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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

(last updated: Oct 12, 2019)

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Resource NameResource TypeDescriptionKeywordsResource IDProper CitationParent OrganizationRelated ConditionFunding AgencyRelationReferenceWebsite StatusAlternate IDsAlternate URLsOld URLs
LifeGeneResource, organization portal, biomaterial supply resource, consortium, portal, material resource, data or information resourceSwedish study to get a better understanding of how genes, environment and way of life affect health that will enable access to the longitudinal data on 500,000 participants after ethical approval. Half a million people in Sweden between the ages of 0 and 45 will be recruited as volunteers for 6 to 8 years. People between 18 and 45 will be invited and they may, in turn, bring children and other people that they live with into the project. Participants will be followed for many years with regular online surveys and health checks. Their blood and urine samples will also be stored in a biobank. All the data will form a very large information base, where researchers can follow what happens with people''''s health. The LifeGene test center will measure height, hip, waist and chest measurements. A so-called spirometry test will be conducted which measures lung function, a hearing test and bioimpedance measurement (includes weight, BMI and distribution of body fat and muscle mass). They also take blood and urine samples and measure blood pressure and pulse. LifeGene foresees a lot of different research cooperation. Everything from simple withdrawal of longitudinal data, leverage of LifeGene infrastructure and cooperation between LifeGene and complementing scientific projects covering specific areas in more depth. LifeGene will enable access to unique longitudinal data on 500,000 participants available for researchers after ethical approval. LifeGene is also an infrastructure with Test Centers covering most of Sweden, logistics for sample management from arm-to-freezer and state-of-the-art large scale automatic biobanking enabling low cost, high quality, fast withdrawal of biological samples.environment, disease, gene, lifestyle, health, child, adult, longitudinal, genetic test, surveySCR_010524(LifeGene, RRID:SCR_010524)Karolinska Institutet; Stockholm; Sweden General population, VolunteerAFA Foundation, Karolinska Institutet; Stockholm; Sweden, Ragnar Soderberg Foundation, Swedish Research Council, Torsten Foundationrelated to: University of Gothenburg, Gothenburg, Sweden, Karolinska Institutet, Stockholm, Sweden, Lund University, Lund, Sweden, Umea University, Umea, Sweden, Uppsala University, Uppsala, Sweden, Linkoping University, Linkoping, Sweden, listed by: One Mind Biospecimen Bank ListingLast checked downnlx_20757http://lifegene.ki.se/working_groups/sampling_en.html
Washington National Primate Research CenterResource, topical portal, organism supplier, organism-related portal, biomaterial supply resource, portal, material resource, data or information resourceCenter that aims to provide an environment to support biomedical research directed towards human health issues and nonhuman primate health and biology. To meet this mission, the WaNPRC supports biomedical research activities, professional research staff, specifically bred and maintained nonhuman primate colonies, and dedicated facilities and equipment required for nonhuman primate research protocols.aids, clinical, disease, monkey, developmental biology, functional genomics, immunology, reproduction, biology, neurophysiology, infectious disease, transplantation, stem cell, biology, virology, disease model, animal model, neurobiology, neuroscience, systems biology, baboon, long-tailed macaque, rhesus monkey, live animal, macaca nemestrina, macaca fascicularis, macaca mulatta, papio cynocephalus, papio anubisSCR_002761(Washington National Primate Research Center, RRID:SCR_002761) National Center for Research Resources - Primate Resources , University of Washington; Seattle; USA NCRR, NIH Office of the Directorlisted by: One Mind Biospecimen Bank ListingLast checked downnif-0000-24361https://orip.nih.gov/comparative-medicine/programs/vertebrate-modelshttp://www.wanprc.org/WaNPRC/index.php
GenomEUtwinResource, disease-related portal, topical portal, database, biomaterial supply resource, research forum portal, portal, material resource, data or information resourceTHIS RESOURCE IS NO LONGER IN SERVICE, documented August 29, 2016. Study of genetic and life-style risk factors associated with common diseases based on analysis of European twins. The population cohorts used in the Genomeutwin study consist of Danish, Finnish, Italian, Dutch, English, Australian and Swedish twins and the MORGAM population cohort. This project will apply and develop new molecular and statistical strategies to analyze unique European twin and other population cohorts to define and characterize the genetic, environmental and life-style components in the background of health problems like obesity, migraine, coronary heart disease and stroke, representing major health care problems worldwide. The participating 8 twin cohorts form a collection of over 0.6 million pairs of twins. Tens of thousands of DNA samples with informed consents for genetic studies of common diseases have already been stored from these population-based twin cohorts. Studies targeted to cardiovascular traits are now being undertaken in MORGAM, a prospective case-cohort study. MORGAM cohorts include approximately 6000 individuals, drawn from population-based cohorts consisting of more than 80 000 participants who have donated DNA samples.genetic, environment, lifestyle, gene, diseaseSCR_002843(GenomEUtwin, RRID:SCR_002843)University of Helsinki; Helsinki; Finland TwinEuropean Unionrelated to: KI Biobank - TwinGene, listed by: One Mind Biospecimen Bank ListingLast checked downnif-0000-25218
