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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

(last updated: Sep 3, 2019)

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2,403 Results - per page

Resource NameResource TypeDescriptionKeywordsResource IDProper CitationParent OrganizationRelated ConditionFunding AgencyRelationReferenceWebsite StatusAlternate IDsAlternate URLsOld URLs
Tata Memorial Hospital Tissue BankResource, biomaterial supply resource, material resource, tissue bankNot yet vetted by NIF curatorSCR_010633(Tata Memorial Hospital Tissue Bank, RRID:SCR_010633)Last checked downnlx_66170https://tmc.gov.in/actrec/index.php/
Australian Prostate Cancer Tissue BankResource, biomaterial supply resource, material resource, tissue bankNot yet vetted by NIF curatorSCR_013221(Australian Prostate Cancer Tissue Bank, RRID:SCR_013221)Last checked downnlx_13972
MUW BiobankResource, biomaterial supply resource, material resource, tissue bankNot yet vetted by NIF curatorSCR_010632(MUW Biobank, RRID:SCR_010632)Last checked downnlx_60522
Singapore Tissue NetworkResource, biomaterial supply resource, material resource, tissue bankTHIS RESOURCE IS NO LONGER IN SERVICE, documented August 22, 2016.SCR_010697(Singapore Tissue Network, RRID:SCR_010697)Last checked downnlx_81651http://www.stn.org.sg/
Astellas Pharma Inc.Resource, portal, organization portal, commercial organization, data or information resourceA Japanese pharmaceutical company formed from the merger of Yamanouchi Pharmaceutical Co., Ltd. and Fujisawa Pharmaceutical Co., Ltd. Astellas' franchise areas are urology, immunology (transplantation), dermatology, cardiology, and infectious disease. Priority areas for R&D are infectious diseases, diabetes, gastrointestinal diseases, oncology, and diseases of the central nervous system. The company's headquarters are in Tokyo, with research centers in Tsukuba and Osaka. Clinical development is centered in Northbrook, Illinois and Leiderdorp, Netherlands. Combined revenues of the two pre-merger companies were $7.9 billion in 2004. Worldwide the company employs about 17,000 people. (Wikipedia)pharmaceutical, drugSCR_003769(Astellas Pharma Inc., RRID:SCR_003769)Last checked downnlx_158074
DUPCheckResource, service resource, people resourceA web-based tool to screen for duplicate patients in clinical trials within and across studies, sponsors and therapeutic areas.clinical trialSCR_003875(DUPCheck, RRID:SCR_003875)NEWMEDS Last checked downnlx_158200
Phelan-McDermid Syndrome International RegistryResource, people resource, patient registryInternational registry that consolidates information from individuals with Phelan-McDermid Syndrome into a single database, which will be utilized by researchers to understand Phelan-McDermid Syndrome better. In order to accelerate translational efforts (moving from basic laboratory research to meaningful health outcomes, such as therapies and treatments) related to Phelan-McDermid Syndrome, PMSF is funding the Phelan-McDermid Syndrome International Registry. The Registry is important for characterizing and understanding the syndrome better. Not only will the Registry provide valuable information for families and doctors to make the best care decisions possible, it will be important to help researchers decide what are the most important challenges to address. The Registry will also help scientists find out if there are any PMS patients who might be a good match for their research studies. Collecting information from PMS patients is very important, but protecting the privacy of people affected by PMS is also extremely important. In order to protect your privacy, Patient Crossroads (the company that designed the registry software) has designed many safeguards. Your child''s information will be de-identified so no one who looks at the data can identify you or your child. Your child''s information will be assigned a code. If a researcher is interested in learning more about your child, the researcher will ask the Patient Crossroads/PMSIR genetic counselor to contact you. A scientist will not be able to receive any identifying information about your child unless you give explicit consent for your child''s identity to be released to that researcher. BE PART OF OUR INTERNATIONAL REGISTRY The Registry will provide valuable information for families and doctors to make the best care decisions possible, and it will help researchers decide what are the most important challenges to address in PMS. Establishing the registry addresses two important scientific needs. First, scientists studying PMS need accurate, firsthand information to understand