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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

(last updated: Oct 12, 2019)

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Resource NameResource TypeDescriptionKeywordsResource IDProper CitationParent OrganizationRelated ConditionFunding AgencyRelationReferenceWebsite StatusAlternate IDsAlternate URLsOld URLs
Vietnam Era Twin Registry Biospecimen RepositoryResource, biomaterial supply resource, material resourceThe Vietnam Era Twin (VET) Registry maintains a repository of biological specimens obtained from Registry members. The VET Registry Biospecimen Repository includes DNA, plasma, and serum samples obtained from selected VET Registry members. As the VET Registry is a national resource for studies investigating genetic and non-genetic influences on health and disease in middle age men, this enhances the value of the information collected from VET Registry members to the research community. The VET Registry has developed a general system of protocols for the collection and storage of biological specimens that assures confidentiality for all participants. The biological specimens currently in use are stored at the R&D Core Laboratory at the VA Puget Sound Health Care System (VAPSHCS) in Seattle, WA. The R&D Core Laboratory performs DNA extraction procedures and separates out DNA, plasma, and serum for testing and storage. It is important to note that Core Laboratory staff has absolutely no phenotypic (non-genetic) information about VET Registry members, as the lab is completely blinded to the identity, disease characteristics, and any other research data collected from VET Registry members. The Massachusetts Veterans Epidemiology Research and Information Center (MAVERIC) Core Laboratory is located at the VA Boston Health Care System in Boston, MA, and serves as the long-term storage site for the VET Registry Biospecimen Repository. Before a VET Registry member decides whether to participate in the Biospecimen Repository, the procedures, confidentiality safeguards, and potential risks are explained in great detail. To be able to accommodate the wishes of members, a so-called layered consent process is used which allows members to choose from several options with regard to how their biological specimen will be used in current or future research studies. Such options may include: 1) not having their samples used for any testing beyond the immediate goals of the study; 2) allowing for future testing of their samples restricted to the study for which they provided the sample; or 3) allowing unrestricted future research use of their samples. Members are informed that any future use of their samples would have to be approved by the VET Registry, in addition to an independent ethics committee that protects the rights and welfare of research subjects, this board is more commonly known as an Institutional Review Board or IRB. Confidentiality safeguards include assigning code numbers, as opposed to name or other personal information, on all biological specimens. Zygosity Testing The accuracy of DNA testing makes it the best method for determining zygosity, identical (monozygotic) versus fraternal (non-identical or dizygotic), in VET Registry twin members. The use of DNA for zygosity testing is only performed when both members of a twin pair agree to the testing. Other Genetic Testing for specific genes will not necessarily involve providing the participants with test results.twin, male, adult, dna, plasma, serum, gene, genetic, health, disease, vietnam veteranSCR_008808(Vietnam Era Twin Registry Biospecimen Repository, RRID:SCR_008808)Vietnam Era Twin Registry Vietnam Era Twin Registry member (Vietnam War and Twin), Aginglisted by: One Mind Biospecimen Bank ListingLast checked upnlx_144390
Boston Area Community Health Survey Resource, disease-related portal, topical portal, resource, research forum portal, portal, data or information resourceAn epidemiologic study being conducted in the Boston metropolitan area to examine the prevalence of symptoms for health problems such as interstitial cystitis, urinary incontinence, benign prostatic hyperplasia, prostatitis, hypogonadism, and sexual function. Of interest to the survey are health disparities and inequalities. BACH is especially concerned with lack of adequate health insurance, lack of access to adequate medical care, and how these problems influence patterns of disease. The study also focuses on social determinants of disease that are over and above the contribution of individual characteristics and risk factors. To achieve a randomly sampled population, four neighborhoods were divided into 12 strata and from them investigators selected census blocks. Households were then randomly selected from the census blocks and sampled to identify eligible study participants. Investigators