Non-canonical Activation of the DNA Sensing Adaptor STING by ATM and IFI16 Mediates NF-κB Signaling after Nuclear DNA Damage.

Addgene (tool)

RRID:SCR_002037

Non-profit plasmid repository dedicated to helping scientists around the world share high-quality plasmids. Facilitates archiving and distributing DNA-based research reagents and associated data to scientists worldwide. Repository contains over 65,000 plasmids, including special collections on CRISPR, fluorescent proteins, and ready-to-use viral preparations. There is no cost for scientists to deposit plasmids, which saves time and money associated with shipping plasmids themselves. All plasmids are fully sequenced for validation and sequencing data is openly available. We handle the appropriate Material Transfer Agreements (MTA) with institutions, facilitating open exchange and offering intellectual property and liability protection for depositing scientists. Furthermore, we curate free educational resources for the scientific community including a blog, eBooks, video protocols, and detailed molecular biology resources.

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Mendeley Data (tool)

RRID:SCR_002750

A free reference manager and academic social network to organize your research, collaborate with others online, and discover the latest research. Automatically generate bibliographies, Collaborate easily with other researchers online, Easily import papers from other research software, Find relevant papers based on what you're reading, Access your papers from anywhere online, Read papers on the go with the iPhone app. The software, Mendeley Desktop, offers: * Automatic extraction of document details * Efficient management of your papers * Sharing and synchronization of your library (or parts of it) * Additional features: A plug-in for citing your articles in Microsoft Word, OCR (image-to-text conversion, so you can full-text search all your scanned PDFs), etc The website, Mendeley Web, complements Mendeley Desktop by offering these features: * An online back up of your library * Statistics of all things interesting * A research network that allows you to keep track of your colleagues' publications, conference participations, awards etc * A recommendation engine for papers that might interest you

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HaCaT (tool)

RRID:CVCL_0038

Cell line HaCaT is a Spontaneously immortalized cell line with a species of origin Homo sapiens (Human)

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HEK293 (tool)

RRID:CVCL_0045

Cell line HEK293 is a Transformed cell line with a species of origin Homo sapiens (Human)

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MRC-5 (tool)

RRID:CVCL_0440

Cell line MRC-5 is a Finite cell line with a species of origin Homo sapiens

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THP-1 (tool)

RRID:CVCL_0006

Cell line THP-1 is a Cancer cell line with a species of origin Homo sapiens (Human)

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HEK293T (tool)

RRID:CVCL_0063

Cell line HEK293T is a Transformed cell line with a species of origin Homo sapiens (Human)

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AIF (D39D2) XP Rabbit mAb (antibody)

RRID:AB_10634755

This recombinant monoclonal targets AIF

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Goat anti-Rabbit IgG (H+L) Highly Cross-Adsorbed Secondary Antibody, Alexa Fluor™ 488 (antibody)

RRID:AB_2576217

This polyclonal secondary targets IgG (H+L)

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Goat Anti-Mouse IgG (H+L) Highly Cross-adsorbed Antibody, Alexa Fluor 488 Conjugated (antibody)

RRID:AB_2534088

This polyclonal secondary targets IgG (H+L)

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Goat Anti-Mouse IgG (H+L) Highly Cross-adsorbed Antibody, Alexa Fluor ?? 647 Conjugated (antibody)

RRID:AB_2535805

This unknown targets IgG (H+L)

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donkey anti-goat IgG-HRP (antibody)

RRID:AB_631728

This polyclonal targets donkey anti-goat IgG-HRP

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Anti-rabbit IgG, HRP-linked Antibody (antibody)

RRID:AB_2099233

This polyclonal secondary targets IgG

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Anti-mouse IgG, HRP-linked Antibody (antibody)

RRID:AB_330924

This polyclonal targets IgG

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Monoclonal Anti-β-Actin antibody produced in mouse (antibody)

RRID:AB_476697

This monoclonal targets β-Actin

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Mouse Anti-GAPDH Monoclonal Antibody, Unconjugated (antibody)

RRID:AB_2107299

This monoclonal targets Gapdh

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Histone H3 (D1H2) XP Rabbit mAb (antibody)

RRID:AB_10544537

This monoclonal targets Histone H3 (D1H2) XP Rabbit mAb

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Anti-MB21D1 antibody produced in rabbit (antibody)

RRID:AB_10601693

This polyclonal targets MB21D1 antibody produced in rabbit

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Goat Anti-Human IFI-16 (C-18) Polyclonal, Unconjugated (antibody)

RRID:AB_648739

This polyclonal targets Human IFI16

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Mouse Anti-Human IFI-16 (1G7) Monoclonal, Unconjugated, Clone 1g7 (antibody)

RRID:AB_627775

This monoclonal targets Human IFI16

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K63-linkage Specific Polyubiquitin (D7A11) Rabbit mAb (antibody)

RRID:AB_10827985

This monoclonal targets K63-linkage Specific Polyubiquitin (D7A11) Rabbit mAb

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HA-Tag (6E2) Mouse mAb (antibody)

RRID:AB_10691311

This monoclonal targets HA-Tag

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TRAF6 (D21G3) Rabbit mAb (antibody)

RRID:AB_10858223

This monoclonal targets TRAF6 (D21G3) Rabbit mAb

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Phospho-IRF-3 (Ser396) (4D4G) Rabbit mAb (antibody)

RRID:AB_823547

This monoclonal targets Phospho-IRF-3 (Ser396)

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IRF-3 (D6I4C) XP® (antibody)

RRID:AB_2722521

This monoclonal targets IRF3

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Phospho-TBK1/NAK (Ser172) (D52C2) XP Rabbit monoclonal Antibody (antibody)

RRID:AB_10693472

This monoclonal targets Phospho-TBK1/NAK (Ser172)

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TBK1/NAK (D1B4) XP(tm) Rabbit mAb (antibody)

RRID:AB_2255663

This monoclonal targets Tbk1

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Phospho-NF-κB p65 (Ser536) (93H1) Rabbit mAb (antibody)

RRID:AB_331284

This monoclonal targets NF-KappaB p65, phospho (Ser536)

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NF- B p65 (L8F6) Mouse mAb (antibody)

RRID:AB_10828935

This monoclonal targets NF-κB p65

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Phospho-Histone H2A.X (Ser139) Antibody (antibody)

RRID:AB_2118010

This polyclonal targets Phospho-Histone H2A.X (Ser139)

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STING (D2P2F) (antibody)

RRID:AB_2732796

This monoclonal targets STING

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OMERO (software resource)

RRID:SCR_002629

Client-server software for management, visualization, and analysis of biological microscopy images. OMERO handles images in a secure central repository where users can view, organize, analyze and share data from anywhere with internet access. Work with images from a desktop app (Windows, Mac or Linux), from the web or from 3rd party software.

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ZEISS ZEN Microscopy Software (software resource)

RRID:SCR_013672

User interface software for Carl Zeiss light microscopy imaging systems. ZEN is the universal user interface you will see on every imaging system from ZEISS. After selecting fluorophore, ZEN applies the necessary settings to collect and organize data.

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Image Studio Lite (software resource)

RRID:SCR_013715

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 28,2023. Software application which can analyze basic Western blot data and export them for use in spreadsheet programs. Users can create standardized or custom lab reports and can share them with colleagues. Image Studio Lite has been discontinued and replaced with Empiria Studio Software.

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