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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

(last updated: Sep 14, 2019)

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Resource NameResource TypeDescriptionKeywordsResource IDProper CitationParent OrganizationRelated ConditionFunding AgencyRelationReferenceWebsite StatusAlternate IDsAlternate URLsOld URLs
KI Biobank - HARMONYResource, disease-related portal, topical portal, research forum portal, biomaterial supply resource, portal, material resource, data or information resourceA twin study characterizing the importance of genetic factors for dementia and using discordant twin pairs to study other putative risk factors which control for genetic propensity to develop the disease. Molecular genetic studies have identified a number of mutations and other markers associated with early age of onset Alzheimer''''s disease. However, most cases of late age of onset dementia are considered sporadic, that is, without a clear genetic basis. Twin studies provide a unique opportunity to characterize the importance of genetic factors for dementia. Discordant twin pairs additionally provide the opportunity to study other putative risk factors which controlling for genetic propensity to develop the disease. In the first wave of the Study of Dementia in Swedish Twins, all SATSA twins born before 1935 have been screened for dementia symptoms. Over 190 suspects have been identified. This pilot study has been expanded to the entire registry in the study known as HARMONY. All twins aged 65 and older were invited to participate in a computer assisted telephone screening interview. A total of 13,519 individuals completed the interview (response rate = 75.9%). Dementia screening was based on the TELE, which includes the 10-item MSQ, other cognitive items (counting backwards, recalling three words, and similarities), and questions about health and daily functioning; or on Blessed scores obtained from a proxy interview. Among those screened, 1565 were positive for suspicion of dementia and were referred for complete clinical evaluation by a physician and a nurse. Once the preliminary in-person evaluation suggested that the suspected case was demented, the twin partner was also invited for an identical clinical work-up. Response rate for clinical evaluations is 71.4%. Approximately half of those visited for evaluation have been diagnosed as demented according to DSM-IV criteria, of which two-thirds have Alzheimer''''s disease. An extensive assessment of probable risk exposure is also included. Longitudinal follow-up is yet another feature of the study. Association studies with candidate genes are also being performed. Types of samples * DNA Number of sample donors * 1154 (sample collection completed)interview, late adult human, clinical evaluation, association study, candidate gene, gene, risk factor, twin, longitudinalSCR_008884(KI Biobank - HARMONY, RRID:SCR_008884)Karolisnka Biobank Dementia, Alzheimer''''s disease, Discordant twin, AgingNIHrelated to: Swedish Twin Registry, KI Biobank - SATSA, listed by: One Mind Biospecimen Bank ListingLast checked downnlx_151298
BrainNet Europe Sampling ProtocolsResource, protocolSampling protocols produced by the BrainNet Europe Consortium generally with five types of dissection and brain processing procedures defined in all disease related protocols. * Fresh brain dissection * Fresh brain processing * Dissection of formalin-fixed brain * Histology and immunohistochemistry * Processing fresh braindna preservation, rna preservation, protein preservation, macrodissection, microdissection, tissue sampling, brain banking, dissection, brain processing, brain, fresh, formalin-fixed, histology, immunohistochemistrySCR_000484(BrainNet Europe Sampling Protocols, RRID:SCR_000484)BrainNet Europe Dementia, Depressive Disorder, Schizophrenia, Motor Neuron Disease, Neurodegenerative diseaseLast checked downnlx_158157
Alzheimer Society of CanadaResource, regional funding resource, portal, funding resource, data or information resourceA nonprofit health organization that works to improve the quality of life of Canadians affected by Alzheimer's disease and other dementias. This organization also supports research on the cause and potential cures for the disease through education and funding.dementia, alzheimer's, disease, research, funding, nonprofit, canadaSCR_000485(Alzheimer Society of Canada, RRID:SCR_000485)Alzheimer's disease, DementiaLast checked downnlx_158162