Human Tissue and Organ Resource for ResearchResource, biomaterial supply resource, tissue bank, service resource, storage service resource, material resource, material storage repositoryNonprofit organization that procures and distributes normal and diseased human biomaterials, tissues, and organs to biomedical researchers in academia, government, and industry. NDRI has developed a nationwide network of tissue collection partners to recover, preserve and distribute biomaterials, tissues, and organs annually to researchers.tissue, organ, nervous system, pulmonary system, cardiovascular system, endocrine system, eye, bone, cartilage, normal, diseased, human immunodeficiency virus, heart, kidney, lung, brain, liver, eye, bone, joint, disease, rare disease, endocrinology, eye bank, immunology, infectious disease, nephrology, nervous system, ophthalmology, pathology, pulmonary system, research, specimen, toxicology, transplantation, catalogSCR_002859(Human Tissue and Organ Resource for Research, RRID:SCR_002859) National Disease Research Interchange , National Center for Research Resources Normal, Disease, Human immunodeficiency virus, Rare diseaseNIH Office of the Directorlisted by: One Mind Biospecimen Bank ListingLast checked downnif-0000-25417https://orip.nih.gov/comparative-medicine/programs/genetic-biological-and-information-resources
Special Mouse Strains ResourceResource, biomaterial supply resource, material resource, organism supplierResource of special strains of mice that are valuable tools for genetic analysis of complex diseases. They include panels of recombinant inbred (RI) and chromosome substitution (CS) strains.strain panel, frozen, cryopreserved, recombinant inbred mouse, chromosome substitution mouse, consomic strain, gene, disease, strainSCR_002885(Special Mouse Strains Resource, RRID:SCR_002885)Jackson Laboratory Recombinant inbred mouse, Chromosome substitution mouse, Consomic strainNCRR, NIH Office of the Directorrelated to: One Mind Biospecimen Bank Listing, Mouse Phenome Database (MPD), listed by: One Mind Biospecimen Bank ListingLast checked downnif-0000-25593
Hungarian Neurological-Psychiatric BiobankResource, biomaterial supply resource, material resource, tissue bank, data or information resourceThe Hungarian Society of Clinical Neurgenetics established a nationwide collaboration for prospective collection of human biological materials and databases from patient with neurological and psychiatric diseases. The basic triangle of the NEPSYBANK is the sample, the information and the study management. The present participants of the NEPSYBANK are the Department of Neurology and Psychiatry of the four Medical Universities (in Budapest, Debrecen, Pecs, Szeged) and the National Institute of Psychiatry and Neurology in Budapest. The NEPSYBANK is a disease based biobank collecting both phenotypical and environmental data and biological materials such as DNA/RNA, whole blood, plasma, cerebral spinal fluid, muscle / nerve / skin biopsy, brain, and fibroblast. The target of the diseases is presently (Phase I): stroke syndromes, dementias, movement disorders, motoneuron diseases, epilepsy, multiple sclerosis, schizophrenia, alcohol addiction. In the near future (Phase II.) it is planned to enlarge the scale with headaches, disorders of the peripheral nerves, disorders of neuromuscular transmission, disorders of skeletal muscle, depression, anxiety. DNA/RNA is usually extracted from whole blood, but occasionally different tissues such as muscle, brain etc. can be used as well. The extracting procedures differ among the institutes, but in all cases the concentration and the quality of the DNA/RNA must be registered in the database. Participating institutional biobanks have committed themselves to follow common quality standards, which provide access to samples after prioritization on scientific grounds only. In every case the following data are registered. 1. General data: main bank categories, age, sex, ethnicity, body height, body weight, economic stats, education, type of place of living, marital status, birth complications, alcohol, drugs, smoking. 