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on page 1 showing 20 out of 22 results

Cite this (Alzheimers Disease Genetics Consortium, RRID:SCR_004004)

URL: http://www.adgenetics.org/

Resource Type: Resource, data set, organization portal, portal, consortium, data or information resource

Consortium to conduct genome-wide association studies (GWAS) to identify genes associated with an increased risk of developing late-onset Alzheimer''''s disease (LOAD). The goal of the ADGC is to identify genetic variants associated with risk for AD. It plans to do this through the following collaborative goals: # Identify genes responsible for AD susceptibility # Identify AD sub-phenotype genes rate-of-progression plaque / tangle load / distribution biomarker variability # Generate a genetic data resource for the AD research community Data generated by ADGC is available at the following website: https://www.niagads.org/content/alzheimers-disease-genetics-consortium-adgc-collection

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Cite this (Benchling, RRID:SCR_013955)

URL: https://benchling.com

Resource Type: Resource, software resource, service resource, computational hosting, web application

An online resource which helps researchers manage and organize labs and experimental results by supplying molecular biology software tools for experimental design and data analysis. Benchling provides tools for functions such as primer design and colony counting as well as CRISPR guide design and automated Gibson and Golden Gate cloning. Users can take notes in line with data, link data across entries, keep files and data in one place, and manage and keep track of team progress. An enterprise version of Benchling is available for scientists working within an organization with additional administrative, compliance, and security protocols.

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Cite this ( Beta Cell Biology Consortium , RRID:SCR_005136)

URL: http://www.betacell.org/

Resource Type: Resource, organization portal, resource, organism supplier, antibody supplier, database, biomaterial supply resource, biospecimen repository, experimental protocol, consortium, narrative resource, material resource, service resource, portal, storage service resource, cell repository, reagent supplier, data repository, material storage repository, data or information resource

THIS RESOURCE IS NO LONGER IN SERVICE, documented on August 1, 2015. Consortium that aims to facilitate interdisciplinary collaborations to advance the understanding of pancreatic islet development and function, with the goal of developing innovative therapies to correct the loss of beta cell mass in diabetes, including cell reprogramming, regeneration and replacement. They are responsible for collaboratively generating the necessary reagents, mouse strains, antibodies, assays, protocols, technologies and validation assays that are beyond the scope of any single research effort. The scientific goals for the BCBC are to: * Use cues from pancreatic development to directly differentiate pancreatic beta cells and islets from stem / progenitor cells for use in cell-replacement therapies for diabetes, * Determine how to stimulate beta cell regeneration in the adult pancreas as a basis for improving beta cell mass in diabetic patients, * Determine how to reprogram progenitor / adult cells into pancreatic beta-cells both in-vitro and in-vivo as a mean for developing cell-replacement therapies for diabetes, and * Investigate the progression of human type-1 diabetes using patient-derived cells and tissues transplanted in humanized mouse models. Many of the BCBC investigator-initiated projects involve reagent-generating activities that will benefit the larger scientific community. The combination of programs and activities should accelerate the pace of major new discoveries and progress within the field of beta cell biology.

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Cite this (BioJupies, RRID:SCR_016346)

URL: https://amp.pharm.mssm.edu/biojupies/

Resource Type: Resource, software resource, web application

Software as an open source web server that automatically generates RNA-seq data analysis of jupyter notebooks. It allows creation and containment of documents that have live code, visualizations and narrative text.

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Cite this (Clinical and Translational Science Awards Consortium, RRID:SCR_008339)

URL: https://www.ctsacentral.org/

Resource Type: Resource, knowledge environment

National consortium of medical research institutions working together to transform the local, regional, and national environment to increase the efficiency and speed of clinical and translational research across the country. Consortium members share a common vision to reduce the time it takes for laboratory discoveries to become treatments for patients, to engage communities in clinical research efforts and to train clinical and translational researchers. This consortium includes 60 medical research institutions located throughout the nation, linking them together to energize the discipline of clinical and translational science. The CTSA consortium has five Strategic Goals: * National Clinical and Translational Research Capability * The Training and Career Development of Clinical and Translational Scientists * Consortium-Wide Collaborations * The Health of our Communities and the Nation * T1 Translational Research

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Cite this ( Diabetes Research Centers , RRID:SCR_014535)

URL: https://diabetescenters.org/centers

Resource Type: Resource, disease-related portal, topical portal, resource, organization portal, portal, data or information resource

Diabetes Research Centers (DRC) is an integrated program of diabetes, endocrinology and metabolism research.

