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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

(last updated: Aug 10, 2019)

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Resource NameResource TypeDescriptionKeywordsResource IDProper CitationParent OrganizationRelated ConditionFunding AgencyRelationReferenceWebsite StatusAlternate IDsAlternate URLsOld URLs
Laser Biomedical Research CenterResource, biomedical technology research center, service resource, access service resource, training resourceBiomedical technology research center that develops the basic scientific understanding and new techniques required for advancing the clinical applications of lasers and spectroscopy. To fulfill the need for a more comprehensive and potentially non-invasive understanding of the human body, the LBRC merges optical spectroscopy, imaging, scattering, and interferometry techniques. Specifically, researchers at the LBRC study the biophysics and biochemistry of healthy and diseased biological structures from the subcellular to the entire-organ scale. For example, spectral diagnosis instruments based on near-infrared Raman scattering, intrinsic fluorescence, diffuse reflectance, and single light scattering provide complementary data on human disease. Combining these techniques into a single, multimodal instrument is applied for diagnostics in various organs, including cervix, oral cavity, Barrett's esophagus, artery, breast, skin, as well as for transcutaneous measurements of blood constituents. The LBRC has been and continues to be a pioneer in the field of developing novel optical probes for use under direct visualization or with endoscopes and biopsy devices. Similarly, new microscopy tools based on interferometry are designed and exploited for measuring cellular structures and their dynamics. In particular, these techniques provide the crucial and unique ability to non-invasively study cells in their native states at remarkably high spatial and temporal resolutions. Using these novel microscopy tools, the LBRC has conducted critical studies to elucidate the fundamental biology of diseases as diverse as malaria and multiple myeloma, and physiological processes such as cell growth and cell division. The interferometry concepts have also been vital in Center's research efforts to develop optical tools for deep-tissue imaging while minimizing the adverse effects of light scattering or diffusion. Furthermore, the unique and powerful combination of the interferometric microscopy and vibrational spectroscopy tools adds a hitherto unexplored dimension to optical sensing by simultaneous probing of morphological and chemical information. A unique feature of the LBRC is its ability to form strong clinical collaborations with outside investigators in areas of common interest that further the Center's mandated research objectives. As a National Research Resource Center, the LBRC makes available its facilities, along with technical and scientific support, to outside researchers for the purpose of pursuing independent research projects in the area of laser biomedical applications. The facilities are available on a time-shared basis, free-of-cost policy to qualified scientists, engineers and physicians throughout the United States.spectroscopy, laser, biomedicine, optical spectroscopy, imaging, scattering, interferometry, optical probe, microscopySCR_000106(Laser Biomedical Research Center, RRID:SCR_000106)Massachusetts Institute of Technology; Massachusetts; USA Pre-cancer, Cancer, Atherosclerosis, Healthy, DiseasedNIBIBLast checked upnlx_152645
KI Biobank - PAINResource, disease-related portal, topical portal, research forum portal, biomaterial supply resource, portal, material resource, data or information resourceTHIS RESOURCE IS NO LONGER IN SERVICE, documented August 29, 2016. Aims to investigate the relation between specific genetic variations, personality factors and pain experience in healthy subjects.genetic variation, personality factor, pain, gene, personalitySCR_000610(KI Biobank - PAIN, RRID:SCR_000610)Karolisnka Biobank Healthylisted by: One Mind Biospecimen Bank ListingLast checked downnlx_149607
Center for EPR Imaging in Vivo PhysiologyResource, biomedical technology research center, training resourceBiomedical technology research center that develops instrumentation, analysis techniques, spin probes and spin traps, and methodologies for imaging physiologically relevant aspects of tissue fluids, including high-resolution oxygen maps, with very low frequency electron paramagnetic resonance imaging (EPRI). Novel bridges and high-access, low-field magnet/gradient systems have produced physiologically relevant measurements and accommodate a number of resonant structures. The Center is a consortium between the University of Chicago, the University of Denver, the University of Maryland and Novosibirsk Institute of Organic Chemistry (NIOC), Russia.electron paramagnetic resonance, in vivo, spin probeSCR_001410(Center for EPR Imaging in Vivo Physiology, RRID:SCR_001410)University of Chicago; Illinois; USA Diseased, HealthyNIBIBLast checked downnlx_152632