VISAGES ResearchResource, topical portal, portal, organization portal, data or information resourceResearch team focused on research and development of new algorithms in medical imaging, information processing and computer assisted intervention in the context of the pathologies of the central nervous system. Research team jointly affiliated to INSERM (National Institute of Health and Scientific Research), Inria (National Institute of Research in Computer Sciences and Automation) and IRISA / UMR CNRS 6074, University of Rennes I. Multidisciplinary team merging researchers in image processing and medical, image, processing, researcher, medical, doctor, development, algorithm, information, pathology, central, nervous, systemSCR_000749(VISAGES Research, RRID:SCR_000749)University of Rennes 1; Rennes; France Multiple Sclerosis, Epilepsy, Parkinson, Dementia, Stroke, Depression, Schizophreniarelated to: EmpennLast checked downnif-0000-10223
Abbreviated Mental Test ScoreResource, material resource, assessment test providerA 10 question assessment to assess elderly patients for the possibility of dementia. The test has utility across a range of acute and outpatient settings. It takes five minutes to administer and must include all 10 questions. A score of less than 7 or 8 suggests cognitive impairment. Scoring: * 7-10 (correct) No Cognitive Impairment * 6-0 (correct) Cognitive Impairmentlate adult human, memory, memory loss, confusionSCR_003677(Abbreviated Mental Test Score, RRID:SCR_003677)Curtin University; Western Australia; Australia Dementia, Cognitive impairmentReferences (2)Last checked downnlx_157830
Mini-Mental State ExaminationResource, material resource, assessment test providerA 30 question assessment test to screen patients for cognitive impairment that is commonly used in medicine to screen for dementia. It is also used to estimate the severity of cognitive impairment and to follow the course of cognitive changes in an individual over time, thus making it an effective way to document an individual's response to treatment. It takes about 10 minutes and examines functions including arithmetic, memory and orientation.questionnaire, late adult human, memory, cognition, arithmetic, orientationSCR_003681(Mini-Mental State Examination, RRID:SCR_003681)Cognitive impairment, Dementiarelated to: Standardized Mini-Mental State ExaminationLast checked downnlx_157834
Hungarian Neurological-Psychiatric BiobankResource, biomaterial supply resource, material resource, tissue bank, data or information resourceThe Hungarian Society of Clinical Neurgenetics established a nationwide collaboration for prospective collection of human biological materials and databases from patient with neurological and psychiatric diseases. The basic triangle of the NEPSYBANK is the sample, the information and the study management. The present participants of the NEPSYBANK are the Department of Neurology and Psychiatry of the four Medical Universities (in Budapest, Debrecen, Pecs, Szeged) and the National Institute of Psychiatry and Neurology in Budapest. The NEPSYBANK is a disease based biobank collecting both phenotypical and environmental data and biological materials such as DNA/RNA, whole blood, plasma, cerebral spinal fluid, muscle / nerve / skin biopsy, brain, and fibroblast. The target of the diseases is presently (Phase I): stroke syndromes, dementias, movement disorders, motoneuron diseases, epilepsy, multiple sclerosis, schizophrenia, alcohol addiction. In the near future (Phase II.) it is planned to enlarge the scale with headaches, disorders of the peripheral nerves, disorders of neuromuscular transmission, disorders of skeletal muscle, depression, anxiety. DNA/RNA is usually extracted from whole blood, but occasionally different tissues such as muscle, brain etc. can be used as well. The extracting procedures differ among the institutes, but in all cases the concentration and the quality of the DNA/RNA must be registered in the database. Participating institutional biobanks have committed themselves to follow common quality standards, which provide access to samples after prioritization on scientific grounds only. In every case the following data are registered. 1. General data: main bank categories, age, sex, ethnicity, body height, body weight, economic stats, education, type of place of living, marital status, birth complications, alcohol, drugs, smoking. 