Searching across hundreds of databases
The enteric nervous system is thought to originate solely from the neural crest. Transgenic lineage tracing revealed a novel population of clonal pancreatic duodenal homeobox-1 (Pdx1)-Cre lineage progenitor cells in the tunica muscularis of the gut that produced pancreatic descendants as well as neurons upon differentiation in vitro. Additionally, an in vivo subpopulation of endoderm lineage enteric neurons, but not glial cells, was seen especially in the proximal gut. Analysis of early transgenic embryos revealed Pdx1-Cre progeny (as well as Sox-17-Cre and Foxa2-Cre progeny) migrating from the developing pancreas and duodenum at E11.5 and contributing to the enteric nervous system. These results show that the mammalian enteric nervous system arises from both the neural crest and the endoderm. Moreover, in adult mice there are separate Wnt1-Cre neural crest stem cells and Pdx1-Cre pancreatic progenitors within the muscle layer of the gut.
Pubmed ID: 30472119 RIS Download
Publication data is provided by the National Library of Medicine ® and PubMed ®. Data is retrieved from PubMed ® on a weekly schedule. For terms and conditions see the National Library of Medicine Terms and Conditions.
Digital image processing system where microscope settings and processing steps may be adjusted in single user interface. Can acquire images from variety of cameras. Includes software package for capturing, archiving and preparing images for publication. Allows users to visualize and present images in several dimensions. Functionality of imaging toolbox expands constantly with wide range of different modules that are tailored to specific applications or microscope accessories. This resource is duplicated by SCR_018376
View all literature mentionsCommercial antibody vendor which supplies antibodies and other products to life science researchers.
View all literature mentionsAn antibody supplier which banks and distributes hybridomas and monoclonal antibodies for use in research. The bank includes antibodies against targets such as GFP, transcription factors, stem cells, and human.
View all literature mentionsThis polyclonal targets Pancreatic Amylase
View all literature mentionsThis polyclonal targets Peripherin
View all literature mentionsThis monoclonal targets Nestin
View all literature mentionsThis monoclonal targets Serotonin
View all literature mentionsThis monoclonal targets Neurofilament 200 kD
View all literature mentionsThis monoclonal targets S-100 (beta-Subunit)
View all literature mentionsThis polyclonal secondary targets IgG (H+L)
View all literature mentionsThis monoclonal targets p75 NGF Receptor
View all literature mentionsThis polyclonal targets Rabbit IgG (H+L)
View all literature mentionsThis monoclonal targets GFAP
View all literature mentionsThis polyclonal targets Vip
View all literature mentionsThis polyclonal targets Mouse IgG (H+L)
View all literature mentionsThis polyclonal secondary targets IgG (H+L)
View all literature mentionsThis polyclonal targets Tyrosine Hydroxylase
View all literature mentionsThis monoclonal targets β-Tubulin III
View all literature mentionsThis unknown targets Calretinin
View all literature mentionsThis polyclonal targets GFP
View all literature mentionsThis monoclonal targets Green Fluorescent Protein
View all literature mentionsThis polyclonal targets Neuropeptide Y (NPY) antibody produced in rabbit
View all literature mentionsThis polyclonal targets C Peptide
View all literature mentionsThis polyclonal secondary targets IgG (H+L)
View all literature mentionsThis monoclonal targets Actin, alpha, Smooth Muscle
View all literature mentionsThis polyclonal secondary targets IgG (H+L)
View all literature mentionsThis recombinant monoclonal targets Pdx1
View all literature mentionsThis monoclonal targets MAP-2 (Microtubule Associated Protein, MAP-2A and -2B)
View all literature mentionsThis monoclonal targets pancreatic duodenal homeobox protein 1 (Pdx1)
View all literature mentionsMus musculus with name B6.129X1-Gt(ROSA)26Sortm1(EYFP)Cos/J from IMSR.
View all literature mentionsMus musculus with name B6.Cg-Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/J from IMSR.
View all literature mentionsMus musculus with name B6.FVB-Tg(Pdx1-cre)6Tuv/J from IMSR.
View all literature mentionsMus musculus with name Crl:CD1(ICR) from IMSR.
View all literature mentionsMus musculus with name STOCK Foxa2tm1.1(rtTa)Moon/J from IMSR.
View all literature mentionsThis polyclonal targets Tyrosine Hydroxylase
View all literature mentionsThis polyclonal targets Peripherin
View all literature mentionsThis polyclonal secondary targets IgG (H+L)
View all literature mentionsThis polyclonal targets Rabbit IgG (H+L)
View all literature mentionsThis monoclonal targets Actin, alpha, Smooth Muscle
View all literature mentionsThis monoclonal targets S-100 (beta-Subunit)
View all literature mentionsThis monoclonal targets Neurofilament 200 kD
View all literature mentionsThis polyclonal secondary targets IgG (H+L)
View all literature mentionsThis polyclonal secondary targets IgG (H+L)
View all literature mentionsThis polyclonal secondary targets IgG (H+L)
View all literature mentionsThis polyclonal targets Mouse IgG (H+L)
View all literature mentionsThis monoclonal targets MAP-2 (Microtubule Associated Protein, MAP-2A and -2B)
View all literature mentionsThis monoclonal targets Serotonin
View all literature mentionsThis polyclonal targets Neuropeptide Y (NPY) antibody produced in rabbit
View all literature mentionsThis polyclonal targets Vip
View all literature mentionsThis monoclonal targets GFAP
View all literature mentionsThis monoclonal targets pancreatic duodenal homeobox protein 1 (Pdx1)
View all literature mentionsThis recombinant monoclonal targets Pdx1
View all literature mentionsThis polyclonal targets Peripherin
View all literature mentionsMus musculus with name B6.129X1-Gt(ROSA)26Sortm1(EYFP)Cos/J from IMSR.
View all literature mentionsMus musculus with name B6.FVB-Tg(Pdx1-cre)6Tuv/J from IMSR.
View all literature mentionsThis monoclonal targets p75 NGF Receptor
View all literature mentionsThis polyclonal targets Tyrosine Hydroxylase
View all literature mentionsThis unknown targets Calretinin
View all literature mentionsThis monoclonal targets Nestin
View all literature mentionsThis polyclonal targets GFP
View all literature mentionsThis monoclonal targets Green Fluorescent Protein
View all literature mentionsMus musculus with name B6.Cg-Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/J from IMSR.
View all literature mentionsThis monoclonal targets β-Tubulin III
View all literature mentionsThis polyclonal targets C Peptide
View all literature mentionsThis polyclonal targets Pancreatic Amylase
View all literature mentionsThe SciCrunch Infrastructure was developed as a cooperative data platform to be used by diverse communities in making data more FAIR.
scicrunch.org