BraVaResource, data or information resource, databaseA database of digital reconstructions of the human brain arterial arborizations from 61 healthy adult subjects along with extracted morphological measurements. The arterial arborizations include the six major trees stemming from the circle of Willis, namely: the left and right Anterior Cerebral Arteries (ACAs), Middle Cerebral Arteries (MCAs), and Posterior Cerebral Arteries (PCAs).digital reconstruction, morphometric analysis, cerebrum, arterial vasculature, magnetic resonance angiography, adult human, morphology, artery, arborization, circle of willis, cerebral artery, male, female, magnetic resonanceSCR_001407(BraVa, RRID:SCR_001407)George Mason University: Krasnow Institute for Advanced Study HealthyNIBIB, NIMH, NINDSrelated to: Bravissima, listed by: NITRCPMID:23727319Last checked upnlx_152630http://www.nitrc.org/projects/breva
anageResource, data or information resource, databaseA curated database of aging and life history in animals, including extensive longevity records and complementary traits for > 4000 vertebrate species. AnAge was primarily developed for comparative biology studies, in particular studies of longevity and aging, but can also be useful for ecological and conservation studies and as a reference for zoos and field biologists.senescence, comparative biology, longevitySCR_001470(anage, RRID:SCR_001470)Human Ageing Genomic Resources Healthy aging, Aging, Healthyused by: Aging Portal, NIF Data FederationPMID:23193293Last checked upnlx_152700
Harvard - Oxford Cortical Structural AtlasResource, atlas, reference atlas, data or information resourceProbabilistic atlases covering 48 cortical and 21 subcortical structural areas, derived from structural data and segmentations kindly provided by the Harvard Center for Morphometric Analysis. T1-weighted images of 21 healthy male and 16 healthy female subjects (ages 18-50) were individually segmented by the CMA using semi-automated tools developed in-house. The T1-weighted images were affine-registered to MNI152 space using FLIRT (FSL), and the transforms then applied to the individual labels. Finally, these were combined across subjects to form population probability maps for each label. Segmentations used to create these atlases were provided by: David Kennedy and Christian Haselgrove, Centre for Morphometric Analysis, Harvard; Bruce Fischl, the Martinos Center for Biomedical Imaging, MGH; Janis Breeze and Jean Frazier from the Child and Adolescent Neuropsychiatric Research Program, Cambridge Health Alliance; Larry Seidman and Jill Goldstein from the Department of Psychiatry of Harvard Medical School.male, female, t1-weighted image, cortical, subcortical, neuroanatomy, cortexSCR_001476(Harvard - Oxford Cortical Structural Atlas, RRID:SCR_001476)Harvard University; Cambridge; United States HealthyNCRR, NIMH, NINDSLast checked upnlx_152707
Beijing: Eyes Open Eyes Closed StudyResource, data set, data or information resourceData set of 48 healthy controls from a community (student) sample from Beijing Normal University in China with 3 resting state fMRI scans each. During the first scan participants were instructed to rest with their eyes closed. The second and third resting state scan were randomized between resting with eyes open versus eyes closed. In addition this dataset contains a 64-direction DTI scan for every participant. The following data are released for every participant: * 6-minute resting state fMRI scan (R-fMRI) * MPRAGE anatomical scan, defaced to protect patient confidentiality * 64-direction diffusion tensor imaging scan (2mm isotropic) * Demographic information and information on the counterbalancing of eyes open versus eyes closed.early adult human, resting state, fmri, diffusion tensor imaging, resting state fmri, eyes open, eyes closed, neuroimaging, mprage, image collection, brainSCR_001507(Beijing: Eyes Open Eyes Closed Study, RRID:SCR_001507) 1000 Functional Connectomes Project , Beijing Normal University; Beijing; China HealthyNational High Technology Program of China (863), National Natural Science Foundation of Chinalisted by: NITRCLast checked downnlx_152810