2. Sample properties (sample ID, type of sample, date of extraction, concentration, and level of purity). General patient data as blood pressure, heart rate, internal medical status, ECG, additional diseases. Disease specific question e.g. in schizophrenia the diagnosis after DSMIV and ICD 10, detailed diagnostic questions after both classification, detailed psychiatric and neurological status, laboratory findings, rating scales, data of neuroimaging, genetic tests, applied medication (with generic name, dose, duration), adverse drug effects and other treatments. The Biobank Information Management System (BIMS) is responsible for linkage of databases containing information on the individual sample donors. If you want to have samples from the NEPSYBANK an application must be submitted containing the following information: short research plan including aims and study design, ethic application with a positive decision, specific demands regarding the right of disposition, agreements with grant organizations which regulate immaterial property, information about financing (academic grants, support from industry). All participants have the right to withdraw their samples through a simple order.neurology, psychiatry, genomic, gene, genetic, disease, phenotype, clinical data, environment, dna, rna, whole blood, plasma, cerebral spinal fluid, muscle, biopsy, nerve, skin, brain, fibroblast, tissue, blood, frozen, liquid nitrogen, neurological disease, psychiatric disease, stroke, dementia, movement disorder, motor neuron disease, epilepsy, multiple sclerosis, schizophrenia, alcohol, addiction, alcohol addiction, headache, peripheral nerve disorder, neuromuscular transmission disorder, skeletal muscle disorder, depressive disorder, anxietySCR_003715(Hungarian Neurological-Psychiatric Biobank, RRID:SCR_003715)Neurological disease, Psychiatric disease, Stroke, Dementia, Movement disorder, Motor Neuron Disease, Epilepsy, Multiple Sclerosis, Schizophrenia, Alcohol addiction, Headache, Peripheral nerve disorder, Neuromuscular transmission disorder, Skeletal muscle disorder, Depressive Disorder, Anxietylisted by: One Mind Biospecimen Bank ListingPMID:17448454Last checked downnlx_13478
SepNet Central Sample BankResource, biomaterial supply resource, service resource, storage service resource, material storage repository, material resource, data or information resourceIt is the aim of the SepNet initiative to establish a central facility, essential to data and sample quality and homogeneity, that comprises a structured and easily accessible sample bank with probes of homogeneous quality originating from a well-characterized patient population enrolled in independent, innovative and internationally competitive prospective clinical sepsis trials. The SepNetBiobank is a core facility of SepNet. The object of this central sample resource is to organize and handle all relevant aspects of sampling, storage and delivery of samples in the SepNet collaboration to ensure homogeneity of the samples in terms of specimen quality and maintaining sampling standards. This will be achieved through central handling of samples collected in peripheral nationwide 17 regional centers and an additional 36 associated centers according to an agreed sampling scheme and pre-set standards for sample quality, sample handling and banking; quality assurance and all relevant parts of sample handling will be in the hands of the core unit, minimizing pre-analytical steps in the heterogeneous environment of the different regional centers. In the next few months a fully automated sample storage system will be implemented that allows handling of more than 200.000 individual aliquots expected after completion of the different ongoing and planned SepNet Trails. In the next six months a fully automated -80 degree C sample storage system will be implemented. After completion of the plannend and ongoing SepNet trials more than 59.710 expected primary samples (218.040 aliquots) will be stored in this system. This outstanding sample resource will provide the basis for scientific projects aming at improving patient care with sepsis e.g. advancement in diagnostics, risk stratification, therapy and outcome.dna, peripheral blood, blood, serum, plasma, infectious disease, sepsis, infection, parasitic disease, disease, parasite, clinical sepsis trial, clinical, gene, gene expression, phenotype, frozen, clinical trialSCR_004543(SepNet Central Sample Bank, RRID:SCR_004543)Infectious disease, Sepsis, Infection, Parasitic disease, DiseaseGerman Federal Ministry of Research and Educationlisted by: One Mind Biospecimen Bank ListingLast checked downnlx_53583http://www.tmf-ev.de/Arbeitsgruppen_Foren/AGBMB.aspx
Telethon Network of Genetic BiobanksResource, data or information resource, production service resource, biomaterial supply resource, database, tissue bank, material service resource, catalog, service resource, storage service resource, biobank, data repository, material resource, material storage repositoryNetwork of non profit association of Italian repositories to form catalogue of biospecimens and associated data. Used to collect, process, preserve and distribute biological samples and related clinical data from individuals affected by rare diseases, their relatives or from healthy control individuals, with standards complying with Italian laws and international recommendations. You may browse sample catalogue by diagnosis or use advanced search option. Request for samples is granted only if project is in agreement with TNGB mission and after receiving signed material transfer agreement form.Italian, repository, catalogue, biospeciment, data, collect, process, preserve, distribute, rare, diseaseSCR_004658(Telethon Network of Genetic Biobanks, RRID:SCR_004658)Telethon Foundation Italian Health Department, Telethon Foundationlisted by: One Mind Biospecimen Bank Listing, affiliated with: EuroBioBankPMID:24004821Last checked downnlx_65989
