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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

(last updated: Oct 12, 2019)

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886 Results - per page

Resource NameResource TypeDescriptionKeywordsResource IDProper CitationParent OrganizationRelated ConditionFunding AgencyRelationReferenceWebsite StatusAlternate IDsAlternate URLsOld URLs
IMPACT Prognostic CalculatorResource, analysis service resource, data analysis service, service resource, production service resourceA calculator that calculates the prediction models for 6 month outcome after Traumatic Brain Injury. Based on extensive prognostic analysis the IMPACT investigators have developed prognostic models for predicting 6 month outcome in adult patients with moderate to severe head injury (Glasgow Coma Scale <=12) on admission. By entering the characteristics into the calculator, the models will provide an estimate of the expected outcome at 6 months. We present three models of increasing complexity (Core, Core + CT, Core + CT + Lab). These models were developed and validated in collaboration with the CRASH trial collaborators on large numbers of individual patient data (the IMPACT database). The models discriminate well, and are particularly suited for purposes of classification and characterization of large cohorts of patients. Extreme caution is required when applying the estimated prognosis to individual patients. The sequential prediction models may be used as an aid to estimate 6 month outcome in patients with severe or moderate traumatic brain injury (TBI). However, the prediction rule can only complement, never replace, clinical judgment and can therefore be used only as a decision-support system.traumatic brain injury, head injury, brain injury, adult, human, severe, moderate, glasgow coma scale, one mind tbiSCR_004730(IMPACT Prognostic Calculator, RRID:SCR_004730)IMPACT: International Mission for Prognosis and Analysis of Clinical Trials in TBI Traumatic brain injuryNINDSLast checked upnlx_143884
Mouse Mutant ResourceResource, organism supplier, material analysis service, analysis service resource, biomaterial supply resource, production service resource, service resource, cell repository, biomaterial analysis service, material resourceProducer and supplier of a collection of mice bearing spontaneous mutations. These mice contribute to a better understanding of the genetic bases of neurological, neuromuscular, sensory, metabolic, skeletal/craniofacial and developmental disorders and conditions such as diabetes, obesity and heart disease.live, cryopreserved, frozen, spontaneous mutation, dna, mutant, gene, disease model, mouse model, embryo, germplasm, mutation, phenotypeSCR_008367(Mouse Mutant Resource, RRID:SCR_008367)Jackson Laboratory Spontaneous mutationJackson Laboratory, NCRR, NIH Blueprint for Neuroscience Research, NIH Office of the Directorlisted by: One Mind Biospecimen Bank ListingLast checked upnif-0000-25583
Stanley Neuropathology Consortium Integrative DatabaseResource, data analysis service, production service resource, analysis service resource, database, data set, service resource, data or information resourceA database of 1749 neuropathological markers measured in 12 different brain regions from 60 brains in the Consortium Collection from the Stanley Medical Research Institute combined with microarray data and statistical tools. Fifteen brains each are from patients diagnosed with schizophrenia, bipolar disorder, or major depression, and unaffected controls. The four groups are matched by age, sex, race, postmortem interval, pH, side of brain, and mRNA quality. A Repository of raw data is also included. Users must register for access.schizophrenia, bipolar disorder, depressive disorder, brain, blinded study, microarray, single-nucleotide polymorphism, mental disorder, biomarkerSCR_002749(Stanley Neuropathology Consortium Integrative Database, RRID:SCR_002749)Stanley Medical Research Institute Schizophrenia, Bipolar Disorder, Depressive Disorder, Mental disorderLast checked upnif-0000-24103