MIRIADResource, data or information resource, databaseA database of volumetric MRI brain-scans of 46 Alzheimer's sufferers and 23 healthy elderly people. Many scans were collected of each participant at intervals from 2 weeks to 2 years, the study was designed to investigate the feasibility of using MRI as an outcome measure for clinical trials of Alzheimer's treatments. It includes a total of 708 scans and should be of particular interest for work on longitudinal biomarkers and image analysis.magnetic resonance, late adult human, longitudinal, mri, mini mental state examinationSCR_002422(MIRIAD, RRID:SCR_002422)University College London; London; United Kingdom Alzheimer's disease, Healthy, Late adult humanComprehensive Biomedical Research Centre Strategic Investment Award Ref. 168, EPSRC EP/H046410/1, GlaxoSmithKline, MRC, National Institute for Health Research, UK Alzheimers Societyrelated to: XNAT - The Extensible Neuroimaging Archive Toolkit, listed by: NITRCPMID:23274184Last checked upnlx_155795http://www.nitrc.org/projects/miriad
Multi-Modal MRI Reproducibility ResourceResource, image collection, data or information resourceScan-rescan imaging sessions on 21 healthy volunteers (no history of neurological disease) intended to be a resource for statisticians and imaging scientists to be able to quantify the reproducibility of their imaging methods using data available from a generic 1 hour session at 3T. Imaging modalities include MPRAGE, FLAIR, DTI, resting state fMRI, B0 and B1 field maps, ASL, VASO, quantitative T1 mapping, quantitative T2 mapping, and magnetization transfer imaging. All data have been converted to NIFTI format. Please cite: Bennett. A. Landman, Alan J. Huang, Aliya Gifford, Deepti S. Vikram, Issel Anne L. Lim, Jonathan A.D. Farrell, John A. Bogovic, Jun Hua, Min Chen, Samson Jarso, Seth A. Smith, Suresh Joel, Susumu Mori, James J. Pekar, Peter B. Barker, Jerry L. Prince, and Peter C.M. van Zijl. ?Multi-Parametric Neuroimaging Reproducibility: A 3T Resource Study?, NeuroImage. (2010) NIHMS/PMC:252138 doi:10.1016/j.neuroimage.2010.11.047java image science toolkit, magnetic resonance, nifti, neuroimaging, reproducibility, mprage, flair, dti, resting state fmri, b0 field map, b1 field map, asl, vaso, quantitative t1 mapping, quantitative t2 mapping, magnetization transfer imagingSCR_002442(Multi-Modal MRI Reproducibility Resource, RRID:SCR_002442)Healthyrelated to: JIST: Java Image Science Toolkit, listed by: NITRCPMID:21094686Last checked upnlx_155818
Ear LabResource, laboratory portal, portal, organization portal, data or information resourceA computationally oriented experimental laboratory interested in the encoding of auditory information in the cerebral cortex and brainstem, and in the mechanisms of tinnitus and the effect of various drugs (Lidocaine, steroids, anti-oxidants) in relieving noise trauma induced tinnitus. The ferret (Mustela putorius) and the rat serve as their system model. Through chronic implants, they obtain electrophysiological data from awake behaving animals in order to investigate the response properties and functional organization of the auditory system, both in health and after noise trauma that induces tinnitus in rats. Projects: * Response Modulation to Ongoing Broadband Sounds in Primary Auditory Cortex * Neuronal Response Characteristics in the Inferior Colliculus of the Awake Ferret and Rat * Spectro-Temporal Representation of Feature Onsets in Primary Auditory Cortex * Targeting the changes in inferior colliculus induced by tinnitusear, auditory, cerebral cortex, behavior, health, noise, trauma, research, engineering, primary auditory cortex, neuron, brainstem, tinnitus, drug, lidocaine, steroid, anti-oxidant, computation, auditory system, sound, mustela putorius, inferior colliculusSCR_002531(Ear Lab, RRID:SCR_002531)University of Maryland; Maryland; USA Tinnitus, HealthyLast checked upnif-0000-00404
Arredondo ANT fNIRS dataset1Resource, data set, data or information resourceTHIS RESOURCE IS NO LONGER AVAILABLE. Documented September 12, 2017.\\n\\nDataset in Bilingual exposure optimizes left-hemisphere dominance for selective attention processes in the developing brain by Arredondo, Su, Satterfield, & Kovelman (XX) Does early bilingual exposure alter the representations of cognitive processes in the developing brain? Theories of bilingual development have suggested that bilingual language switching might improve children''s executive function and foster the maturation of prefrontal brain regions that support higher cognition. To test this hypothesis, we used functional Near Infrared Spectroscopy to measure brain activity in Spanish-English bilingual and English-monolingual children during a visuo-spatial executive function task of attentional control (N=27, ages 7-13). Prior findings suggest that while young children