Wistar Institute Collection at CoriellResource, biomaterial supply resource, material resource, institution, cell repositoryCollection of cell lines developed by Wistar scientists that includes a group of hybridomas that produce monoclonal antibodies that are useful in influenza research and vaccine development, melanoma cell lines derived from patients with diseases ranging from mild dysplasia to advanced metastatic cancer and a range of human endothelial cell lines.hybridoma, monoclonal antibody, antibody, cell line, melanoma cell line, endothelial cell line, smooth muscle cell line, disease, cancer, dysplasia, metastatic cancerSCR_004660(Wistar Institute Collection at Coriell, RRID:SCR_004660)Coriell Cell Repositories , Wistar Institute Disease, Cancer, Dysplasia, ( Diseases ranging from mild dysplasia to advanced metastatic cancer )listed by: One Mind Biospecimen Bank ListingLast checked downnlx_143856
UMKC Neuroscience Brain Tissue Bank and Research LaboratoryResource, biomaterial supply resource, tissue bank, service resource, brain bank, storage service resource, material resource, material storage repositoryTHIS RESOURCE IS NO LONGER IN SERVICE, documented August 31, 2016. The UMKC Neuroscience Brain Tissue Bank and Research Laboratory has been established to obtain, process, and distribute human brain tissue to qualified scientists and clinicians dedicated to neuroscience research. No other living organ approaches the human brain in complexity or capacity. Healthy, it astounds and inspires miracles. Diseased, it confounds and diminishes hope. The use of human brain tissue for research will provide insight into the anatomical and neurochemical aspects of diseased and non-diseased brains. While animal models are helpful and necessary in understanding disease, certain disorders can be more efficiently studied using human brain tissue. Also, modern research techniques are often best applied to human tissue. We also need samples of brain tissue that have not been affected by disease. They help us to compare a 'normal' brain with a diseased one. Also, we have a critical need for brain donations from relatives who have genetically inherited disorders. Tissue preparation consists of fresh quick-frozen tissue blocks or coronal slices (nitrogen vapor frozen; custom dissection of specific anatomic regions) or formalin-fixed coronal slices (custom dissection of specific anatomic regions).brain tissue, brain, tissue, fresh quick-frozen, block, nitrogen vapor frozen, frozen, formalin-fixed, disease, normal, genetically inherited disorder, normal control, matched control, neuroscience, post-mortem, coronal sliceSCR_005148(UMKC Neuroscience Brain Tissue Bank and Research Laboratory, RRID:SCR_005148)University of Missouri-Kansas City School of Medicine; Missouri; USA Disease, Normal, Genetically inherited disorder, Normal control, Matched controllisted by: One Mind Biospecimen Bank ListingLast checked downnlx_144161
Geisinger BiobankResource, biomaterial supply resource, material resource, data or information resourceBy collecting and analyzing blood samples from Geisinger''s large patient population, MyCode will help unlock the mysteries of some of the most devastating and debilitating diseases. Blood samples are obtained from patients of certain Geisinger specialty clinics to study specific conditions, such as obesity and cardiovascular disease, and also from patients of Geisinger primary care clinics to provide a representative sample of the regional population. More than 60,000 samples from over 23,000 Geisinger patients have been collected so far, and sample collection is ongoing. MyCode researchers use the blood samples to study the genetic causes of diseases and certain disease-related molecular mediators. Knowledge gained from these studies will allow researchers to pursue innovative approaches to disease prevention, diagnosis and treatment. To be of value for Genomic Medicine research, bio-banked samples must be connected to clinical data: MyCode allows genetic and molecular data about the samples to be connected to medical data in a way that protects patient identity. When a patient agrees to participate in MyCode, blood samples for the MyCode Project are collected during blood draws ordered as part of the patient''s routine medical care. After the sample is drawn and labeled, a staff member from the Weis Center for Research transports the blood to the Geisinger Clinic Genomics Core (GCGC) where it is processed for storage. At this stage, all personal identification markers are removed and the samples are assigned a randomly-selected identification number. A secure key is maintained that allows approved researchers to connect the samples to the clinical data for genomic studies in a way that ensures confidentiality of the information. To maintain confidentiality of MyCode data the code linking the research numbers and the electronic health records are kept in a password-protected files accessible only to MyCode team members. Additionally, all results generated from the samples are reported as a group so that individuals are not identified. The samples are stored indefinitely.gene, genetics, disease, clinical data, genomic medicine, genetic data, molecular data, blood, obesity, cardiovascular disease, other specific conditions, regional populationSCR_005652(Geisinger Biobank, RRID:SCR_005652)Obesity, Cardiovascular disease, Disease, Other conditions, Regional populationBen Franklin Technology Development Authority, Geisinger Clinic Administrative Committee for Researchlisted by: One Mind Biospecimen Bank ListingLast checked downnlx_14718