PIDFinderResource, analysis service resource, data analysis service, service resource, production service resourcePIDFinder is a tool for the exploration of the Primary Immunodeficiency Disease Ontology. Apart from browsing the knowledge contained in the ontology, it can also be used for the identification of PIDs based on a set of observed Phenotypes. The PidFinder web application is a developing prototype application that allows non-bioinformaticians to quickly view and use the knowledge contained in the Primary Immunodeficiency Disease Ontology. The application consists of a number of components: * The PIDFinder: allows the selection of a set of phenotypes and subsequently compares the set with the canonical set of phenotypes defined in the PID Ontology. The phenotypes, that can be selected are grouped by biomarker and are thus available in a number of different facets. Once phenotypes have been selected, the application compares them to canonical phenotypes associated with PIDs in the PID Ontology, by computing a semantic similarity measure. The similarity is determined using a Tanimoto Distance - the more closely related an observed phenotype is to a canonical ontology phenotype, the closer the calculated Tanimoto Distance is to 1 - with increasing dissimilarity, the Tanimoto Coefficient tends towards 0. * The Phenotype Explorer: a rudimentary browser for phenotypes currently contained in the PID Ontology. The browser allows the user to find phenotypes based on biomarker categories and provides some basic definitions (not all definitions are available at this stage) and disease association information. * A Heatmap comparing the phenotypic overlap of PIDs: In essence, the heatmap is a many-to-many comparison of the phenotypic overlap between all Primary Immunodeficiency Diseases contained in the PID Ontology. Again, overlap is calculated using a Tanimoto Distance. The heatmap is a matrix, plotting the Tanimoto coefficients for every PID/PID pair. Increased off-diagonal overlap between PIDs most likely indicates genes in the same pathway. * A Phenotype Frequency Visualization: The phenotype frequency visualization is a simple bar chart indicating how often a particular phenotype is associated with a Primary Immunodeficiency Disease in the Ontology. * A PID Expert map: All of the phenotypes and knowledge contained in the Primary Immunodeficiency Disease Ontology has been extracted from primary clinical or research literature. To construct the map, we have extracted the affiliations and locations of the authors of the literature sources and overlayed them on a map. The hope is that this will facilitate the identification of (local) experts on primary immunodeficiency diseases.phenotype, disease, immunodeficiency, biomarker, ontologySCR_005833(PIDFinder, RRID:SCR_005833)Primary Immunodeficiency Diseaserelated to: PIDO - Primary Immunodeficiency Disease OntologyLast checked downnlx_149343
DPDx: Laboratory Identification of Parasites of Public Health ConcernResource, topical portal, database, analysis service resource, material analysis service, image collection, data set, service resource, portal, production service resource, storage service resource, biomaterial analysis service, data repository, data or information resourceParasite-related portal including concise reviews of parasites and parasitic diseases, an image library, a review of recommended procedures for collecting, shipping, processing, and examining biologic specimens, and a diagnostic assistance function, in which laboratorians and other health professionals desiring assistance in parasite identification can ask questions and/or send digital images of specimens for expedited review and consultation with DPD staff. This assistance is free of charge. The portal is hoped to strengthen diagnosis of, and enhance the capacity to address the global problem of parasitic diseases, both in the United States and abroad. Potential DPDx applications include: * training and continuing education of laboratorians, using material collected by CDC or contributed by other institutions * provision to health facilities worldwide of diagnostic assistance by CDC staff backed up when needed by experts from other institutions * diagnostic quizzes for self-assessment of laboratorians skills * informal, early detection of unusually clustered, atypical or emerging parasitic diseasesblastocystis, diagnosis, diagnostic, disease, global, gnathostoma, health, life cycle, micrograph, parasite, parasitic disease, pneumocystis, public health, case study, morphology, comparative morphology, intestinal tract, blood-borne parasite, life-cycle, electron micrograph, diagnostic procedureSCR_002335(DPDx: Laboratory Identification of Parasites of Public Health Concern, RRID:SCR_002335)Centers for Disease Control and Prevention Parasitic diseaseLast checked upnif-0000-21126