start with bilateral activation for the task, it becomes right-lateralized with age (Konrad et al., 2005). Indeed monolinguals showed bilateral frontal activation, however young bilinguals showed greater activation in left language areas relative to right hemisphere and relative to monolinguals. The findings suggest that bilingual experience optimizes attention mechanisms in the language hemisphere, and highlight the importance of early experiences for neurodevelopmental plasticity of higher cognition. These data are made available from Ioulia Kovelman''s Language and Literacy Lab at University of Michigan and may be exported through the NIF Data Federation. To cite these data please use this text Data were published by Arredondo et al. (XX) and made available via the NIF at XXattention, functional near infrared spectroscopy, fnirs, bilingualism, language, child, ant, developing, brainSCR_002653(Arredondo ANT fNIRS dataset1, RRID:SCR_002653)University of Michigan; Michigan; USA Healthyused by: NIF Data FederationLast checked upnlx_156086
Cardiovascular Model RepositoryResource, image collection, data set, service resource, storage service resource, data repository, data or information resourceRepository of geometric models collected from on-going and past research projects in the Cardiovascular Biomechanics Research Laboratory at Stanford University. The geometric models are mostly built from imaging data of healthy and diseased individuals. For each of the models, a short description is given with a reference. The geometric models are in VTK PolyData XML .vtp format. * Audience: Biomechanical and computational researchers interested in complex models of cardiovascular applications * Long Term Goals and Related Uses: Allow users to download geometric models for cardiovascular applications. These geometric models can be used for research purposes, such as meshing and scientific visualization. Users are welcome to contact the project administrator, join the project and contribute additional models.aneurysm, arteriofemoral bypass, cardiovascular simulation, image-based geometric modeling, simvascular, stent, vtk, healthy, diseased, normal, cardiovascular, model, cardiovascular model, cardiovascular system, bypass, palmaz-stent, aorta, source codeSCR_002679(Cardiovascular Model Repository, RRID:SCR_002679)Simtk.org Normal, Cardiovascular disease, Healthylisted by: BiositemapsLast checked upnif-0000-23301
brainmap.orgResource, software resource, software application, data or information resource, databaseA community database of published functional and structural neuroimaging experiments with both metadata descriptions of experimental design and activation locations in the form of stereotactic coordinates (x,y,z) in Talairach or MNI space. BrainMap provides not only data for meta-analyses and data mining, but also distributes software and concepts for quantitative integration of neuroimaging data. The goal of BrainMap is to develop software and tools to share neuroimaging results and enable meta-analysis of studies of human brain function and structure in healthy and diseased subjects. It is a tool to rapidly retrieve and understand studies in specific research domains, such as language, memory, attention, reasoning, emotion, and perception, and to perform meta-analyses of like studies. Brainmap contains the following software: # Sleuth: database searches and Talairach coordinate plotting (this application requires a username and password) # GingerALE: performs meta-analyses via the activation likelihood estimation (ALE) method; also converts coordinates between MNI and Talairach spaces using icbm2tal # Scribe: database entry of published functional neuroimaging papers with coordinate results3d model, atlas, data management, imaging, map, neuroinformatics, warping, neuroimaging, brain, talairach, mni, java, modeling, magnetic resonance, nifti-1, ontology, os independent, pet, spect, visualization, functional neuroimaging, fmriSCR_003069(brainmap.org, RRID:SCR_003069)University of Texas Health Science Center at San Antonio; Texas; USA Healthy, DiseasedNIMHrelated to: Brede Database, uses: Scribe, listed by: NITRCReferences (3)Last checked upnif-0000-00049http://www.nitrc.org/projects/brainmap