conduct a two-hour, in-home, bilingual field interview of all eligible participants, looking at symptoms and asking questions about lifestyle, physical activity, alcohol use, nutrition, demographics, and morbidity. They also conduct a detailed inventory of medications, both prescribed and over-the-counter, and take two non-fasting blood samples for hormone, cholesterol, and lipid levels that will be stored for future studies. By the time the study ends, approximately 6,000 men and women, ages 30 to 79, from four Boston area neighborhoods that have density levels proportionate with minority populations will have been interviewed in their homes. One third of the randomly sampled population will be African American; one third, Hispanic; and one third, Caucasian.prevalence, symptom, epidemiology, health problem, disparity, inequality, health insurance, medical care, disease, social determinant, risk factor, male, female, adult human, middle adult human, late adult human, interview, african-american, hispanic, caucasian, epidemiological study, lifestyle, physical activity, alcohol use, nutrition, demographics, morbidity, medication, blood, hormone, cholesterol, lipid level, biomaterial supply resourceSCR_007115( Boston Area Community Health Survey , RRID:SCR_007115)NIDDK - National Institute of Diabetes and Digestive and Kidney Diseases Urological problem, Interstitial cystitis, Urinary incontinence, Benign prostatic hyperplasia, Prostatitis, Hypogonadism, Sexual dysfunctionNIDDKrelated to: NIDDK Information Network, listed by: One Mind Biospecimen Bank Listing, submitted by: NIDDK Information NetworkLast checked upnlx_152753
GenomEUtwinResource, disease-related portal, topical portal, database, biomaterial supply resource, research forum portal, portal, material resource, data or information resourceTHIS RESOURCE IS NO LONGER IN SERVICE, documented August 29, 2016. Study of genetic and life-style risk factors associated with common diseases based on analysis of European twins. The population cohorts used in the Genomeutwin study consist of Danish, Finnish, Italian, Dutch, English, Australian and Swedish twins and the MORGAM population cohort. This project will apply and develop new molecular and statistical strategies to analyze unique European twin and other population cohorts to define and characterize the genetic, environmental and life-style components in the background of health problems like obesity, migraine, coronary heart disease and stroke, representing major health care problems worldwide. The participating 8 twin cohorts form a collection of over 0.6 million pairs of twins. Tens of thousands of DNA samples with informed consents for genetic studies of common diseases have already been stored from these population-based twin cohorts. Studies targeted to cardiovascular traits are now being undertaken in MORGAM, a prospective case-cohort study. MORGAM cohorts include approximately 6000 individuals, drawn from population-based cohorts consisting of more than 80 000 participants who have donated DNA samples.genetic, environment, lifestyle, gene, diseaseSCR_002843(GenomEUtwin, RRID:SCR_002843)University of Helsinki; Helsinki; Finland TwinEuropean Unionrelated to: KI Biobank - TwinGene, listed by: One Mind Biospecimen Bank ListingLast checked downnif-0000-25218
KI Biobank - STAGEResource, disease-related portal, topical portal, research forum portal, biomaterial supply resource, data set, portal, material resource, data or information resourceTHIS RESOURCE IS NO LONGER IN SERVCE, documented September 2, 2016. The Swedish twin registry has recently examined all twins in Sweden born between 1959-1985. 25,000 individuals participated in the study. The twins had to implement a Web-based survey on the Internet or a telephone interview where we had to answer questions about, among other things, about the diseases they have, or have had, behaviors, eating and drinking habits, smoking habits, etc. The aim of the study is to extend the information in the Swedish twin registry. Our goal with twin studies are, inter alia, to study the relative importance of the heritage and environment for the emergence of various diseases. The responses from the study is currently the basis for a number of analyses regarding how inheritance and environment affects disease and tobacco habits. Currently third follow-up STAGE where 10,000 twins that had previously taken part are contacted again. The purpose of alteplase randomized controlled trials is to follow up the same individuals one year after the first and second questionnaire replies were received to see if anything has changed. The issues we are interested in the follow-up to include changes in general health, working and living situation, your weight, smoking habits, etc. Study Results The results we have so far come to and which we can present here are figures on the prevalence of certain diseases. The figures give a rough estimate of the incidence of these diseases will look for all individuals, born in Sweden in 1959-1985. The figures are based on the questions on the questionnaire which the twins themselves had to answer whether they have or have had various diseases.adult, gene, environment, survey, interview, disease, behavior, eating habit, drinking habit, questionnaire, nicotine, smoking, nicotine use disorderSCR_006004(KI Biobank - STAGE, RRID:SCR_006004)Karolisnka Biobank Twinrelated to: Swedish Twin Registry, listed by: One Mind Biospecimen Bank ListingLast checked downnlx_151384