how PMS affects people. Second, scientists who are ready to start studies, such as those that test new treatments, will be able to access The Registry to identify people that may be eligible to participate in studies. In either case, your privacy is assured while the cause of research is advanced. While raw data about PMS will be available to scientists, they won''t have access to any identifying information about your child unless you agree to have your child''s identity released.phelan-mcdermid syndrome, clinical trial, registry, therapy, treatment, childSCR_004230(Phelan-McDermid Syndrome International Registry, RRID:SCR_004230)Phelan-McDermid Syndrome Foundation Phelan-McDermid SyndromePhelan-McDermid Syndrome FoundationLast checked downnlx_143654
Duke Biospecimen RepositoryResource, biomaterial supply resource, material resource, tissue bankThe Duke Institute for Genome Sciences & Policy (IGSP), in partnership with the Duke University School of Medicine Research Foundation and Department of Pathology (SOMRF), has established the Duke IGSP Biospecimen Repository as a centralized and accessible biological resource for Duke Investigators and research programs. The Repository is a standardized, regulatory-compliant and privacy protected repository for fluid and tissue biospecimens, and enables Duke investigators to reduce costs, and eliminate redundancies and significant risks associated with alternative biobanking practices, while facilitating integration of clinical trials and translational research programs with molecular profiling technologies. In order to ensure sample and data integrity and comparability, the Biorepository is developing, evaluating, and implementing evidence-based biobanking ''best practices''. Centralization of activities to a dedicated and expert staff and facility allows small and large research programs to reduce costs through elimination of redundancies and achieving efficiencies and economies of scale. The Duke-IGSP Biorepository is committed to ensuring appropriate consent, approved use, and protection of privacy through compliance with HIPAA regulations and IRB guidelines. The Duke-IGSP Biospecimen Repository will facilitate the integration of clinical research programs with molecular profiling technologies, enabling large-scale ''omic'' research programs that will inform and drive the development of new generations of targeted diagnostics, therapies, and preventions, which in turn will transform clinical outcomes.fluid, tissueSCR_004306(Duke Biospecimen Repository, RRID:SCR_004306)Duke University; North Carolina; USA listed by: One Mind Biospecimen Bank ListingLast checked downnlx_32022http://www.genome.duke.edu/cores/biorepository/
UTHealth BioBankResource, biomaterial supply resource, service resource, storage service resource, material storage repository, material resource, data or information resourceThe University of Texas Health Science Center at Houston (UTHealth) Clinical and Translational Sciences (CCTS) BioBank employs a federated rather than a centralized model which encourages participation by sample owners who are concerned about guaranteeing their ownership of samples and sample information about patients, samples and related clinical data. In a federated model, individual sites agree on shared policies and procedures for data and sample sharing and oversight. Samples remain with and are governed by the contributing principal investigator at each site. The contributing investigator has final authority whether or not to collaborate or to release samples to qualified researchers. The goal of SLED (Sample Location and Enhanced Distribution) is to help researchers overcome two of the biggest obstacles preventing their research from beginning: 1) location of samples and related data, and 2) requesting of samples and related data. Prior to SLED''s inception the existing system was limited to providing links to samples and data and relying on phone calls to sample owners to facilitate sharing. Collaboration between the CTSA Biobank Consortium and the informatics team at the University of Texas School of Biomedical Informatics is ongoing during this effort. The initial design was constructed using best practices offered by NIH, NCI, and other biobank industry leaders to support and to improve synergy and interaction among various research efforts. Through SLED, researchers will be able to search for samples using a variety of criteria including availability, clinical data, consent criteria, patient demographics, patient diagnoses, study data, and sample type at local and national biobank sites.clinical dataSCR_004570(UTHealth BioBank, RRID:SCR_004570)University of Texas Health Science Center at Houston; Texas; USA Alllisted by: One Mind Biospecimen Bank ListingLast checked downnlx_62871
