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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

(last updated: Oct 12, 2019)

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Resource NameResource TypeDescriptionKeywordsResource IDProper CitationParent OrganizationRelated ConditionFunding AgencyRelationReferenceWebsite StatusAlternate IDsAlternate URLsOld URLs
Action to Control Cardiovascular Disease Risk in Diabetes Follow-up Study (ACCORDION)Resource, data set, topical portal, portal, data or information resourceA prospective, observational follow-up study of at least 8000 participants who were treated and followed in the Action to Control Cardiovascular Risk in Diabetes (ACCORD) Trial. Treatment in ACCORD ended in 2009 and ACCORDION is designed to further elucidate the long-term effects of the ACCORD treatment strategies and provide additional data on the relationships among various cardiovascular and diabetic risk factors.follow up, long term effect, treatment strategy, accord, cardiovascular risk factor, diabetic risk factorSCR_014373(Action to Control Cardiovascular Disease Risk in Diabetes Follow-up Study (ACCORDION), RRID:SCR_014373)Wake Forest School of Medicine; North Carolina; USA Type 2 diabetesNHLBIlisted by: NIDDK Information Network, NIDDK Research Resources, submitted by: NIDDK Information NetworkLast checked down
Sleep Heart Health StudyResource, disease-related portal, topical portal, portal, data or information resourcePortal for a multi-cohort study focused on sleep-disordered breathing and cardiovascular outcomes implemented by the National Heart Lung and Blood Institute. Recorded signals are: EEG, ECG, EOG, SaO2, HR, EOG, EMG, respiratory inductance plethysmography, respiration (thermistor), position, light.dataset, analysis, sleep, apnea, breathing, disorder, cardiovascular, disease, EEG, ECG, respiration, PSGSCR_016559(Sleep Heart Health Study, RRID:SCR_016559)sleep disorder, sleep apnea, cardiovascular diseaseNHLBIlisted by: National Sleep Research Resource (NSRR), submitted by: Resource Identification PortalPMID:9493915Last checked down
Apnea, Bariatric surgery, and CPAP studyResource, disease-related portal, topical portal, portal, data or information resourcePortal for randomized controlled trial to compare effectiveness of bariatric surgery versus continuous positive airway pressure (CPAP) therapy for obstructive sleep apnea. Signals included in the polysomnography (PSG) montage are EEG, EMG, EOG, ECG, SpO2, airflow, CPAP pressure, CPAP flow, plethysmography, position, pulse, light, respiratory effort, snore.dataset, bariatric, surgery, continuous, positive, airway, pressure, therapy, sleep, apnea, obesity IISCR_016575(Apnea, Bariatric surgery, and CPAP study, RRID:SCR_016575)class II obesity, obstructive sleep apneaNHLBIlisted by: National Sleep Research Resource (NSRR)DOI:10.1164/rccm.201708-1637LELast checked down
Best Apnea Interventions for Research (BestAIR) sleep studyResource, disease-related portal, topical portal, portal, data or information resourcePortal for sleep study to address challenges in conducting future large-scale trials of sleep apnea treatment. Includes data from sleep apnea patients with cardiovascular disease or risk factors. Signals included in the polysomnography (PSG) montage are ECG, SpO2, airflow, nasal pressure, position, pulse, respiratory effort, snore, tidal, analysis, sleep, apnea, treatment, cardiovascular, disease, risk, factor, polysomnography, ECG, SpO2SCR_016583(Best Apnea Interventions for Research (BestAIR) sleep study, RRID:SCR_016583)sleep apnea, cardiovascular diseaseNHLBI, Philips Respironics, ResMed Foundationlisted by: National Sleep Research Resource (NSRR)DOI:10.5665/sleep.4266Last checked down
Cleveland Family StudyResource, disease-related portal, topical portal, portal, data or information resourcePortal for family based study of sleep apnea. Contains data for quantifying the familial aggregation of sleep apnea. The polysomnographic (PSG) montage signals: EEG, ECG, EOG, EMG, SpO2, plethysmography, airflow (thermistor), nasal pressure, respiratory effort, position,, polysomnography, sleep apnea, family, familial aggregation, EEG, ECG, longitudinalSCR_016585(Cleveland Family Study, RRID:SCR_016585)sleep disorderNCRR, NHLBI, NIHlisted by: National Sleep Research Resource (NSRR), submitted by: Resource Identification PortalPMID:7881656Last checked down
Trans-Institute Angiogenesis Research Program Resource, portal, topical portal, resource, data or information resourceTrans-NIH program encouraging and facilitating the study of the underlying mechanisms controlling blood vessel growth and development. Other aims include: to identify specific targets and to develop therapeutics against pathologic angiogenesis in order to reduce the morbidity due to abnormal blood vessel proliferation in a variety of disease states; to better understand the process of angiogenesis and vascularization to improve states of decreased vascularization; to encourage and facilitate the study of the processes of lymphangiogenesis; and to achieve these goals through a multidisciplinary approach, bringing together investigators with varied backgrounds and varied interests.blood vessel, growth, development, target, therapeutic, vascularization, angiogenesis, lymphangiogenesisSCR_000384( Trans-Institute Angiogenesis Research Program , RRID:SCR_000384)National Institutes of Health Angiogenesis, LymphangiogenesisJDRF, NCI, NEI, NHLBI, NICHD, NIDDK, NINDSlisted by: NIDDK Information Network, submitted by: NIDDK Information NetworkLast checked downnlx_152866