BioMarkers for SMA Data PortalResource, data or information resource, databaseA publicly available tool that contains data from the BforSMA clinical study ( ClinicalTrials.gov, NCT00756821 ), a pilot study to identify candidate biomarkers in blood or urine from a wide range of Spinal Muscular Atrophy (SMA) patients that associate with disease severity. It is hoped that the identification of candidate biomarkers will lead to clinical efficacy and longitudinal natural history studies to verify these markers and enable their use as validated pharmacodynamic markers, longitudinal progression markers, or surrogate endpoint measures in clinical trials.sma, biomarker, child, disease, genetic disease, clinical, proteomic, metabolomic, transcriptomic, blood, urineSCR_004920(BioMarkers for SMA Data Portal, RRID:SCR_004920)Neuroscience Information Framework Spinal Muscular AtrophySMA FoundationLast checked downnlx_88529http://neuinfo.org/bforsma http://transmart-dev.neuinfo.org/transmart/search
Project TychoResource, data or information resource, databaseDatabase to advance the availability and use of public health data for science and policy making that includes data from all weekly notifiable disease reports for the United States dating back to 1888. Additional U.S. and international data will be released twice yearly.population, disease, metadata standard, vaccination, public health data, health, incidence rate, death, statisticsSCR_010489(Project Tycho, RRID:SCR_010489)University of Pittsburgh; Pennsylvania; USA Smallpox, Polio, Measles, Mumps, Rubella, Hepatitis A, Whooping cough, Diphtheria, Etc.Bill and Melinda Gates Foundation, NIHReferences (2)Last checked upnlx_157982
Sleep Heart Health StudyResource, disease-related portal, topical portal, portal, data or information resourcePortal for a multi-cohort study focused on sleep-disordered breathing and cardiovascular outcomes implemented by the National Heart Lung and Blood Institute. Recorded signals are: EEG, ECG, EOG, SaO2, HR, EOG, EMG, respiratory inductance plethysmography, respiration (thermistor), position, light.dataset, analysis, sleep, apnea, breathing, disorder, cardiovascular, disease, EEG, ECG, respiration, PSGSCR_016559(Sleep Heart Health Study, RRID:SCR_016559)sleep disorder, sleep apnea, cardiovascular diseaseNHLBIlisted by: National Sleep Research Resource (NSRR), submitted by: Resource Identification PortalPMID:9493915Last checked down
Best Apnea Interventions for Research (BestAIR) sleep studyResource, disease-related portal, topical portal, portal, data or information resourcePortal for sleep study to address challenges in conducting future large-scale trials of sleep apnea treatment. Includes data from sleep apnea patients with cardiovascular disease or risk factors. Signals included in the polysomnography (PSG) montage are ECG, SpO2, airflow, nasal pressure, position, pulse, respiratory effort, snore, tidal volume.data, analysis, sleep, apnea, treatment, cardiovascular, disease, risk, factor, polysomnography, ECG, SpO2SCR_016583(Best Apnea Interventions for Research (BestAIR) sleep study, RRID:SCR_016583)sleep apnea, cardiovascular diseaseNHLBI, Philips Respironics, ResMed Foundationlisted by: National Sleep Research Resource (NSRR)DOI:10.5665/sleep.4266Last checked down
EyeBrowseResource, data set, data or information resourceEyeBrowse displays expressed sequence tag (EST) cDNA clones from eye tissues (derived from NEIBank and other sources) aligned with current versions of the human, rhesus, mouse, rat, dog, cow, chicken, or zebrafish genomes, including reference sequences for known genes. This gives a simplified view of gene expression activity from different parts of the eye across the genome. The data can be interrogated in several ways. Specific gene names can be entered into the search window. Alternatively, regions of the genome can be displayed. For example, entering two STS markers separated by a semicolon (e.g. RH18061;RH80175) allows the display of the entire chromosomal region associated with the mapping of a specific disease locus. ESTs for each tissue can then be displayed to help in the selection of candidate genes. In addition, sequences can be entered into a BLAT search and