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Drug Related Gene Database: DRG

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Renthal et al., Neuron 2009PDE8B Phosphodiesterase 8BNucleus accumbensCocaine (Delta FosB and dimethyl-K9 / K27 histone H3) (Experiment)C57BL/6 Mouse: Male, 10-12 weeks Adult mouseIncreased binding and increased expressionchromatin immunoprecipitation before dna microarrayChronic cocainetable:S8, Cocaine Regulation of Histone Modifications at Delta FosB Target Genes., Delta fosB and meH3 up