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on page 1 showing 6 out of 6 results

Cite this ( Gregory Fleming James Cystic Fibrosis Research Center Assay Core , RRID:SCR_015407)

URL: https://www.uab.edu/medicine/cysticfibrosis/about/assay-core

Resource Type: Resource, service resource, resource, core facility, access service resource

Core that provides Ussing chamber capabilities and expertise for testing vectoral anion transport in polarized airway epithelial monolayers, and florescent dye-based methods for evaluating CFTR activity in cells grown on coverslips. The core also performs immunolocalization for proteins relevant to cystic fibrosis pathogenesis.

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Cite this ( Gregory Fleming James Cystic Fibrosis Research Center Cell Model and Evaluation Core , RRID:SCR_015395)

URL: https://www.uab.edu/medicine/cysticfibrosis/about/cell-model-core

Resource Type: Resource, service resource, resource, core facility, access service resource

Core that assists with patch clamp and single channel analysis relevant to ion channel gating. The core also provides primary murine airway epithelial cells.

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Cite this ( Gregory Fleming James Cystic Fibrosis Research Center Cystic Fibrosis Animal Models Core , RRID:SCR_015396)

URL: https://www.uab.edu/medicine/cysticfibrosis/about/animal-core

Resource Type: Resource, service resource, resource, core facility, access service resource

Core that assists in mouse line generation by both oocyte micro-injection and by embryonic stem cell gene targeting technologies. It also establishes breeding colonies of cystic fibrosis mice, and genotypes and provides these to UAB investigators and furnishes electrophysiology tests of CFTR activation, including murine nasal potential difference assays and intestinal short circuit current measurements.

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Cite this ( Gregory Fleming James Cystic Fibrosis Research Center Cystic Fibrosis Clinical and Translational Core , RRID:SCR_015399)

URL: https://www.uab.edu/medicine/cysticfibrosis/about/translational-core

Resource Type: Resource, service resource, resource, core facility, access service resource

Core that provides human primary nasal airway epithelial cells and bronchial airway epithelial cells, expertise in the nasal potential difference measurement, and a means to understand pathogenesis of cystic fibrosis and other metabolic diseases.

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Cite this ( Gregory Fleming James Cystic Fibrosis Research Center Cystic Fibrosis Transmembrane Conductance Regulator Expression Core , RRID:SCR_015397)

URL: https://www.uab.edu/medicine/cysticfibrosis/about/cftr-expression-core

Resource Type: Resource, service resource, resource, core facility, access service resource

Core that maintains a repository of reagents for studying CFTR and assists with expression technologies using vaccinia, adenovirus and other methodologies and antibody based detection of cystic fibrosis related gene products.

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Cite this ( Gregory Fleming James Cystic Fibrosis Research Center , RRID:SCR_015392)

URL: https://www.uab.edu/medicine/cysticfibrosis/

Resource Type: Resource, disease-related portal, topical portal, resource, service resource, portal, access service resource, data or information resource

Research center that maintains core facilities available for studies of cell biology, ion transport, and translational aspects of cystic fibrosis research.

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