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on page 1 showing 20 out of 28 results from 1 sources

Cite this (Bloomington Drosophila Stock Center, RRID:SCR_006457)

URL: http://flystocks.bio.indiana.edu/bloomhome.htm

Resource Type: Resource, organism supplier, biomaterial supply resource, service resource, storage service resource, material resource, material storage repository

Database collects, maintains and distributes Drosophila melanogaster strains for research. Emphasis is placed on genetic tools that are useful to a broad range of investigations. These include basic stocks of flies used in genetic analysis such as marker, balancer, mapping, and transposon-tagging strains; mutant alleles of identified genes, including a large set of transposable element insertion alleles; defined sets of deficiencies and a variety of other chromosomal aberrations; engineered lines for somatic and germline clonal analysis; GAL4 and UAS lines for targeted gene expression; enhancer trap and lacZ-reporter strains with defined expression patterns for marking tissues; and a collection of transposon-induced lethal mutations. Approximately 29,000 fly strains are currently available. Up-to-date stock lists are available for searching, browsing, or downloading/copying at the Internet site. An order form is available on the same site. One small subculture is provided of each requested stock. Larger quantities of animals cannot be provided by the center. Requests may be submitted via a web-based automated ordering system. Stock center scientists are available to answer questions about center stocks, use of the database, or general questions about Drosophila genetics for researchers new to the field. New users of the collection must contact the center for a Bloomington user number (BUN) before ordering stocks.

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Cite this (Coriell Cell Repositories, RRID:SCR_003244)

URL: https://catalog.coriell.org/

Resource Type: Resource, production service resource, biomaterial supply resource, biospecimen repository, database, material service resource, service resource, storage service resource, cell repository, data or information resource, material resource, biomaterial manufacture, material storage repository

A biorepository and biomaterial supply resource which establishes, verifies, maintains, and distributes cells, cultures and DNA derived from cell cultures to the scientific community around the world. Scientists can browse the sample catalog and request specific cell lines for their research studies. An inventory of the remaining stock of each cell line and DNA preparation is presented in real time. Coriell's significant cell biobank collections include: NIGMS Human Genetic Cell Repository, NINDS Human Genetics DNA and Cell Line Repository, NIA Aging Cell Repository, NHGRI Sample Repository for Human Genetic Research, NEI Age-Related Eye Disease Study (AREDS) Genetic Repository, HD Community BioRepository, American Diabetes Association, GENNID Study, and Autism Research Resource. The repositories are ISO 9000-2001 compliant.

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Cite this ( GenitoUrinary Development Molecular Anatomy Project , RRID:SCR_001554)

URL: http://www.gudmap.org

Resource Type: Resource, organization portal, resource, organism supplier, database, biomaterial supply resource, consortium, standard specification, reference atlas, narrative resource, experimental protocol, portal, atlas, material resource, data or information resource

International consortium providing a molecular atlas of gene expression for the developing organs of the GenitoUrinary (GU) tract; a high resolution molecular anatomy highlighting development of the GU system; mouse strains to facilitate developmental and functional studies within the GU system; experimental protocols and standard specifications; tutorials describing GU organogenesis and primary data via the database. The data are from large-scale in situ hybridization screens (wholemount and section) and microarray gene expression data of microdissected, laser-captured and FACS-sorted components of the developing mouse genitourinary (GU) system. These expression data are annotated using a high-resolution anatomy ontology specific to the developing murine GU system.

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Cite this (Harvard Brain Tissue Resource Center, RRID:SCR_003316)

URL: http://www.brainbank.mclean.org/

Resource Type: Resource, biomaterial supply resource, biospecimen repository, tissue bank, service resource, brain bank, storage service resource, material resource, material storage repository

A biomaterial supply resource that acquires, processes, stores, and distributes postmortem brain specimens for brain research. Various types of brain tissue are collected, including those with neurological and psychiatric disorders, along with their parents, siblings and offspring. The HBTRC maintains an extensive collection of postmortem human brains from individuals with Huntington's chorea, Alzheimer's disease, Parkinson's disease, and other neurological disorders. In addition, the HBTRC also has a collection of normal-control specimens.