2. Sample properties (sample ID, type of sample, date of extraction, concentration, and level of purity). General patient data as blood pressure, heart rate, internal medical status, ECG, additional diseases. Disease specific question e.g. in schizophrenia the diagnosis after DSMIV and ICD 10, detailed diagnostic questions after both classification, detailed psychiatric and neurological status, laboratory findings, rating scales, data of neuroimaging, genetic tests, applied medication (with generic name, dose, duration), adverse drug effects and other treatments. The Biobank Information Management System (BIMS) is responsible for linkage of databases containing information on the individual sample donors. If you want to have samples from the NEPSYBANK an application must be submitted containing the following information: short research plan including aims and study design, ethic application with a positive decision, specific demands regarding the right of disposition, agreements with grant organizations which regulate immaterial property, information about financing (academic grants, support from industry). All participants have the right to withdraw their samples through a simple order.neurology, psychiatry, genomic, gene, genetic, disease, phenotype, clinical data, environment, dna, rna, whole blood, plasma, cerebral spinal fluid, muscle, biopsy, nerve, skin, brain, fibroblast, tissue, blood, frozen, liquid nitrogen, neurological disease, psychiatric disease, stroke, dementia, movement disorder, motor neuron disease, epilepsy, multiple sclerosis, schizophrenia, alcohol, addiction, alcohol addiction, headache, peripheral nerve disorder, neuromuscular transmission disorder, skeletal muscle disorder, depressive disorder, anxietySCR_003715(Hungarian Neurological-Psychiatric Biobank, RRID:SCR_003715)Neurological disease, Psychiatric disease, Stroke, Dementia, Movement disorder, Motor Neuron Disease, Epilepsy, Multiple Sclerosis, Schizophrenia, Alcohol addiction, Headache, Peripheral nerve disorder, Neuromuscular transmission disorder, Skeletal muscle disorder, Depressive Disorder, Anxietylisted by: One Mind Biospecimen Bank ListingPMID:17448454Last checked downnlx_13478
Greek Association of Alzheimers Disease and Related DisordersResource, disease-related portal, topical portal, portal, data or information resourceA non-profit organization whose aim is to offer advice concerning the care of Alzheimer''''s disease patients, information and services for the people affected and their families. Also, to offer mutual help to the family members of the patients in order to reduce the social, economic and emotional cost deriving from the long care of people suffering from dementia. Lastly, the association attempts to publicize the social needs of the population affected and to inform the public in order to be acquainted with the problem. The mission of the Greek Association of Alzheimer''''s Disease is * the early diagnosis of dementia by scientists * the promotion of research * education and training for all the stakeholders * the development of Care Units for patients with Alzheimer''''s Disease * the provision of useful information and advise (24 hour help-line) on dementia problems (caring, legal or financial issues) * the presentation of lectures by health professionals and informal carers, covering all aspects of Alzheimer Disease * and the development of professional seminars during the whole year.late adult humanSCR_003938(Greek Association of Alzheimers Disease and Related Disorders, RRID:SCR_003938)Alzheimer's disease, Dementia, Agingrelated to: Alzheimer Europe, PharmaCog, Alzheimers Disease InternationalLast checked downnlx_158314
Penn Alzheimer's Disease CenterResource, disease-related portal, topical portal, portal, data or information resourceA national Alzhiemer's disease research center funded by the National Institute on Aging, and the research arm of the Penn Memory Center.alzheimer's disease, memory, dementia, late adult human, disease related portalSCR_004444(Penn Alzheimer's Disease Center, RRID:SCR_004444)University of Pennsylvania Center for Neurodegenerative Disease Research Alzheimer's disease, Dementia, AgingNational Institute on AgingLast checked downnlx_144494
Florida Alzheimer's Disease Research CenterResource, disease-related portal, topical portal, portal, data or information resourceA statewide consortium dedicated to Alzheimer's disease research to better understand the disease and related memory disorders. It includes Alzheimer's researchers and clinicians from institutions across Florida such as USF Health, Mayo Clinic Jacksonville, and Mount Sinai Medical Center. The purpose of the ADRC is to assist institutions in developing an infrastructure (cores) that can be used for various research projects with the goal of better understanding Alzheimer's disease and related disorders. The Florida ADRC is comprised of six cores, three projects and three pilot projects among other collaborations that utilize these cores.disease related portal, alzheimer's disease, memory disorder, dementia, clinical, late adult humanSCR_004940(Florida Alzheimer's Disease Research Center, RRID:SCR_004940)University of South Florida; Florida; USA Alzheimer's disease, Memory disorder, Dementia, Mild cognitive impairmentNIArelated to: Alzheimers Disease Genetics ConsortiumLast checked downnlx_143954