COLT-CancerResource, data analysis service, production service resource, analysis service resource, database, service resource, data or information resourceThe COLT-Cancer database is a collection of shRNA dropout signatures profiles, covering ~16000 human genes, and derived from more than 70 Pancreatic, Ovarian and Breast human cancer cell-lines using the microarray detection platform developed in the COLT (CCBR-OICR Lentiviral Technology) facility at the Moffat Lab. All shRNA dropout profiles are freely available through download or queries via this website.gene, shrna profile, shrna, functional genetics, cancer, cell lineSCR_006485(COLT-Cancer, RRID:SCR_006485)University of Toronto; Ontario; Canada Pancreatic cancer, Ovarian cancer, Breast cancerCanada Foundation for Innovation, Canadian Institutes of Health Research, Ontario Institute for Cancer Research, Ontario Research Fund, Terry Fox Research InstitutePMID:22102578Last checked upnlx_149426
CardioVascular Research Grid (CVRG)Resource, data analysis service, production service resource, analysis service resource, service resource, storage service resource, atlas, image repository, data repository, data or information resourceInfrastructure for sharing cardiovascular data and data analysis tools. Human ExVivo heart data set and canine ExVivo normal and failing heart data sets are available. Canine hearts atlas and human InVivo atlases are available.human, heart, canine, ex vivo, in vivo, protein microarray, cardiomyopathy, electrocardiogram, heart fiber, data sharing, microarray, data analysis tool, data analysis, mri, diffusion magnetic resonance imaging, diffusion weighted imaging, dti, cardiovascular, source code, web service, imagingSCR_004472(CardioVascular Research Grid (CVRG), RRID:SCR_004472)Johns Hopkins University; Maryland; USA Normal, Failing heart, Cardiomyopathy, Ischemic cardiomyopathy, Non-ischemic cardiomyopathyNHLBIrelated to: Galaxy, XNAT - The Extensible Neuroimaging Archive Toolkit, NIH Data Sharing Repositories, recommended by: National Library of Medicine, BRAIN InitiativeLast checked upnlx_143758
Stem Cell CommonsResource, source code, database, analysis service resource, production service resource, data set, service resource, storage service resource, software resource, data repository, data or information resourceOpen source environment for sharing, processing and analyzing stem cell data bringing together stem cell data sets with tools for curation, dissemination and analysis. Standardization of the analytical approaches will enable researchers to directly compare and integrate their results with experiments and disease models in the Commons. Key features of the Stem Cell Commons * Contains stem cell related experiments * Includes microarray and Next-Generation Sequencing (NGS) data from human, mouse, rat and zebrafish * Data from multiple cell types and disease models * Carefully curated experimental metadata using controlled vocabularies * Export in the Investigation-Study-Assay tabular format (ISA-Tab) that is used by over 30 organizations worldwide * A community oriented resource with public data sets and freely available code in public code repositories such as GitHub Currently in development * Development of Refinery, a novel analysis platform that links Commons data to the Galaxy analytical engine * ChIP-seq analysis pipeline (additional pipelines in development) * Integration of experimental metadata and data files with Galaxy to guide users to choose workflows, parameters, and data sources Stem Cell Commons is based on open source software and is available for download and development.therapeutic target, blood, stem cell, self-renewal, embryonic stem cell, hematopoietic stem cell, leukemia stem cell, gene, protein, phenotype, therapeutic, annotate, share, analyze, data sharing, statistics, visualize, analyze, microarray, next-generation sequencing, statistics, transcription profiling, genome, genome browser, disease modelSCR_004415(Stem Cell Commons, RRID:SCR_004415)Harvard Stem Cell Institute Normal, Acute Myelogenous Leukemia, Glioblastoma, Primitive Neuroectodermal Tumor, Etc.related to: Galaxy, ISA Infrastructure for Managing Experimental MetadataLast checked upnlx_42085http://bloodprogram.hsci.harvard.edu/