KI Biobank - SATSAResource, disease-related portal, topical portal, research forum portal, biomaterial supply resource, portal, material resource, data or information resourceLongitudinal twin study to understand individual differences in aging with corresponding data and biological samples. The twin design and the inclusion of twins reared apart makes it possible to study the importance of genetic and environmental factors that may underlie differing aging outcomes. Further, the broad spectrum of biological, psychological, and social domains assessed across the life span makes it possible to study patterns of change within and across domains and how these predict health and diseases of aging. The study is comprised of several longitudinal components including, a comprehensive questionnaire that was sent to all twins in the Swedish Twin Registry who were separated at an early age and reared apart and a control sample of twins reared together. The questionnaires include items concerning rearing, family, adult, and working environment, health status, health related behaviors (e.g. alcohol, tobacco, and dietary habits) as well as relationships, and personality measures. The questionnaires were sent again at 3 year intervals in 1987, 1990, 1993 and after a break again in 2004, 2007, and 2010. Thus far more than 2,000 twins have responded to at least one of the seven questionnaire assessments conducted between 1984 and 2010. Additionally there is information about midlife life style factors from the Swedish Twin Registry that were collected about twenty years before SATSA started. In the second component a subsample of 861 individuals have participated in at least one wave of in-person testing (IPT). The first IPT started in 1986 and since then eight IPTs have been collected and the last wave will be collected during 2012-2013. The IPT includes a health examination, structured interviews, tests of functional capacity, and memory and thinking abilities. To date, over 76% of the sample has participated in 3 or more measurement waves. At IPT9 a third component was added to SATSA, a measure of day-to-day fluctuations in memory and thinking abilities, and emotions. Information about social interactions is also collected. After the visit by the research nurses the twins fill out the day-to-day booklet during the next five days. This procedure will be repeated in IPT10. This will add information about small and short-term changes and more changes are supposed to indicate the beginning of poor health. Data from SATSA can be used to study various aspects of aging. For example, the relative importance of genetic and environmental factors for individual differences in aging especially in cognitive and physical domains has been studied. A further main focus is to study changes within and across domains and which genetic and life style factors predict these changes. Given the wide spectrum of data from measured genes to social relationships collected over more than two decades they dare to say that SATSA is a unique study, with the possibility to answer many questions within gerontology and geriatrics. Types of samples * Serum * DNA Number of sample donors: 674 (June 2010)gene, environment, health, disease, longitudinal, questionnaire, life style, interview, functional capacity, memory, thinking, emotion, social interaction, cognitive, physical, behavior, relationship, personality, healthSCR_005966(KI Biobank - SATSA, RRID:SCR_005966)Karolisnka Biobank Aging, Twin, Control, (reared apart vs. reared together)MacArthur Foundation Research Network on Successful Aging, NIA, Swedish Council for Working Life and Social Research, Swedish Research Councilrelated to: KI Biobank - HARMONY, uses: Swedish Twin Registry, listed by: One Mind Biospecimen Bank ListingLast checked downnlx_151325http://ki.se/forskning/ki-biobank, http://ki.se/ki/jsp/polopoly.jsp?d=29354&a=24035&l=en
