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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

(last updated: Oct 12, 2019)

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Resource NameResource TypeDescriptionKeywordsResource IDProper CitationParent OrganizationRelated ConditionFunding AgencyRelationReferenceWebsite StatusAlternate IDsAlternate URLsOld URLs
LifeGeneResource, organization portal, biomaterial supply resource, consortium, portal, material resource, data or information resourceSwedish study to get a better understanding of how genes, environment and way of life affect health that will enable access to the longitudinal data on 500,000 participants after ethical approval. Half a million people in Sweden between the ages of 0 and 45 will be recruited as volunteers for 6 to 8 years. People between 18 and 45 will be invited and they may, in turn, bring children and other people that they live with into the project. Participants will be followed for many years with regular online surveys and health checks. Their blood and urine samples will also be stored in a biobank. All the data will form a very large information base, where researchers can follow what happens with people''''s health. The LifeGene test center will measure height, hip, waist and chest measurements. A so-called spirometry test will be conducted which measures lung function, a hearing test and bioimpedance measurement (includes weight, BMI and distribution of body fat and muscle mass). They also take blood and urine samples and measure blood pressure and pulse. LifeGene foresees a lot of different research cooperation. Everything from simple withdrawal of longitudinal data, leverage of LifeGene infrastructure and cooperation between LifeGene and complementing scientific projects covering specific areas in more depth. LifeGene will enable access to unique longitudinal data on 500,000 participants available for researchers after ethical approval. LifeGene is also an infrastructure with Test Centers covering most of Sweden, logistics for sample management from arm-to-freezer and state-of-the-art large scale automatic biobanking enabling low cost, high quality, fast withdrawal of biological samples.environment, disease, gene, lifestyle, health, child, adult, longitudinal, genetic test, surveySCR_010524(LifeGene, RRID:SCR_010524)Karolinska Institutet; Stockholm; Sweden General population, VolunteerAFA Foundation, Karolinska Institutet; Stockholm; Sweden, Ragnar Soderberg Foundation, Swedish Research Council, Torsten Foundationrelated to: University of Gothenburg, Gothenburg, Sweden, Karolinska Institutet, Stockholm, Sweden, Lund University, Lund, Sweden, Umea University, Umea, Sweden, Uppsala University, Uppsala, Sweden, Linkoping University, Linkoping, Sweden, listed by: One Mind Biospecimen Bank ListingLast checked downnlx_20757
Sanford Burnham Prebys Medical Discovery Institute Tumor AnalysisResource, group, biomaterial supply resource, core facility, service resource, access service resource, material resourceFacility that provides analysis of animal models of human cancer and other diseases. It provides investigators access to a wide variety of human cancer cell lines for xenograft studies, some primary human xenograft models and additional transgenic mouse solid tumors and leukemia models. The core also offers serial passaging of tumors and derivation of 2D and 3D cultures from xenograft tumors, including patient-derived xenograft (PDX) models. These short-term cell cultures established from PDXs enable in vitro analysis including high throughput screening with compounds or RNAi for functional characterization.animal, cancer, disease, tumor, xenograft, transgenic, mouse, leukemia, patient derived xenograft, pdx, rna, functional characterizationSCR_014858(Sanford Burnham Prebys Medical Discovery Institute Tumor Analysis, RRID:SCR_014858)Last checked down
Washington National Primate Research CenterResource, topical portal, organism supplier, organism-related portal, biomaterial supply resource, portal, material resource, data or information resourceCenter that aims to provide an environment to support biomedical research directed towards human health issues and nonhuman primate health and biology. To meet this mission, the WaNPRC supports biomedical research activities, professional research staff, specifically bred and maintained nonhuman primate colonies, and dedicated facilities and equipment required for nonhuman primate research protocols.aids, clinical, disease, monkey, developmental biology, functional genomics, immunology, reproduction, biology, neurophysiology, infectious disease, transplantation, stem cell, biology, virology, disease model, animal model, neurobiology, neuroscience, systems biology, baboon, long-tailed macaque, rhesus monkey, live animal, macaca nemestrina, macaca fascicularis, macaca mulatta, papio cynocephalus, papio anubisSCR_002761(Washington National Primate Research Center, RRID:SCR_002761) National Center for Research Resources - Primate Resources , University of Washington; Seattle; USA NCRR, NIH Office of the Directorlisted by: One Mind Biospecimen Bank ListingLast checked downnif-0000-24361