Human Developmental Biology ResourceResource, material analysis service, analysis service resource, biomaterial supply resource, production service resource, tissue bank, service resource, biomaterial analysis service, material resourceCollection of human embryonic and fetal material (Tissue and RNA) ranging from 3 to 20 weeks of development available to the international scientific community. Material can either be sent to registered users or our In House Gene Expression Service (IHGES) can carry out projects on user''''s behalf, providing high quality images and interpretation of gene expression patterns. Gene expression data emerging from HDBR material is added to our gene expression database which is accessible via our HUDSEN (Human Developmental Studies Network) website. A significant proportion of the material has been cytogenetically karyotyped, and normal karyotyped material is provided for research.development, fetal material, fetus, embryonic human, fetus human, karyotype, gene expression, image, imagingSCR_006326(Human Developmental Biology Resource, RRID:SCR_006326) University College London; London; United Kingdom , Newcastle University; Newcastle upon Tyne; United Kingdom NormalMRC, Wellcome Trustrelated to: HUDSEN Human Gene Expression Spatial Database, listed by: One Mind Biospecimen Bank ListingLast checked upnlx_152030
Comprehensive Neuroscience CenterResource, organization portal, production service resource, analysis service resource, behavioral analysis service, portal, service resource, data or information resourceTHIS RESOURCE IS NO LONGER IN SERVICE, documented on July 08, 2014. A multi-disciplinary institute providing specialized diagnostic evaluations, innovative treatments, education and research. It provides a collaborative, team-centered approach to provide innovative diagnostics to assist in developing cutting-edge brain based interventions and treatment strategies to best serve their patient's individual needs. Comprehensive Neuroscience Center is dedicated to working with children and adults who demonstrate neurodevelopmental disorders such as Autism Spectrum Disorders, Attention Deficits Hyperactivity Disorder, Learning Disabilities and Language-based deficits, as well as other neurological-based disorders including Traumatic brain injury, Disorders of Consciousness, Disorders of Aging, Alzheimer's and Dementia.neuroscience, treatment, diagnostics, diagnosis, neurodevelopmental, disorder, autism, hyperactivty, disability, neurological, traumatic brain injury, consciousness, alzheimer's, dementia, adult human, child, interventionSCR_008705(Comprehensive Neuroscience Center, RRID:SCR_008705)Neurodevelopmental disorder, Autism Spectrum Disorder, Attention deficit-hyperactivity disorder, Learning Disability, Language-based deficit, Neurological-based disorder, Traumatic brain injury, Disorder of Consciousness, Disorder of Aging, Alzheimer's disease, DementiaLast checked downnif-0000-37854
CODR: C PATH On Line Data RepositoryResource, data analysis service, database, analysis service resource, production service resource, service resource, storage service resource, data repository, data or information resourceA repository of de-identified control arm data of patients from clinical studies of Alzheimer's disease and Mild Cognitive Impairment. It provides the ability to analyze the data online with the R statistical analysis program, create and download standard reports, run complex queries, or download data to a desktop for further analysis. Additional data will be added to the database over time. Critical Path Institute consortia members and qualified researchers may upload and work on scientific data relevant to biomarkers of drug toxicity, neurodegenerative diseases, and patient-reported outcomes.clinical data, alzheimer's disease, camd, biomarker, drug toxicity, neurodegenerative disease, patient-reported outcome, patient outcome, metadata standard, data repositorySCR_001388(CODR: C PATH On Line Data Repository, RRID:SCR_001388)CAMD Neurodegenerative disease, Drug toxicity, Alzheimer's disease, Mild Cognitive ImpairmentLast checked upnlx_152562