Fox Chase Biosample Repository Core FacilityResource, biomaterial supply resource, data or information resource, material resource, tissue bank, cell repositoryFox Chase has developed a facility dedicated to the collection and distribution of human subject biosamples and supporting personal and family cancer history data. In response to announcement (CA-00-025; P30 CA06927S2), the Fox Chase Cancer Center''s Biosample Repository (BR) and Tumor Bank Facility (TBF) is making blood specimens (i.e., whole blood, plasma, platelet-rich plasma, platelet homogenates, red blood cells, leukocytes, lymphoblastoid cell lines, and DNA isolated from leukocytes) and tumor tissues (i.e., multi-tissue microarrays and tumor DNAs) collected by our facilities available for research. Request for blood and tissue will be reviewed by a panel of scientists and ranked. Priority will be given to those investigators with current NIGH/NCI funding, but will be made available as recommended by the internal and external advisory committees. * Blood Inventory: Plasma, Serum, Whole Blood, Lymphocytes, DNA * Tissue Inventory: Tumor and Normal Adjacent Tissue, Fresh-Frozen, Formalin-Fixed Paraffin-Embedded Tissue, OCT Embedded Tissue, Ethanol-fixed Tissueblood, whole blood, serum, lymphocyte, plasma, platelet-rich plasma, platelet homogenates, red blood cell, leukocyte, lymphoblastoid cell line, dna, tumor tissue, normal adjacent tissue, multi-tissue microarray, tumor dna, fresh-frozen, formalin-fixed paraffin-embedded, oct embedded, ethanol-fixed, cancer, control, tumorSCR_004746(Fox Chase Biosample Repository Core Facility, RRID:SCR_004746)Fox Chase Cancer Center Cancer, Controllisted by: One Mind Biospecimen Bank ListingLast checked downnlx_75230
da Vinci European BiobankResource, biomaterial supply resource, material resource, data or information resourceBioBank that collects, stores, processes and distributes biospecimens and the associated data. The biospecimens are human and non-human genetic materials, proteins, cells, tissues and biofluids. The data are the biological information associated to the samples and, in the case of human samples, the clinical information pertaining to the donor. The da Vinci European BioBank (daVEB) is a multicenter biobank with a centralized IT infrastructure and a main repository located at the Polo Scientifico (Scientific Campus of the University of Florence) in Sesto Fiorentino (Florence, Italy). Hosted by the Magnetic Resonance Center (CERM), an expert center on protein structure and metabolomics, daVEB's aim is to host as rich as possible biological human sample collections, stored accordingly to EU guidelines, in order to offer a powerful tool in the study of complex diseases. At the end of July 2011, the da Vinci European BioBank of the Pharmacogenomics FiorGen Onlus Foundation has been audited and got the quality certification according to UNI EN ISO 9001:2008 for Collection, storage and distribution of biological samples and the associated data for scientific research. Besides the samples stored at da Vinci European BioBank in Sesto Fiorentino (Florence), the daVEB is also the administrative biobank for research sample collections that are stored in the delocalized repositories. All the sample collections must be registered in the biobank: * sample collections taken within the regular health care * samples taken from healthy individuals or other persons out of the regular health care * samples that have been taken in hospitals within research protocols on specific pathologies all transferred to daVEB endowed with a transfer agreement signed by the donor. The Research Units actually afferent to daVEB are delocalized in the Florence, Prato, Pisa and Siena provinces. Delocalized repositories are under construction in Tuscany.clinical data, metabolomics via 1h-nmr, complex diseaseSCR_004908(da Vinci European Biobank, RRID:SCR_004908)University of Florence; Florence; Italy Normal, Disease, Healthylisted by: One Mind Biospecimen Bank ListingLast checked downnlx_87590