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Cite this (Honey Bee Brain EST Project, RRID:SCR_002389)

URL: http://titan.biotec.uiuc.edu/bee/honeybee_project.htm

Resource Type: Resource, biomaterial supply resource, data or information resource, material resource, database

A database integrating data from the bee brain EST sequencing project with data from sequencing and gene research projects from other organisms, primarily the fruit fly Drosophila melanogaster. The goal of Bee-ESTdb is to provide updated information on the genes of the honey bee, currently using annotation primarily from flies to suggest cellular roles, biological functions, and evolutionary relationships. The site allows searches by sequence ID, EST annotations, Gene Ontology terms, Contig ID and using BLAST. Very nice resource for those interested in comparative genomics of brain. A normalized unidirectional cDNA library was made in the laboratory of Prof. Bento Soares, University of Iowa. The library was subsequently subtracted. Over 20,000 cDNA clones were partially sequenced from the normalized and subtracted libraries at the Keck Center, resulting in 15,311 vector-trimmed, high-quality, sequences with an average read length of 494 bp. and average base-quality of 41. These sequences were assembled into 8966 putatively unique sequences, which were tested for similarity to sequences in the public databases with a variety of BLAST searches. The Clemson University Genomics Institute is the distributor of these public domain cDNA clones. For information on how to purchase an individual clone or the entire collection, please contact www.genome.clemson.edu/orders/ or generobi (at) life.uiuc.edu.

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Cite this (Human Brain and Spinal Fluid Resource Center, RRID:SCR_004811)

URL: http://brainbank.ucla.edu/

Resource Type: Resource, biomaterial supply resource, tissue bank, service resource, brain bank, storage service resource, material resource, material storage repository

A biomaterial supply resource which collects, stores, and distributes donated tissue to research scientists around the world. Collection occurs through the an anatomical donor program which accepts tissue donation from people with neurological/ psychiatric disorders. The Center also provides a continuous boost to biomedical research by providing high quality and quantity of pre- and post-mortem brains, spinal cords, cerebrospinal fluid (CSF), serum, blood cells and urine to use in investigations of neurological and psychiatric diseases. Scientists without a clinical site may use the Center''s readily available, high quality banked specimens.

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Cite this (International Mouse Strain Resource, RRID:SCR_001526)

URL: http://www.findmice.org/index.jsp

Resource Type: Resource, biomaterial supply resource, material resource, organism supplier, cell repository

Database of mouse strains and stocks available worldwide, that will assist the international research community in finding the mouse resources they need, including inbred, mutant, and genetically engineered mice. The IMSR is a multi-institutional international collaboration supporting the use of the mouse as a model system for studying human biology and disease. The IMSR began with an initial collaboration between the Mouse Genome Informatics (MGI) group at The Jackson Laboratory and the Medical Research Council Mammalian Genetics Unit at Harwell. Additional institutions and collaborators are now contributing mouse resource information to the IMSR. The data content found in the IMSR is as it was supplied by data provider sites. You are encouraged to participate in making this database as complete as possible for all worldwide mouse strain resources. If you or your institution hold mice, cryopreserved gametes or embryos, or ES cell lines that you distribute to other researchers, contributing information about them to the IMSR catalog will make them more widely known.

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Cite this ( Islet Cell Resource Centers , RRID:SCR_002806)

URL: http://icr.coh.org/

Resource Type: Resource, resource, production service resource, biomaterial supply resource, material service resource, service resource, cell repository, material resource, biomaterial manufacture

