URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=15958
Proper Citation: RRID:MMRRC_015958-UCD
Description: Mus musculus with name B6.129S4-Zmpste24tm1Sgy/Mmucd from MMRRC.
Species: Mus musculus
Notes: Research areas: ; Mutation Type: Targeted Mutation ; Collection:
Phenotype: fragile skeleton [MP:0000061]| decreased bone mineral density [MP:0000063]| abnormal trabecular bone morphology [MP:0000130]| decreased compact bone thickness [MP:0000135]| abnormal rib morphology [MP:0000150]| kyphosis [MP:0000160]| alopecia [MP:0000414]| abnormal mandible morphology [MP:0000458]| abnormal esophageal squamous epithelium morphology [MP:0000469]| abnormal colon morphology [MP:0000495]| abnormal tibia morphology [MP:0000558]| weakness [MP:0000746]| muscle weakness [MP:0000747]| progressive muscle weakness [MP:0000748]| decreased body weight [MP:0001262]| weight loss [MP:0001263]| abnormal gait [MP:0001406]| aphagia [MP:0001438]| abnormal grip strength [MP:0001515]| abnormal skeleton physiology [MP:0001533]| extended life span [MP:0001661]| postnatal growth retardation [MP:0001732]| premature death [MP:0002083]| abnormal axial skeleton morphology [MP:0002114]| abnormal craniofacial bone morphology [MP:0002116]| abnormal fibula morphology [MP:0002187]| micrognathia [MP:0002639]| abnormal cranial suture morphology [MP:0002835]| abnormal thoracic vertebrae morphology [MP:0003047]| abnormal lumbar vertebrae morphology [MP:0003049]| abnormal cell nucleus morphology [MP:0003111]| abnormal long bone morphology [MP:0003723]| abnormal bone structure [MP:0003795]| abnormal zygomatic arch morphology [MP:0004469]| dilated esophagus [MP:0004548]| rib fractures [MP:0004675]| cachexia [MP:0005150]| abnormal zygomatic bone morphology [MP:0005270]| abnormal incisor morphology [MP:0005358]| increased susceptibility to weight gain [MP:0005455]| abnormal skeleton morphology [MP:0005508]| decreased circulating glucose level [MP:0005560]| decreased circulating total protein level [MP:0005567]| abnormal cell physiology [MP:0005621]| decreased survivor rate [MP:0008770]| decreased subcutaneous adipose tissue amount [MP:0008844]| distended cecum [MP:0009480]| decreased susceptibility to bone fracture [MP:0009878]| decreased grip strength [MP:0010053]| postnatal lethality [MP:0011085]| complete penetrance [MP:0011570]| esophageal achalasia [MP:0030082]| long lower incisors [MP:0030136]
Affected Gene: Zmpste24
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Source: Integrated Animals
Source Database: Mutant Mouse Resource and Research Center (MMRRC)