GenomEUtwinResource, disease-related portal, topical portal, database, biomaterial supply resource, research forum portal, portal, material resource, data or information resourceTHIS RESOURCE IS NO LONGER IN SERVICE, documented August 29, 2016. Study of genetic and life-style risk factors associated with common diseases based on analysis of European twins. The population cohorts used in the Genomeutwin study consist of Danish, Finnish, Italian, Dutch, English, Australian and Swedish twins and the MORGAM population cohort. This project will apply and develop new molecular and statistical strategies to analyze unique European twin and other population cohorts to define and characterize the genetic, environmental and life-style components in the background of health problems like obesity, migraine, coronary heart disease and stroke, representing major health care problems worldwide. The participating 8 twin cohorts form a collection of over 0.6 million pairs of twins. Tens of thousands of DNA samples with informed consents for genetic studies of common diseases have already been stored from these population-based twin cohorts. Studies targeted to cardiovascular traits are now being undertaken in MORGAM, a prospective case-cohort study. MORGAM cohorts include approximately 6000 individuals, drawn from population-based cohorts consisting of more than 80 000 participants who have donated DNA samples.genetic, environment, lifestyle, gene, diseaseSCR_002843(GenomEUtwin, RRID:SCR_002843)University of Helsinki; Helsinki; Finland TwinEuropean Unionrelated to: KI Biobank - TwinGene, listed by: One Mind Biospecimen Bank ListingLast checked downnif-0000-25218
Human Tissue and Organ Resource for ResearchResource, biomaterial supply resource, tissue bank, service resource, storage service resource, material resource, material storage repositoryNonprofit organization that procures and distributes normal and diseased human biomaterials, tissues, and organs to biomedical researchers in academia, government, and industry. NDRI has developed a nationwide network of tissue collection partners to recover, preserve and distribute biomaterials, tissues, and organs annually to researchers.tissue, organ, nervous system, pulmonary system, cardiovascular system, endocrine system, eye, bone, cartilage, normal, diseased, human immunodeficiency virus, heart, kidney, lung, brain, liver, eye, bone, joint, disease, rare disease, endocrinology, eye bank, immunology, infectious disease, nephrology, nervous system, ophthalmology, pathology, pulmonary system, research, specimen, toxicology, transplantation, catalogSCR_002859(Human Tissue and Organ Resource for Research, RRID:SCR_002859) National Disease Research Interchange , National Center for Research Resources Normal, Disease, Human immunodeficiency virus, Rare diseaseNIH Office of the Directorlisted by: One Mind Biospecimen Bank ListingLast checked downnif-0000-25417
Special Mouse Strains ResourceResource, biomaterial supply resource, material resource, organism supplierResource of special strains of mice that are valuable tools for genetic analysis of complex diseases. They include panels of recombinant inbred (RI) and chromosome substitution (CS) strains.strain panel, frozen, cryopreserved, recombinant inbred mouse, chromosome substitution mouse, consomic strain, gene, disease, strainSCR_002885(Special Mouse Strains Resource, RRID:SCR_002885)Jackson Laboratory Recombinant inbred mouse, Chromosome substitution mouse, Consomic strainNCRR, NIH Office of the Directorrelated to: One Mind Biospecimen Bank Listing, Mouse Phenome Database (MPD), listed by: One Mind Biospecimen Bank ListingLast checked downnif-0000-25593