THIS RESOURCE IS NO LONGER IN SERVICE, documented on July 31, 2009. Group of 10 academic laboratories provide pancreatic islets of cGMP-quality to eligible investigators for use in FDA approved, IRB-approved transplantation protocols in which isolated human islets are transplanted into qualified patients afflicted with type 1 diabetes mellitus; optimize the harvest, purification, function, storage, and shipment of islets while developing tests that characterize the quality and predict the effectiveness of islets transplanted into patients with diabetes mellitus; and provide pancreatic islets for basic science studies. The centers are electronically linked through an Administrative and Bioinformatics Coordinating Center (ABCC). The ABCC manages a system with objectively defined criteria that establishes the order of priority for islet distribution. It also provides database and other informatics to track the utilization of pancreata and all distributed clinical grade islets for transplant and basic research, and supports the Islet Cell Resource Centers Consortium so that the research community has a single entry point to the program. Qualified researchers from domestic institutions may request islets by submitting a written application to the director of the ABCC. The ICRs will distribute Islets as appropriate for either clinical or basic science protocol use to eligible investigators who have received a favorable review and subsequent approval by the ICR Steering Committee (SC). The Administrative and Bioinformatics Coordinating Center (ABCC) manages the distribution according to a priority list. The ABCC will give preference to investigators who have peer-reviewed, NIH-funded research support.

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Cite this (Jackson Laboratory, RRID:SCR_004633)

URL: http://www.jax.org/index.html

Resource Type: Resource, production service resource, biomaterial supply resource, biomaterial manufacture, material service resource, service resource, material resource, institution

An independent, nonprofit organization focused on mammalian genetics research to advance human health. Their mission is to discover the genetic basis for preventing, treating, and curing human disease, and to enable research for the global biomedical community. Jackson Laboratory breeds and manages colonies of mice as resources for other research institutions and laboratories, along with providing software and techniques. Jackson Lab also conducts genetic research and provides educational material for various educational levels.

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Cite this (Louisiana Organ Procurement Agency - LOPA, RRID:SCR_004442)

URL: http://www.lopa.org

Resource Type: Resource, biomaterial supply resource, material resource, tissue bank

The Louisiana Organ Procurement Agency (LOPA) is the federally-designated organ procurement organization for the State of Louisiana. The agency focuses on educating the medical community and the general public about organ and tissue donation issues, working with families through the donation process, recovering donated organs and tissue, and placing the organs and tissue for transplant. Our mission is to save and enhance lives through organ and tissue donation. We envision a world in which no one suffers due to a lack of donor organs or tissues. LOPA has its main office in Metairie, with regional offices in Lafayette, and Shreveport. Additionally, LOPA has representatives in Baton Rouge, Alexandria, Lake Charles, and Monroe.

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Cite this (Mammalian Gene Collection, RRID:SCR_007024)

URL: http://mgc.nci.nih.gov/

Resource Type: Resource, biomaterial supply resource, material resource, cell repository

A trans-NIH initiative providing full-length open reading frame (FL-ORF) clones for human, mouse, and rat genes. In 2005, the project added the cow cDNAs generated by Genome Canada. MGC cDNA clones were obtained by screening of cDNA libraries, by transcript-specific RT-PCR cloning, and by DNA synthesis of cDNA inserts. All MGC sequences are deposited in GenBank and the clones can be purchased from distributors of the IMAGE consortium. You can use Download Plugin Adobe Acrobat Reader A Guide to Finding Mammalian Gene Collection (MGC) Clones and Evaluating Their Sequence to assist in determining whether MGC cDNA clones for human, mouse, or rat genes and transcripts of interest are available for purchase or sequence investigation. ORFeome Collaboration (OC) was formed to provide the research community with sequence-validated, full-ORF human cDNA clones in the Gateway vector format. * Total MGC full ORF clones: Human 29,818; Mouse 27,285; Rat 6,763; Bovine 9,104 * Non-redundant genes: Human 17,592; Mouse 17,701; Rat 6,486; Bovine 8,724 With the conclusion of the MGC project in March 2009, the GenBank records of MGC sequences will be frozen, without further updates. Since the definition of what constitutes a full-length coding region for some of the genes and transcripts for which they have MGC clones will likely change in the future, users planning to order MGC clones will need to monitor for these changes. Users can make use of genome browsers and gene-specific databases, such as the UCSC Genome browser, NCBI's Map Viewer, and Entrez Gene, to view the relevant regions of the genome (browsers) or gene-related information (Entrez Gene)