CCHMC Pediatric Brain TemplatesResource, atlas, image collection, reference atlas, data or information resourceBrain imaging data collected from a large population of normal, healthy children that have been used to construct pediatric brain templates, which can be used within statistical parametric mapping for spatial normalization, tissue segmentation and visualization of imaging study results. The data has been processed and compiled in various ways to accommodate a wide range of possible research approaches. The templates are made available free of charge to all interested parties for research purposes only. When processing imaging data from children, it is important to take into account the fact that the pediatric brain differs significantly from the adult brain. Therefore, optimized processing requires appropriate reference data be used because adult reference data will introduce a systematic bias into the results. We have shown that, in the in the case of spatial normalization, the amount of non-linear deformation is dramatically less when a pediatric template is used (left, see also HBM 2002; 17:48-60). We could also show that tissue composition is substantially different between adults and children, and more so the younger the children are (right, see also MRM 2003; 50:749-757). We thus believe that the use of pediatric reference data might be more appropriate.brain, child, human, normal, pediatric, spatial normalization, template, tissue segmentation, visualization, young human, neuroimagingSCR_003276(CCHMC Pediatric Brain Templates, RRID:SCR_003276)Normal, Healthyrelated to: SPMLast checked upnif-0000-01274
NIH MRI Study of Normal Brain DevelopmentResource, data set, narrative resource, experimental protocol, data or information resourceData sets of clinical / behavioral and image data are available for download by qualified researchers from a seven year, multi-site, longitudinal study using magnetic resonance technologies to study brain maturation in healthy, typically-developing infants, children, and adolescents and to correlate brain development with cognitive and behavioral development. The information obtained in this study is expected to provide essential data for understanding the course of normal brain development as a basis for understanding atypical brain development associated with a variety of developmental, neurological, and neuropsychiatric disorders affecting children and adults. This study enrolled over 500 children, ranging from infancy to young adulthood. The goal was to study each participant at least three times over the course of the project at one of six Pediatric Centers across the United States. Brain MR and clinical/behavioral data have been compiled and analyzed at a Data Coordinating Center and Clinical Coordinating Center. Additionally, MR spectroscopy and DTI data are being analyzed. The study was organized around two objectives corresponding to two age ranges at the time of enrollment, each with its own protocols. * Objective 1 enrolled children ages 4 years, 6 months through 18 years (total N = 433). This sample was recruited across the six Pediatric Study Centers using community based sampling to reflect the demographics of the United States in terms of income, race, and ethnicity. The subjects were studied with both imaging and clinical/behavioral measures at two year intervals for three time points. * Objective 2 enrolled newborns, infants, toddlers, and preschoolers from birth through 4 years, 5 months, who were studied three or more times at two Pediatric Study Centers at intervals ranging from three months for the youngest subjects to one year as the children approach the Objective 1 age range. Both imaging and clinical/behavioral measures were collected at each time point. Participant recruitment used community based sampling that included hospital venues (e.g., maternity wards and nurseries, satellite physician offices, and well-child clinics), community organizations (e.g., day-care centers, schools, and churches), and siblings of children participating in other research at the Pediatric Study Centers. At timepoint 1, of those enrolled, 114 children had T1 scans that passed quality control checks. Staged data release plan: The first data release included structural MR images and clinical/behavioral data from the first assessments, Visit 1, for Objective 1. A second data release included structural MRI and clinical/behavioral data from the second visit for Objective 1. A third data release included structural MRI data for both Objective 1 and 2 and all time points, as well as preliminary spectroscopy data. A fourth data release added cortical thickness, gyrification and cortical surface data. Yet to be released are longitudinally registered anatomic MRI data and diffusion tensor data. A collaborative effort among the participating centers and NIH resulted in age-appropriate MR protocols and clinical/behavioral batteries of instruments. A summary of this protocol is available as a Protocol release document. Details of the project, such as study design, rationale, recruitment, instrument battery, MRI acquisition details, and quality controls can be found