Hungarian Neurological-Psychiatric BiobankResource, biomaterial supply resource, material resource, tissue bank, data or information resourceThe Hungarian Society of Clinical Neurgenetics established a nationwide collaboration for prospective collection of human biological materials and databases from patient with neurological and psychiatric diseases. The basic triangle of the NEPSYBANK is the sample, the information and the study management. The present participants of the NEPSYBANK are the Department of Neurology and Psychiatry of the four Medical Universities (in Budapest, Debrecen, Pecs, Szeged) and the National Institute of Psychiatry and Neurology in Budapest. The NEPSYBANK is a disease based biobank collecting both phenotypical and environmental data and biological materials such as DNA/RNA, whole blood, plasma, cerebral spinal fluid, muscle / nerve / skin biopsy, brain, and fibroblast. The target of the diseases is presently (Phase I): stroke syndromes, dementias, movement disorders, motoneuron diseases, epilepsy, multiple sclerosis, schizophrenia, alcohol addiction. In the near future (Phase II.) it is planned to enlarge the scale with headaches, disorders of the peripheral nerves, disorders of neuromuscular transmission, disorders of skeletal muscle, depression, anxiety. DNA/RNA is usually extracted from whole blood, but occasionally different tissues such as muscle, brain etc. can be used as well. The extracting procedures differ among the institutes, but in all cases the concentration and the quality of the DNA/RNA must be registered in the database. Participating institutional biobanks have committed themselves to follow common quality standards, which provide access to samples after prioritization on scientific grounds only. In every case the following data are registered. 1. General data: main bank categories, age, sex, ethnicity, body height, body weight, economic stats, education, type of place of living, marital status, birth complications, alcohol, drugs, smoking. 2. Sample properties (sample ID, type of sample, date of extraction, concentration, and level of purity). General patient data as blood pressure, heart rate, internal medical status, ECG, additional diseases. Disease specific question e.g. in schizophrenia the diagnosis after DSMIV and ICD 10, detailed diagnostic questions after both classification, detailed psychiatric and neurological status, laboratory findings, rating scales, data of neuroimaging, genetic tests, applied medication (with generic name, dose, duration), adverse drug effects and other treatments. The Biobank Information Management System (BIMS) is responsible for linkage of databases containing information on the individual sample donors. If you want to have samples from the NEPSYBANK an application must be submitted containing the following information: short research plan including aims and study design, ethic application with a positive decision, specific demands regarding the right of disposition, agreements with grant organizations which regulate immaterial property, information about financing (academic grants, support from industry). All participants have the right to withdraw their samples through a simple order.neurology, psychiatry, genomic, gene, genetic, disease, phenotype, clinical data, environment, dna, rna, whole blood, plasma, cerebral spinal fluid, muscle, biopsy, nerve, skin, brain, fibroblast, tissue, blood, frozen, liquid nitrogen, neurological disease, psychiatric disease, stroke, dementia, movement disorder, motor neuron disease, epilepsy, multiple sclerosis, schizophrenia, alcohol, addiction, alcohol addiction, headache, peripheral nerve disorder, neuromuscular transmission disorder, skeletal muscle disorder, depressive disorder, anxietySCR_003715(Hungarian Neurological-Psychiatric Biobank, RRID:SCR_003715)Neurological disease, Psychiatric disease, Stroke, Dementia, Movement disorder, Motor Neuron Disease, Epilepsy, Multiple Sclerosis, Schizophrenia, Alcohol addiction, Headache, Peripheral nerve disorder, Neuromuscular transmission disorder, Skeletal muscle disorder, Depressive Disorder, Anxietylisted by: One Mind Biospecimen Bank ListingPMID:17448454Last checked downnlx_13478