Sleep Disorder Knowledge PortalResource, disease-related portal, topical portal, portal, data or information resourceSoftware platform for accelerating genetic discoveries for sleep disturbance and circadian traits.genetic, discovery, sleep, disorder, circadian, traitSCR_016611(Sleep Disorder Knowledge Portal, RRID:SCR_016611)Broad Institute of MIT and Harvard , Massachusetts General Hospital Sleep disorder, Circadian traitsNational Institute of Diabetes and Digestive and Kidney Diseases, NHLBILast checked up
Macaque.orgResource, disease-related portal, topical portal, research forum portal, organization portal, laboratory portal, portal, data or information resourceMacaque genomic and proteomic resources and how they are providing important new dimensions to research using macaque models of infectious disease. The research encompasses a number of viruses that pose global threats to human health, including influenza, HIV, and SARS-associated coronavirus. By combining macaque infection models with gene expression and protein abundance profiling, they are uncovering exciting new insights into the multitude of molecular and cellular events that occur in response to virus infection. A better understanding of these events may provide the basis for innovative antiviral therapies and improvements to vaccine development strategies.genomic, hiv, infection, proteomic, virus, simian immunodeficiency virus, influenza virus, animal modelSCR_002767(, RRID:SCR_002767)University of Washington; Seattle; USA Viral infection, Infectious diseaseNCRR, NHLBI, NIAID, NIDALast checked upnif-0000-24370
Patient-Reported Outcomes Measurement Information SystemResource, topical portal, assessment test provider, data set, service resource, portal, storage service resource, data repository, material resource, data or information resourceRepository of person centered measures that evaluates and monitors physical, mental, and social health in adults and, child, assessment, clinical, anger, pain, fatigue, physical function, depression, anxiety, social function, patient reported outcome, health, measureSCR_004718(Patient-Reported Outcomes Measurement Information System, RRID:SCR_004718)University of Washington; Seattle; USA NCCIH, NCI, NHLBI, NIA, NIAMS, NIDA, NIDCD, NIDDK, NIMH, NINDS, NINR, ODrecommended by: National Library of Medicine, BRAIN InitiativeLast checked upnlx_143881
Cardiovascular Proteomics CenterResource, topical portal, portal, data or information resourceThe Cardiovascular Proteomics Center is a research center funded by the NIH/NHLBI to analyze and identify proteins that may be modified or created by oxidative stress. The CPC is developing and applying new proteomics methodology and instrumentation to the analysis of known proteins and those yet to be discovered.protein, cardiovascular, proteomics, heart, oxidative stress, mass spectrometry, biology, clinicalSCR_000603(Cardiovascular Proteomics Center, RRID:SCR_000603)Boston University School of Medicine; Massachusetts; USA NHLBILast checked upnlx_149148
NSR Physiome ProjectResource, topical portal, training resource, software application, portal, professional program, software resource, simulation software, data or information resourceDatabase of physiological, pharmacological, and pathological information on humans and other organisms and integration through computational modeling. Models include everything from diagrammatic schema, suggesting relationships among elements composing a system, to fully quantitative, computational models describing the behavior of physiological systems and an organism''s response to environmental change. Each mathematical model is an internally self-consistent summary of available information, and thereby defines a working hypothesis about how a system operates. Predictions from such models are subject to test, with new results leading to new models.BR /> A Tool developed for the NSR Physiome project is JSim, an open source, free software. JSim is a Java-based simulation system for building quantitative numeric models and analyzing them with respect to experimental reference data. JSim''s primary focus is in physiology and biomedicine, however its computational engine is quite general and applicable to a wide range of scientific domains. JSim models may intermix ODEs, PDEs, implicit equations, integrals, summations, discrete events and procedural code as appropriate. JSim''s model compiler can automatically insert conversion factors for compatible physical units as well as detect and reject unit unbalanced equations. JSim also imports the SBML and CellML model archival formats. All JSim models are open source. Goals of the Physiome Project: - To develop and database observations of physiological phenomenon and interpret these in terms of mechanism (a fundamentally reductionist goal). - To integrate experimental information into quantitative descriptions of the functioning of humans and other organisms (modern integrative biology glued together via modeling). - To disseminate experimental data and integrative models for teaching and research. - To foster collaboration amongst investigators worldwide, to speed up the discovery of how biological systems work. - To determine the most effective targets (molecules or systems) for therapy, either pharmaceutic or genomic. - To provide information for the design of tissue-engineered, biocompatible implants.physiome, computational modeling, cell, organ, organism, human, model, physiological, pharmacological, pathological, model repository, sbml, cellml, biophysics, biochemistry, database, proteome, jsim simulation analysis system, data analysis tool, parameter optimization tool, integrating biological systemSCR_007379(NSR Physiome Project, RRID:SCR_007379)University of Washington; Seattle; USA NHLBI, NIBIB, NSFLast checked upnif-0000-00532
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