rapidly aligned on the genome, again showing eye derived ESTs for the same region. EyeBrowse includes a custom track display SAGE data for human eye tissues derived from the EyeSAGE project. The track shows the normalized sum of SAGE tag counts from all published eye-related SAGE datasets centered on the position of each identifiable Unigene cluster. This indicates relative activity of each gene locus in eye. Clicking on the vertical count bar for a particular location will bring up a display listing gene details and linking to specific SAGE counts for each eye SAGE library and comparisons with normalized sums for neural and non-neural tissues. To view or alter settings for the EyeSAGE track on EyeBrowse, click on the vertical gray bar at the left of the display. Other custom tracks display known eye disease genes and mapped intervals for candidate loci for retinal disease, cataract, myopia and cornea disease. These link back to further information at NEIBank. For mouse, there is custom track data for ChIP-on-Chip of RNA-Polymerase-II during photoreceptor maturation.est, expressed sequence tag, eye, gene, genome, cataract, cdna, chicken, clone, cluster, cornea, cornea disease, cow, data, disease, dog, human, locus, maturation, mouse, myopia, photoreceptor, rat, retina, rhesus, rna polymerase-ii, tag, zebrafish, data analysis software, eye tracking deviceSCR_008000(EyeBrowse, RRID:SCR_008000)University of California at Santa Cruz; California; USA Retinal disease, Cataract, Myopia, Cornea diseaseNEIBanklisted by: 3DVCLast checked upnif-0000-07733
Renal Disease PortalResource, disease-related portal, data set, topical portal, portal, data or information resourceAn integrated resource for information on genes, QTLs and strains associated with a variety of kidney and renal system conditions such as Renal Hypertension, Polycystic Kidney Disease and Renal Insufficiency, as well as Kidney Neoplasms.gene, quantitative trait locus, strain, renal hypertension, kidney neoplasm, phenotype, pathway, biological process, disease, kidney, genome, gviewer, chromosome, molecular function, cellular component, visualization, syntenySCR_009030(Renal Disease Portal, RRID:SCR_009030)Rat Genome Database (RGD) Renal disease, Renal hypertension, Polycystic kidney disease, Renal insufficiency, Kidney neoplasm, Diabetes Insipidus, Hyperoxaluria, Renal hypertension, Nephritis, Nephrocalcinosis, Nephrolithiasis, Nephrosis, Renal Fibrosis, Inborn Error of Renal Tubular Transport, Uremiarelated to: NIDDK Information Network, Gene Ontology, submitted by: NIDDK Information NetworkLast checked upnlx_153941
Special Mouse Strains ResourceResource, biomaterial supply resource, material resource, organism supplierResource of special strains of mice that are valuable tools for genetic analysis of complex diseases. They include panels of recombinant inbred (RI) and chromosome substitution (CS) strains.strain panel, frozen, cryopreserved, recombinant inbred mouse, chromosome substitution mouse, consomic strain, gene, disease, strainSCR_002885(Special Mouse Strains Resource, RRID:SCR_002885)Jackson Laboratory Recombinant inbred mouse, Chromosome substitution mouse, Consomic strainNCRR, NIH Office of the Directorrelated to: One Mind Biospecimen Bank Listing, Mouse Phenome Database (MPD), listed by: One Mind Biospecimen Bank ListingLast checked downnif-0000-25593
Biospecimens/Biorepositories: Rare Disease-HUB (RD-HUB)Resource, biomaterial supply resource, data or information resource, material resource, databaseA database of biospecimens collected, stored, and distributed by biorepositories in the United States and around the globe. Its goals are: To help and assist interested parties and investigators search, locate, and identify desired biospecimens needed for their research; to facilitate collaboration and sharing of material and data among investigators across the globe; to accelerate research to facilitate the discovery of new treatments, therapeutics and eventually cures for rare diseases as well as common diseases; to identify, locate and increase the awareness of existing biorepositories across the globe; and to link the RD-HUB with the Global Rare Diseases Patient Registry and Data Repository (GRDR).rare disease, disease, publicSCR_004327(Biospecimens/Biorepositories: Rare Disease-HUB (RD-HUB), RRID:SCR_004327)Office of Rare Diseases Research Rare disease, AgingNIHrelated to: GRDR, listed by: NIH Data Sharing Repositories, One Mind Biospecimen Bank Listing, Accelerated Cure Project MS Repository, Cooperative Human Tissue Network Western Division at Vanderbilt University Medical Center, NIDDK Information Network, lists: NIDDK Central Repository, National Disease Research InterchangeLast checked downnlx_143682http://biospecimens.ordr.info.nih.gov/