KI Biobank - STAGEResource, disease-related portal, topical portal, research forum portal, biomaterial supply resource, data set, portal, material resource, data or information resourceTHIS RESOURCE IS NO LONGER IN SERVCE, documented September 2, 2016. The Swedish twin registry has recently examined all twins in Sweden born between 1959-1985. 25,000 individuals participated in the study. The twins had to implement a Web-based survey on the Internet or a telephone interview where we had to answer questions about, among other things, about the diseases they have, or have had, behaviors, eating and drinking habits, smoking habits, etc. The aim of the study is to extend the information in the Swedish twin registry. Our goal with twin studies are, inter alia, to study the relative importance of the heritage and environment for the emergence of various diseases. The responses from the study is currently the basis for a number of analyses regarding how inheritance and environment affects disease and tobacco habits. Currently third follow-up STAGE where 10,000 twins that had previously taken part are contacted again. The purpose of alteplase randomized controlled trials is to follow up the same individuals one year after the first and second questionnaire replies were received to see if anything has changed. The issues we are interested in the follow-up to include changes in general health, working and living situation, your weight, smoking habits, etc. Study Results The results we have so far come to and which we can present here are figures on the prevalence of certain diseases. The figures give a rough estimate of the incidence of these diseases will look for all individuals, born in Sweden in 1959-1985. The figures are based on the questions on the questionnaire which the twins themselves had to answer whether they have or have had various diseases.adult, gene, environment, survey, interview, disease, behavior, eating habit, drinking habit, questionnaire, nicotine, smoking, nicotine use disorderSCR_006004(KI Biobank - STAGE, RRID:SCR_006004)Karolisnka Biobank Twinrelated to: Swedish Twin Registry, listed by: One Mind Biospecimen Bank ListingLast checked downnlx_151384
BayGenomicsResource, biomaterial supply resource, material resource, organism supplier, tissue bankTHIS RESOURCE IS NO LONGER IN SERVICE, documented August 29, 2016. The BayGenomics gene-trap resource provides researchers with access to thousands of mouse embryonic stem (ES) cell lines harboring characterized insertional mutations in both known and novel genes. The major goal of BayGenomics is to identify genes relevant to cardiovascular and pulmonary disease.embryonic, expression, gene, bioinformatic, cardiopulmonary, cell, clone, disease, genomic, germline, insertional, line, mouse, mutant, mutation, pulmonary, stem, cardiovascular, pulmonary diseaseSCR_008168(BayGenomics, RRID:SCR_008168)University of California at San Francisco; California; USA listed by: One Mind Biospecimen Bank ListingLast checked downnif-0000-21042
Rutgers Cell and DNA RepositoryResource, biomaterial supply resource, data or information resource, material resource, cell repositoryRUCDR is a biobank and a service organization that maintains human blood, serum, saliva, tissue and the genetic products derived from those. Services include technical consultation and logistical support for biobanking. Researchers can order biomaterials and apply for phenotypic / genotypic data.genetics, disease, phenotypic data, genotypic data, cell, dna, blood, cell lineSCR_010624(Rutgers Cell and DNA Repository, RRID:SCR_010624)Rutgers University; New Jersey; USA related to: NIMH Center for Collaborative Genetic Studies on Mental Disorders, listed by: One Mind Biospecimen Bank ListingLast checked upnlx_60990
Lifelines BiobankResource, biomaterial supply resource, data or information resource, material resource, databaseOverall aim of the LifeLines Study is to unravel the interaction between genetic and environmental factors in the development of multifactorial diseases, their concurrent development in individuals and their complications as a complex trait. The LifeLines database contains questionnaire data, physical measurements and biological samples from different health examinations. Collaboration is encouraged as it helps to maximize the scientific value of the wealth of epidemiologic data made possible by the participation of more than 165,000 individuals in the LifeLines Cohort Study. Primary objectives of the LifeLines Cohort Study are: a. Which are the disease overriding risk factors which predict the development of a multifactorial disease during lifetime? b. How are these universal risk factors modified, or what determines the effect of a universal risk factor in an individual? Specific research questions will focus on risk factors and modifiers (genetic, environmental and combined or complex factors) for single and multiple diseases. In addition to co-morbidity, LifeLines focuses on co-determinants. The primary endpoints include measures of aging, metabolic and endocrine diseases, cardiovascular and renal diseases, pulmonary and musculoskeletal diseases, and psychopathology. Secondary aims include the assessment of the prevalence and incidence of multifactorial diseases, their risk factors and their treatment in individuals as well as in families. The burden of disease for the society will be quantified in terms of care needed, and total costs of care. Until November 3, 2011, almost 68,000 subjects have been included in the study. The 60,000th participant was screened in the beginning of September 2011. Recruitment rate at present is between 700 and 800 subjects per week. The laboratory measurements which are performed has changed. As of October 2011, LifeLines will continue to measure: hematologic parameters, including hemoglobin, white blood cells, platelets, WBC differentiation, blood glucose, cholesterol, HDL-cholesterol, triglycerides, serum creatinin and