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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

(last updated: Oct 12, 2019)

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Resource NameResource TypeDescriptionKeywordsResource IDProper CitationParent OrganizationRelated ConditionFunding AgencyRelationReferenceWebsite StatusAlternate IDsAlternate URLsOld URLs
Geisinger BiobankResource, biomaterial supply resource, material resource, data or information resourceBy collecting and analyzing blood samples from Geisinger''s large patient population, MyCode will help unlock the mysteries of some of the most devastating and debilitating diseases. Blood samples are obtained from patients of certain Geisinger specialty clinics to study specific conditions, such as obesity and cardiovascular disease, and also from patients of Geisinger primary care clinics to provide a representative sample of the regional population. More than 60,000 samples from over 23,000 Geisinger patients have been collected so far, and sample collection is ongoing. MyCode researchers use the blood samples to study the genetic causes of diseases and certain disease-related molecular mediators. Knowledge gained from these studies will allow researchers to pursue innovative approaches to disease prevention, diagnosis and treatment. To be of value for Genomic Medicine research, bio-banked samples must be connected to clinical data: MyCode allows genetic and molecular data about the samples to be connected to medical data in a way that protects patient identity. When a patient agrees to participate in MyCode, blood samples for the MyCode Project are collected during blood draws ordered as part of the patient''s routine medical care. After the sample is drawn and labeled, a staff member from the Weis Center for Research transports the blood to the Geisinger Clinic Genomics Core (GCGC) where it is processed for storage. At this stage, all personal identification markers are removed and the samples are assigned a randomly-selected identification number. A secure key is maintained that allows approved researchers to connect the samples to the clinical data for genomic studies in a way that ensures confidentiality of the information. To maintain confidentiality of MyCode data the code linking the research numbers and the electronic health records are kept in a password-protected files accessible only to MyCode team members. Additionally, all results generated from the samples are reported as a group so that individuals are not identified. The samples are stored indefinitely.gene, genetics, disease, clinical data, genomic medicine, genetic data, molecular data, blood, obesity, cardiovascular disease, other specific conditions, regional populationSCR_005652(Geisinger Biobank, RRID:SCR_005652)Obesity, Cardiovascular disease, Disease, Other conditions, Regional populationBen Franklin Technology Development Authority, Geisinger Clinic Administrative Committee for Researchlisted by: One Mind Biospecimen Bank ListingLast checked downnlx_14718
Nuclear Receptor Signaling Atlas Resource, database, service resource, storage service resource, atlas, knowledge environment, data repository, material resource, reagent supplier, data or information resourceSoftware tool as knowledge environment resource that accrues, develops, and communicates information that advances understanding of structure, function, and role in disease of nuclear receptors (NRs) and coregulators. It specifically seeks to elucidate roles played by NRs and coregulators in metabolism and development of metabolic disorders. Includes large validated data sets, access to reagents, new findings, library of annotated prior publications in field, and journal covering reviews and techniques.nuclear receptor, coregulator, metabolism, metabolic disorder, type 2 diabetes, obesity, osteoporosis, lipid dysregulation, cardiovascular disease, oncology, regenerative medicine, environmental agent, genomics, proteomics, reagent, ligand, microarray, gene expression, data set, data analysis service, nuclear receptor signaling, signaling, high through put screening, receptor, ligand, journal, molecule, affinity purification, q-pcr, chip-chip, animal model, antibody, cell line, primer, transcriptomine, clinical trial, disease, drug, data setSCR_003287( Nuclear Receptor Signaling Atlas , RRID:SCR_003287)Baylor College of Medicine; Houston; Texas Metabolic disorder, Type 2 diabetes mellitus, Obesity, Osteoporosis, Lipid dysregulation, Cardiovascular disease, Diabetes, CancerNHLBI, NICHD, NIDDK, NIEHSrelated to: dkCOIN , Integrated Manually Extracted Annotation, used by: NIF Data Federation, NIDDK Information Network, recommended by: National Library of Medicine, BRAIN Initiative, listed by: NIH Data Sharing Repositories, NIDDK Research Resources, NIDDK Information Network, lists: NURSA Transcriptomine, STRING, Nuclear Receptor CistromeDOI:10.1101/401729Last checked upnif-0000-03208
Social Environment and Biomarkers of Aging Study in TaiwanResource, data set, data or information resourceData sets of information regarding the health and well-being of older persons in Taiwan (from 2000 and 2006), in particular the relationship between life challenges and mental and physical health, the impact of social environment on the health and well-being of the elderly, and biological markers of health and stress. The study collected self-reports of physical, psychological, and social well-being, plus extensive clinical data based on medical examinations and laboratory analyses. Examination of health outcomes included chronic illnesses, functional status, psychological well-being, and cognitive function. Questions regarding life challenges focused on perceived stress, economic difficulties, security and safety, and the consequences of a major earthquake. Biological markers were used to identify cardiovascular risk factors, metabolic process measures, immune-system activity, the hypothalamic-pituitary adrenal axis, and sympathetic nervous system activity. The study design consists of face-to-face interviews with participants drawn from a random sub-sample of participants from 27 PSUs from the 1999 Survey of Health and Living Status of the Middle Aged and Elderly in Taiwan. Hospital visits and blood and urine specimens also were collected. A second wave of SEBAS was conducted in 2006 using a similar protocol to SEBAS 2000, but with the addition of performance assessments conducted by the interviewers at the end of the home interview. * Dates of Study: -2000, 2006 * Study Features: Longitudinal, International, Anthropometric Measures * Sample Size: 27 PSUslate adult human, middle adult human, longitudinal, international, anthropometric measure, health, well-being, taiwan, biomarker, cognitive functioning, diet, disease, health behavior, health status, illness, leisure, life event, life satisfaction, medical evaluation, medical history, medication, mental health, physical condition, physical limitation, psychological well-being, social environment, stress, urinalysis, clinical, interview, metabolic process, immune-system, hypothalamic-pituitary adrenal, sympathetic nervous system, blood, urineSCR_003704(Social Environment and Biomarkers of Aging Study in Taiwan, RRID:SCR_003704)Georgetown University; Washington D.C.; USA Aging, Cardiovascular diseaseBureau of Health Promotion National Health Research Institute Taiwan, NIA, Taiwan Department of Health, Taiwan Provincial Governmentlisted by: National Archive of Computerized Data on Aging (NACDA), Inter-university Consortium for Political and Social Research (ICPSR)Last checked upnlx_157859,
National Genome Research NetworkResource, organization portal, portal, data or information resourceThe program of medical genome research is a large-scale biomedical research project which extends the national genome research net (NGFN) and will be funded by the federal ministry of education and research (BMBF) from 2008-2013. Currently the program includes two fields: * Research ** NGFN-Plus: With the aim on combating diseases that are central to health policy, several hundred researchers are systematically investigating the complex molecular interactions of the human body. They are organized in 26 Integrated Genome Research Networks. * Application ** NGFN-Transfer: The rapid transfer of results from medical genome research into medical and industrial application is the aim of the scientists from research institutes and biomedical enterprises that cooperate in eight Innovation Alliances. AREAS OF DISEASE * Cardiovascular disease * Cancer * Neuronal diseases * Infections and Inflammations * Environmental factorsgenome, research, gene, diseaseSCR_006626(National Genome Research Network, RRID:SCR_006626)Cardiovascular disease, Cancer, Neuronal disease, Infectious disease, Inflammation, Disease linked to environmentBMBFLast checked upnlx_151595
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