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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

(last updated: Oct 12, 2019)

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Resource NameResource TypeDescriptionKeywordsResource IDProper CitationParent OrganizationRelated ConditionFunding AgencyRelationReferenceWebsite StatusAlternate IDsAlternate URLsOld URLs
CKID A Prospective Cohort Study of Kidney Disease in Children Resource, disease-related portal, topical portal, resource, research forum portal, portal, bibliography, data or information resourceProspective, observational cohort study of children with mild to moderate chronic kidney disease (CKD) to: (1) determine risk factors for progression of pediatric chronic kidney disease (CKD); (2) examine the impact of CKD on neurocognitive development; (3) examine the impact of CKD on risk factors for cardiovascular disease, and; (4) examine the impact of CKD on growth. The CKiD study population will include a cohort of 540 children, age 1 16 years, expected to be enrolled over a 24-month period.child, young human, pediatric, risk factor, kidney function, neurodevelopment, cognitive ability, behavior, kidney, urologic problem, glomerular disease, adverse effect, cognition, growth, adolescent, infant, clinicalSCR_001500( CKID A Prospective Cohort Study of Kidney Disease in Children , RRID:SCR_001500)Johns Hopkins University; Maryland; USA Chronic kidney disease, Renal disease, Cardiovascular diseaseNCRR, NIDDKlisted by: NIDDK Information Network, submitted by: NIDDK Information NetworkLast checked downnlx_152790
NephromineResource, data or information resource, databaseA growing database of publicly available renal gene expression profiles, a sophisticated analysis engine, and a powerful web application designed for data mining and visualization of gene expression. It provides unique access to datasets from the Personalized Molecular Nephrology Research Laboratory incorporating clinical data which is often difficult to collect from public sources and mouse data.kidney, gene expression, visualization, clinical, expression profile, gene, mouse model, microarraySCR_003813(Nephromine, RRID:SCR_003813) Life Technologies , University of Michigan; Michigan; USA Kidney disease, Healthy, Lupus nephritis, Chronic kidney disease, Diabetic nephropathylisted by: NIDDK Information NetworkLast checked upnlx_158114
DaVitaResource, disease-related portal, topical portal, commercial organization, service resource, portal, data or information resourceCommercial dialysis provider with offerings that include in-center hemodialysis, in-center nocturnal dialysis, peritoneal dialysis, home hemodialysis, vascular access management, chronic kidney disease education, and renal diet assistance. (Adapted from Wikipedia) Information on dialysis and chronic kidney disease, including informative articles and animated learning modules, and recipes for the dialysis diet are also available. Take advantage of their discussion forum, Find a Dialysis Center tool, DaVita GFR Calculator and more.dialysis, health care, kidney, diet, clinical, administrative serviceSCR_003980(DaVita, RRID:SCR_003980)Chronic kidney disease, End stage renal diseaserelated to: Kidney Health InitiativeLast checked upnlx_158385
FAST BioMedicalResource, portal, organization portal, commercial organization, data or information resourceA clinical stage company developing a timely, precise, and convenient method for measuring plasma volume and glomerular filtration rate (GFR). They focus on development and commercialization of a patented technology for quantifying clinically relevant parameters that have been challenging or impossible to measure in the past. The company is currently developing technology for quantifying volume status and kidney function in a clinically actionable timeframe. Their technology could have a significant impact on the treatment of patients with acute kidney injury (AKI) and chronic kidney disease (CKD).clinical, kidney function, plasma volume, glomerular filtration rate, kidneySCR_003983(FAST BioMedical, RRID:SCR_003983)Acute kidney injury, Chronic kidney diseaserelated to: Kidney Health InitiativeLast checked upnlx_158390
Thrasos TherapeuticsResource, portal, organization portal, commercial organization, data or information resourceA private, clinical-stage biotherapeutics company focused on delivering new solutions to individuals affected by kidney disease. They are committed to developing novel approaches to protect, treat and restore kidney function for this patient group. The company has designed a specific class of peptide compounds that have shown excellent results in controlling experimental kidney diseases, notably, models of diabetic nephropathy (kidney damage associated with diabetes), and acute kidney injury. These proprietary peptides may therefore be able to prevent and treat acute kidney injury, as well as slow and possibly reverse the progression of diabetic nephropathy. They act to control apoptosis (programmed cell death), inflammation and fibrosis (formation of scar tissue).biotherapeutics, clinical, peptideSCR_004052(Thrasos Therapeutics, RRID:SCR_004052)Kidney disease, Acute kidney injury, Diabetic nephropathy, Chronic kidney diseaserelated to: Kidney Health InitiativeLast checked upnlx_158489
