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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

(last updated: Oct 12, 2019)

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Resource NameResource TypeDescriptionKeywordsResource IDProper CitationParent OrganizationRelated ConditionFunding AgencyRelationReferenceWebsite StatusAlternate IDsAlternate URLsOld URLs
International HapMap ProjectResource, narrative resource, data or information resource, experimental protocol, databaseTHIS RESOURCE IS NO LONGER IN SERVICE, documented August 22, 2016. A multi-country collaboration among scientists and funding agencies to develop a public resource where genetic similarities and differences in human beings are identified and catalogued. Using this information, researchers will be able to find genes that affect health, disease, and individual responses to medications and environmental factors. All of the information generated by the Project will be released into the public domain. Their goal is to compare the genetic sequences of different individuals to identify chromosomal regions where genetic variants are shared. Public and private organizations in six countries are participating in the International HapMap Project. Data generated by the Project can be downloaded with minimal constraints. HapMap project related data, software, and documentation include: bulk data on genotypes, frequencies, LD data, phasing data, allocated SNPs, recombination rates and hotspots, SNP assays, Perlegen amplicons, raw data, inferred genotypes, and mitochondrial and chrY haplogroups; Generic Genome Browser software; protocols and information on assay design, genotyping and other protocols used in the project; and documentation of samples/individuals and the XML format used in the project.genetic variant, disease, genetic sequence, genetic variation, single nucleotide polymorphism, genetic diversity, dna, sequence, catalog, genome, chromosomeSCR_002846(International HapMap Project, RRID:SCR_002846)NCBI Chinese Academy of Sciences, Chinese Ministry of Science and Technology, Delores Dore Eccles Foundation, Genome Canada, Genome Quebec, Hong Kong Innovation and Technology Commission, Japanese Ministry of Education Culture Sports Science and Technology MEXT, National Natural Science Foundation of China, NIH, SNP Consortium, University Grants Committee of Hong Kong, Wellcome Trust, W. M. Keck Foundationrelated to: SNAP - SNP Annotation and Proxy Search, Haploview, NHGRI Sample Repository for Human Genetic Research, DistiLD - Diseases and Traits in LD, SNP at Ethnos, GBrowse, used by: BioSample Database at EBI, listed by: OMICtoolsLast checked downnif-0000-02940, OMICS_00273
Genes to Cognition: Neuroscience Research ProgrammeResource, blog, topical portal, software application, narrative resource, portal, software resource, training material, data or information resourceA neuroscience research program that studies genes, the brain and behavior in an integrated manner, established to elucidate the molecular mechanisms of learning and memory, and shed light on the pathogenesis of disorders of cognition. Central to G2C investigations is the NMDA receptor complex (NRC/MASC), that is found at the synapses in the central nervous system which constitute the functional connections between neurons. Changes in the receptor and associated components are thought to be in a large part responsible for the phenomenon of synaptic plasticity, that may underlie learning and memory. G2C is addressing the function of synapse proteins using large scale approaches combining genomics, proteomics and genetic methods with electrophysiological and behavioral studies. This is incorporated with computational models of the organization of molecular networks at the synapse. These combined approaches provide a powerful and unique opportunity to understand the mechanisms of disease genes in behavior and brain pathology as well as provide fundamental insights into the complexity of the human brain. Additionally, Genes to Cognition makes available its biological resources, including gene-targeting vectors, ES cell lines, antibodies, and transgenic mice, generated for its phenotyping pipeline. The resources are freely-available to interested researchers.electrophysiological, es cell, functional, gene, gene-target vector, genetic, 1295s, allele, antibody, behavior, behavioral, brain, c57bl/6j, central nervous system, clone, cognition, computation, connection, deletion, disease, disorder, dlg3, dlg4, domain, genomic, guanylate kinase, hprt gene, hras1, human, knockout, learning, mechanism, memory, model, molecular, mouse, mutation, network, neuron, neuroscience, nmda receptor complex, pathogenesis, phenotyping, protein, proteomics, ptk2, strain, synapse, synaptic plasticity, syngap1, transgenic, modelSCR_007121(Genes to Cognition: Neuroscience Research Programme, RRID:SCR_007121)Wellcome Trust Sanger Institute; Hinxton; United Kingdom BBSRC, EPSRC, European Union, Framework Programme, Gatsby Charitable Foundation, Human Frontiers Science Programme, MRC, NSF, Wellcome Trustlisted by: 3DVCLast checked downnif-0000-10235
IUPHAR/BPS Guide to PharmacologyResource, narrative resource, data or information resource, portal, standard specification, databasePortal and searchable database of pharmacological information. Information is presented at two levels, the initial view or landing pages for each target family provide expert-curated overviews of the key properties and the available selective ligands and tool compounds. For selected targets, more detailed introductory chapters for each family are available along with curated information on the pharmacological, physiological, structural, genetic and pathophysiogical properties of each target.pharmacology, drug discovery, portal, guide, physiology, molecular structureSCR_013077(IUPHAR/BPS Guide to Pharmacology, RRID:SCR_013077)NC-IUPHAR Wellcome TrustPMID:21087994Last checked upnif-0000-03056