sodium/potassium. Liver enzymes, thyroid hormones, calcium, phosphate, albumin, uric acid and microalbuminuria will not be measured routinely. The samples that are available for almost all participants, are: # serum (taken either with or without gel separator) # EDTA plasma # citrate plasma # DNA # early morning urine sample # urine samples of 24-hour urine collection Any researcher who is member of an internationally recognized academic institution and who is interested in utilizing the research possibilities, data and materials of LifeLines may apply for access. The applicant who is acting as Principal Investigator must be connected to a department or institution with the competence to carry out the research project to term. A contract will give the right to use the data for a pre-determined period of time. This contract also comprises the costs for the LifeLines Biobank which the investigator needs to reimburse. To apply for access, refer to the electronic application process.blood, urine, plasma, serum, dna, edta plasma, citrate plasma, general population, clinical data, epidemiologic data, genetic factor, environmental factor, complex factor, multifactorial disease, risk factor, metabolic disease, endocrine disease, cardiovascular disease, renal disease, pulmonary disease, musculoskeletal disease, psychopathology, disease, nutrition, lifestyle, genetic epidemiologySCR_010730(Lifelines Biobank, RRID:SCR_010730)General population, Aginglisted by: One Mind Biospecimen Bank ListingLast checked upnlx_93394
Rat Resource and Research CenterResource, organism supplier, biomaterial supply resource, biospecimen repository, tissue bank, service resource, storage service resource, cell repository, material resource, material storage repositoryCenter that supplies biomedical investigators with the rat models, embryonic stem cells, related reagents, and protocols they require for their research. In addition to repository, cryostorage and distribution functions, RRRC can facilitate acquisition of rat strains from other international repositories as well as provide consultation and technical training to investigators using rat models.embryo, gamete, animal, drug, biomedical, cryopreserved, disease, genome, genotyping, germplasma, human, hybrid, inbred, infectious, molecular, mutant, nuclear, ovarian, pathogen, rat, research, tissue, rat model, embryonic stem cell, reagent, protocol, cell line, stem cell, strain, database, catalogSCR_002044(Rat Resource and Research Center, RRID:SCR_002044)University of Missouri; Missouri; USA NCRR, NIH Office of the Directorrelated to: One Mind Biospecimen Bank Listing, Monarch Initiative, listed by: One Mind Biospecimen Bank ListingLast checked upnif-0000-12085http://www.nrrrc.missouri.edu/
HipSciResource, production service resource, biomaterial supply resource, material service resource, data set, service resource, cell repository, material resource, biomaterial manufacture, data or information resourceA UK national induced pluripotent stem (iPS) cell resource that will create and characterize more than 1000 human iPSCs from healthy and diseased tissue for use in cellular genetic studies. Between 2013 and 2016 they aim to generate iPS cells from over 500 healthy individuals and 500 individuals with genetic disease. They will then use these cells to discover how genomic variation impacts on cellular phenotype and identify new disease mechanisms. Strong links with NHS investigators will ensure that studies on the disease-associated cell lines will be linked to extensive clinical information. Further key features of the project are an open access model of data sharing; engagement of the wider clinical genetics community in selecting patient samples; and provision of dedicated laboratory space for collaborative cell phenotyping and differentiation.stem cell, genomic variation, cellular phenotype, disease mechanism, phenotype, disease, clinical data, clinical, genetics, male, female, cell line, induced pluripotent stem cellSCR_003909(HipSci, RRID:SCR_003909)European Bioinformatics Institute Healthy, Genetic diseaseMRC, Wellcome Trustlisted by: One Mind Biospecimen Bank ListingLast checked upnlx_158252
Biobank GrazResource, production service resource, analysis service resource, biomaterial supply resource, tissue bank, service resource, material resource, data or information resourceBiobank Graz is a non-profit central Medical University of Graz (MUG) service facility that provides the logistics and infrastructure to optimally support MUG research teams in the collection, processing and storage of biological samples and their associated data. In the course of this, special attention is given to sample and data quality and to the protection of the individual rights of patients. Samples from selected patients at the Graz LKH-University Clinical Centre, who have signed an informed consent declaration, are deposited in Biobank Graz. This means that excess tissue and blood samples are collected and placed in storage. The samples are harvested in the course of routine interventions undertaken by the different departments and institutes of the Graz LKH-University Clinical Centre and approved for use in research projects only after the completion of all necessary laboratory and