ADHD-200 SampleResource, disease-related portal, data set, topical portal, portal, data or information resourceA grassroots initiative dedicated to accelerating the scientific community''''s understanding of the neural basis of ADHD through the implementation of open data-sharing and discovery-based science. They believe that a community-wide effort focused on advancing functional and structural imaging examinations of the developing brain will accelerate the rate at which neuroscience can inform clinical practice. The ADHD-200 Global Competition invited participants to develop diagnostic classification tools for ADHD diagnosis based on functional and structural magnetic resonance imaging (MRI) of the brain. Applying their tools, participants provided diagnostic labels for previously unlabeled datasets. The competition assessed diagnostic accuracy of each submission and invited research papers describing novel, neuroscientific ideas related to ADHD diagnosis. Twenty-one international teams, from a mix of disciplines, including statistics, mathematics, and computer science, submitted diagnostic labels, with some trying their hand at imaging analysis and psychiatric diagnosis for the first time. The data for the competition was provided by the ADHD-200 Consortium. Consortium members from institutions around the world provided de-identified, HIPAA compliant imaging datasets from almost 800 children with and without ADHD. A phenotypic file including all of the test set subjects and their diagnostic codes can be downloaded. Winner is presented. The ADHD-200 consortium included: * Brown University, Providence, RI, USA (Brown) * The Kennedy Krieger Institute, Baltimore, MD, USA (KKI) * The Donders Institute, Nijmegen, The Netherlands (NeuroImage) * New York University Medical Center, New York, NY, USA (NYU) * Oregon Health and Science University, Portland, OR, USA (OHSU) * Peking University, Beijing, P.R.China (Peking 1-3) * The University of Pittsburgh, Pittsburgh, PA, USA (Pittsburgh) * Washington University in St. Louis, St. Louis, MO, USA (WashU)mri, fmri, brain, neuroimaging, attention deficit-hyperactivity disorder, anatomical, resting state functional mri, child, adolescent, human, young, early adult human, functional imaging, structural imaging, normal, normal controlSCR_005358(ADHD-200 Sample, RRID:SCR_005358)1000 Functional Connectomes Project Attention deficit-hyperactivity disorderrelated to: Neuro Bureau, listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)Last checked downnlx_144426
MethylomeDBResource, data or information resource, databaseA database containing genome-wide brain DNA methylation profiles for human and mouse brains. The DNA methylation profiles were generated by Methylation Mapping Analysis by Paired-end Sequencing (Methyl-MAPS) method and analyzed by Methyl-Analyzer software package. The methylation profiles cover over 80% CpG dinucleotides in human and mouse brains in single-CpG resolution. The integrated genome browser (modified from UCSC Genome Browser allows users to browse DNA methylation profiles in specific genomic loci, to search specific methylation patterns, and to compare methylation patterns between individual samples. Two species were included in the Brain Methylome Database: human and mouse. Human postmortem brain samples were obtained from three distinct cortical regions, i.e., dorsal lateral prefrontal cortex (dlPFC), ventral prefrontal cortex (vPFC), and auditory cortex (AC). Human samples were selected from our postmortem brain collection with extensive neuropathological and psychopathological data, as well as brain toxicology reports. The Department of Psychiatry of Columbia University and the New York State Psychiatric Institute have assembled this brain collection, where a validated psychological autopsy method is used to generate Axis I and II DSM IV diagnoses and data are obtained on developmental history, history of psychiatric illness and treatment, and family history for each subject. The mouse sample (strain 129S6/SvEv) DNA was collected from the entire left cerebral hemisphere. The three human brain regions were selected because they have been implicated in the neuropathology of depression and schizophrenia. Within each cortical region, both disease and non-psychiatric samples have been profiled (matching subjects by age and sex in each group). Such careful matching of subjects allows one to perform a wide range of queries with the ability to characterize methylation features in non-psychiatric controls, as well as detect differentially methylated domains or features between disease and non-psychiatric samples. A total of 14 non-psychiatric, 9 schizophrenic, and 6 depression methylation profiles are included in the database.brain, dna methylation, dorsal lateral prefrontal cortex, ventral prefrontal cortex, auditory cortexSCR_005583(MethylomeDB, RRID:SCR_005583)Columbia University; New York; USA NHGRI, NIH, NIMHlisted by: OMICtoolsPMID:22140101Last checked downnlx_146210, OMICS_01843
