URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=16137
Proper Citation: RRID:MMRRC_016137-UCD
Description: Mus musculus with name C57BL/6J-Unc13dJinx/Mmucd from MMRRC.
Species: Mus musculus
Notes: Research areas: Cell Biology, Immunology and Inflammation, Models for Human Disease, Virology; Mutation Type: chemically induced mutation ; Collection: Beutler Mutagenetix
Phenotype: increased neutrophil cell number [MP:0000219]| increased monocyte cell number [MP:0000220]| enlarged spleen [MP:0000691]| anemia [MP:0001577]| abnormal bone marrow morphology [MP:0002397]| increased susceptibility to viral infection [MP:0002418]| abnormal macrophage physiology [MP:0002451]| abnormal cytokine secretion [MP:0003009]| thrombocytopenia [MP:0003179]| decreased cytotoxic T cell cytolysis [MP:0005079]| increased CD8-positive [MP:0008078]| alpha-beta T cell number [MP:0008523]| absent lymph node germinal center [MP:0010766]
Affected Gene: Unc13d
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Source: Integrated Animals
Source Database: Mutant Mouse Resource and Research Center (MMRRC)