Activation of PKC-ζ is closely linked to the pathogenesis of cardiac hypertrophy. PKC-ζ can be activated by certain lipid metabolites such as phosphatidylinositol (3,4,5)-trisphosphate and ceramide. However, its endogenous negative regulators are not well defined. Here, the role of the sirtuin1-PKC-ζ signalling axis and the underlying molecular mechanisms were investigated in cardiac hypertrophy.
Pubmed ID: 30414383 RIS Download
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View all literature mentionsSoftware used for Bio-Rad imaging systems to acquire, quantitate, and analyze a variety of data. The software allows automatic configuration of imaging systems with appropriate filters, lasers, LEDs, and other illumination sources. It also contains tools for automated analysis of tests and assays such as 1-D electrophoretic gels, western blots, and colony counts.
View all literature mentionsThis unknown targets mouse IgG (H+L) F(ab')2 Fragment (Alexa Fluor 555 Conjugate)
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View all literature mentionsImaging software for high-frequency processing and analysis. Some of its features include modes for blood flow quantification, single line acquisition, 3D-Mode imaging & volume analysis, nonlinear contrast imaging, and other image processing functions.
View all literature mentions