Creatinine Standardization Program Resource, resource, international standard specification, standard specification, narrative resource, experimental protocol, data or information resourceStandard specification to reduce inter-laboratory variation in creatinine assay calibration and therefore enable more accurate estimates of glomerular filtration rate (eGFR). Created by NKDEP''''s Laboratory Working Group in collaboration with the International Federation of Clinical Chemistry and Laboratory Medicine (IFCC) and the European Communities Confederation of Clinical Chemistry (now called the European Federation of Clinical Chemistry and Laboratory Medicine), the effort is part of a larger NKDEP initiative to help health care providers better identify and treat chronic kidney disease in order to prevent or delay kidney failure and improve patient outcomes. Recommendations are intended for the USA and other countries or regions that have largely completed standardization of creatinine calibration to be traceable to an isotope dilution mass spectrometry (IDMS) reference measurement procedure. The program''''s focus is to facilitate the sharing of information to assist in vitro diagnostic manufacturers, clinical laboratories, and others in the laboratory community with calibrating their serum creatinine measurement procedures to be traceable to isotope dilution mass spectrometry (IDMS). The program also supports manufacturers'''' efforts to encourage their customers in the laboratory to coordinate use of standardized creatinine methods with implementation of a revised GFR estimating equation appropriate for use with standardized creatinine methods. Communication resources and other information for various segments of the laboratory community are available in the Creatinine Standardization Recommendations section of the website. Also available is a protocol for calibrating creatinine measurements using whole blood devices. The National Institute for Standards and Technology (NIST) released a standard reference material (SRM 967 Creatinine in Frozen Human Serum) for use in establishing calibrations for routine creatinine measurement procedures. SRM 967 was validated to be commutable with native serum samples for many routine creatinine procedures and is useful to establish or verify traceability to an IDMS reference measurement procedure. Establishing calibrations for serum creatinine methods using SRM 967 not only provides a mechanism for ensuring more accurate measurement of serum creatinine, but also enables more accurate estimates of GFR. For clinical laboratories interested in independently checking the calibration supplied by their creatinine reagent suppliers/manufacturers, periodic measurement of NIST SRM 967 should be considered for inclusion in the lab''''s internal quality assurance program. To learn more about SRM 967, including how to purchase it, visit the NIST website, https://www-s.nist.gov/srmors/quickSearch.cfmcreatinine, estimate, glomerular filtration rate, kidney, isotope dilution mass spectrometry, whole blood, calibration, serum, serum creatinine, clinicalSCR_006441( Creatinine Standardization Program , RRID:SCR_006441) National Kidney Disease Education Program Chronic kidney diseaseNIDDKrelated to: Glomerular Filtration Rate Calculators , NIDDK Information Network, NIST - National Institute of Standards and Technology, submitted by: NIDDK Information NetworkLast checked upnlx_152736
Chronic Renal Insufficiency Cohort Study Resource, disease-related portal, topical portal, resource, research forum portal, biomaterial supply resource, portal, material resource, data or information resourceA prospective observational national cohort study poised to make fundamental insights into the epidemiology, management, and outcomes of chronic kidney disease (CKD) in adults with intended long-term follow up. The major goals of the CRIC Study are to answer two important questions: * Why does kidney disease get worse in some people, but not in others? * Why do persons with kidney disease commonly experience heart disease and stroke? The CRIC Scientific and Data Coordinating Center at Penn receives data and provides ongoing support for a number of Ancillary Studies approved by the CRIC Cohort utilizing both data collected about CRIC study participants as well as their biological samples. The CRIC Study has enrolled over 3900 men and women with CKD from 13 recruitment sites throughout the country. Following this group of individuals over the past 10 years has contributed to the knowledge of kidney disease, its treatment, and preventing its complications. The NIDDKwill be extending the study for an additional 5 years, through 2018. An extensive set of study data is collected from CRIC Study participants. With varying frequency, data are collected in the domains of medical history, physical measures, psychometrics and behaviors, biomarkers, genomics/metabolomics, as well as renal, cardiovascular and other outcomes. Measurements include creatinine clearance and iothalamate measured glomerular filtration rate. Cardiovascular measures include blood pressure, ECG, ABI, ECHO, and EBCT. Clinical CV outcomes include MI, ischemic heart disease-related death, acute coronary syndromes, congestive heart failure, cerebrovascular disease, peripheral vascular disease, and composite outcomes. The CRIC Study has delivered in excess of 150,000 bio-samples and a dataset characterizing all 3939 CRIC participants at the time of study entry to the NIDDKnational repository. The CRIC Study will also be delivering a dataset to NCBI''''s Database for Genotypes and Phenotypes.clinical, epidemiology, management, outcome, adult human, medical history, physical measure, psychometrics, behavior, renal, biomarker, genomics, gwas, kidney, data sharing, bibliography, observational cohort study, male, female, cardiovascular, heart, kidney, risk factor, metabolomicsSCR_009016( Chronic Renal Insufficiency Cohort Study , RRID:SCR_009016)University of Pennsylvania Perelman School of Medicine; Pennsylvania; USA Chronic kidney disease, Cardiovascular diseaseNIDDKrelated to: NCBI database of Genotypes and Phenotypes, NIDDK Central Repository, AASK Clinical Trial and Cohort Study, listed by: One Mind Biospecimen Bank Listing, NIDDK Information Network, NIDDK Research Resources, Diabetes Research Centers, submitted by: NIDDK Information NetworkLast checked upnlx_152758
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