Biospecimens/Biorepositories: Rare Disease-HUB (RD-HUB)Resource, biomaterial supply resource, data or information resource, material resource, databaseA database of biospecimens collected, stored, and distributed by biorepositories in the United States and around the globe. Its goals are: To help and assist interested parties and investigators search, locate, and identify desired biospecimens needed for their research; to facilitate collaboration and sharing of material and data among investigators across the globe; to accelerate research to facilitate the discovery of new treatments, therapeutics and eventually cures for rare diseases as well as common diseases; to identify, locate and increase the awareness of existing biorepositories across the globe; and to link the RD-HUB with the Global Rare Diseases Patient Registry and Data Repository (GRDR).rare disease, disease, publicSCR_004327(Biospecimens/Biorepositories: Rare Disease-HUB (RD-HUB), RRID:SCR_004327)Office of Rare Diseases Research Rare disease, AgingNIHrelated to: GRDR, listed by: NIH Data Sharing Repositories, One Mind Biospecimen Bank Listing, Accelerated Cure Project MS Repository, Cooperative Human Tissue Network Western Division at Vanderbilt University Medical Center, NIDDK Information Network, lists: NIDDK Central Repository, National Disease Research InterchangeLast checked downnlx_143682
SepNet Central Sample BankResource, biomaterial supply resource, service resource, storage service resource, material storage repository, material resource, data or information resourceIt is the aim of the SepNet initiative to establish a central facility, essential to data and sample quality and homogeneity, that comprises a structured and easily accessible sample bank with probes of homogeneous quality originating from a well-characterized patient population enrolled in independent, innovative and internationally competitive prospective clinical sepsis trials. The SepNetBiobank is a core facility of SepNet. The object of this central sample resource is to organize and handle all relevant aspects of sampling, storage and delivery of samples in the SepNet collaboration to ensure homogeneity of the samples in terms of specimen quality and maintaining sampling standards. This will be achieved through central handling of samples collected in peripheral nationwide 17 regional centers and an additional 36 associated centers according to an agreed sampling scheme and pre-set standards for sample quality, sample handling and banking; quality assurance and all relevant parts of sample handling will be in the hands of the core unit, minimizing pre-analytical steps in the heterogeneous environment of the different regional centers. In the next few months a fully automated sample storage system will be implemented that allows handling of more than 200.000 individual aliquots expected after completion of the different ongoing and planned SepNet Trails. In the next six months a fully automated -80 degree C sample storage system will be implemented. After completion of the plannend and ongoing SepNet trials more than 59.710 expected primary samples (218.040 aliquots) will be stored in this system. This outstanding sample resource will provide the basis for scientific projects aming at improving patient care with sepsis e.g. advancement in diagnostics, risk stratification, therapy and outcome.dna, peripheral blood, blood, serum, plasma, infectious disease, sepsis, infection, parasitic disease, disease, parasite, clinical sepsis trial, clinical, gene, gene expression, phenotype, frozen, clinical trialSCR_004543(SepNet Central Sample Bank, RRID:SCR_004543)Infectious disease, Sepsis, Infection, Parasitic disease, DiseaseGerman Federal Ministry of Research and Educationlisted by: One Mind Biospecimen Bank ListingLast checked downnlx_53583
Telethon Network of Genetic BiobanksResource, data or information resource, production service resource, biomaterial supply resource, database, tissue bank, material service resource, catalog, service resource, storage service resource, biobank, data repository, material resource, material storage repositoryNetwork of non profit association of Italian repositories to form catalogue of biospecimens and associated data. Used to collect, process, preserve and distribute biological samples and related clinical data from individuals affected by rare diseases, their relatives or from healthy control individuals, with standards complying with Italian laws and international recommendations. You may browse sample catalogue by diagnosis or use advanced search option. Request for samples is granted only if project is in agreement with TNGB mission and after receiving signed material transfer agreement form.Italian, repository, catalogue, biospeciment, data, collect, process, preserve, distribute, rare, diseaseSCR_004658(Telethon Network of Genetic Biobanks, RRID:SCR_004658)Telethon Foundation Italian Health Department, Telethon Foundationlisted by: One Mind Biospecimen Bank Listing, affiliated with: EuroBioBankPMID:24004821Last checked downnlx_65989