La Jolla Interdisciplinary Neurosciences CenterResource, production service resource, analysis service resource, material analysis service, material service resource, service resource, access service resource, biomaterial analysis serviceOur NINDS Center Core Grant supports centralized resources and facilities shared by investigators with existing NINDS-funded research projects. Our Center is composed of three research cores, each of which will enrich the effectiveness of ongoing research, and promote new research directions. The three Core facilities support Electrophysiology, Neuropathology / Histology, and High-Throughput/High-Content Chemical and Genomic Library screening. By making these important Core Services available to the local Neuroscience community, the La Jolla Neurosciences Program hopes to promote the study of how the nervous system works and develop treatments for nervous system diseases. The cores and their services are available to La Jolla neuroscientists. Core services are available to NINDS-supported neuroscience projects from local investigators as well as young neuroscientists prior to obtaining their first NIH-funded grant. * Electrophysiology: SBMRI Electrophysiology ** The Electrophysiology Core consists of the Sanford-Burnham Electrophysiology Facility. This facility can perform patch-clamp intracellular and extracellular field recordings on a range of material including cultured cells and brain slices. The Sanford-Burnham facility emphasizes electrophysiological analysis of cultured cells and the detailed electrical properties of channels, receptors and recombinant proteins expressed in Xenopus oocytes or mammalian cells. * Neuropathology: UCSD Neuropathology ** The Neuropathology laboratory applies immunocytochemistry, neurochemistry, molecular genetics, transgenic models of disease, and imaging by scanning laser confocal microscopy to analysis of neurological disease in animal models. * Chemical Library Screening: SBIMR Assay Development, SBIMR Chemical Library Screening, SBIMR Cheminformatics, SBIMR High-content Screening ** The Chemical Library Screening core offers high-throughput screening (HTS) of biochemical and cell-based array using traditional HTS readouts and automated microscopy for high-content screening (HCS)> These facilities also offer array development and screening, as well as cheminformatics and medicinal chemistry.neuroscience, nervous system, electrophysiology, neuropathology, histology, high-throughput screening, high-content screening, chemical, genomic, chemical library screening, cheminformatics, medicinal chemistrySCR_002772(La Jolla Interdisciplinary Neurosciences Center, RRID:SCR_002772) Sanford Burnham Prebys Medical Discovery Institute , University of California at San Diego; California; USA Nervous system diseaseNIH Blueprint for Neuroscience Research, NINDSLast checked upnif-0000-00436
SeqWright BiorepositoryResource, commercial organization, production service resource, analysis service resource, biomaterial supply resource, material analysis service, tissue bank, service resource, storage service resource, biomaterial analysis service, material resource, material storage repositoryConvenient, cost-effective and reliable storage solutions including maintaining, storing and monitoring your biological samples. Avoid costly purchases of ultra-low temperature freezers, sample tracking LIMS, and layers of emergency back-up infrastructure. Enjoy peace of mind in the knowledge that your critical samples are safe, secure, and readily available to you. Service Features * Real-time sample tracking and monitoring, with 24/7 accessibility. * GLP compliant repository with cold chain of custody. * Numerous storage options, from ambient temperature to -170 degrees C. * Hazardous specimen storage capabilities. * Redundant emergency back-up systems. * Secure-access facility. * At Temperature back-up freezers. * Rapid domestic & international shipping. As a full-service contract genomics provider, SeqWright is able to offer our BioRepository customers the additional benefit of a broad portfolio of regulated services for testing of samples, as and when required, and then returning the samples back to our BioRepository for further storage. Contact us for your customized solution.storage, hazardous specimen, biospecimen, frozen, ambient temperatureSCR_004657(SeqWright Biorepository, RRID:SCR_004657)N/Alisted by: One Mind Biospecimen Bank ListingLast checked upnlx_65768