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Cite this (Manhattan HIV Brain Bank, RRID:SCR_010520)

URL: http://www.mssm.edu/research/programs/manhattan-hiv-brain-bank/

Resource Type: Resource, disease-related portal, topical portal, research forum portal, biomaterial supply resource, tissue bank, portal, brain bank, material resource, data or information resource

Biorepository of tissues and fluids relevant for the neurologic, neuropsychologic, psychiatric and neuropathologic manifestations of HIV infection, linked to medical records and an on-going clinical trial for research use by the scientific community. The MHBB conducts a longitudinal, observational study that follows a group of HIV-infected individuals who have agreed to be fluid and organ donors for the purposes of AIDS research. They are currently the largest, multidisciplinary neuroAIDS cohort in New York City, the epicenter of the US HIV epidemic. Research participants undergo regular neurologic, neuropsychologic, and psychiatric evaluations, and provide body fluid samples that are linked to clinical information. Upon their demise, study participants become organ donors. This program has supplied clinical information, tissue, and fluid samples to over 70 qualified AIDS researchers across America, Europe and Australia. In fulfilling its resource mission, the MHBB functions as part of the National NeuroAIDS Tissue Consortium (NNTC). MHBB provides a means by which people living with HIV can be engaged in the struggle to improve our knowledge about HIV infection and the damage it causes to the body.

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Cite this (Minnesota Liver Tissue Cell Distribution System, RRID:SCR_004840)

URL: http://www.med.umn.edu/peds/gi/ltcds/

Resource Type: Resource, biomaterial supply resource, material resource, tissue bank, cell repository

Provide human liver tissue from regional centers for distribution to scientific investigators throughout the United States. These USA regional centers have active liver transplant programs with human subjects approval to provide portions of the resected pathologic liver for which the transplant is performed. Frozen or fresh tissue is available from subcontractors for the usual forms of childhood and adult cirrhosis, fulminate liver failure, chronic rejection, and certain inborn errors of metabolism. In addition LTCDS provides normal human liver tissue (primarily frozen), slides, and tissue blocks, and rarely other liver cell types in culture. This service also provides isolated hepatocytes only to NIH investigators from normal human liver. NIH investigators are always given preference for tissue requests. Supporting letters for NIH new or renewal grant requests can be provided.

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Cite this ( Mouse Mutagenesis Center for Developmental Defects , RRID:SCR_007321)

URL: http://www.mouse-genome.bcm.tmc.edu/ENU/MutagenesisProj.asp

Resource Type: Resource, resource, organism supplier, production service resource, biomaterial supply resource, material service resource, service resource, material resource, biomaterial manufacture

THIS RESOURCE IS NO LONGER IN SERVICE. For updated mutant information, please visit MMRRC or The Jackson Laboratory. Produces, characterizes, and distributes mutant mouse strains with defects in embryonic and postembryonic development. The goal of the ENU Mutagenesis project III is to determine the function of genes on mouse Chromosome 11 by saturating the chromosome with recessive mutations. The distal 40 cM of mouse Chr 11 exhibits linkage conservation with human Chromosome 17. We are using the chemical N-ethyl-N-nitrosourea (ENU) to saturate wild type chromosomes with point mutations. By determining the function of genes on a mouse chromosome, we can extrapolate to predict function on a human chromosome. We expect many of the new mutants to represent models of human diseases such as birth defects, patterning defects, growth and endocrine defects, neurological anomalies, and blood defects. Because many of the mutations we expect to isolate may be lethal or detrimental to the mice, we are using a unique approach to isolate mutations. This approach uses a balancer chromosome that is homozygous lethal and carries a dominant coat color marker to suppress recombination over a reasonable interval.