KI Biobank - NOAKResource, disease-related portal, topical portal, research forum portal, biomaterial supply resource, portal, material resource, data or information resourceTHIS RESOURCE IS NO LONGER IN SERVCE, documented September 2, 2016.nitric oxide, clinical, therapy, lung diseaseSCR_006008(KI Biobank - NOAK, RRID:SCR_006008)Karolisnka Biobank Asthmalisted by: One Mind Biospecimen Bank ListingLast checked downnlx_151389
OligoGenome Resource, data or information resource, resource, databaseThe Stanford Human OligoGenome Project hosts a database of capture oligonucleotides for conducting high-throughput targeted resequencing of the human genome. This set of capture oligonucleotides covers over 92% of the human genome for build 37 / hg19 and over 99% of the coding regions defined by the Consensus Coding Sequence (CCDS). The capture reaction uses a highly multiplexed approach for selectively circularizing and capturing multiple genomic regions using the in-solution method developed in Natsoulis et al, PLoS One 2011. Combined pools of capture oligonucleotides selectively circularize the genomic DNA target, followed by specific PCR amplification of regions of interest using a universal primer pair common to all of the capture oligonucleotides. Unlike multiplexed PCR methods, selective genomic circularization is capable of efficiently amplifying hundreds of genomic regions simultaneously in multiplex without requiring extensive PCR optimization or producing unwanted side reaction products. Benefits of the selective genomic circularization method are the relative robustness of the technique and low costs of synthesizing standard capture oligonucleotide for selecting genomic targets.oligonucleotide, genome, probe, coding region, oligonucleotide sequence, chromosomeSCR_006025( OligoGenome , RRID:SCR_006025)Stanford University; Stanford; California Doris Duke Clinical Foundation, Howard Hughes Medical Foundation, Liu Bie Ju Cha and Family Fellowship in Cancer, NCI, NHGRI, NIDDK, NLM, Reddere Foundation, Wang Family FoundationPMID:22102592Last checked downnlx_151422
PatientCrossroadsResource, patient registry, topical portal, portal, people resource, data or information resourceA trusted third-party gatekeeper of patient data from participants in a rare disease ecosystem, collecting and managing the information in a scalable, cost-effective manner. Each patient registry provides critical disease knowledge which makes that disease easier to study, increasing the probability a treatment can be developed. PatientCrossroads takes a network approach to patient registry programs. Unlike companies that merely sell registry software, we offer a full range of administration, management, and genetic curation services. What does this consolidated, patient-centric approach to patient registries mean? * Patients can more easily find registries and provide their valuable data (including locations of blood and tissue samples as well as reports of diagnoses, disease symptoms, treatment usage, and lifestyle activities) * Patients can be confident in the privacy of their de-identified data and the knowledge that PatientCrossroads does not sell patient data * Researchers and pharmaceutical companies have a larger, more easily accessible pool of potential patients for research studies and clinical trials targeting specific rare diseases * Pharmaceutical companies can collect post-market surveillance data in a more scalable and cost-effective manner * Rare disease advocacy and research foundations can more easily organize their global patient populations for inclusion in trials and studiesdisease, treatment, clinical, patient, registry, drug discovery, clinical trial, research study, genetics, biorepositorySCR_006279(PatientCrossroads, RRID:SCR_006279)Rare diseaseLast checked downnlx_151889
University of Florida DNA and Tissue BankResource, biomaterial supply resource, material resource, tissue bankThe Alpha-1 Foundation DNA and Tissue Bank, established in 2000 by the Alpha-1 Foundation, is a repository specifically for medical information (hyperlink to data points) and tissue samples (DNA, plasma, lung/liver) for alpha-1-antitrypsin deficient individuals, their family and friends. The Bank serves the international scientific community. Currently the Bank has the largest collection of DNA in the world for Alpha-1-antitrypsin research studies. The Alpha-1 Foundation has established a Tissue Bank Advisory Committee which includes a wide representation of physicians, ethicists, attorneys, consumers as well as international experts in tissue banking. Collectively this Advisory Committee reviews requests for research. At this time the Bank has over 2400 members who have provided valuable medical and/or tissue samples. For investigators interested in obtaining tissue samples with phenotypes from the Bank, please contact the Alpha-1 Foundation or our research staff at the University of Florida.SCR_006581(University of Florida DNA and Tissue Bank, RRID:SCR_006581)University of Florida College of Medicine; Florida; USA listed by: One Mind Biospecimen Bank ListingLast checked downnlx_86173http://www.alphaone.ufl.edu/dna_tissue_bank.php