in the study protocol. Also available are the MRI procedure manual and Clinical/Behavioral procedure manuals for Objective 1 and Objective 2.young human, child, pediatric, experimental protocol, brain, brain development, development, mri, minc, clinical, behavior, anatomical mri, diffusion tensor imaging, mr spectroscopy, adolescent, clinical data, behavioral data, data visualization software, clinical measure, behavioral measure, physical neurological examination, behavioral rating, neuropsychological testing, structured psychiatric interview, hormonal measure, image collection, neonate, clinical neuroinformatics, dicom, minc2, magnetic resonance, niftiSCR_003394(NIH MRI Study of Normal Brain Development, RRID:SCR_003394)National Institutes of Health Healthy, NormalNICHD, NIDA, NIH Blueprint for Neuroscience Research, NIMH, NINDSrelated to: NIH Data Sharing Repositories, listed by: NITRC, Biositemaps, NIH Data Sharing RepositoriesLast checked downnif-0000-00201http://www.bic.mni.mcgill.ca/nihpd/info/, https://nihpd.crbs.ucsd.edu/nihpd/info/index.html
Beijing: Short TR StudyResource, data set, data or information resourceDataset of resting state fMRI scans obtained using two different TR's in healthy college-aged volunteers. Specifically, for each participant, data is being obtained with a short TR (0.4 seconds) and a long TR (2.0 seconds). In addition this dataset contains a 64-direction DTI scan for every participant. The following data are released for every participant: * 8-minute resting-state fMRI scan (TR = 2 seconds, # repetitions = 240) * 8-minute resting-state fMRI scans (TR = 0.4 seconds, # repetitions = 1200) * MPRAGE anatomical scan, defaced to protect patient confidentiality * 64-direction diffusion tensor imaging scan (2mm isotropic) * Demographic informationnifti, fmri, resting-state fmri, image collection, early adult human, mprage, diffusion tensor imaging, neuroimaging, brain, demographicSCR_003502(Beijing: Short TR Study, RRID:SCR_003502) 1000 Functional Connectomes Project , Beijing Normal University; Beijing; China HealthyNational High Technology Program of China, National Natural Science Foundation of ChinaLast checked downnlx_157642
NephromineResource, data or information resource, databaseA growing database of publicly available renal gene expression profiles, a sophisticated analysis engine, and a powerful web application designed for data mining and visualization of gene expression. It provides unique access to datasets from the Personalized Molecular Nephrology Research Laboratory incorporating clinical data which is often difficult to collect from public sources and mouse data.kidney, gene expression, visualization, clinical, expression profile, gene, mouse model, microarraySCR_003813(Nephromine, RRID:SCR_003813) Life Technologies , University of Michigan; Michigan; USA Kidney disease, Healthy, Lupus nephritis, Chronic kidney disease, Diabetic nephropathylisted by: NIDDK Information NetworkLast checked upnlx_158114
Blueprint EpigenomeResource, protocol, organization portal, portal, consortium, data or information resourceConsortium to further the understanding of how genes are activated or repressed in both healthy and diseased human cells with a focus on distinct types of haematopoietic cells from healthy individuals and on their malignant leukemic counterparts. They will generate at least 100 reference epigenomes and study them to advance and exploit knowledge of the underlying biological processes and mechanisms in health and disease. Reference epigenomes will be generated by state-of-the-art technologies from highly purified cells for a comprehensive set of epigenetic marks in accordance with quality standards set by International Human Epigenome Consortium (IHEC). Access to the data is provided as well as the protocols used to collect the different blood cell types, to perform the different types of epigenomic analyses, etc.). This resource-generating activity will be complemented by hypothesis-driven research into blood-based diseases, including common leukemias and autoimmune disease (Type 1 Diabetes), by discovery and validation of epigenetic markers for diagnostic use and by epigenetic target identification. Since epigenetic changes are reversible, they can be targets for the development of novel and more individualized medical treatments. The involvement of companies will energize epigenomic research in the private sector by the development of smart technologies for better diagnostic tests and by identifying new targets for compounds. Thus the results of the project may lead to targeted diagnostics, new treatments and preventive measures for specific diseases in individual patients, an approach known as "personalized medicine". The Blueprint Data Access Committee will consider applications for access to data sets stored in the European Genome-phenome Archive (EGA) when authorized to do so by the Blueprint consortium and the holders of the original consent documents. Access is conditional upon availability of samples and/or data and signed agreement by the researcher(s) and the responsible employing Institution to abide by policies related to publication, data disposal, ethical approval and confidentiality. At EBI, the ftp site with the data can be found. You can either opt to link to the track hubs yourself or you can add the track hub to a genome browser - UCSC or ENSEMBL. Also Meta Data files and README are available. The data can also be accessed via the BIOMART system.epigenome, hematopoiesis, gene, data set, biomaterial supply resource, antibody, blood cell, blood, cord blood precursor cell, cell, cord blood, bone marrow, rna-seq, dname-seq, dnasei-seq, chip-seq, monocyte, granulocyte neutrophil, eosinophil, macrophage, m0, m1, m2, naive cd4+, naive cd8+, pathwaySCR_003844(Blueprint Epigenome, RRID:SCR_003844)Radboud University; Nijmegen; The Netherlands Healthy, Leukemia, Bood-based disease, Autoimmune disease, Type 1 DiabetesEuropean Union FP7uses: European Genome-phenome Archive, European Bioinformatics Institute, BioMart Project, UCSC Genome Browser, Ensembl, listed by: Consortia-pedia, One Mind Biospecimen Bank ListingLast checked upnlx_158155
WU-Minn HCP 500 Subjects MR and MEG ReleaseResource, data set, data or information resourceBehavioral and 3T MR imaging data from over 500 healthy adult participants with 14 subjects also scanned in resting-state MEG (rMEG) and task MEG (tMEG). Highlights: * Behavioral and demographic data on 550 subjects. * MR imaging data preprocessed using updated pipelines (structural pipeline v3.1, functional pipeline v3.1, diffusion pipeline v3.1, task analysis pipeline v3.3). * Updates to pipelines include a new intersubject registration method called MSMSulc. All MR data from Q1-Q3 releases have been reprocessed. HCP strongly advises against mixing data from this release with previously-released data. * Individual task fMRI grayordinate-based analysis results (available at 2mm, 4mm, 8mm, and 12mm smoothing levels) and volume-based analysis results (4mm smoothing) are available for all complete 500 Subjects tfMRI data, using an updated task analysis pipeline v3.3. * New extensively processed 100- and 400+-subject group-average functional MR data. * Updates to MEG data and access in ConnectomeDB. Structural MRI-based MEG anatomical models and MR data for the 14 MEG1 Release subjects. * Improvements to behavioral data organization and data dictionary, including the addition of previously unreleased restricted behavioral and demographic data. * All imaging data soon to be available on the cloud through Amazon S3. (More information to come!)meg, mri, early adult human, behavioral, demographic, neuroimaging, resting state, task, multimodal, behavioral measure, fmri, imageSCR_003922(WU-Minn HCP 500 Subjects MR and MEG Release, RRID:SCR_003922)WU-Minn Consortium: Human Connectome Project Healthyused by: NIF Data FederationLast checked upnlx_158287
HipSciResource, production service resource, biomaterial supply resource, material service resource, data set, service resource, cell repository, material resource, biomaterial manufacture, data or information resourceA UK national induced pluripotent stem (iPS) cell resource that will create and characterize more than 1000 human iPSCs from healthy and diseased tissue for use in cellular genetic studies. Between 2013 and 2016 they aim to generate iPS cells from over 500 healthy individuals and 500 individuals with genetic disease. They will then use these cells to discover how genomic variation impacts on cellular phenotype and identify new disease mechanisms. Strong links with NHS investigators will ensure that studies on the disease-associated cell lines will be linked to extensive clinical information. Further key features of the project are an open access model of data sharing; engagement of the wider clinical genetics community in selecting patient samples; and provision of dedicated laboratory space for collaborative cell phenotyping and differentiation.stem cell, genomic variation, cellular phenotype, disease mechanism, phenotype, disease, clinical data, clinical, genetics, male, female, cell line, induced pluripotent stem cellSCR_003909(HipSci, RRID:SCR_003909)European Bioinformatics Institute Healthy, Genetic diseaseMRC, Wellcome Trustlisted by: One Mind Biospecimen Bank ListingLast checked upnlx_158252
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