OME-TIFF FormatResource, narrative resource, standard specification, data or information resourceA standardized file format for multidimensional microscopy image data. OME-TIFF maximizes the respective strengths of OME-XML and TIFF. It takes advantage of the rich metadata defined in OME-XML while retaining the pixel structure in multi-page TIF format for compatibility with many image-processing applications. An OME-TIFF dataset has the following characteristics: * Image planes are stored within one multi-page TIFF file, or across multiple TIFF files. Any image organization is feasible. * A complete OME-XML metadata block describing the dataset is embedded in each TIFF file's header. Thus, even if some of the TIFF files in a dataset are misplaced, the metadata remains intact. * The OME-XML metadata block may contain anything allowed in a standard OME-XML file. * OME-TIFF uses the standard TIFF mechanism for storing one or more image planes in each of the constituent files, instead of encoding pixels as base64 chunks within the XML. Since TIFF is an image format, it makes sense to only use OME-TIFF as opposed to OME-XML, when there is at least one image plane.microscopy, format, archiving, data management, annotation, mark up, metadata standard, standard, tiff, ome-xmlSCR_002636(OME-TIFF Format, RRID:SCR_002636)OME - Open Microscopy Environment Wellcome Trustrelated to: JCB DataViewer, Cell Image Library (CIL), HMS LINCS Database, Stowers Original Data Repository, Bio-Formats, listed by: FORCE11PMID:15892875Last checked upnlx_156061
ISRCTN RegistryResource, international standard specification, narrative resource, data or information resource, standard specification, databaseA primary clinical trial registry which houses proposed, ongoing, and completed clinical research studies. An ISRCTN is a simple numeric system for the unique identification of randomized controlled trials worldwide. The registry provides content validation and curation and the unique identification number necessary for publication. Submitted studies range from cancer to urological diseases.clinical trial, unique identifier, observational trial, interventional trial, health, registry, clinical, trialSCR_006087(ISRCTN Registry, RRID:SCR_006087)Current Controlled Trials Canadian Institutes of Health Research, Department of Health UK, Medical Research Council, Wellcome Trustrelated to: Current Controlled Trials, used by: Current Controlled TrialsLast checked upnlx_151501
CellMLResource, narrative resource, interchange format, markup language, standard specification, data or information resourceThe CellML language is an open standard based on the XML markup language. The purpose of CellML is to store and exchange computer-based mathematical models. CellML allows scientists to share models even if they are using different model-building software. It also enables them to reuse components from one model in another, thus accelerating model building. Although CellML was originally intended for the description of biological models; CellML includes information about model structure (how the parts of a model are organizationally related to one another), mathematics (equations describing the underlying processes) and metadata (additional information about the model that allows scientists to search for specific models or model components in a database or other repository). The CellML team is committed to providing freely available tools for creating, editing, and using CellML models. We provide information regarding tools we are developing internally and links to external projects developing tools which utilize the CellML format. Please let us know if you have an open source CellML tool looking for a home on the internet, as we are able to offer limited hosting services on model, cell, mathematical model, mathematics, metadata, model structure, model, xml, annotation, mark up languageSCR_008061(CellML, RRID:SCR_008061)University of Auckland; Auckland; New Zealand aneurIST, Foundation for Research Science and Technology, International Union of Physiological Sciences: Physiome Project, Maurice Wilkins Centre for Molecular Biodiscovery, NZIMA, VPH NoE, Wellcome Trustrelated to: PathGuide: the pathway resource list, listed by: 3DVCReferences (7)Last checked upnif-0000-10448
ORCID - Open Researcher and Contributor IDResource, international standard specification, narrative resource, service resource, standard specification, data or information resourceNon-profit organization dedicated to solving the author/contributor name ambiguity problem in scholarly communications by creating a central registry of unique identifiers for individual researchers and an open and transparent linking mechanism between ORCID and other current author ID schemes. These identifiers, and the relationships among them, can be linked to the researcher''s output to enhance the scientific discovery process and to improve the efficiency of research funding and collaboration within the research community. The ideal solution is to establish a registry that is adopted and embraced as the de facto standard by the whole of the community. A resolution to the systemic name ambiguity problem, by means of assigning unique identifiers linkable to an individual''s research output, will enhance the scientific discovery process and improve the efficiency of funding and collaboration. The organization brings together the leaders of the most influential universities, funding organizations, societies, publishers and corporations from around the globe and is managed by a fourteen member Board of Directors. A disambiguated set of authors will allow new services and benefits to be built for the research community by all stakeholders in scholarly communication: from commercial actors to non-profit organizations, from governments to ambiguity, scholarly communication, unique identifier, author identification, identifier service, people resourceSCR_008700(ORCID - Open Researcher and Contributor ID, RRID:SCR_008700)American Chemical Society, American Institute of Physics, American Physical Society, Association for Computing Machinery, Elsevier, Hindawi, Microsoft Research, MIT Libraries, Nature Publishing Group, Oxford University Press, PLoS, Springer, Taylor and Francis Group, Thompson Reuters, Wellcome Trust, Wileyrelated to: Europe PubMed Central, Academic Karma, used by: Academic Karma, listed by: FORCE11Last checked upnif-0000-37710
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