histopathological analyses. No additional material is removed: in other words, there are no associated drawbacks whatsoever for the patients involved. Biobank Graz operates a quality management system according to ISO 9001:2008 and offers the following services for the processing and storage of biological samples and the handling of data: * Consistently high sample quality through the processing of samples using standardized methods in accordance with written working instructions (SOPs) * Efficient use of resources through the building of shared infrastructure and the development of optimized processes * A high degree of reliability provided by the storage of samples in 24/7 - monitored storage systems. * Processing and storage of all data in accordance with data protection legislation. Biobank Graz comprises both population-based and disease-focused collections of biological materials. It currently contains approx. 3.8 mio samples from approx. 1.2 mio patients representing a nonselected patient group characteristic of central Europe. Because the Institute of Pathology was, until 2003, the exclusive pathology service provider for major parts of the province of Styria, including its capital Graz (population approx. 1.2 mio people), samples from all human diseases, treated by surgery or diagnosed by biopsy, are included in the collection at their natural frequency of occurrence and thus represent cancers and non-cancerous diseases from all organs, and from all age groups. The scientific value of the existing tissue collection is, thus, not only determined by its size and technical homogeneity (all samples have been processed in a single institute under constant conditions for more than 20 years), but also by its population-based character. These features provide ideal opportunities for epidemiological studies and allow the validation of biomarkers for the identification of specific diseases and determination of their response to treatment. Prospectively collected tissues, blood samples and clinical data comprise, on the one hand, randomly selected samples from all diseases and patient groups to provide sufficient numbers of samples for the evaluation of the disease-specificity of any gene or biomarker. On the other hand, Biobank Graz adopts a disease-focused approach for selected diseases (such as breast, colon and liver cancers as well as some metabolic diseases) through the collection of a range of different human biological samples of highest quality and detailed clinical follow-up data. Graz Medical University established the Biobank to provide improved and sustainable access to biological samples and related (clinical) data both for its own academic research and for external research projects of academic and industrial partners. It is a major interest of the university to initiate co-operative research projects. Biological samples and data are available to external institutions performing high-quality research projects which comply with the Biobank''s ethical and legal framework according to the access rules (Contact: COO Karine Sargsyan, MD, PhD).tissue, blood, dna, rna, serum, plasma, bodily fluid, urine, cryopreserved, formalin fixed paraffin embedded, csf, frozen, disease, population, patient, healthy, normal, clinical, patient, healthy, normal, disease, cancer, metabolic disease, breast cancer, colon cancer, liver cancer, clinical data, cerebral spinal fluidSCR_004245(Biobank Graz, RRID:SCR_004245)Medical University of Graz; Graz; Austria All, Patient, Healthy, Normal, Disease, Cancer, Metabolic disease, Breast cancer, Colon cancer, Liver cancerlisted by: One Mind Biospecimen Bank ListingLast checked upnlx_25894
Marshfield Clinic BiobankResource, biomaterial supply resource, data or information resource, material resource, databaseA large collection of biological samples and health information collected for the Personalized Medicine Research Project (PMRP) for use in biological research. Genetic information from 20,000 participants forms a database enabling scientists to study which genes cause disease, which genes predict reactions to drugs, and how environment and genes work together to cause disease. The goal of this project is to learn how to apply genetic science to human health. This knowledge will help researchers develop new medications and diagnostic tests, and will enable physicians to prescribe medications that work best for a particular person. Marshfield Clinic Personalized Medicine Research Project (PMRP) resources currently available: DNA, plasma, serum, questionnaire, electronic medical records to construct phenotypes; ability to recontact subjects for additional information (where they have given consent for recontact); stored pathology specimens collected for clinical purposes; 51 clinically relevant polymorphisms; Illumina 660 quad for ~4200 subjects aged 50+.dna, adult human, blood, disease, gene, environment, questionnaire, electronic medical record, clinical, plasma, serum, drug, personalized medicineSCR_004368(Marshfield Clinic Biobank, RRID:SCR_004368)listed by: One Mind Biospecimen Bank ListingLast checked upnlx_38684http://www.marshfieldclinic.org/chg/pages/default.aspx?page=chg_pers_med_res_prj
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