PatientCrossroadsResource, patient registry, topical portal, portal, people resource, data or information resourceA trusted third-party gatekeeper of patient data from participants in a rare disease ecosystem, collecting and managing the information in a scalable, cost-effective manner. Each patient registry provides critical disease knowledge which makes that disease easier to study, increasing the probability a treatment can be developed. PatientCrossroads takes a network approach to patient registry programs. Unlike companies that merely sell registry software, we offer a full range of administration, management, and genetic curation services. What does this consolidated, patient-centric approach to patient registries mean? * Patients can more easily find registries and provide their valuable data (including locations of blood and tissue samples as well as reports of diagnoses, disease symptoms, treatment usage, and lifestyle activities) * Patients can be confident in the privacy of their de-identified data and the knowledge that PatientCrossroads does not sell patient data * Researchers and pharmaceutical companies have a larger, more easily accessible pool of potential patients for research studies and clinical trials targeting specific rare diseases * Pharmaceutical companies can collect post-market surveillance data in a more scalable and cost-effective manner * Rare disease advocacy and research foundations can more easily organize their global patient populations for inclusion in trials and studiesdisease, treatment, clinical, patient, registry, drug discovery, clinical trial, research study, genetics, biorepositorySCR_006279(PatientCrossroads, RRID:SCR_006279)Rare diseaseLast checked downnlx_151889
PIDFinderResource, analysis service resource, data analysis service, service resource, production service resourcePIDFinder is a tool for the exploration of the Primary Immunodeficiency Disease Ontology. Apart from browsing the knowledge contained in the ontology, it can also be used for the identification of PIDs based on a set of observed Phenotypes. The PidFinder web application is a developing prototype application that allows non-bioinformaticians to quickly view and use the knowledge contained in the Primary Immunodeficiency Disease Ontology. The application consists of a number of components: * The PIDFinder: allows the selection of a set of phenotypes and subsequently compares the set with the canonical set of phenotypes defined in the PID Ontology. The phenotypes, that can be selected are grouped by biomarker and are thus available in a number of different facets. Once phenotypes have been selected, the application compares them to canonical phenotypes associated with PIDs in the PID Ontology, by computing a semantic similarity measure. The similarity is determined using a Tanimoto Distance - the more closely related an observed phenotype is to a canonical ontology phenotype, the closer the calculated Tanimoto Distance is to 1 - with increasing dissimilarity, the Tanimoto Coefficient tends towards 0. * The Phenotype Explorer: a rudimentary browser for phenotypes currently contained in the PID Ontology. The browser allows the user to find phenotypes based on biomarker categories and provides some basic definitions (not all definitions are available at this stage) and disease association information. * A Heatmap comparing the phenotypic overlap of PIDs: In essence, the heatmap is a many-to-many comparison of the phenotypic overlap between all Primary Immunodeficiency Diseases contained in the PID Ontology. Again, overlap is calculated using a Tanimoto Distance. The heatmap is a matrix, plotting the Tanimoto coefficients for every PID/PID pair. Increased off-diagonal overlap between PIDs most likely indicates genes in the same pathway. * A Phenotype Frequency Visualization: The phenotype frequency visualization is a simple bar chart indicating how often a particular phenotype is associated with a Primary Immunodeficiency Disease in the Ontology. * A PID Expert map: All of the phenotypes and knowledge contained in the Primary Immunodeficiency Disease Ontology has been extracted from primary clinical or research literature. To construct the map, we have extracted the affiliations and locations of the authors of the literature sources and overlayed them on a map. The hope is that this will facilitate the identification of (local) experts on primary immunodeficiency diseases.phenotype, disease, immunodeficiency, biomarker, ontologySCR_005833(PIDFinder, RRID:SCR_005833)Primary Immunodeficiency Diseaserelated to: PIDO - Primary Immunodeficiency Disease OntologyLast checked downnlx_149343
