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on page 1 showing 3 out of 3 results from 1 sources

Cite this (Federation of International Mouse Resources, RRID:SCR_006137)

URL: http://www.fimre.org/

Resource Type: Resource, topical portal, international standard specification, standard specification, narrative resource, portal, community building portal, data or information resource

The Federation of International Mouse Resources (FIMRe) is a collaborating group of Mouse Repository and Resource Centers worldwide whose collective goal is to archive and provide strains of mice as cryopreserved embryos and gametes, ES cell lines, and live breeding stock to the research community. Goals of the Federation of International Mouse Resources: * Coordinate repositories and resource centers to: ** archive valuable genetically defined mice and ES cell lines being created worldwide ** meet research demand for these genetically defined mice and ES cell lines * Establish consistent, highest quality animal health standards in all resource centers * Provide genetic verification and quality control for genetic background and mutations * Provide resource training to enhance user ability to utilize cryopreserved resources

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Cite this (MGI strains, RRID:SCR_012950)

URL: http://www.informatics.jax.org/external/festing/mouse/STRAINS.shtml

Resource Type: Resource, data set, data or information resource

A list of major inbred mouse strains from the Jackson laboratories. This list is not being actively maintained (found on Nov 27, 2013).

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Cite this ( Mouse Mutagenesis Center for Developmental Defects , RRID:SCR_007321)

URL: http://www.mouse-genome.bcm.tmc.edu/ENU/MutagenesisProj.asp

Resource Type: Resource, resource, organism supplier, production service resource, biomaterial supply resource, material service resource, service resource, material resource, biomaterial manufacture

THIS RESOURCE IS NO LONGER IN SERVICE. For updated mutant information, please visit MMRRC or The Jackson Laboratory. Produces, characterizes, and distributes mutant mouse strains with defects in embryonic and postembryonic development. The goal of the ENU Mutagenesis project III is to determine the function of genes on mouse Chromosome 11 by saturating the chromosome with recessive mutations. The distal 40 cM of mouse Chr 11 exhibits linkage conservation with human Chromosome 17. We are using the chemical N-ethyl-N-nitrosourea (ENU) to saturate wild type chromosomes with point mutations. By determining the function of genes on a mouse chromosome, we can extrapolate to predict function on a human chromosome. We expect many of the new mutants to represent models of human diseases such as birth defects, patterning defects, growth and endocrine defects, neurological anomalies, and blood defects. Because many of the mutations we expect to isolate may be lethal or detrimental to the mice, we are using a unique approach to isolate mutations. This approach uses a balancer chromosome that is homozygous lethal and carries a dominant coat color marker to suppress recombination over a reasonable interval.

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