression in the developing rhesus macaque brain. This atlas is a free online resource with a unique set of data and tools aimed to create a developmental neuroanatomical framework for exploring the cellular and molecular architecture of the developing postnatal primate brain with direct relevance for human brain development. The atlas includes: * Microarray ** Microdissection: Fine structure transcriptional profiling across postnatal development for fine nuclear subdivisions of the prefrontal cortex, primary visual cortex, hippocampus, amygdala and ventral striatum ** Macrodissection: Gross structure transcriptional profiling across postnatal development for the same structures * ISH: ** Cellular resolution in situ hybridization image data of five major brain regions during postnatal developmental periods for genes clinically important for a variety of human neurodevelopmental disorders, including prefrontal cortex, primary visual cortex, hippocampus, amygdala and ventral striatum. ** Serial analysis of selected genes across the entire adult brain, focusing on cellular marker genes, genes with cortical area specificity and gene families important to neural function. * ISH Anatomic Search: Detailed gene expression search on the ISH data based on expert annotation * Reference Data: Developmental stage-specific reference series, consisting of magnetic resonance imaging (MRI) and Nissl histology to provide a neuroanatomical context for the gene expression data. These data and tools are designed to provide a valuable public resource for researchers and educators to explore neurodevelopment in non-human primates, and a key evolutionary link between other Web-based gene expression atlases for adult and developing mouse and human brain.
Abbreviations: NHP Atlas
Synonyms: NIH Blueprint Non-Human Primate Atlas
Resource Type: reference atlas, atlas, expression atlas, database, data or information resource
Keywords: molecular neuroanatomy resource, developing brain, development, brain, gene expression, postnatal, mrna transcript, in situ hybridization, prefrontal cortex, primary visual cortex, hippocampus, amygdala, ventral striatum, dna microarray, magnetic resonance imaging, nissl, histology, brain development, developmental stage, microdissection, macrodissection, microarray, cell density, neuroanatomy, non-human primate
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Allen Human Brain Atlas: BrainSpan (Atlas of the Developing Brain) |
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