Wistar Institute Collection at CoriellResource, biomaterial supply resource, material resource, institution, cell repositoryCollection of cell lines developed by Wistar scientists that includes a group of hybridomas that produce monoclonal antibodies that are useful in influenza research and vaccine development, melanoma cell lines derived from patients with diseases ranging from mild dysplasia to advanced metastatic cancer and a range of human endothelial cell lines.hybridoma, monoclonal antibody, antibody, cell line, melanoma cell line, endothelial cell line, smooth muscle cell line, disease, cancer, dysplasia, metastatic cancerSCR_004660(Wistar Institute Collection at Coriell, RRID:SCR_004660)Coriell Cell Repositories , Wistar Institute Disease, Cancer, Dysplasia, ( Diseases ranging from mild dysplasia to advanced metastatic cancer )listed by: One Mind Biospecimen Bank ListingLast checked downnlx_143856
UMKC Neuroscience Brain Tissue Bank and Research LaboratoryResource, biomaterial supply resource, tissue bank, service resource, brain bank, storage service resource, material resource, material storage repositoryTHIS RESOURCE IS NO LONGER IN SERVICE, documented August 31, 2016. The UMKC Neuroscience Brain Tissue Bank and Research Laboratory has been established to obtain, process, and distribute human brain tissue to qualified scientists and clinicians dedicated to neuroscience research. No other living organ approaches the human brain in complexity or capacity. Healthy, it astounds and inspires miracles. Diseased, it confounds and diminishes hope. The use of human brain tissue for research will provide insight into the anatomical and neurochemical aspects of diseased and non-diseased brains. While animal models are helpful and necessary in understanding disease, certain disorders can be more efficiently studied using human brain tissue. Also, modern research techniques are often best applied to human tissue. We also need samples of brain tissue that have not been affected by disease. They help us to compare a 'normal' brain with a diseased one. Also, we have a critical need for brain donations from relatives who have genetically inherited disorders. Tissue preparation consists of fresh quick-frozen tissue blocks or coronal slices (nitrogen vapor frozen; custom dissection of specific anatomic regions) or formalin-fixed coronal slices (custom dissection of specific anatomic regions).brain tissue, brain, tissue, fresh quick-frozen, block, nitrogen vapor frozen, frozen, formalin-fixed, disease, normal, genetically inherited disorder, normal control, matched control, neuroscience, post-mortem, coronal sliceSCR_005148(UMKC Neuroscience Brain Tissue Bank and Research Laboratory, RRID:SCR_005148)University of Missouri-Kansas City School of Medicine; Missouri; USA Disease, Normal, Genetically inherited disorder, Normal control, Matched controllisted by: One Mind Biospecimen Bank ListingLast checked downnlx_144161
Geisinger BiobankResource, biomaterial supply resource, material resource, data or information resourceBy collecting and analyzing blood samples from Geisinger''s large patient population, MyCode will help unlock the mysteries of some of the most devastating and debilitating diseases. Blood samples are obtained from patients of certain Geisinger specialty clinics to study specific conditions, such as obesity and cardiovascular disease, and also from patients of Geisinger primary care clinics to provide a representative sample of the regional population. More than 60,000 samples from over 23,000 Geisinger patients have been collected so far, and sample collection is ongoing. MyCode researchers use the blood samples to study the genetic causes of diseases and certain disease-related molecular mediators. Knowledge gained from these studies will allow researchers to pursue innovative approaches to disease prevention, diagnosis and treatment. To be of value for Genomic Medicine research, bio-banked samples must be connected to clinical data: MyCode allows genetic and molecular data about the samples to be connected to medical data in a way that protects patient identity. When a patient agrees to participate in MyCode, blood samples for the MyCode Project are collected during blood draws ordered as part of the patient''s routine medical care. After the sample is drawn and labeled, a staff member from the Weis Center for Research transports the blood to the Geisinger Clinic Genomics Core (GCGC) where it is processed for storage. At this stage, all personal identification markers are removed and the samples are assigned a randomly-selected identification number. A secure key is maintained that allows approved