PIDO - Primary Immunodeficiency Disease OntologyResource, ontology, data or information resource, controlled vocabularyThe Primary Immunodeficiency Disease Ontology Project is developing an ontology for the phenotypic description of Primary Immunodeficiency Diseases. The ontology can be used for integrative research in both biomedical and clinical research. Primary Immunodeficiency Diseases (PIDs) are Mendelian diseases, caused by defects or deletions of genes involved in the development, regulation and maintenance of the immune system. They usually affect newborns and toddlers, but can also manifest much later in life. Information about PIDs is often widely scattered across the research literature and a number of databases. PIDO is an attempt to develop both a machine- as well as a human-comprehensible representation of these diseases, starting with a phenotypic descriptions of disease.phenotype, disease, young human, childSCR_005834(PIDO - Primary Immunodeficiency Disease Ontology, RRID:SCR_005834)Google Project Hosting , Hannover Medical School; Lower Saxony; Germany Primary Immunodeficiency DiseaseBBSRC, DFG, European Union FP7, Hannover Medical School; Lower Saxony; Germanyrelated to: PIDFinderPMID:21949270Last checked upnlx_149345
USIDNET: US Immunodeficiency NetworkResource, patient registry, topical portal, portal, people resource, data or information resourceResearch consortium to advance scientific research in the primary immune deficiency diseases (PIDD) and: * Assemble and maintain a registry of patients with primary immunodeficiency diseases to provide a minimum estimate of the prevalence of each disorder in the United States. Provide a comprehensive clinical picture of each disorder and act as a resource for clinical and laboratory research. * Establish a multifaceted mentoring program to introduce new investigators into the field and stimulate interest and research in primary immune deficiency diseases. * Establish an advisory/review committee to maintain a cell/DNA Repository of biologic material from well-characterized PIDD patients for the advancement of scientific research USIDNET operates a large database of patient information for your use. The purpose and scope of this project is to assemble and maintain a registry of residents with primary immunodeficiency diseases. The project was started with the Registry of U.S. Residents with Chronic Granulomatous Disease. Since then, the registry has been expanded and now collects data on all primary immunodeficiency disorders. The following are just a few of the diseases housed in the registry: Chronic Granulomatous Disease, Common Variable Immunodeficiency Disease, DiGeorge Anomaly, Hyper IgM Syndrome, Leukocyte Adhesion Defect, Severe Combined Immunodeficiency Disease, Wiskott-Aldrich Syndrome, X-Linked Agammaglobulinemia Physicians who would like to register their patients or access the registry are encouraged to contact Onika Davis or Lamar Hamilton, USIDNET team, at odavis (at) primaryimmune.org, or lhamilton (at) primaryimmune.orgpatient information, primary immunodeficiency disease, immunodeficiency disease, disease, immune deficiency disease, clinical trail, clinical, primary immune deficiency diseaseSCR_004672(USIDNET: US Immunodeficiency Network, RRID:SCR_004672)Immune Deficiency Foundation Primary immune deficiency disease, Chronic Granulomatous Disease, Common Variable Immunodeficiency Disease, DiGeorge Anomaly, Hyper IgM Syndrome, Leukocyte Adhesion Defect, Severe Combined Immunodeficiency Disease, Wiskott-Aldrich Syndrome, X-Linked AgammaglobulinemiaImmune Deficiency Foundation, NIAID, NIHLast checked upnlx_143859
Kids First Data Resource PortalResource, disease-related portal, topical portal, database, organization portal, service resource, portal, storage service resource, data repository, data or information resourcePortal for analysis and interpretation of pediatric genomic and clinical data to advance personalized medicine for detection, therapy, and management of childhood cancer and structural birth defects. For patients, researchers, and clinicians to create centralized database of well curated clinical and genetic sequence data from patients with childhood cancer or structural birth defects.pediatric, genomic, clinical, disease, data, children, cancer, birth, defect, analysisSCR_016493(Kids First Data Resource Portal, RRID:SCR_016493)pediatric cancer, birth defectNIH, the Common Fund’s Gabriella Miller Kids First Pediatric Research Programrecommended by: National Library of Medicine, BRAIN InitiativeLast checked downSCR_016553https://commonfund.nih.gov/kidsfirst, https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs001168.v1.p1, https://commonfund.nih.gov/kidsfirst
Parkinsons Disease MapResource, disease-related portal, topical portal, data or information resource, portal, databaseKnowledge repository established to describe molecular mechanisms of Parkinson's Disease. It compiles literature-based information on PD into an easy to explore and freely accessible molecular interaction map and offers research-facilitating functionalities such as the overlay of experimental data and the identification of drug targets on the mapparkinson, disease, pd, molecular biology, interaction, drug, targetSCR_016156(Parkinsons Disease Map, RRID:SCR_016156)Parkinsons diseaseLast checked down