Biobank Ireland TrustResource, biomaterial supply resource, material resource, tissue bank, data or information resourceBiobank Ireland Trust promotes the development of an Irish Hospital Biobank Network to coordinate collection of small samples of cancer and normal tissue and coded patient data from those having a cancer operation. This will facilitate international molecular research collaborations, which may help identify the best treatment for each individual patient - personalized medicine. Biobank Ireland is promoting the development of a Hospital Biobank Network throughout the island of Ireland as a bridge between cancer research and care. This new infrastructure will facilitate large national and international translational research collaborations that will raise Ireland''s research profile and benefit those with cancer. Researchers will have online access to samples and to restricted patient data from participating hospitals and an equitable withdrawal process for scientifically and ethically approved projects. Important research results will be explained to the public. Other Objectives: * To facilitate (inter)national translational research collaborations that may lead to new tests and better, less toxic treatments for those with cancer * To enable molecular research on cancer tissue from clinical trials patients identify the best treatment for each individual patient ????????personalized medicine???????? * Researchers will have online access to samples and restricted patient data from participating hospitals, and a fair release process for scientifically and ethically approved projects * Biobank Ireland recognizes the need to have harmonization in biobanking around the world * Important research results will be explained to the public * Biobank Ireland will seek to have the hospital-based Biobank Network funded by government as standard of caretissue, cancer tissue, normal tissue, blood, clinical data, tumor, frozen, cancer, normalSCR_006430(Biobank Ireland Trust, RRID:SCR_006430)Cancer, Normalbusiness, fundraising events, industry, philanthropistslisted by: One Mind Biospecimen Bank ListingLast checked downnlx_69463http://www.biobankireland.com/index.html
HDBaseResource, disease-related portal, data set, topical portal, portal, data or information resourceA community website for Huntington''s Disease (HD) research that currently contains Y2H and Mass spectrometry protein-protein interaction data centered around the HD protein (huntingtin) and information on therapeutic studies in mouse. Also available are raw Human and Mouse Affymetrix Microarray data. The protein interaction data is from several sources, including interactions curated from the literature by ISB staff, experimentally determined interactions produced by Bob Hughes and colleagues at Prolexys (currently password protected), and interactions reported in a recent publication by Goehler et al from Eric Wanker''s lab. Content areas that may be covered by the site include the following: * Therapeutic studies in mouse, primarily drug screens. * HD mouse models with a focus on timelines of disease progression. * Antibodies used in HD research. * Microarray gene expression studies. * Genes and proteins relevant to HD research. This includes HD itself, the growing list of proteins thought to interact directly or indirectly with huntingtin (Htt), and other genes and proteins implicated in the disease process. * Molecular pathways thought to be involved in the disease process. * Timelines of disease for Mouse modelsdrug, gene expression, huntingtin, mass spectrometry, microarray, protein interaction, protein-protein interaction, y2h, mouse model, treatment, disease, phenotype, brain, striatum, adipose, muscle, gene, protein, antibody, pathwaySCR_007132(HDBase, RRID:SCR_007132)Institute for Systems Biology; Washington; USA Huntington''s disease, ControlHereditary Disease Foundationuses: CytoscapeLast checked downnif-0000-00153
Singapore BiobankResource, biomaterial supply resource, material resource, tissue bankNot yet vetted by NIF curatorSCR_010615(Singapore Biobank, RRID:SCR_010615)Last checked downnlx_53419
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