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Haem oxygenase-1 up-regulation by rosiglitazone via ROS-dependent Nrf2-antioxidant response elements axis or PPARγ attenuates LPS-mediated lung inflammation.

British journal of pharmacology | 2018

Haem oxygenase-1 (HO-1) is induced by thiazolidinediones including rosiglitazone and exerts anti-inflammatory effects in various models. However, the molecular mechanisms underlying rosiglitazone-induced HO-1 expression remain largely unknown in human pulmonary alveolar epithelial cells (HPAEpiCs).

Pubmed ID: 30088830 RIS Download

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This is a list of tools and resources that we have found mentioned in this publication.


c-Src (SRC 2) (antibody)

RRID:AB_631324

This polyclonal targets SRC

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Phospho-Pyk2 (Tyr402) Antibody (antibody)

RRID:AB_2300530

This polyclonal targets Phospho-Pyk2 (Tyr402)

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Phospho-Akt (Ser473) Antibody (antibody)

RRID:AB_329825

This polyclonal targets Phospho-Akt (Ser473)

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Phospho-Src Family (Tyr416) Antibody (antibody)

RRID:AB_331697

This polyclonal targets Phospho-Src Family (Tyr416)

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PYK2 antibody [E354] (antibody)

RRID:AB_777568

This monoclonal targets PYK2

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Rabbit Anti-p47 phox (Phospho-Ser370) Polyclonal, Unconjugated (antibody)

RRID:AB_10696129

This polyclonal targets Rabbit p47 phox (Phospho-Ser370)

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Nrf2 (phospho S40) antibody [EP1809Y] (antibody)

RRID:AB_1524049

This monoclonal targets Human Nrf2 (phospho S40)

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NOX2/gp91phox antibody [EPR6991] (antibody)

RRID:AB_11144496

This monoclonal targets NOX2/gp91phox antibody [EPR6991]

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HO-1, pAb (antibody)

RRID:AB_10618757

This polyclonal targets HO-1 pAb

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Lamin A (H-102) (antibody)

RRID:AB_648148

This polyclonal targets LMNA

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Keap1 (H-190) (antibody)

RRID:AB_2280949

This polyclonal targets KEAP1

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ICAM-1 (H-108) (antibody)

RRID:AB_647486

This polyclonal targets Human ICAM1

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Akt1/2/3 (H-136) (antibody)

RRID:AB_671714

This polyclonal targets AKT1, AKT3

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β-Actin Antibody (C4) (antibody)

RRID:AB_2714189

This monoclonal targets β-Actin

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Nrf2 (C-20) (antibody)

RRID:AB_2108502

This polyclonal targets NFE2L2

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BD CellQuest Pro (software resource)

RRID:SCR_014489

A software for acquiring and analyzing flow cytometry data. The user can create plots with elements like regions, gates, statistics, markers, and annotated text. The software can also be used for batch analysis or quality control of analysis. Results can be exported and saved.

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GraphPad Prism (software resource)

RRID:SCR_002798

Statistical analysis software that combines scientific graphing, comprehensive curve fitting (nonlinear regression), understandable statistics, and data organization. Designed for biological research applications in pharmacology, physiology, and other biological fields for data analysis, hypothesis testing, and modeling.

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THP-1 (cell line)

RRID:CVCL_0006

Cell line THP-1 is a Cancer cell line with a species of origin Homo sapiens (Human)

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GraphPad Prism (software resource)

RRID:SCR_002798

Statistical analysis software that combines scientific graphing, comprehensive curve fitting (nonlinear regression), understandable statistics, and data organization. Designed for biological research applications in pharmacology, physiology, and other biological fields for data analysis, hypothesis testing, and modeling.

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BD CellQuest Pro (software resource)

RRID:SCR_014489

A software for acquiring and analyzing flow cytometry data. The user can create plots with elements like regions, gates, statistics, markers, and annotated text. The software can also be used for batch analysis or quality control of analysis. Results can be exported and saved.

View all literature mentions