NeuroBiobank MunichResource, biomaterial supply resource, brain bank, material resource, tissue bankA brain bank which collects brain tissue from patients who died from various neurological and psychiatric diseases. These tissues are available for biochemical, molecular biological, and other work groups with the aim of supporting research on the pathogenesis, diagnosis, and therapy of these diseases. Collected brains are clinically and neuropathologically well-characterized. The collection and distribution of brain tissue samples is an ongoing process. NeuroBiobank Munich offers help with the organization and implementation of autopsies as well as with the neuropathologic diagnostics. The thematic emphasis of the NeuroBiobank Munich is Parkinson's disease and demential degenerative disorders such as Alzheimer's disease or Creutzfeldt-Jakob disease. NeuroBiobank Munich coordinates the German national brain tissue bank (BrainNet) and the European brain tissue bank (BrainNet Europe).brain, tissue, brain bank, neurological disease, mental disease, parkinson's disease, alzheimer's disease, creutzfeldt-jakob syndrome, post mortem, neurodegenerative disease, dementiaSCR_005014(NeuroBiobank Munich, RRID:SCR_005014)Ludwig-Maximilians-University; Bavaria; Germany Parkinson's disease, Alzheimer's disease, Creutzfeldt-Jakob Syndrome, Neurodegenerative disease, Dementialisted by: One Mind Biospecimen Bank ListingLast checked downnlx_144006
Joseph and Kathleen Bryan Alzheimer's Disease Research CenterResource, disease-related portal, topical portal, research forum portal, patient-support portal, portal, data or information resourceAn Alzheimer's disease center (ADC) that offers support services for families caring for persons with memory disorders, community outreach and education programs, in addition to its clinical and basic research activities. Information on current scientific and clinical findings is offered to the general public, medical and scientific community. An important emphasis of the Bryan ADRC is to advance basic medical discovery concerning AD and related dementias. This basic science mission is facilitated through the DNA cell repository located in the Institute of Genome Sciences and Policy (IGSP) and the Bryan ADRC brain donation program of the Kathleen Price Bryan Brain Bank. These affiliated Bryan ADRC programs provide a source of fresh brain tissue.alzheimer's disease, memory disorder, clinical trial, dementia, human brainSCR_005025(Joseph and Kathleen Bryan Alzheimer's Disease Research Center, RRID:SCR_005025)Duke University School of Medicine; North Carolina; USA Alzheimer's disease, Memory disorder, DementiaNIALast checked downnlx_144012
PheKBResource, software resource, knowledge environment, software repositoryCollaborative environment of building and validating electronic phenotype algorithms using electronic medical records (EMRs) and natural language processing (NLP) for use in genome-wide association studies (GWAS). On this site you can: View existing algorithms, Enter or create new algorithms, Collaborate with others to create or review algorithms, View implementation details for existing algorithms. The Electronic Medical Records and Genomics Network (eMERGE) has investigated whether data captured through routine clinical care using electronic medical records (EMRs) can identify disease phenotypes with sufficient positive and negative predictive values for use in genome-wide association studies (GWAS). Most EMRs captured key information (diagnoses, medications, laboratory tests) used to define phenotypes in a structured format; in addition, natural language processing has also been shown to improve case identification rates. PheKB is an outgrowth of that validation effort. Phenotype algorithms can be viewed by data modalities or methods used: CPT codes, ICD 10 codes, ICD 9 codes, Laboratories, Medications, Vital Signs, Natural Language Processing Algorithms can also be viewed by: * Implementation results (positive predictive value, sensitivity, publications) * Institution * Work Groupphenotype, electronic medical record, medical record, human, clinical, white blood cell, red blood cell, lipid, algorithm, height, cardiac conduction, genome-wide association study, natural language processingSCR_005292(PheKB, RRID:SCR_005292)Vanderbilt University; Tennessee; USA Atrial fibrillation, Crohn''''s disease, Multiple Sclerosis, Rheumatoid arthritis, Type 2 diabetes mellitus, Dementia, Cataracts, Hypothyroidism, Diabetic Retinopathy, High-Density Lipoprotein, Peripheral Arterial Diseaserelated to: eMERGE Network: electronic Medical Records and GenomicsPMID:20362271Last checked downnlx_144339