Movement Disorders BiobankResource, material analysis service, analysis service resource, biomaterial supply resource, production service resource, service resource, storage service resource, biomaterial analysis service, material resource, material storage repositoryA biobank of human biological material and genetic information. It provides samples and information to researchers in order to identify new genes and clarify pathogenic mechanisms of diseases. The biobank offers biochemical and molecular diagnoses of genetic dystonias, Parkinson's disease and NBIA disorders, as well as storage of biological samples for external institutions.dna, fibroblast, movement disorder, neurodegeneration, brain iron accumulation disorder, dystonia, parkinson's disease, phenotype, genotype, gene, biobankSCR_010659(Movement Disorders Biobank, RRID:SCR_010659)EuroBioBank Movement disorder, Neurodegeneration with Brain Iron Accumulation disorder, Dystonia, Parkinson's diseaserelated to: EuroBioBank, listed by: One Mind Biospecimen Bank ListingLast checked upnlx_69108http://www.istituto-besta.it/Area-Ricerca.aspx?doc=Elenco-Unita-Operative&IdUO=UO-NEUROGENETICAMOLECOLARE
InnateDBResource, data analysis service, production service resource, analysis service resource, database, service resource, data or information resourcePublicly available database of the genes, proteins, experimentally-verified interactions and signaling pathways involved in the innate immune response of humans, mice and bovines to microbial infection. The database captures coverage of the innate immunity interactome by integrating known interactions and pathways from major public databases together with manually-curated data into a centralized resource. The database can be mined as a knowledgebase or used with the integrated bioinformatics and visualization tools for the systems level analysis of the innate immune response. Although InnateDB curation focuses on innate immunity-relevant interactions and pathways, it also incorporates detailed annotation on the entire human, mouse and bovine interactomes by integrating data (178,000+ interactions & 3,900+ pathways) from several of the major public interaction and pathway databases. InnateDB also has integrated human, mouse and bovine orthology predictions generated using Ortholgue software. Ortholgue uses a phylogenetic distance-based method to identify possible paralogs in high-throughput orthology predictions. Integrated human and mouse conserved gene order and synteny information has also been determined to provide further support for orthology predictions. InnateDB Capabilities: * View statistics for manually-curated innate immunity relevant molecular interactions. New manually curated interactions are submitted weekly. * Search for genes and proteins of interest. * Search for experimentally-verified molecular interactions by gene/protein name, interaction type, cell type, etc. * Search genes/interactions belonging to 3,900 pathways. * Visualize interactions using an intuitive subcellular localization-based layout in Cerebral. * Upload your own list of genes along with associated gene expression data (from up to 10 experimental conditions) to interactively analyze this data in a molecular interaction network context. Once you have uploaded your data, you will be able to interactively visualize interaction networks with expression data overlaid; carry out Pathway, Gene Ontology and Transcription Factor Binding Site over-representation analyses; construct orthologous interaction networks in other species; and much more. * Access curated interaction data via a dedicated PSICQUIC webservice.gene, immune response, pathway, protein, signaling pathway, interaction, immune, signaling response, gene, orthology prediction, orthology, ortholg, annotation, interactome, gene expression, molecule, protein-protein interaction, molecular interaction, visualization, nucleic acid-protein, nucleic acid, network, web service, transcription factor binding site, software resourceSCR_006714(InnateDB, RRID:SCR_006714)Simon Fraser University; British Columbia; Canada , University of British Columbia; British Columbia; Canada Microbial infection, Allergy, AsthmaAllerGen, European Union, Michael Smith Foundation for Health Research, Teagascrelated to: IMEx - The International Molecular Exchange Consortium, Interaction Reference Index, ConsensusPathDB, IMEx - The International Molecular Exchange Consortium, PSICQUIC Registry, PSICQUIC, Gene Ontology, IntAct, listed by: re3data.org, works_with: IMEx - The International Molecular Exchange ConsortiumReferences (2)Last checked upnif-0000-20808