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Cite this (National Institute on Drug Abuse Center for Genetic Studies, RRID:SCR_013061)

URL: http://zork.wustl.edu/nida/

Resource Type: Resource, data set, data or information resource

An umbrella site for the collection and distribution of clinical data related to the genetic analysis of drug abuse phenotypes. Anonymous data on family structure, age, sex, clinical status, and diagnosis (clinical data), DNA samples and cell line cultures (biomaterials), and data derived from genotyping and other genetic analyses of these clinical data and biomaterials (genetic analysis data), are distributed to qualified researchers studying the genetics of mental disorders and other complex diseases at recognized biomedical research facilities. Phenotypic and Genetic data will be made available to the general public on the release dates through distribution mechanisms specified on the website. Participating studies are as follows: * Genetics of Opioid Dependence * Mapping of Susceptibility Loci for Nicotine Dependence * Molecular Genetics of Heroin Dependence * Addictions: Genotypes, Polymorphisms, and Function * Genetics of Vulnerability to Nicotine Addiction * Family Study of Cocaine Dependence * Heroin Dependence * Differentiation of Phenotypes for Smoking * Pharmacokinetics of Nicotine in Twins * Adolescent Drug Dependence * Substance Abuse * Genetics of Cocaine Induced Psychosis * Genome-Wide Analysis for Addiction Susceptibility Genes * The Collaborative Genetic Study of Nicotine Dependence * Nicotine Dependence * Cocaine Dependence * Opiate Dependence: Candidate Genes and G x E Effects * Genetic Studies of Substance Abuse in Iowa Adoptees * Innovative Approaches for Cocaine Pharmacotherapy * Twin Family Study of Vulnerability to Substance Abuse * Drug Use * Substance Use Disorder Liability: Candidate Gene System * START (Starting Treatment with Agonist Replacement Therapies) * GEDI (The Genes, Environment, and Development Initiative) * GEDI (The Genes, Environment, and Development Initiative) * Youth Drug Abuse, ADHD and Related Disorders The investigators contact information, release dates, and description of the study are available on the website.

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Cite this (National Swine Resource and Research Center, RRID:SCR_006855)

URL: http://www.nsrrc.missouri.edu/

Resource Type: Resource, biomaterial supply resource, biospecimen repository, tissue bank, service resource, storage service resource, cell repository, material resource, material storage repository

Provides access to critically needed swine models of human health and disease as well as a central resource for reagents, creation of new genetically modified swine, and information and training related to use of swine models in biomedical research. Functions of the NSRRC include: * Importation: import existing swine models of human health and disease * Rederivation: eliminates pathogens and improves the quality of the animal model for research projects * Health Monitoring: perform on-going health monitoring to assure maintenance of a pathogen-free status * Cryopreservation: cryopreserve and store gametes, embryos and somatic cells to prevent loss of valuable models * Distribution: acts as a repository and distribution center for high quality, pathogen-free pigs * Research ** Improved techniques for cryopreservation of pig reproductive cells and tissues ** Improved methods for the detection and elimination of microbial pathogens in pigs ** Development of improved methods for the production of transgenic and knockout pigs

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Cite this (NIA Mutant Mouse Aging Colony Handbook, RRID:SCR_007328)

URL: http://www.nia.nih.gov/research/dab/nia-mutant-mouse-aging-colony-handbook

Resource Type: Resource, biomaterial supply resource, material resource, organism supplier

THIS RESOURCE IS NO LONGER IN SERVICE, documented on September 09, 2013. Supply aged mutant and transgenic mice for NIH-supported research directly related to the biology of aging. The mice are raised by the NIA's contractor, Taconic Farms, in Specific Pathogen-Free (SPF) barrier facilities. The strains in the mutant mouse aging colony have been donated by the investigators who developed the models, and those investigators are still the legally recognized owners of the intellectual property. A Material Transfer Agreement (MTA) is required to purchase the mice (a one-time requirement per strain). There are restrictions to the use of this colony as described in the MTA. These restrictions include a prohibition against breeding the mice purchased from the NIA Mutant Mouse Aging Colony, agreement that the mice will not be used for commercial purposes, and agreement that the mice and all derivatives will not be transferred to third parties. The restrictions are further spelled out in the MTA. Animals are sold by age, not weight, and ages are stated in 1 month intervals only; all animals born within a calendar month are considered to be the same age, so date of birth (DOB) is given as month/year. All mice are virgins. The mutant mouse aging colony is slated to end in September 2013. Old mice will be available until September 2013 but the availability of young mice will end earlier. Entries of different strains into the mutant mouse aging colony will end at different times, dependent on the lifespan and pattern of use of the strain. Mouse models include: * Snell Dwarf (3623) ??????????????? last entry will be the November 2011 DOB (date of birth) * Ames Dwarf (324) ??????????????? last entry will be the October 2012 DOB * A53T ???????????????????????-synuclein Transgenic (322) ??????????????? last entry will be the December 2012 DOB * GFP Transgenic (317) ??????????????? last entry will be the January 2013 DOB