researchers to connect the samples to the clinical data for genomic studies in a way that ensures confidentiality of the information. To maintain confidentiality of MyCode data the code linking the research numbers and the electronic health records are kept in a password-protected files accessible only to MyCode team members. Additionally, all results generated from the samples are reported as a group so that individuals are not identified. The samples are stored indefinitely.gene, genetics, disease, clinical data, genomic medicine, genetic data, molecular data, blood, obesity, cardiovascular disease, other specific conditions, regional populationSCR_005652(Geisinger Biobank, RRID:SCR_005652)Obesity, Cardiovascular disease, Disease, Other conditions, Regional populationBen Franklin Technology Development Authority, Geisinger Clinic Administrative Committee for Researchlisted by: One Mind Biospecimen Bank ListingLast checked downnlx_14718
KI Biobank - SATSAResource, disease-related portal, topical portal, research forum portal, biomaterial supply resource, portal, material resource, data or information resourceLongitudinal twin study to understand individual differences in aging with corresponding data and biological samples. The twin design and the inclusion of twins reared apart makes it possible to study the importance of genetic and environmental factors that may underlie differing aging outcomes. Further, the broad spectrum of biological, psychological, and social domains assessed across the life span makes it possible to study patterns of change within and across domains and how these predict health and diseases of aging. The study is comprised of several longitudinal components including, a comprehensive questionnaire that was sent to all twins in the Swedish Twin Registry who were separated at an early age and reared apart and a control sample of twins reared together. The questionnaires include items concerning rearing, family, adult, and working environment, health status, health related behaviors (e.g. alcohol, tobacco, and dietary habits) as well as relationships, and personality measures. The questionnaires were sent again at 3 year intervals in 1987, 1990, 1993 and after a break again in 2004, 2007, and 2010. Thus far more than 2,000 twins have responded to at least one of the seven questionnaire assessments conducted between 1984 and 2010. Additionally there is information about midlife life style factors from the Swedish Twin Registry that were collected about twenty years before SATSA started. In the second component a subsample of 861 individuals have participated in at least one wave of in-person testing (IPT). The first IPT started in 1986 and since then eight IPTs have been collected and the last wave will be collected during 2012-2013. The IPT includes a health examination, structured interviews, tests of functional capacity, and memory and thinking abilities. To date, over 76% of the sample has participated in 3 or more measurement waves. At IPT9 a third component was added to SATSA, a measure of day-to-day fluctuations in memory and thinking abilities, and emotions. Information about social interactions is also collected. After the visit by the research nurses the twins fill out the day-to-day booklet during the next five days. This procedure will be repeated in IPT10. This will add information about small and short-term changes and more changes are supposed to indicate the beginning of poor health. Data from SATSA can be used to study various aspects of aging. For example, the relative importance of genetic and environmental factors for individual differences in aging especially in cognitive and physical domains has been studied. A further main focus is to study changes within and across domains and which genetic and life style factors predict these changes. Given the wide spectrum of data from measured genes to social relationships collected over more than two decades they dare to say that SATSA is a unique study, with the possibility to answer many questions within gerontology and geriatrics. Types of samples * Serum * DNA Number of sample donors: 674 (June 2010)gene, environment, health, disease, longitudinal, questionnaire, life style, interview, functional capacity, memory, thinking, emotion, social interaction, cognitive, physical, behavior, relationship, personality, healthSCR_005966(KI Biobank - SATSA, RRID:SCR_005966)Karolisnka Biobank Aging, Twin, Control, (reared apart vs. reared together)MacArthur Foundation Research Network on Successful Aging, NIA, Swedish Council for Working Life and Social Research, Swedish Research Councilrelated to: KI Biobank - HARMONY, uses: Swedish Twin Registry, listed by: One Mind Biospecimen Bank ListingLast checked downnlx_151325,