SumsDBResource, data analysis service, database, analysis service resource, production service resource, service resource, storage service resource, atlas, image repository, data repository, data or information resourceTHIS RESOURCE IS NO LONGER IN SERVICE, documented on May 11, 2016. Repository of brain-mapping data (surfaces and volumes; structural and functional data) derived from studies including fMRI and MRI from many laboratories, providing convenient access to a growing body of neuroimaging and related data. WebCaret is an online visualization tool for viewing SumsDB datasets. SumsDB includes: * data on cerebral cortex and cerebellar cortex * individual subject data and population data mapped to atlases * data from FreeSurfer and other brainmapping software besides Caret SumsDB provides multiple levels of data access and security: * Free (public) access (e.g., for data associated with published studies) * Data access restricted to collaborators in different laboratories * Owner-only access for work in progress Data can be downloaded from SumsDB as individual files or as bundles archived for offline visualization and analysis in Caret WebCaret provides online Caret-style visualization while circumventing software and data downloads. It is a server-side application running on a linux cluster at Washington University. WebCaret "scenes" facilitate rapid visualization of complex combinations of data Bi-directional links between online publications and WebCaret/SumsDB provide: * Links from figures in online journal article to corresponding scenes in WebCaret * Links from metadata in WebCaret directly to relevant online publications and figuressegmentation, volume, neuroimaging, brain, fmri, stereotaxic foci, stereotaxic coordinate, brain-mapping, foci, structural mri, mri, cerebral cortex, cerebellar cortex, afni brik, analyze, atlas, nifti, registration, rendering, spatial transformation, surface analysis, surface rendering, visualization, volume rendering, brain mapping, neuroanatomySCR_002759(SumsDB, RRID:SCR_002759)Washington University School of Medicine in St. Louis; Missouri; USA Mental disease, Neurological disorder, NormalHuman Brain Project, NASA, National Partnership for Advanced Computational Infrastructure, NCI, NIMH, NLM, NSFrelated to: Computerized Anatomical Reconstruction and Editing Toolkit, Integrated Manually Extracted Annotation, used by: NIF Data Federation, listed by: Biositemaps, NeuroImaging Tools and Resources Collaboratory (NITRC), re3data.orgLast checked downnif-0000-00016http://brainvis.wustl.edu/wiki/index.php/Sums:About http://www.nitrc.org/projects/sumsdb
Psychiatric Genomics ConsortiumResource, organization portal, computational hosting, production service resource, analysis service resource, consortium, service resource, portal, data analysis service, storage service resource, data repository, community building portal, data or information resourceConsortium conducting meta-analyses of genome-wide genetic data for psychiatric disease. Focused on autism, attention-deficit hyperactivity disorder, bipolar disorder, major depressive disorder, schizophrenia, anorexia nervosa (AN), Tourette syndrome (TS), and obsessive-compulsive disorder (OCD). Used to investigate common single nucleotide polymorphisms (SNPs) genotyped on commercial arrays, structural variation (copy number variation) and uncommon or rare genetic variation. To participate you are asked to upload data from your study to central computer used by this consortium. Genetic Cluster Computer serves as data warehouse and analytical platform for this study . When data from your study have been incorporated, account will be provided on central server and access to all GWAS genotypes, phenotypes, and meta-analytic results relevant to deposited data and participation aims. NHGRI GWAS Catalog contains updated information about all GWAS in biomedicine, and is usually excellent starting point to find comprehensive list of studies. Files can be obtained by any PGC member for any disease to which they contributed data. These files can also be obtained by application to NIMH Genetics Repository. Individual-level genotype and phenotype data requires application, material transfer agreement, and informed consent consideration. Some datasets are also in controlled-access dbGaP and Wellcome Trust Case-Control Consortium repositories. PGC members can also receive back cleaned and imputed data and results for samples they contributed to PGC analyses.structural variation, genetic variation, single nucleotide polymorphism, attention deficit-hyperactivity disorder, bipolar disorder, schizophrenia, mental disease, one mind ptsd, data sharing, visualization, genome-wide association study, genomic, genotype, phenotype, psychiatry, gwas, copy number variationSCR_004495(Psychiatric Genomics Consortium, RRID:SCR_004495)University of North Carolina at Chapel Hill; North Carolina; USA Mental disease, Attention deficit-hyperactivity disorder, Bipolar Disorder, Schizophrenia, Major Depressive Disorder, Autism, Cross-disorderHersenstichting Nederland, Netherlands Genetic Cluster Computer, NIMHrelated to: Ricopili, GWAS: Catalog of Published Genome-Wide Association Studies, NCBI database of Genotypes and Phenotypes, Wellcome Trust Case Control ConsortiumReferences (5)Last checked downnlx_143769https://pgc.unc.edu/
