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Microglia-the resident immune cells of the brain-are activated after brain lesions, e.g., cerebral ischemia, and polarize towards a classic "M1" pro-inflammatory or an alternative "M2" anti-inflammatory phenotype following characteristic temporo-spatial patterns, contributing either to secondary tissue damage or to regenerative responses. They closely interact with endogenous neural stem cells (NSCs) residing in distinct niches of the adult brain. The current study aimed at elucidating the dynamics of microglia polarization and their differential effects on NSC function.
Pubmed ID: 30103769 RIS Download
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View all literature mentionsSoftware for image processing, analysis, and editing. The software includes features such as touch capabilities, a customizable toolbar, 2D and 3D image merging, and Cloud access and options.
View all literature mentionsThis polyclonal secondary targets IgG (H+L)
View all literature mentionsThis polyclonal targets GFAP
View all literature mentionsThis monoclonal targets BrdU
View all literature mentionsThis polyclonal targets Doublecortin
View all literature mentionsOpen source Java based image processing software program designed for scientific multidimensional images. ImageJ has been transformed to ImageJ2 application to improve data engine to be sufficient to analyze modern datasets.
View all literature mentionsThis monoclonal targets Human SOX2
View all literature mentionsThis monoclonal targets Cnp
View all literature mentionsThis monoclonal targets GFAP
View all literature mentionsThis monoclonal targets beta-III Tubulin
View all literature mentionsThis monoclonal targets BrdU
View all literature mentionsThis polyclonal targets Iba1
View all literature mentionsThis unknown targets Mouse IgG2a
View all literature mentionsThis unknown targets Mouse IgG2a
View all literature mentionsThis polyclonal secondary targets IgG1
View all literature mentionsThis polyclonal secondary targets IgG1
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