DPDx: Laboratory Identification of Parasites of Public Health ConcernResource, topical portal, database, analysis service resource, material analysis service, image collection, data set, service resource, portal, production service resource, storage service resource, biomaterial analysis service, data repository, data or information resourceParasite-related portal including concise reviews of parasites and parasitic diseases, an image library, a review of recommended procedures for collecting, shipping, processing, and examining biologic specimens, and a diagnostic assistance function, in which laboratorians and other health professionals desiring assistance in parasite identification can ask questions and/or send digital images of specimens for expedited review and consultation with DPD staff. This assistance is free of charge. The portal is hoped to strengthen diagnosis of, and enhance the capacity to address the global problem of parasitic diseases, both in the United States and abroad. Potential DPDx applications include: * training and continuing education of laboratorians, using material collected by CDC or contributed by other institutions * provision to health facilities worldwide of diagnostic assistance by CDC staff backed up when needed by experts from other institutions * diagnostic quizzes for self-assessment of laboratorians skills * informal, early detection of unusually clustered, atypical or emerging parasitic diseasesblastocystis, diagnosis, diagnostic, disease, global, gnathostoma, health, life cycle, micrograph, parasite, parasitic disease, pneumocystis, public health, case study, morphology, comparative morphology, intestinal tract, blood-borne parasite, life-cycle, electron micrograph, diagnostic procedureSCR_002335(DPDx: Laboratory Identification of Parasites of Public Health Concern, RRID:SCR_002335)Centers for Disease Control and Prevention Parasitic diseaseLast checked upnif-0000-21126
Geisinger BiobankResource, biomaterial supply resource, material resource, data or information resourceBy collecting and analyzing blood samples from Geisinger''s large patient population, MyCode will help unlock the mysteries of some of the most devastating and debilitating diseases. Blood samples are obtained from patients of certain Geisinger specialty clinics to study specific conditions, such as obesity and cardiovascular disease, and also from patients of Geisinger primary care clinics to provide a representative sample of the regional population. More than 60,000 samples from over 23,000 Geisinger patients have been collected so far, and sample collection is ongoing. MyCode researchers use the blood samples to study the genetic causes of diseases and certain disease-related molecular mediators. Knowledge gained from these studies will allow researchers to pursue innovative approaches to disease prevention, diagnosis and treatment. To be of value for Genomic Medicine research, bio-banked samples must be connected to clinical data: MyCode allows genetic and molecular data about the samples to be connected to medical data in a way that protects patient identity. When a patient agrees to participate in MyCode, blood samples for the MyCode Project are collected during blood draws ordered as part of the patient''s routine medical care. After the sample is drawn and labeled, a staff member from the Weis Center for Research transports the blood to the Geisinger Clinic Genomics Core (GCGC) where it is processed for storage. At this stage, all personal identification markers are removed and the samples are assigned a randomly-selected identification number. A secure key is maintained that allows approved researchers to connect the samples to the clinical data for genomic studies in a way that ensures confidentiality of the information. To maintain confidentiality of MyCode data the code linking the research numbers and the electronic health records are kept in a password-protected files accessible only to MyCode team members. Additionally, all results generated from the samples are reported as a group so that individuals are not identified. The samples are stored indefinitely.gene, genetics, disease, clinical data, genomic medicine, genetic data, molecular data, blood, obesity, cardiovascular disease, other specific conditions, regional populationSCR_005652(Geisinger Biobank, RRID:SCR_005652)Obesity, Cardiovascular disease, Disease, Other conditions, Regional populationBen Franklin Technology Development Authority, Geisinger Clinic Administrative Committee for Researchlisted by: One Mind Biospecimen Bank ListingLast checked downnlx_14718
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