KI Biobank - STAGEResource, disease-related portal, topical portal, research forum portal, biomaterial supply resource, data set, portal, material resource, data or information resourceTHIS RESOURCE IS NO LONGER IN SERVCE, documented September 2, 2016. The Swedish twin registry has recently examined all twins in Sweden born between 1959-1985. 25,000 individuals participated in the study. The twins had to implement a Web-based survey on the Internet or a telephone interview where we had to answer questions about, among other things, about the diseases they have, or have had, behaviors, eating and drinking habits, smoking habits, etc. The aim of the study is to extend the information in the Swedish twin registry. Our goal with twin studies are, inter alia, to study the relative importance of the heritage and environment for the emergence of various diseases. The responses from the study is currently the basis for a number of analyses regarding how inheritance and environment affects disease and tobacco habits. Currently third follow-up STAGE where 10,000 twins that had previously taken part are contacted again. The purpose of alteplase randomized controlled trials is to follow up the same individuals one year after the first and second questionnaire replies were received to see if anything has changed. The issues we are interested in the follow-up to include changes in general health, working and living situation, your weight, smoking habits, etc. Study Results The results we have so far come to and which we can present here are figures on the prevalence of certain diseases. The figures give a rough estimate of the incidence of these diseases will look for all individuals, born in Sweden in 1959-1985. The figures are based on the questions on the questionnaire which the twins themselves had to answer whether they have or have had various, gene, environment, survey, interview, disease, behavior, eating habit, drinking habit, questionnaire, nicotine, smoking, nicotine use disorderSCR_006004(KI Biobank - STAGE, RRID:SCR_006004)Karolisnka Biobank Twinrelated to: Swedish Twin Registry, listed by: One Mind Biospecimen Bank ListingLast checked downnlx_151384
BayGenomicsResource, biomaterial supply resource, material resource, organism supplier, tissue bankTHIS RESOURCE IS NO LONGER IN SERVICE, documented August 29, 2016. The BayGenomics gene-trap resource provides researchers with access to thousands of mouse embryonic stem (ES) cell lines harboring characterized insertional mutations in both known and novel genes. The major goal of BayGenomics is to identify genes relevant to cardiovascular and pulmonary disease.embryonic, expression, gene, bioinformatic, cardiopulmonary, cell, clone, disease, genomic, germline, insertional, line, mouse, mutant, mutation, pulmonary, stem, cardiovascular, pulmonary diseaseSCR_008168(BayGenomics, RRID:SCR_008168)University of California at San Francisco; California; USA listed by: One Mind Biospecimen Bank ListingLast checked downnif-0000-21042
National Resource for AplysiaResource, biomaterial supply resource, material resource, organism supplierCenter where Aplysia californica are cultured and raised for research purposes. Aplysia from the facility serve in research on genomics, human brain function, toxicology for developmental studies, natural products, chemistry for isolation of novel anti-tumor and antibacterial compounds, in the study of transport by digestive tissues and have potential for use in studies of substance addiction and nerve senescence and regeneration.disease, genomics, aplysia californica, research, brainSCR_008361(National Resource for Aplysia, RRID:SCR_008361)University of Miami; Florida; USA NCRR, NIH Office of the DirectorLast checked downnif-0000-25472