Kidney and Urinary Pathway Knowledge BaseResource, data analysis service, production service resource, analysis service resource, data set, service resource, storage service resource, data repository, data or information resourceA collection of omics datasets (mRNA, proteins and miRNA) that have been extracted from PubMed and other related renal databases, all related to kidney physiology and pathology giving KUP biologists the means to ask queries across many resources in order to aggregate knowledge that is necessary for answering biological questions. Some microarray raw datasets have also been downloaded from the Gene Expression Omnibus and analyzed by the open-source software GeneArmada. The Semantic Web technologies, together with the background knowledge from the domain's ontologies, allows both rapid conversion and integration of this knowledge base. SPARQL endpoint http://sparql.kupkb.org/sparql The KUPKB Network Explorer will help you visualize the relationships among molecules stored in the KUPKB. A simple spreadsheet template is available for users to submit data to the KUPKB. It aims to capture a minimal amount of information about the experiment and the observations made.kidney, urinary, urine, pathway, molecule, visualizer, gene, protein, mirna, metabolite, mrna, microarray, ortholog, rdf, renal cell, anatomy, animal model, disease, sparql, proteomics, ontology, biomarker, gene expression, physiology, pathologySCR_001746(Kidney and Urinary Pathway Knowledge Base, RRID:SCR_001746)University of Manchester; Manchester; United Kingdom , National Institute of Health and Medical Research; Rennes; France Kidney diseaseEuropean Union, FP7, ICT-2007.4.4 e-LICO projectrelated to: NIDDK Information Network, Gene Expression Omnibus, Gene Ontology, KEGG, submitted by: NIDDK Information NetworkPMID:21624162Last checked downnlx_154134http://www.e-lico.eu/kupkb
Project HOPEResource, source code, data analysis service, production service resource, analysis service resource, service resource, software resourceAn easy-to-use webserver that analyses the structural effects of your mutation of interest. The server allows you to submit a protein sequence and the mutation. Project HOPE will then collect and combine available information from a series of webservers and databases and will produce a mutation report complete with results, figures and animations. Where available Project HOPE will use the 3D structure of the protein but the server can also build a homology model if necessary. Other information sources include the Uniprot database and a series of DAS prediction servers.protein structure, mutationSCR_005141(Project HOPE, RRID:SCR_005141)Radboud University; Nijmegen; The Netherlands Inheritable diseaselisted by: OMICtoolsPMID:21059217Last checked downOMICS_00130
Influenza Research Database (IRD)Resource, data analysis service, database, analysis service resource, production service resource, service resource, storage service resource, data repository, data or information resourceThe Influenza Research Database (IRD) serves as a public repository and analysis platform for flu sequence, experiment, surveillance and related data.avian, clinical, genomic, host, influenza, isolate, mammalian, nonhuman, phenotypic, preventive, proteomic, repository, strain, epitope, surveillance, treatment, virus, protein sequence, immune, 3d protein structure, align, blast, short peptide, flu protein, sequence variation, snp, phylogenetic tree, human, 3d spacial image, image, clinical data, clinical, genomic, proteomic, phenotypeSCR_006641(Influenza Research Database (IRD), RRID:SCR_006641) Los Alamos National Laboratory , University of Texas Southwestern Medical Center; Texas; USA , Sage Analytica Influenza virus, InfluenzaNIAIDrelated to: Los Alamos National Laboratory, University of California at Davis, California, USA, Sage Analytica, J. Craig Venter InstitutePMID:17965094Last checked downnif-0000-21222
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