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Cite this (NICHD Brain and Tissue Bank for Developmental Disorders, RRID:SCR_003601)

URL: http://medschool.umaryland.edu/btbank/

Resource Type: Resource, biomaterial supply resource, tissue bank, service resource, brain bank, storage service resource, material resource, material storage repository

The objective of this human tissue repository is to systematically collect, store, and distribute brain and other tissues for research dedicated to the improved understanding, care, and treatment of individuals with developmental disorders. Brain sections are primarily frozen in isopentane / dry ice. Tissues are stored in 10% formalin and frozen at -85 degrees C. Of special interest are individuals with Down syndrome and other chromosomal defects, mitochondrial encephalopathies, phenylketonuria and other aminoacidopathies, maternal PKU, Rett syndrome, leukodystrophies, lysosomal disorders, dyslexia, autism, and other neurodevelopmental disorders. The brain and tissue banks have extensive experience in arranging for the rapid retrieval of tissue upon the death of individuals who die while at home, in hospitals or hospice care. As a special service, the brain and tissue banks are able to assist researchers who are working with patients who intend to donate tissues at the time of their death. Immediately after retrieval of the tissue, the brain and tissue banks will forward needed tissue to the referring investigators and ensure proper storage and cataloging of any additional tissues as part of the brain and tissue banks. The recipient of tissue and the brain and tissue banks are required to sign a Tissue Transfer Agreement before any tissues are transferred.

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Cite this (NIH Human Pluripotent Stem Cell Registry, RRID:SCR_003149)

URL: http://stemcells.nih.gov/research/registry/

Resource Type: Resource, biomaterial supply resource, material resource, cell repository

A listing of human embryonic cell lines that are eligible for use in NIH funded research. Those lines that carry disease-specific mutations are noted as such under the line name. Total Eligible Lines = 200. The purpose of the Registry is to provide investigators with: # a unique NIH Code for each cell line that must be used when applying for NIH funding and # contact information to facilitate investigators' acquisition of stem cells. Before submitting a new grant application and supporting materials for consideration of a human embryonic stem cell line, scientists may wish to see what lines are already under consideration: * Human embryonic stem cell lines submitted to NIH that are being reviewed to determine if they may be used in NIH-supported research, http://grants.nih.gov/stem_cells/registry/pending.htm President George W. Bush required that the name of the registry be changed in his Executive Order #13435, issued on June 20, 2007. As a result of this Executive Order, the former National Institutes of Health Human Embryonic Stem Cell Registry will now be called the National Institutes of Health Human Pluripotent Stem Cell Registry. The registry will now include both human embryonic stem cells that were derived consistent with the President's policy of August 9, 2001 and human pluripotent stem cells derived from non-embryonic sources.

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Cite this (Rat Resource and Research Center, RRID:SCR_002044)

URL: http://www.rrrc.us/

Resource Type: Resource, organism supplier, biomaterial supply resource, biospecimen repository, tissue bank, service resource, storage service resource, cell repository, material resource, material storage repository

Supplies biomedical investigators with the rat models, embryonic stem cells, related reagents, and the protocols they require for their research. They provide a unique repository service to the biomedical community by importing, storing and distributing a vast number of rat strains; as well as performing research that improves the function of the Resource Center. In addition to repository, cryostorage and distribution functions, the RRRC can facilitate acquisition of rat strains from other international repositories as well as provide consultation and technical training to investigators using rat models.

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