Induced Mutant ResourceResource, organism supplier, production service resource, biomaterial supply resource, material service resource, service resource, storage service resource, material resource, biomaterial manufacture, material storage repositoryTHIS RESOURCE IS NO LONGER IN SERVICE, documented on June 08, 2012. The function of the IMR is to select, import, cryopreserve, maintain, and distribute these important strains of mice to the research community. To improve their value for research, the IMR also undertakes genetic development of stocks, such as transferring mutant genes or transgenes to defined genetic backgrounds and combining transgenes and/or targeted mutations to create new mouse models for research. The function of the IMR is to: * select biomedically important stocks of transgenic, chemically induced, and targeted mutant mice * import these stocks into the Jackson Laboratory by rederivation procedures that rid them of any pathogens they might carry * cryopreserve embryos from these stocks to protect them against accidental loss and genetic contamination * backcross the mutation onto an inbred strain, if necessary * distribute them to the scientific community More than 1000 mutant stocks have been accepted by the IMR from 1992 through December 2006. Current holdings include models for research on cancer; breast cancer; immunological and inflammatory diseases; neurological diseases; behavioral, cardiovascular and heart diseases; developmental, metabolic and other diseases; reporter (e.g., GFP) and recombinase (e.g., cre/loxP) strains. About eight strains a month are being added to the IMR holdings. Research is being conducted on improved methods for assisted reproduction and speed congenic production. Most of the targeted mutants arrive on a mixed 129xC57BL/6 genetic background, and as many of these as possible are backcrossed onto an inbred strain (usually C57BL/6J). In addition, new mouse models are being created by intercrossing carriers of specific transgenes and/or targeted mutations. Simple sequence length polymorphism DNA markers are being used to characterize and evaluate differences between inbred strains, substrains, and embryonic stem cell lines.embryo, genetic, behavioral, biomedical, breast cancer, cancer, cardiovascular, chemical, cre, cryopreserved, developmental, disease, distribution, dna, gfp, heart, immunological, inflammatory, loxp, marker, metabolic, model, mouse, mutation, neurological, pathogen, polymorphism, recombinase, research, stock, targeting, transgeneSCR_008366(Induced Mutant Resource, RRID:SCR_008366)Jackson Laboratory American Cancer Society, American Heart Association, Amyotrophic Lateral Sclerosis Association, Cystic Fibrosis Foundation, Department of the Army Breast Cancer Research Initiative., Howard Hughes Medical Institute, March of Dimes Birth Defects Foundation, National Multiple Sclerosis Society, NCRR, NIAID, NIAMSLast checked downnif-0000-25566
Alamogordo Primate FacilityResource, biomaterial supply resource, service resource, material resource, organism supplier, storage service resourceTHIS RESOURCE IS NO LONGER IN SERVICE, documented on July 17, 2013. It houses chimpanzees that have been used in biomedical research, but no active, invasive research is conducted on the site. The APF provides for the long-term care and husbandry of chimpanzees that have been used in biomedical research. Charles River Laboratories Inc. operates the facility under contract with the National Institutes of Health. To be used in continuing virological research, the animals must be transferred to active chimpanzee research settings. All chimpanzees at the APF have been exposed to various microorganisms, such as hepatitis C virus and HIV. For this reason, they may be candidates for studies related to these diseases. The National Center for Research Resources (NCRR) may remove infected animals from the APF to other accredited chimpanzee facilities for research purposes. Investigators interested in the chimpanzees at the APF should contact Dr. Harold Watson in NCRR''s Division of Comparative Medicine to discuss research requirements.animal, biomedical, chimpanzee, comparative medicine, disease, hepatitis c, hiv, husbandry, infection, microorganism, primate, research, virological, virusSCR_008376(Alamogordo Primate Facility, RRID:SCR_008376)NCRRLast checked downnif-0000-25894
Rutgers Cell and DNA RepositoryResource, biomaterial supply resource, data or information resource, material resource, cell repositoryRUCDR is a biobank and a service organization that maintains human blood, serum, saliva, tissue and the genetic products derived from those. Services include technical consultation and logistical support for biobanking. Researchers can order biomaterials and apply for phenotypic / genotypic data.genetics, disease, phenotypic data, genotypic data, cell, dna, blood, cell lineSCR_010624(Rutgers Cell and DNA Repository, RRID:SCR_010624)Rutgers University; New Jersey; USA related to: NIMH Center for Collaborative Genetic Studies on Mental Disorders, listed by: One Mind Biospecimen Bank ListingLast checked upnlx_60990
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