Comprehensive Neuroscience CenterResource, organization portal, production service resource, analysis service resource, behavioral analysis service, portal, service resource, data or information resourceTHIS RESOURCE IS NO LONGER IN SERVICE, documented on July 08, 2014. A multi-disciplinary institute providing specialized diagnostic evaluations, innovative treatments, education and research. It provides a collaborative, team-centered approach to provide innovative diagnostics to assist in developing cutting-edge brain based interventions and treatment strategies to best serve their patient's individual needs. Comprehensive Neuroscience Center is dedicated to working with children and adults who demonstrate neurodevelopmental disorders such as Autism Spectrum Disorders, Attention Deficits Hyperactivity Disorder, Learning Disabilities and Language-based deficits, as well as other neurological-based disorders including Traumatic brain injury, Disorders of Consciousness, Disorders of Aging, Alzheimer's and Dementia.neuroscience, treatment, diagnostics, diagnosis, neurodevelopmental, disorder, autism, hyperactivty, disability, neurological, traumatic brain injury, consciousness, alzheimer's, dementia, adult human, child, interventionSCR_008705(Comprehensive Neuroscience Center, RRID:SCR_008705)Neurodevelopmental disorder, Autism Spectrum Disorder, Attention deficit-hyperactivity disorder, Learning Disability, Language-based deficit, Neurological-based disorder, Traumatic brain injury, Disorder of Consciousness, Disorder of Aging, Alzheimer's disease, DementiaLast checked downnif-0000-37854
NIMH Brain Tissue CollectionResource, biomaterial supply resource, biospecimen repository, tissue bank, service resource, brain bank, storage service resource, material resource, material storage repositoryA collection of brain tissue from individuals suffering from schizophrenia, bipolar disorder, depression, anxiety disorders, and substance abuse, as well as healthy individuals. The research mission of the NIMH Brain Bank is to better understand the underlying biological mechanisms and pathways that contribute to schizophrenia and other neuropsychiatric disorders, as well as to study normal human brain development.schizophrenia, bipolar disorder, depressive disorder, anxiety disorder, substance abuse, healthy, neurological disorder, mental disease, suicide, tourette's syndrome, dementia, brain development, brain, brain tissue, tissue, post-mortem, normal control, Identifier: NCT00001260SCR_008726(NIMH Brain Tissue Collection, RRID:SCR_008726)NIMH Intramural Research Program Clinical Brain Disorders Branch Schizophrenia, Bipolar Disorder, Depressiive Disorder, Anxiety Disorder, Drug Abuse, Healthy, Neurological disorder, Mental disease, Suicide, Tourette's Syndrome, Dementia, Normal control, AgingNIMHlisted by: One Mind Biospecimen Bank ListingLast checked downnlx_143684
University of Kentucky Alzheimer's Disease CenterResource, disease-related portal, topical portal, portal, data or information resourceAlzheimer's Disease Center that serves as the focal point for all Alzheimer's disease-related activities at the University of Kentucky and the Commonwealth of Kentucky providing an environment and core resources that catalyze innovative research, outreach, education, and clinical programs. Their ADC plans to build on its historic strengths and capitalize on emerging opportunities to provide an infrastructure that supports research designed to translate knowledge into therapeutic strategies for AD. They focus on two interrelated themes: Transitions and Translation. Their overall emphasis is to more effectively bridge the gap between basic research and clinical studies by facilitating translational efforts. They also carefully characterize transitions across the spectrum of cognitive impairment (normal/ preclinical AD/ MCI/ dementia), with focus on definition of early disease, and continue to support neuropathology as the bedrock of our center. The Alzheimer Disease Center's 2006-2011 grant award from the National Institute on Aging consists of five cores: * Administrative Core * Clinical Core * Biostatistics and Data Management Core * Neuropathology Core * Education & Information Transfer Corelate adult human, brain, memory, clinic, alzheimerSCR_008767(University of Kentucky Alzheimer's Disease Center, RRID:SCR_008767) University of Kentucky; Kentucky; USA , Sanders Brown Center on Aging Cognitive impairment, Alzheimer's disease, Aging, Mild cognitive impairment, DementiaNIALast checked downnlx_144058
Michigan Alzheimer's Disease Center Brain BankResource, biomaterial supply resource, biospecimen repository, tissue bank, service resource, brain bank, storage service resource, data or information resource, material resource, material storage repositoryAn organization that provides scientists with human tissue from Alzheimer's patients and patients with related brain disorders. Brain tissue is collected from research studies at the University of Michigan, as well as other research centers, and are donated by the families of the patients or the participants themselves. Tissues that are present in the Brain Bank are pre-characterized by pathologists and can be provided to researchers upon request.alzheimer's disease, dementia, late adult human, brain, tissue, brain tissue, autopsy, brain donation, clinical dataSCR_008774(Michigan Alzheimer's Disease Center Brain Bank, RRID:SCR_008774)Michigan Alzheimer's Disease Center Alzheimer's disease, Dementia, Aginglisted by: One Mind Biospecimen Bank ListingLast checked downnlx_144107