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Cite this (DIRECT2experts, RRID:SCR_013958)

URL: http://direct2experts.org

Resource Type: Resource, software resource, collaboration tool, portal, data or information resource

An on-going project and collaboration tool where biomedical researchers can access to expertise and related resources across institutions, regardless of local platforms and tools. Users can work with participating institutions in order to connect to their existing research networking tools. Biomedical institutions that wish to participate must have a mature, deployed research networking tool and can commit resources to assessments.

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Cite this (Drug Gene Budger, RRID:SCR_016489)

URL: http://amp.pharm.mssm.edu/DGB/

Resource Type: Resource, web service, software resource, data access protocol, web application

Web-based application to assist researchers with identifying drugs and small molecules that are predicted to maximally influence the expression of the mammalian gene of interest.
Used to identify drugs and small molecules to regulate expression of target genes for research purpose only.

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Cite this (Helmsley Cellular Research Hub, RRID:SCR_015546)

URL: https://www.cellhub.org/

Resource Type: Resource, biomaterial supply resource, material resource, cell repository

Cell repository that aims to share cell samples for the scientific advancement of Type 1 Diabetes research. Cell lines can be requested from their cell bank inventory.

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Cite this (International AMD Genetics Consortium, RRID:SCR_004009)

URL: http://eaglep.case.edu/iamdgc_web/

Resource Type: Resource, organization portal, portal, consortium, data or information resource

Consortium aiming to identify the remaining genetic risk variants for Age-related Macular Degeneration (AMD). To increase the statistical power needed to identify genes that have small, yet significant contributions to AMD, the consortium is conducting a meta-analysis on 15 Genome Wide Association Studies (GWAS) pooled from consortium members representing over 8,000 patients with advanced AMD (dry type, neovascular, or both) and 50,000 controls. In addition to verifying known genes, the consortium identified 19 new gene variants. The genes identified in these studies function in the immune system, cholesterol transport and metabolism, and formation and maintenance of connective tissue. This study provides a nearly complete picture of genetic heritability for AMD.

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Cite this (LINCS Information Framework, RRID:SCR_003937)

URL: http://lifekb.org/

Resource Type: Resource, data or information resource, database

Database for Library of Integrated Network-Based Cellular Signatures (LINCS) data that leverages semantic-web technologies and domain level ontologies. The NIH LINCS program aims to generate an extensive reference set of cellular response signatures to a variety of small molecule and genetic perturbations. The goal is to create a sustainable and widely accessible knowledge resource to advance understanding of the highly orchestrated interplay of molecular biological components in maintaining healthy development and how their perturbation causes disease. The data sets produced at LINCS span a variety of assay formats and technologies, including biochemical and single cell phenotypic responses, and genome-wide transcriptional profiling. This knowledge-based, extensible information system of interconnected components is designed to help scientists to use data and results produced in the LINCS and other NIH screening programs in their own research and to support their translation towards the development of novel therapeutics.

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Cite this (MIT Center for Biomedical Innovation, RRID:SCR_004027)

URL: http://cbi.mit.edu/

Resource Type: Resource, organization portal, portal, consortium, data or information resource

Consortium formed to improve global health by overcoming obstacles to the development and implementation of biomedical innovation. CBI provides a safe and transparent environment for collaborative research among industry, academia, and government, and draws on the expertise of the Massachusetts Institute of Technology''''s (MIT) Schools of Engineering, Science, and Management, as well as the Harvard-MIT Division of Health Sciences and Technology (HST). The center manages several consortia addressing a variety of challenges in the global biomedical industry by developing, testing, and disseminating new knowledge and tools designed for real world application through the following programs: the Biomanufacturing Program (BioMAN), the Consortium on Adventitious Agents in Biomanufacturing (CAACB), and New Drug Development Paradigms (NEWDIGS). The consortia managed by CBI include: * Biomanufacturing (BioMAN): a collaborative research and educational program in biotherapeutic manufacturing. The objective is to develop new knowledge, science, technologies and strategies that advance the manufacture and global delivery of high quality biopharmaceuticals. BioMAN activities bring together thought leaders from industry, the government/FDA and academia and involve faculty from across the Schools of Science, Engineering and Management at MIT * Consortium on Adventitious Agent Contamination in Biomanufacturing (CAACB): Their mission is to develop a comprehensive understanding of adventitious agents encountered in biomanufacturing, the sources of such agents, and a systematic, risk-based analysis of the most effective strategies and technologies to prevent contamination. * NEW Drug Development ParaDIGmS (NEWDIGS): focuses on transforming the current global pharmaceutical innovation ecosystem to more reliably and sustainably deliver new, better, affordable drugs to the right patients faster. System re-engineering projects are designed and executed with input from industry; regulators from US, Europe, Singapore, and Canada; payers and health technology assessment officials; providers, patients, and academic researchers from MIT, Harvard and other leading academic institutions.