University of Pennslyvania Brain BankResource, biomaterial supply resource, biospecimen repository, tissue bank, service resource, brain bank, storage service resource, material resource, material storage repositoryA brain and tissue bank that contains human brain samples from patients with Alzheimer's disease (AD), Parkinson's disease (PD) and other related neurodegenerative dementias and movement disorders. This brain bank serves as a resource for scientists and researchers, providing access to tissue samples for further research. While priority is given to University of Pennsylvania researchers, this bank will provide requests to researchers not associated with the University of Pennsylvania. This tissue bank accepts donations from those seeing a University of Pennsylvania physician or collaborator.nervous system tissue, brain tissue, spinal cord, brain, tissue, dna, rna, slide, paraffin, alzheimer's disease, parkinson's disease, amyotrophic lateral sclerosis, frontotemporal disease, aging related neurodegenerative disorder, mild cognitive impairment, dementia, late adult human, clinical data, neurodegenerative diseaseSCR_008820(University of Pennslyvania Brain Bank, RRID:SCR_008820) Penn Alzheimer's Disease Center , University of Pennsylvania Center for Neurodegenerative Disease Research Alzheimer's disease, Parkinson's disease, Amyotrophic Lateral Sclerosis, Frontetemporal disease, Aging related neurodegenerative disorder, Mild Cognitive Impairment, Dementia, AgingNIHlisted by: One Mind Biospecimen Bank ListingLast checked downnlx_144493
MUSC Center on Aging Campbell Neuropathology LaboratoryResource, biomaterial supply resource, biospecimen repository, tissue bank, service resource, brain bank, storage service resource, material resource, material storage repositoryA brain bank and biospecimen repository that provides research materials to clinicians, scientists and pathologists in South Carolina. The bank provides both control and diseased biospecimens and brain tissue needed for research in Alzheimer's disease, Parkinson's disease and other related neurological disorders. The Campbell Laboratory coordinates the brain tissue donation program, provides post-mortem confirmation of a patient having neurological disorders, and leads research trials. Any South Carolina resident can choose to sign up as a tissue donor and have their brain tissue donated post-mortem to be used for neurological disorder research. The tissue bank will process and analyze these tissue samples and send the results to the deceased person's family.brain tissue, brain, tissue, alzheimer's disease, parkinson's disease, neurological disorder, stroke, dementia, normal control, late adult human, clinical trialSCR_008826(MUSC Center on Aging Campbell Neuropathology Laboratory, RRID:SCR_008826)Medical University of South Carolina Center on Aging Alzheimer's disease, Parkinson's disease, Neurological disorder, Stroke, Aging, Dementialisted by: One Mind Biospecimen Bank ListingLast checked downnlx_144505
Washington University Knight Alzheimers Disease Research CenterResource, disease-related portal, topical portal, bibliography, assessment test provider, brain bank, training resource, biomaterial supply resource, tissue bank, narrative resource, service resource, portal, storage service resource, training material, material storage repository, material resource, postdoctoral program resource, data or information resourceResearch center which facilitates advanced research on the clinical, genetic, neuropathological, neuroanatomical, biomedical, psychosocial, and neuropsychological aspects of Alzheimer's disease, as well as other related brain disorders. This center is supported by the National Institute on Aging and, more specifically, is a research arm of the Memory and Aging Project.genetic, alzheimers disease, biomedical, brain, clinical, cure, dementia, development, disease, neuroanatomical, neurodegenerative disease, neuropathological, neuropsychological, research, senile, treatment, agingSCR_000210(Washington University Knight Alzheimers Disease Research Center, RRID:SCR_000210)Washington University in St. Louis; Missouri; USA Alzheimer's disease, Dementia, AgingNIALast checked upnif-0000-11285, nlx_144153, SCR_008779
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