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Cite this (New York University; New York; USA, RRID:SCR_011458)

URL: http://www.nyu.edu/

Resource Type: Resource, university, institution

  • From Current Category

    PAMGO

Cite this (PAMGO, RRID:SCR_000022)

URL: http://bmcmicrobiol.biomedcentral.com/articles/10.1186/1471-2180-9-S1-S1

Resource Type: Resource, ontology, data or information resource, controlled vocabulary

THIS RESOURCE IS NO LONGER IN SERVICE, documented on June 10, 2016. A consortium that created universal descriptors to describe functionally similar gene products and their attributes across all organisms. In 2004, the PAMGO interest group joined the GO consortium to extend the GO to include terms describing various processes related to microbe-host interactions. The organization uses a controlled vocabulary to set a process in place to describe plant associated microbes and their interactions with their plant-hosts. These higher order terms can describe gene products of all types of symbionts (e.g. parasites, commensals, and mutualists), including prokaryotes and eukaryotes that associate with plant or animal hosts. This initiative is a multi-institutional collaborative effort to pool information and research in: the bacteria Dickeya dadantii, Pseudomonas syringae pv tomato and Agrobacterium tumefaciens, the fungus Magnaporthe grisea, the oomycetes Phytophthora sojae and Phytophthora ramorum, and the nematode Meloidogyne hapla.

  • From Current Category

    Plotly

Cite this (Plotly, RRID:SCR_013991)

URL: https://plot.ly

Resource Type: Resource, software resource, collaboration tool, web application

A web application which allows users to collaboratively create interactive graphs and share them with others. Video tutorials are available for different users (engineers, data scientists, etc.) and types of graphs (histograms, bubble chart, in Excel, for the classroom, etc.). The JavaScript toolbox plotly.js enables users with little to no web development skills the ability to make scientific charts. There are three different packages for Plotly, as well as an enterprise edition. Demos and assistance is available for certain functions.

  • From Current Category

    ReadCube

Cite this (ReadCube, RRID:SCR_013777)

URL: https://www.readcube.com

Resource Type: Resource, software resource

A software resource application which organizes research literature. Users can import PDF articles into the application and create a searchable library. ReadCube enables users to perform keyword searches and provides references as well as note-taking tools. ReadCube also recommends articles to users based on library contents. For publishers, ReadCube enables interactive PDF versions of articles with tools for readers to make notes or perform author and keyword searches.

  • From Current Category

Cite this (Residual Variation Intolerance Score (RVIS), RRID:SCR_013850)

URL: http://chgv.org/GenicIntolerance/

Resource Type: Resource, narrative resource, standard specification, data or information resource

A gene-based score intended to help in the interpretation of human sequence data. The score is designed to rank genes in terms of whether they have more or less common functional genetic variation relative to the genome wide expectation given the amount of apparently neutral variation the gene has. A gene with a positive score has more common functional variation, and a gene with a negative score has less and is referred to as intolerant.

  • From Current Category

    Scizzle

Cite this (Scizzle, RRID:SCR_013781)

URL: http://www.myscizzle.com

Resource Type: Resource, software resource

A web application which finds new and relevant scientific literature based on keyword searches and filters. Users can also share, organize, and collaborate on papers using tools within Scizzle.

  • From Current Category

Cite this (University of Rochester; New York; USA, RRID:SCR_003821)

URL: http://www.rochester.edu/

Resource Type: Resource, university, institution

  • From Current Category

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